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Research
Latest papers
Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors.
Nature communications · 2025
Design, Synthesis, and In Vitro Characterization of Proteolytically-Stable Opioid-Neurotensin Hybrid Peptidomimetics.
ACS pharmacology & translational science · 2024
The P2Y6 receptor signals through Gαq /Ca2+ /PKCα and Gα13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration.
Journal of cellular physiology · 2020
4 publications.
Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors.
Nepveu-Traversy ME, Hassanzadeh M, Bruneau-Cossette L, Besserer-Offroy É, Brouillette R, Morissette S, Traboulsi H, Kirby K, Murza A, Longpré JM, Breton B, Gendron FP, Gaudreau S, Boudreault PL, Sarret P
Design, Synthesis, and In Vitro Characterization of Proteolytically-Stable Opioid-Neurotensin Hybrid Peptidomimetics.
De Neve J, Breault É, Previti S, Vangeloven E, Loranger B, Chartier M, Brouillette R, Lanoie A, Holleran BJ, Longpré JM, Gendron L, Tourwé D, Sarret P, Ballet S
The P2Y6 receptor signals through Gαq /Ca2+ /PKCα and Gα13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration.
Girard M, Dagenais Bellefeuille S, Eiselt É, Brouillette R, Placet M, Arguin G, Longpré JM, Sarret P, Gendron FP
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs.
Luginina A, Gusach A, Marin E, Mishin A, Brouillette R, Popov P, Shiriaeva A, Besserer-Offroy É, Longpré JM, Lyapina E, Ishchenko A, Patel N, Polovinkin V, Safronova N, Bogorodskiy A, Edelweiss E, Hu H, Weierstall U, Liu W, Batyuk A, Gordeliy V, Han GW, Sarret P, Katritch V, Borshchevskiy V, Cherezov V
Journée Phare 2017
Principal investigators: Brouillette, Rebecca
Keywords: Biotechnologie; Cancer; Collaborations Interdisciplinaires; Immunologie; Neurosciences; Pharmacologie; Recherche Biomédicale; Santé Humaine; Vulgarisation Scientifique; Étudiants-Chercheurs
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Obstétrique et gynécologie
- Anatomie et biologie cellulaire
- Médecine
- Pharmacologie - Physiologie
- Other
Co-authors at Université de Sherbrooke, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
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