Faculty profile
Fernand-Pierre Gendron
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Sherbrooke directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors.
Nature communications · 2025
Ligand-dependent intracellular trafficking of the G protein-coupled P2Y6 receptor.
Biochimica et biophysica acta. Molecular cell research · 2023 · senior author
The expression of P2Y6 receptor promotes the quality of mucus in colitic mice.
The FEBS journal · 2021 · senior author
Latest funding
- $15,000
Chronic Inflammation, Immunity and Cancer 2019
CIHR · 2019 · Co-investigator
- $192,000
Elucidating alternative leucine-rich G protein coupled receptor-5 (Lgr5) signaling
NSERC · 2019 · Principal investigator
- $147,500
High-throughput protein immunolocalization analysis through virtual fluorescence imaging.
NSERC · 2015 · Principal investigator
30 publications.
Structure-based design of macrocyclic peptides to generate functional antibodies against G protein-coupled receptors.
Nepveu-Traversy ME, Hassanzadeh M, Bruneau-Cossette L, Besserer-Offroy É, Brouillette R, Morissette S, Traboulsi H, Kirby K, Murza A, Longpré JM, Breton B, Gendron FP, Gaudreau S, Boudreault PL, Sarret P
Ligand-dependent intracellular trafficking of the G protein-coupled P2Y6 receptor.
Girard M, Bellefeuille SD, Eiselt É, Arguin G, Longpré JM, Sarret P, Gendron FP
The expression of P2Y6 receptor promotes the quality of mucus in colitic mice.
Placet M, Molle CM, Arguin G, Geha S, Gendron FP
A novel class of inhibitors that target SRSF10 and promote p53-mediated cytotoxicity on human colorectal cancer cells.
Sohail M, Shkreta L, Toutant J, Rabea S, Babeu JP, Huard C, Coulombe-Huntington J, Delannoy A, Placet M, Geha S, Gendron FP, Boudreau F, Tyers M, Grierson DS, Chabot B
Expression and function of the P2X7 receptor in human osteoblasts: The role of NFATc1 transcription factor.
Bergamin LS, Penolazzi L, Lambertini E, Falzoni S, Sarti AC, Molle CM, Gendron FP, De Bonis P, Di Virgilio F, Piva R
The P2Y6 receptor signals through Gαq /Ca2+ /PKCα and Gα13 /ROCK pathways to drive the formation of membrane protrusions and dictate cell migration.
Girard M, Dagenais Bellefeuille S, Eiselt É, Brouillette R, Placet M, Arguin G, Longpré JM, Sarret P, Gendron FP
The expression of the P2Y6 receptor is regulated at the transcriptional level by p53.
Molle CM, Arguin G, Jemfer C, Placet M, Dagenais Bellefeuille S, Gendron FP
Structure-activity relationship study of NPP1 inhibitors based on uracil-N1-(methoxy)ethyl-β-phosphate scaffold.
Nassir M, Pelletier J, Arad U, Arguin G, Khazanov N, Gendron FP, Sévigny J, Senderowitz H, Fischer B
Reviewing the role of P2Y receptors in specific gastrointestinal cancers.
Bellefeuille SD, Molle CM, Gendron FP
Highly Selective and Potent Ectonucleotide Pyrophosphatase-1 (NPP1) Inhibitors Based on Uridine 5'-Pα,α-Dithiophosphate Analogues.
Zelikman V, Pelletier J, Simhaev L, Sela A, Gendron FP, Arguin G, Senderowitz H, Sévigny J, Fischer B
Chronic Inflammation, Immunity and Cancer 2019
Principal investigators: Boudreau, François
Keywords: Biological Models; Digestive Cancer; Immunotherapy; Inflammatory Bowel Diseases; Mechanisms Of Inflammation; Microbiome
Elucidating alternative leucine-rich G protein coupled receptor-5 (Lgr5) signaling
Principal investigators: Gendron, FernandPierre
High-throughput protein immunolocalization analysis through virtual fluorescence imaging.
Principal investigators: Gendron, FernandPierre
Characterization of the mechanism regulating P2X7 expression and functions in intestinal epithelial cells.
Principal investigators: Gendron, FernandPierre
Regulation and role of P2Y6 nucleotide receptor in colorectal cancer
Principal investigators: Gendron, Fernand-Pierre
Keywords: Animal And Cell Models; Cell Invasion; Cell Survival; Colorectal Cancer; Epigenetic Regulation; Epithelial Cells; Extracellular Nucleotides; Gpcr; Transcription Factor; Tumorigenesis
Role of epithelial cells P2Y receptors in the dysfunction of the intestinal mucosa during inflammation.
Principal investigators: Gendron, Fernand-Pierre
Keywords: Animal Models; Cellular And Molecular Biology; Cytokines; Intestinal Inflammation; Receptors And Signal Transduction; Transcription
Role of the P2X7 nucleotide receptor in intestinal epithelial cell proliferation and differentiation
Principal investigators: Gendron, FernandPierre
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Philippe Sarret and Pierre-Luc Boudreault: 15 shared papers
- Nathalie Perreault and Nathalie Rivard: 13 shared papers
- François Boudreau and Nathalie Perreault: 5 shared papers
- Philippe Sarret and Rebecca Brouillette: 4 shared papers
- Philippe Sarret and Fernand-Pierre Gendron: 3 shared papers
- Nathalie Perreault and Alfredo Menendez: 3 shared papers
- Elena Verdu and Nathalie Perreault: 2 shared papers
- Elena Verdu and Nathalie Rivard: 2 shared papers
- Fernand-Pierre Gendron and François Boudreau: 2 shared papers
- Fernand-Pierre Gendron and Nathalie Perreault: 2 shared papers
- Fernand-Pierre Gendron and Jana Stankova: 2 shared papers
- Fernand-Pierre Gendron and Nathalie Rivard: 2 shared papers
- Fernand-Pierre Gendron and Rebecca Brouillette: 2 shared papers
- François Boudreau and Nathalie Rivard: 2 shared papers
- François Boudreau and Alfredo Menendez: 2 shared papers
- Nathalie Rivard and Alfredo Menendez: 2 shared papers
- Elena Verdu and Fernand-Pierre Gendron: 1 shared paper
- Fernand-Pierre Gendron and Benoit Chabot: 1 shared paper
- Fernand-Pierre Gendron and Alfredo Menendez: 1 shared paper
- Fernand-Pierre Gendron and Pierre-Luc Boudreault: 1 shared paper
- Benoit Chabot and Pierre-Luc Boudreault: 1 shared paper
- Jana Stankova and Alfredo Menendez: 1 shared paper
- Rebecca Brouillette and Pierre-Luc Boudreault: 1 shared paper
- Anatomie et biologie cellulaire
- Immunologie-Biologie Cellulaire
- Microbiologie et d'infectiologie
- Obstétrique et gynécologie
- Pediatrics/Immunology
- Medicine
- Pharmacologie - Physiologie
- Other
Co-authors at Université de Sherbrooke, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Philippe Sarret
Obstétrique et gynécologie
3 shared papers, latest 2025
François Boudreau
Immunologie-Biologie Cellulaire
2 shared papers, latest 2018
Jana Stankova
Pediatrics/Immunology
2 shared papers, latest 2013
Nathalie Rivard
Immunologie-Biologie Cellulaire
2 shared papers, latest 2007
Rebecca Brouillette
Faculty
2 shared papers, latest 2025
Nathalie Perreault
Anatomie et biologie cellulaire
2 shared papers, latest 2016
Benoit Chabot
Microbiologie et d'infectiologie
1 shared papers, latest 2021
Pierre-Luc Boudreault
Pharmacologie - Physiologie
1 shared papers, latest 2025
Alfredo Menendez
Microbiologie et d'infectiologie
1 shared papers, latest 2016
Elena Verdu
Medicine
1 shared papers, latest 2009
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