Faculty profile

Kristi Baker

ResearcherOncologyUniversity of Alberta

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.

Kristi Baker

Researcher

Oncology

Health Sciences

University of Alberta

Edmonton, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
12 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (4 CIHR, 1 NSERC), most recently in 2025.
Supervised 5 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Colorectal Cancer (Crc)Cancer Antigen Cross-Presentation Antitumor Immunity Dendritic Cell (Dc)Igg Immune Complex Microsatellite Instability (Msi)Neoantigen

Latest papers

Cytosolic DNA structures produced by mismatch repair deficiency coordinate anti-tumor immunity in colorectal cancer.
Cell reports · 2026 · senior author
Correction: Short chain fatty acids prime colorectal cancer cells to activate antitumor immunity.
Frontiers in immunology · 2025 · senior author
Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality.
Cell genomics · 2025

All 17 publications

Latest funding

Assessing DGK Alpha as the Key Target for a Promising Immunomodulatory Compound: Mechanism and Implications in cancer immunotherapy
CIHR · 2025 · Co-investigator
$738,226
Effect of mtDNA and gDNA on Immune Cell Activation in Colorectal Cancer Subtypes
CIHR · 2025 · Supervisor
$1,500
Genomic instability regulates STING mediated anti-tumor immunity through distinctive cytosolic DNA structures
CIHR · 2025 · Supervisor
$1,500

All 18 grants and awards

17 publications.

Cytosolic DNA structures produced by mismatch repair deficiency coordinate anti-tumor immunity in colorectal cancer.

Mosley SR, Lapa N, Namdar A, Catley TE, Meier-Stephenson F, Mowat C, Gao P, Sun X, Meier-Stephenson V, Pyne ALB, Baker K

Cell reports2026Senior author

DOI: 10.1016/j.celrep.2026.117012 PMID: 41722050

Correction: Short chain fatty acids prime colorectal cancer cells to activate antitumor immunity.

Mowat C, Dhatt J, Bhatti I, Hamie A, Baker K

Frontiers in immunology2025Senior author

DOI: 10.3389/fimmu.2025.1700962 PMID: 41041312

Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality.

Cunningham CE, Vizeacoumar FS, Zhang Y, Kyrylenko L, Both S, Maranda V, Dong H, Price JDW, Gao P, Wagner K, Wu Y, Lazell-Wright M, Ganapathysamy A, Hari R, Bhanumathy KK, Denomy C, Saxena A, Vizeacoumar JP, Morales AM, Khan F, Mosley S, Chen A, Katrii T, Zoller BGE, Rajamanickam K, Walke P, Gong L, Patel H, Elhasasna H, Dahiya R, Abuhussein O, Dmitriev A, Freywald T, Munhoz EP, Ruppin E, Lee JS, Rox K, Koebel M, Hopkins L, Lee CH, Yadav S, Gasparoni G, Walter J, Krishnan A, Datla R, Toosi B, Baker K, Meens J, Cescon DW, Ailles L, Leary SC, Wu Y, Empting M, Kiemer AK, Freywald A, Vizeacoumar FJ

Cell genomics2025

DOI: 10.1016/j.xgen.2025.100876 PMID: 40347943

NLRP3 activation promotes cGAS/STING signaling and antitumor immunity by colorectal cancer cells.

Mowat C, Schiller D, Baker K

Cancer immunology, immunotherapy : CII2025Senior author

DOI: 10.1007/s00262-025-04088-y PMID: 40481953

Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity.

Mosley SR, Chen A, Doell DNW, Choi S, Mowat C, Meier-Stephenson F, Meier-Stephenson V, Baker K

Cell reports2025Senior author

DOI: 10.1016/j.celrep.2024.115177 PMID: 39864057

Real-world evidence of sotrovimab effectiveness for preventing severe outcomes in patients with COVID-19: A quality improvement propensity-matched retrospective cohort study of a pan-provincial program in Alberta, Canada.

Farmer G, Sikdar KC, Lo T, Conly J, Slobodan J, Ross J, James S, Usman H, Kemp K, Baker K, Doucette K, Nijssen-Jordan C, Saxinger LM, Joffe AM

International journal of infectious diseases : IJID : official publication of the International Society for Infectious Diseases2024

DOI: 10.1016/j.ijid.2024.107136 PMID: 38880123

Peroxisomal cholesterol metabolism regulates yap-signaling, which maintains intestinal epithelial barrier function and is altered in Crohn's disease.

Pinelli M, Makdissi S, Scur M, Parsons BD, Baker K, Otley A, MacIntyre B, Nguyen HD, Kim PK, Stadnyk AW, Di Cara F

Cell death & disease2024

DOI: 10.1038/s41419-024-06925-x PMID: 39069546

Hsp90 inhibition leads to an increase in surface expression of multiple immunological receptors in cancer cells.

Wickenberg M, Mercier R, Yap M, Walker J, Baker K, LaPointe P

Frontiers in molecular biosciences2024

DOI: 10.3389/fmolb.2024.1334876 PMID: 38645275

Activin A-Expressing Polymorphonuclear Myeloid-Derived Suppressor Cells Infiltrate Skeletal and Cardiac Muscle and Promote Cancer Cachexia.

Dzierlega K, Chakraborty M, Lee M, Soliman AM, Parker D, Khan S, Chan YT, Akbari M, Yokota T, Winer S, Baker K, Tsai S, Winer DA, Clemente-Casares X

Journal of immunology (Baltimore, Md. : 1950)2023

DOI: 10.4049/jimmunol.2200064 PMID: 37294291

Short chain fatty acids prime colorectal cancer cells to activate antitumor immunity.

Mowat C, Dhatt J, Bhatti I, Hamie A, Baker K

Frontiers in immunology2023Senior author

DOI: 10.3389/fimmu.2023.1190810 PMID: 37304266

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Kristi Baker

Research

Latest papers

Latest funding

Cytosolic DNA structures produced by mismatch repair deficiency coordinate anti-tumor immunity in colorectal cancer.

Correction: Short chain fatty acids prime colorectal cancer cells to activate antitumor immunity.

Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality.

NLRP3 activation promotes cGAS/STING signaling and antitumor immunity by colorectal cancer cells.

Cytosolic DNA composition is determined by genomic instability mechanism and regulates dendritic cell-mediated anti-tumor immunity.

Real-world evidence of sotrovimab effectiveness for preventing severe outcomes in patients with COVID-19: A quality improvement propensity-matched retrospective cohort study of a pan-provincial program in Alberta, Canada.

Peroxisomal cholesterol metabolism regulates yap-signaling, which maintains intestinal epithelial barrier function and is altered in Crohn's disease.

Hsp90 inhibition leads to an increase in surface expression of multiple immunological receptors in cancer cells.

Activin A-Expressing Polymorphonuclear Myeloid-Derived Suppressor Cells Infiltrate Skeletal and Cardiac Muscle and Promote Cancer Cachexia.

Short chain fatty acids prime colorectal cancer cells to activate antitumor immunity.

Assessing DGK Alpha as the Key Target for a Promising Immunomodulatory Compound: Mechanism and Implications in cancer immunotherapy

Effect of mtDNA and gDNA on Immune Cell Activation in Colorectal Cancer Subtypes

Genomic instability regulates STING mediated anti-tumor immunity through distinctive cytosolic DNA structures

Polynucleotide kinase/phosphatase: its role in DNA strand break repair and a potential cancer therapeutic target

Identifying anatomical site-specific drivers of antitumor immunity in cancer

Nano-carriers of novel inhibitors of DNA repair for enhanced therapy in unresectable lung cancer

Metabolic Effects on Immune Response of TFAM Truncated Colorectal Cancer

Characteristic cytosolic DNA patterns produced by genomic instability induce anti-tumour immunity via cGAS/STING in colorectal cancer

Role of TFAM in cGAS/STING Mediated Anti-Tumor Immunity of MSI Colorectal Cancer

The Role of CSF2RB1 Ligands in Cancer-Associated Cachexia

Frequent collaborators

Vanessa Meier-Stephenson

Francesca Di Cara

Sue Tsai

Paul LaPointe

Anand Krishnan

Catherine Field

Bruce Vallance

Laurie Ailles

Toshifumi Yokota

Andrew Freywald

Simon Hirota

Vera Mazurak

Anthony Otley

John Conly

Kerry Courneya