Faculty profile

Alyson Kelvin

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Associate ProfessorSnyder Institute for Chronic DiseasesUniversity of Calgary

Alyson Kelvin

Associate Professor

Snyder Institute for Chronic Diseases

University of Calgary

Calgary, Alberta, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
46 publications in the last five years, latest in 2026.
Senior (last) author on 9 recent papers, a sign of leading a research group.
Principal investigator on 12 research grants (11 CIHR, 1 CFI), most recently in 2025.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

113

Publications

4,014

Citations

Collaborators

Grants

Publications by year

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Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Calgary profile.

Preclinical Models One Health Antigenic Mapping B Cell Development Coronavirus Cross-Reactive Responses Pan-Coronavirus Vaccine Vaccine Development

Latest papers

Case presentation of patients hospitalised with mpox (subclade Ib/2023sh) including children, adolescents, and adults in South Kivu, Democratic Republic of the Congo: an observational cohort study.
The Lancet. Infectious diseases · 2026
MPXV Clade IIb virus infection in mice leads to prolonged viral replication, macrophage infiltration, and decreased spermatogenesis in the testes
Research Square · 2026 · senior author
MassIVE MSV000100569 - GNPS Pansarbecovirus Fusion Protein Vaccine Candidates
UC San Diego · 2026 · first author

All 113 publications

Latest funding

Enhancing surveillance and detection of Mpox across Africa
CIHR · 2025 · Co-investigator
$350,000
Influenza Pathogenesis and the Development of Anticipatory Universal Vaccines for Canadian Pandemic Preparedness
CFI · 2025 · Principal investigator
$131,000
Leveraging the Ferret Model for understanding H5N1 2.3.4.4b virus pathogenesis in preimmune populations and mammary glands
CIHR · 2024 · Nominated PI
$150,000

All 19 grants and awards

113 publications.

Case presentation of patients hospitalised with mpox (subclade Ib/2023sh) including children, adolescents, and adults in South Kivu, Democratic Republic of the Congo: an observational cohort study.

Flores Girón L, Sganzerla Martinez G, Daniel BN, Bisimwa AK, Pacific N, Martin GA, Kabwana JCA, Kumar A, Toloue Ostadgavahi A, Dutt M, Bénite KL, Damien MH, Gortázar C, Abu-Raya B, Kelvin AA, Prince KK, Kelvin DJ

The Lancet. Infectious diseases20262 citationsOpen Access

DOI: 10.1016/s1473-3099(26)00051-4 PMID: 41819118

MPXV Clade IIb virus infection in mice leads to prolonged viral replication, macrophage infiltration, and decreased spermatogenesis in the testes

CL Swan, Gustavo Sganzerla Martinez, Mia Madel Alfajaro, Angela L. Rasmussen, David J. Kelvin, David A. Price Evans, Jason Kindrachuk, Ryan S. Noyce, Alyson A. Kelvin

Research Square2026Senior authorOpen Access

DOI: 10.21203/rs.3.rs-8895889/v1

MassIVE MSV000100569 - GNPS Pansarbecovirus Fusion Protein Vaccine Candidates

Alyson A. Kelvin

UC San Diego2026First authorOpen Access

DOI: 10.25345/c50k26r1z

Fusion protein pan-sarbecovirus vaccines elicit broadly protective immune responses targeting Clade 1a, 1b, and 3 sarbecoviruses

Alyson A. Kelvin, Matthew Brian Rogers, Zahed Katooni, Eva-Maria E. Uhlemann, Rachelle M. Buchanan, Erin Scruten, Anthony Yourkowski, Jocelyne M. Lew, Akarin Asavajaru, Jill van Kessel, Paul L. Pennington, Andrea Kroeker, Cynthia L. Swan, Rinku Patel, Brittany M. Thivierge, Willian Deck, Ravendra Garg, Glenn Hamonic, Wolfgang L. Köster, Tracy Prysliak, Anne-Catherine Fluckiger, Jasminka Bozic, Andrew Van Kessel, Volker Gerdts, Qiang Liu, Arinjay Banerjee, Darryl Falzarano, Trina Racine

Research Square2026First authorOpen Access

DOI: 10.21203/rs.3.rs-8544714/v1

Influenza infection of the mammary gland

Alyson A. Kelvin, Pari Baker, Sourish Ghosh, Stacey Schultz‐Cherry, Stephanie N. Langel

Journal of Virology20254 citationsFirst authorOpen Access

DOI: 10.1128/jvi.01940-24 PMID: 40793789

Inhibitory effects of bioactive molecules against nonstructural protein (NSs) of Rift Valley Fever Virus (RVFv): A molecular modeling study

Mansi Dutt, Anuj Kumar, Budheswar Dehury, Gustavo Sganzerla Martinez, Rohit Shukla, Sarbani Mishra, Krishna Pal Singh, Alyson A. Kelvin, David J. Kelvin

Heliyon20253 citationsOpen Access

DOI: 10.1016/j.heliyon.2025.e42895

Partial deletion of the OPG164 (A36R) transmembrane phosphoprotein in monkeypox virus clade Ib/sh2023 disrupts the active region involving Tyr140

Anuj Kumar, Gustavo Sganzerla Martinez, Mansi Dutt, Ali Toloue Ostadgavahi, Alyson A. Kelvin, David J. Kelvin

The Lancet Microbe20251 citationsOpen Access

DOI: 10.1016/j.lanmic.2025.101223 PMID: 40889505

MPXV Clade IIb virus infection in mice leads to prolonged viral replication, macrophage infiltration, and decreased spermatogenesis in the testes

Cynthia L. Swan, Gustavo Sganzerla Martinez, Mia Madel Alfajaro, Angela L. Rasmussen, David J. Kelvin, David H. Evans, Jason Kindrachuk, Ryan S. Noyce, Alyson A. Kelvin

bioRxiv (Cold Spring Harbor Laboratory)2025Senior authorOpen Access

DOI: 10.64898/2025.12.16.694558

Complete Genome Sequencing, Annotation, and Mutational Profiling of the Novel Clade I Human Mpox Virus, Kamituga Strain

Leandre Murhula Masirika, Anuj Kumar, Mansi Dutt, Ali Toloue Ostadgavahi, Benjamin Hewins, Maliyamungu Bubala Nadine, Bilembo Kitwanda Steeven, Franklin Kumbana Mweshi, Léandre Mutimbwa Mambo, Justin Bengehya Mbiribindi, Freddy Belesi Siangoli, Alyson A. Kelvin, Jean Claude Udahemuka, Patricia Kelvin, Luis Emilio Flores, David J. Kelvin, Gustavo Sganzerla Martinez

The Journal of Infection in Developing Countries202447 citationsOpen Access

DOI: 10.3855/jidc.20136 PMID: 38728644

Epidemiology, clinical characteristics, and transmission patterns of a novel Mpox (Monkeypox) outbreak in eastern Democratic Republic of the Congo (DRC): an observational, cross-sectional cohort study

Leandre Murhula Masirika, Jean Claude Udahemuka, Pacifique Ndishimye, Gustavo Sganzerla Martinez, Patricia Kelvin, Maliyamungu Bubala Nadine, Bilembo Kitwanda Steeven, Franklin Kumbana Mweshi, Léandre Mutimbwa Mambo, Bas B. Oude Munnink, Justin Bengehya Mbiribindi, Freddy Belesi Siangoli, Trudie A. Lang, Jean Malekani, Frank M. Aarestrup, Marion Koopmans, Leonard Schuele, Jean Pierre Musabvimana, Brigitte Umutoni, Ali Toloue Ostadgavahi, Benjamin Hewins, Mansi Dutt, Anuj Kumar, Alyson A. Kelvin, Jean-Paul Kabemba Lukusa, Christian Gortázar, David J. Kelvin, Luis Emilio Flores

medRxiv202424 citationsOpen Access

DOI: 10.1101/2024.03.05.24303395

Enhancing surveillance and detection of Mpox across Africa

Co-investigatorCIHR2025Team Grant: Monkeypox Rapid Research Response - Extension

Principal investigators: Kindrachuk, Kenneth J; Ansumana, Rashid; Mbala, Placide K

Keywords: Clades; Clinical Outcomes; Correlates Of Protection; Endemic; Monkeypox; Mpox; Publice Health; Serology; Surveillance; Vaccine Effectiveness

$350,000

Influenza Pathogenesis and the Development of Anticipatory Universal Vaccines for Canadian Pandemic Preparedness

Principal investigatorCFI2025John R. Evans Leaders Fund: John R. Evans Leaders Fund – Funding for research infrastructure

Principal investigators: Kelvin, Alyson

Keywords: in vivo; respiratory virus; preclinical model; vaccine; respiratory tract; mucosal delivery; influenza virus; coronavirus; vaccine development; pandemic; biobubble; CL2ag; CL2+; virus suite; containment room;

$131,000

Leveraging the Ferret Model for understanding H5N1 2.3.4.4b virus pathogenesis in preimmune populations and mammary glands

Nominated PICIHR2024Catalyst Grant: Avian Influenza OneHealth Research

Principal investigators: Kelvin, Alyson A

Keywords: H5n1; Imprinting; Influenza Virus; Lactating Mammary Gland; Maternal Immunity; One Health; Outbreak; Pandemic; Pre-Existing Immunity; Respiratory Virus

$150,000

Regulation of coronavirus cross-reactivity and immune durability for pan-coronavirus vaccine development

Nominated PICIHR2023Project Grant

Principal investigators: Kelvin, Alyson A

Keywords: Affinity Maturation; Antigenic Mapping; B Cell Development; Coronavirus; Correlates Of Cross-Protection; Cross-Reactive Responses; Germinal Center; Pan-Coronavirus Vaccine; Preclinical Models; Vaccine Development

$906,526

Investigation of Mpox virus spillover and spillback at the human-animal interface in the Democratic Republic of Congo

Nominated PICIHR2023Team Grant: Mpox (monkeypox) and zoonotic threats - Ecological and zoonotic pool

Principal investigators: Kelvin, Alyson A; Forbes, Kristian M; Kindrachuk, Kenneth J; Rimoin, Anne W

Keywords: Human-Animal Interface; Monkeypox; Mpox; Mpox Virus; One Health; Public Health; Reservoir Species; Surviellance; Virus; Virus Transmission

$500,000

Strengthening global and regional health security through surveillance of emerging Poxviruses in humans, domestic and peri-domestic animals, and wildlife

Co-investigatorCIHR2023Team Grant: Mpox (monkeypox) and zoonotic threats - Ecological and zoonotic pool

Principal investigators: Kelvin, David J

Keywords: Monkeypox; Mpox Virus; Pox Virus

$500,000

A prospective and retrospective multi-center, cohort study for clinical, virologic and immunologic characterization of monkeypox virus clade IIb by the International Monkeypox Response Consortium (IMREC)

Co-investigatorCIHR2022Team Grant: Monkeypox Rapid Research Response

Principal investigators: Kindrachuk, Kenneth J; Ansumana, Rashid; Mbala, Placide K

Keywords: Clades; Clinical Outcomes; Correlates Of Protection; Endemic; Monkeypox Virus; Public Health; Serology; Surveillance; Vaccine Effectiveness

$1,840,500

Preclinical Models for Monkeypox Virus Infection and Therapeutic Development

Nominated PICIHR2022Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Kelvin, Alyson A; Evans, David H; Kelvin, David J; Kindrachuk, Kenneth J

Keywords: Emerging Virus; Immune Memory; Immune Response; Model Development; Monkeypox Virus; Mouse; Prairie Dog; Preclinical Models; Vaccine

$100,000

Characterization of monkeypox virus circulation and transmission from wildlife to humans in Africa and identification of wildlife species at elevated risk for infection in Canada

Principal investigatorCIHR2022Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Kindrachuk, Kenneth J; Evans, David H; Forbes, Kristian M; Kelvin, Alyson A

Keywords: Emerging Viruses; Humans; Incidental Hosts; Monkeypox Virus; One Health; Reservoir; Rodents; Surveillance; Wildlife; Zoonosis

$750,000

Understanding mechanisms coronavirus cross-reactivity, immune durability, and pan-coronavirus vaccine protection

Nominated PICIHR2022Project Grant - PA: Pandemic Preparedness and Health Emergencies Research

Principal investigators: Kelvin, Alyson A

Keywords: Antigenic Drift; Antigenic Mapping; B Cell Development; Coronavirus; Cross-Reactive Responses; Host Response; Infection-Reinfection; Pan-Coronavirus Vaccine; Vaccine Development; Variant

$100,000

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

Something wrong or missing on this profile? Suggest a correction

Alyson Kelvin

Research

Latest papers

Latest funding

Case presentation of patients hospitalised with mpox (subclade Ib/2023sh) including children, adolescents, and adults in South Kivu, Democratic Republic of the Congo: an observational cohort study.

MPXV Clade IIb virus infection in mice leads to prolonged viral replication, macrophage infiltration, and decreased spermatogenesis in the testes

MassIVE MSV000100569 - GNPS Pansarbecovirus Fusion Protein Vaccine Candidates

Fusion protein pan-sarbecovirus vaccines elicit broadly protective immune responses targeting Clade 1a, 1b, and 3 sarbecoviruses

Influenza infection of the mammary gland

Inhibitory effects of bioactive molecules against nonstructural protein (NSs) of Rift Valley Fever Virus (RVFv): A molecular modeling study

Partial deletion of the OPG164 (A36R) transmembrane phosphoprotein in monkeypox virus clade Ib/sh2023 disrupts the active region involving Tyr140

MPXV Clade IIb virus infection in mice leads to prolonged viral replication, macrophage infiltration, and decreased spermatogenesis in the testes

Complete Genome Sequencing, Annotation, and Mutational Profiling of the Novel Clade I Human Mpox Virus, Kamituga Strain

Epidemiology, clinical characteristics, and transmission patterns of a novel Mpox (Monkeypox) outbreak in eastern Democratic Republic of the Congo (DRC): an observational, cross-sectional cohort study

Influenza Pathogenesis and the Development of Anticipatory Universal Vaccines for Canadian Pandemic Preparedness

Frequent collaborators

David Kelvin

Darryl Falzarano

Volker Gerdts

Jason Kindrachuk

Graham Plastow

Ghader Manafiazar

Younes Miar

Christopher Richardson

Arinjay Banerjee

Angela Rasmussen

Qiang Liu

Craig McCormick

Steven Machtaler

Calvin Sjaarda

Mark Fenton

Nathalie Grandvaux

Melissa Andrew

Shelly McNeil

Joanne Langley

Melissa Andrew

Kenneth Rockwood

John Pezacki

Melissa Andrew

Peter Hedlin

Richard Hegele

Stephen Ferguson

Andrew Van Kessel