Faculty profile

Nathalie Grandvaux

ResearcherResearch CentreUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Nathalie Grandvaux

Researcher

Research Centre

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
6 publications in the last five years, latest in 2025.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (8 CIHR, 2 NSERC), most recently in 2019.
Supervisor on 2 trainee awards (2 CIHR), most recently in 2022.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Cell Signaling Interferon Virus Cytokines Gene Regulation Inflammatory Response Nadph Oxidase Reactive Oxygen Species

Latest papers

No evidence of direct activation of human neutrophil responses by multivalent prefusion trimeric SARS-CoV-2 Spike protein ex vivo.
PloS one · 2025 · senior author
No Evidence of Direct Activation of Human Neutrophil Responses by Multivalent Prefusion Trimeric SARS-CoV-2 Spike Protein ex vivo.
bioRxiv : the preprint server for biology · 2025 · senior author
Comprehensive proteomic analysis of HCoV-OC43 virions and virus-modulated extracellular vesicles.
Journal of virology · 2024

All 30 publications

Latest funding

Characterization of the landscape of STAT1 regulation by oxidative modification of Cysteines to inspire drug design.
CIHR · 2022 · Supervisor
$67,500
Redox regulation of the antiviral response : role of oxidative post-translational modifications of MAVS.
CIHR · 2019 · Nominated PI
$730,575
Synergism between IFNß and TNFa: non-canonical functions of STAT2 and IRF9 transcription factors
NSERC · 2018 · Principal investigator
$348,000

All 15 grants and awards

30 publications.

No evidence of direct activation of human neutrophil responses by multivalent prefusion trimeric SARS-CoV-2 Spike protein ex vivo.

Fortin A, Huot S, Caron E, Laflamme C, Pagliuzza A, Chomont N, Gilbert C, Zhang B, Kwong PD, Pouliot M, Grandvaux N

PloS one2025Senior author

DOI: 10.1371/journal.pone.0332261 PMID: 41160626

No Evidence of Direct Activation of Human Neutrophil Responses by Multivalent Prefusion Trimeric SARS-CoV-2 Spike Protein ex vivo.

Fortin A, Huot S, Caron E, Laflamme C, Pagliuzza A, Chomont N, Gilbert C, Zhang B, Kwong PD, Pouliot M, Grandvaux N

bioRxiv : the preprint server for biology2025Senior author

DOI: 10.1101/2025.05.08.652856 PMID: 41031024

Comprehensive proteomic analysis of HCoV-OC43 virions and virus-modulated extracellular vesicles.

Joharinia N, Bonneil É, Grandvaux N, Thibault P, Lippé R

Journal of virology2024

DOI: 10.1128/jvi.00850-24 PMID: 38953378

Redox signaling in cell fate: Beyond damage.

Lamontagne F, Paz-Trejo C, Zamorano Cuervo N, Grandvaux N

Biochimica et biophysica acta. Molecular cell research2024Senior author

DOI: 10.1016/j.bbamcr.2024.119722 PMID: 38615720

Detection of viable SARS-CoV-2 in retrospective analysis of aerosol samples collected from hospital rooms of patients with COVID-19.

Fortin A, Veillette M, Larrotta A, Longtin Y, Duchaine C, Grandvaux N

Clinical microbiology and infection : the official publication of the European Society of Clinical Microbiology and Infectious Diseases2023Senior author

DOI: 10.1016/j.cmi.2023.03.019 PMID: 36963565

Redox proteomics and structural analyses provide insightful implications for additional non-catalytic thiol-disulfide motifs in PDIs.

Cuervo NZ, Grandvaux N

Redox biology2023Senior author

DOI: 10.1016/j.redox.2022.102583 PMID: 36567215

Molecular Determinants of SARS-CoV-2 Variants

Banerjee A, Mossman K, Grandvaux N

Trends in Microbiology202140 citationsSenior author

DOI: 10.1016/j.tim.2021.07.002

Ozone inactivation of airborne influenza and lack of resistance of respiratory syncytial virus to aerosolization and sampling processes.

Dubuis ME, Racine É, Vyskocil JM, Turgeon N, Tremblay C, Mukawera E, Boivin G, Grandvaux N, Duchaine C

PloS one2021

DOI: 10.1371/journal.pone.0253022 PMID: 34252093

The Biobanque québécoise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories.

Tremblay K, Rousseau S, Zawati MH, Auld D, Chassé M, Coderre D, Falcone EL, Gauthier N, Grandvaux N, Gros-Louis F, Jabet C, Joly Y, Kaufmann DE, Laprise C, Larochelle C, Maltais F, Mes-Masson AM, Montpetit A, Piché A, Richards JB, Tse SM, Turgeon AF, Turecki G, Vinh DC, Wang HT, Mooser V, BQC19

PloS one2021

DOI: 10.1371/journal.pone.0245031 PMID: 34010280

Pinpointing cysteine oxidation sites by high-resolution proteomics reveals a mechanism of redox-dependent inhibition of human STING.

Zamorano Cuervo N, Fortin A, Caron E, Chartier S, Grandvaux N

Science signaling2021Senior author

DOI: 10.1126/scisignal.aaw4673 PMID: 33906974

Characterization of the landscape of STAT1 regulation by oxidative modification of Cysteines to inspire drug design.

SupervisorCIHR2022Fellowship - PA: Takeda Canada and CIHR Institute of Genetics Rare Diseases

Principal investigators: Paz Trejo, Cynthia A

Keywords: Immunity, Cell Signaling, Redox, Proteomics, Immunodeficienc

$67,500

Redox regulation of the antiviral response : role of oxidative post-translational modifications of MAVS.

Nominated PICIHR2019Project Grant

Principal investigators: Grandvaux, Nathalie

Keywords: Antiviral; Cell Signaling; Interferon; Molecular Modeling; Post-Translational Modifications; Redox; Virus

$730,575

Synergism between IFNß and TNFa: non-canonical functions of STAT2 and IRF9 transcription factors

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Grandvaux, Nathalie

$348,000

Autophagy in the control of RSV replication in human airway epithelial cells

Nominated PICIHR2018Project Grant

Principal investigators: Grandvaux, Nathalie

Keywords: Autophagy; Cellular Signaling; Host-Pathogen Interaction; Secretion; Ubiquitination; Viral Cycle; Virus; Virus Replication; Virus Trafficking

$696,150

Targeting mTOR to restore mucosal immunity toward remission in HIV-infected individuals

Co-investigatorCIHR2017Operating Grant: Innovative Biomedical and Clinical HIV/AIDS Research

Principal investigators: Ancuta, Petronela; Routy, Jean-Pierre

Keywords: Cd4+ T-Cells; Flow Cytometry; Genome-Wide Transcriptional Profiling; Hiv Reservoirs; Hiv-1; Mammalian Target Of Rapamycin; Microscopy; Mucosal Immunity; Rna Interference; Th17 Cells

$250,000

Mucosal innate immunity in HIV resistant women

Co-investigatorCIHR2016Project Grant

Principal investigators: Roger, Michel

Keywords: Dendritic Cells; Female Commercial Sex Workers; Genetic Polymorphisms; Genital Mucosal Immunity; Highly-Exposed Seronegative (Hesn); Hiv/Aids Pathogenesis; Interferon

$573,375

First workshop of the Canadian Society for Virology

Nominated PICIHR2016Planning and Dissemination Grant - Institute Community Support

Principal investigators: Grandvaux, Nathalie; McCormick, Craig

Keywords: Virology

$10,000

Redox regulation of the innate antiviral response in airway epithelial cells: regulation and function of DUOX2.

Nominated PICIHR2014Operating Grant

Principal investigators: Grandvaux, Nathalie

Keywords: Cytokines; Gene Regulation; Inflammatory Response; Nadph Oxidase; Reactive Oxygen Species; Respiratory Virus; Signal Transduction

$593,556

The CRCHUM Symposia on Research Priorities Toward a Cure in Chronic Viral Infectious Diseases: From Pathogen Sensing to Eradication

Co-investigatorCIHR2014Planning and Dissemination Grant - Institute Community Support

Principal investigators: Ancuta, Petronela

Keywords: Cd4+ T Cells; Dendritic Cells; Hcv; Hiv; Hpv; Human; Immune Responses; Pattern Recognition Receptors; Viral Latency; Viral Reservoirs And Eradication

$10,000

Redox regulation of the innate antiviral response in airway epithelial cells: regulation and function of DUOX2.

Nominated PICIHR2013Operating Grant - Priority Announcement: Infection and Immunity (Bridge Funding)

Principal investigators: Grandvaux, Nathalie

Keywords: Gene Regulation; Inflammatory Response; Nadph Oxidase; Reactive Oxygen Species; Respiratory Virus; Signal Transduction

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Nathalie Grandvaux

Research

Latest papers

Latest funding

No evidence of direct activation of human neutrophil responses by multivalent prefusion trimeric SARS-CoV-2 Spike protein ex vivo.

No Evidence of Direct Activation of Human Neutrophil Responses by Multivalent Prefusion Trimeric SARS-CoV-2 Spike Protein ex vivo.

Comprehensive proteomic analysis of HCoV-OC43 virions and virus-modulated extracellular vesicles.

Redox signaling in cell fate: Beyond damage.

Detection of viable SARS-CoV-2 in retrospective analysis of aerosol samples collected from hospital rooms of patients with COVID-19.

Redox proteomics and structural analyses provide insightful implications for additional non-catalytic thiol-disulfide motifs in PDIs.

Molecular Determinants of SARS-CoV-2 Variants

Ozone inactivation of airborne influenza and lack of resistance of respiratory syncytial virus to aerosolization and sampling processes.

The Biobanque qu&#xe9;b&#xe9;coise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories.

Pinpointing cysteine oxidation sites by high-resolution proteomics reveals a mechanism of redox-dependent inhibition of human STING.

Synergism between IFNß and TNFa: non-canonical functions of STAT2 and IRF9 transcription factors

Frequent collaborators

Nicolas Chomont

Jean-Pierre Routy

Nicolas Chomont

Marc Pouliot

Sylvain Meloche

Caroline Gilbert

Simon-Pierre Gravel

Pierre Thibault

Rongtuan Lin

Craig McCormick

Jean-Pierre Routy

Petronela Ancuta

Yann Joly

Catherine Larochelle

Catherine Laprise

Anne Gatignol

Vincent Mooser

Gustavo Turecki

Anne-Marie Mes-Masson

Yves Longtin

Yves Longtin

Arinjay Banerjee

Karen Mossman

Simon Rousseau

Guy Boivin

The Biobanque québécoise de la COVID-19 (BQC19)-A cohort to prospectively study the clinical and biological determinants of COVID-19 clinical trajectories.