Faculty profile

Derrick Gibbings

Back to faculty

Assistant ProfessorCellular and Molecular MedicineUniversity of Ottawa

Derrick Gibbings

Assistant Professor

Cellular and Molecular Medicine

Faculty of Medicine

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
6 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 13 research grants (8 NSERC, 5 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

University Profile Personal Website Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Autophagy Amyotrophic Lateral Sclerosis Rna Extracellular Vesicles Genetics Immune Function Immunity Leprosy

Latest papers

A Rosella-PLIN2 knock-in mouse reveals lipophagy and immunometabolic interplay in atherosclerosis.
Autophagy · 2026
Engineered autophagy receptors administered with extracellular vesicles eliminate pathological Tau and TDP-43.
Nature biomedical engineering · 2026 · senior author
Translation in proximity to forming autophagosomes during sustained autophagy.
Nature communications · 2026 · senior author

All 15 publications

Latest funding

Nanoparticle Tracking Instrument for Study of Extracellular Vesicles and Nanoparticles
NSERC · 2024 · Principal investigator
$150,000
New Mechanisms and Therapeutic Strategies in Amyotrophic Lateral Sclerosis
CIHR · 2022 · Nominated PI
$933,300
A pipeline approach for the rational design of neuronal lineage conversion approaches to treat neurological disorders
SSHRC · 2022 · Co-investigator
$8,000,000

All 14 grants and awards

15 publications.

A Rosella-PLIN2 knock-in mouse reveals lipophagy and immunometabolic interplay in atherosclerosis.

Laval T, Joyce N, Boucher DM, Labrana H, Rochon V, Emerton C, Dharia M, Robichaud S, Lorant V, Nguyen MA, Geoffrion M, Rayner KJ, Gibbings D, Nutter LMJ, Russell RC, Ouimet M

Autophagy2026

DOI: 10.1080/15548627.2026.2674711 PMID: 42163465

Engineered autophagy receptors administered with extracellular vesicles eliminate pathological Tau and TDP-43.

Guo H, Savard A, Manser C, Dutta K, Taylor JA, Rousseaux MWC, Pozzi S, Julien JP, Baird S, Gibbings D

Nature biomedical engineering2026Senior author

DOI: 10.1038/s41551-026-01774-9 PMID: 42649384

Translation in proximity to forming autophagosomes during sustained autophagy.

Xue Y, O'Connor K, Nalbach K, Savard A, King KE, Russell RC, Behrends C, Gibbings D

Nature communications2026Senior author

DOI: 10.1038/s41467-026-71551-4 PMID: 41963349

Oxysterol-binding protein ORP6 regulates lipid metabolism and brain Aβ production.

Kasongo AA, Vijithakumar V, Abd-Elrahman KS, Prabhune R, Gharibeh L, Nadeau R, Robillard I, Spring S, Robichaud S, Asif S, Gibbings D, Moore KJ, Sled JG, Ruiz M, Lavallée-Adam M, Ferguson SSG, Lacoste B, Lagace DC, Ouimet M

Journal of lipid research2025

DOI: 10.1016/j.jlr.2025.100868 PMID: 40716750

The Regulation and Immune Signature of Retrotransposons in Cancer.

Alkailani MI, Gibbings D

Cancers2023Senior author

DOI: 10.3390/cancers15174340 PMID: 37686616

Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.

Wedge ME, Jennings VA, Crupi MJF, Poutou J, Jamieson T, Pelin A, Pugliese G, de Souza CT, Petryk J, Laight BJ, Boileau M, Taha Z, Alluqmani N, McKay HE, Pikor L, Khan ST, Azad T, Rezaei R, Austin B, He X, Mansfield D, Rose E, Brown EEF, Crawford N, Alkayyal A, Surendran A, Singaravelu R, Roy DG, Migneco G, McSweeney B, Cottee ML, Jacobus EJ, Keller BA, Yamaguchi TN, Boutros PC, Geoffrion M, Rayner KJ, Chatterjee A, Auer RC, Diallo JS, Gibbings D, tenOever BR, Melcher A, Bell JC, Ilkow CS

Nature communications2022

DOI: 10.1038/s41467-022-29526-8 PMID: 35393414

A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer.

Alkailani M, Palidwor G, Poulin A, Mohan R, Pepin D, Vanderhyden B, Gibbings D

NAR cancer2021Senior author

DOI: 10.1093/narcan/zcaa040 PMID: 33447827

Wild-type and mutant SOD1 localizes to RNA-rich structures in cells and mice but does not bind RNA.

Da Ros M, Deol HK, Savard A, Guo H, Meiering EM, Gibbings D

Journal of neurochemistry2021Senior author

DOI: 10.1111/jnc.15126 PMID: 32683701

Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone.

Reshke R, Taylor JA, Savard A, Guo H, Rhym LH, Kowalski PS, Trung MT, Campbell C, Little W, Anderson DG, Gibbings D

Nature biomedical engineering2020Senior author

DOI: 10.1038/s41551-019-0502-4 PMID: 31937944

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.

Chitiprolu M, Jagow C, Tremblay V, Bondy-Chorney E, Paris G, Savard A, Palidwor G, Barry FA, Zinman L, Keith J, Rogaeva E, Robertson J, Lavallée-Adam M, Woulfe J, Couture JF, Côté J, Gibbings D

Nature communications2018Senior author

DOI: 10.1038/s41467-018-05273-7 PMID: 30022074

Nanoparticle Tracking Instrument for Study of Extracellular Vesicles and Nanoparticles

Principal investigatorNSERC2024Research Tools and Instruments

Principal investigators: Gibbings, Derrick

Keywords: cell biology; drug delivery; endosomes; exosomes; extracellular vesicles; lipid nanoparticles; nanoparticles; Nanoparticle tracking; particle heterogeneity and subpopulations

$150,000

New Mechanisms and Therapeutic Strategies in Amyotrophic Lateral Sclerosis

Nominated PICIHR2022Project Grant

Principal investigators: Gibbings, Derrick J

Keywords: Amyotrophic Lateral Sclerosis; Autophagy; Extracellular Vesicles; Rna; Stress Granules; Tdp-43

$933,300

A pipeline approach for the rational design of neuronal lineage conversion approaches to treat neurological disorders

Co-investigatorSSHRC2022New Frontiers in Research Fund - Transformation

Principal investigators: Schuurmans, Carol

Keywords: neurodegenerative disease,; Alzheimer's disease; direct neuronal reprogramming; transcription factors; gene regulatory networks ; computer-guided design; nanoparticles; epigenomics ; neurological disorders; self-amplifying RNA; bacteriophage; astrocytes; stroke; epilepsy; focused ultrasound

$8,000,000

Mechanisms of RNA Packaging into Exosomes

Principal investigatorNSERC2019Discovery Grants Program - Accelerator Supplements

Principal investigators: Gibbings, Derrick

$120,000

A platform to deliver silencing RNAs using exosomes

Principal investigatorNSERC2019Collaborative Research and Development Grants

Principal investigators: Gibbings, Derrick

$211,649

Mechanisms of RNA Packaging into Exosomes

Principal investigatorNSERC2019Discovery Grants Program - Individual

Principal investigators: Gibbings, Derrick

$406,000

Packaging of antibodies into exosomes for treatment of neurodegenerative diseases

Principal investigatorNSERC2019Collaborative Research and Development Grants

Principal investigators: Gibbings, Derrick

$240,000

Light Scattering for Nanoscale Analysis of Molecular Machines and Extracellular Vesicles

Principal investigatorNSERC2016Research Tools and Instruments

Principal investigators: Gibbings, Derrick

$149,722

Technology to build a drug delivery platform for silencing RNAs using exosomes

Nominated PICIHR2015Proof of Principle Program - Phase I

Principal investigators: Gibbings, Derrick J

Keywords: Drug Delivery; Exosomes; Extracellular Vesicles; Microrna; Silencing Rna; Sirna

$159,941

Microscopy suite for time-lapse multi-wavelength live cell imaging

Principal investigatorNSERC2015Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Gibbings, Derrick

$150,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

Something wrong or missing on this profile? Suggest a correction

Derrick Gibbings

Research

Latest papers

Latest funding

A Rosella-PLIN2 knock-in mouse reveals lipophagy and immunometabolic interplay in atherosclerosis.

Engineered autophagy receptors administered with extracellular vesicles eliminate pathological Tau and TDP-43.

Translation in proximity to forming autophagosomes during sustained autophagy.

Oxysterol-binding protein ORP6 regulates lipid metabolism and brain Aβ production.

The Regulation and Immune Signature of Retrotransposons in Cancer.

Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.

A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer.

Wild-type and mutant SOD1 localizes to RNA-rich structures in cells and mice but does not bind RNA.

Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone.

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.

Nanoparticle Tracking Instrument for Study of Extracellular Vesicles and Nanoparticles

New Mechanisms and Therapeutic Strategies in Amyotrophic Lateral Sclerosis

A pipeline approach for the rational design of neuronal lineage conversion approaches to treat neurological disorders

Mechanisms of RNA Packaging into Exosomes

A platform to deliver silencing RNAs using exosomes

Mechanisms of RNA Packaging into Exosomes

Packaging of antibodies into exosomes for treatment of neurodegenerative diseases

Light Scattering for Nanoscale Analysis of Molecular Machines and Extracellular Vesicles

Technology to build a drug delivery platform for silencing RNAs using exosomes

Microscopy suite for time-lapse multi-wavelength live cell imaging

Frequent collaborators

Mireille Ouimet

Jean-Pierre Julien

Barbara Vanderhyden

Janice Robertson

John Woulfe

Baptiste Lacoste

Ekaterina Rogaeva

Matthieu Ruiz

Andrew Emili

Silvia Pozzi

Jean-Simon Diallo

Diane Lagace

Rebecca Auer

Derrick Gibbings

Research

Latest papers

Latest funding

A Rosella-PLIN2 knock-in mouse reveals lipophagy and immunometabolic interplay in atherosclerosis.

Engineered autophagy receptors administered with extracellular vesicles eliminate pathological Tau and TDP-43.

Translation in proximity to forming autophagosomes during sustained autophagy.

Oxysterol-binding protein ORP6 regulates lipid metabolism and brain A&#x3b2; production.

The Regulation and Immune Signature of Retrotransposons in Cancer.

Virally programmed extracellular vesicles sensitize cancer cells to oncolytic virus and small molecule therapy.

A genome-wide strategy to identify causes and consequences of retrotransposon expression finds activation by BRCA1 in ovarian cancer.

Wild-type and mutant SOD1 localizes to RNA-rich structures in cells and mice but does not bind RNA.

Reduction of the therapeutic dose of silencing RNA by packaging it in extracellular vesicles via a pre-microRNA backbone.

A complex of C9ORF72 and p62 uses arginine methylation to eliminate stress granules by autophagy.

Nanoparticle Tracking Instrument for Study of Extracellular Vesicles and Nanoparticles

New Mechanisms and Therapeutic Strategies in Amyotrophic Lateral Sclerosis

A pipeline approach for the rational design of neuronal lineage conversion approaches to treat neurological disorders

Mechanisms of RNA Packaging into Exosomes

A platform to deliver silencing RNAs using exosomes

Mechanisms of RNA Packaging into Exosomes

Packaging of antibodies into exosomes for treatment of neurodegenerative diseases

Light Scattering for Nanoscale Analysis of Molecular Machines and Extracellular Vesicles

Technology to build a drug delivery platform for silencing RNAs using exosomes

Microscopy suite for time-lapse multi-wavelength live cell imaging

Frequent collaborators

Mireille Ouimet

Jean-Pierre Julien

Barbara Vanderhyden

Janice Robertson

John Woulfe

Baptiste Lacoste

Ekaterina Rogaeva

Matthieu Ruiz

Andrew Emili

Silvia Pozzi

Jean-Simon Diallo

Diane Lagace

Rebecca Auer

Oxysterol-binding protein ORP6 regulates lipid metabolism and brain Aβ production.