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Jennifer Gommerman

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ProfessorDepartment of ImmunologyUniversity of Toronto

Jennifer Gommerman

Professor

Department of Immunology

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Canada Research Chair in Tissue-Specific Immunity

Scholar ORCID

Supervision signals

Professors usually supervise graduate students in their department's programs.
8 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 22 research grants (21 CIHR, 1 NSERC), most recently in 2026.
Supervised 8 trainees who won CIHR awards, most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Education

Ph.D., Immunology
B.Sc., Immunology

Profiles and links

University Profile Google Scholar iDORCID

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Multiple Sclerosis Microbiome Iga Mucosal Immunity Neurodegeneration Immunology Antibody Dependent Enhancement B Cell Reperotire

Latest papers

Preserved SARS-CoV-2 T-cell responses despite impaired humoral immunity in children with profound B-cell lymphopenia.
NPJ vaccines · 2026
Maintenance of chronic neuroinflammation in multiple sclerosis via interferon signaling and CD8 T-cell-mediated cytotoxicity.
Research square · 2025
Astrocytes ACLYmate to chronic neuroinflammation.
Trends in immunology · 2024 · senior author

All 17 publications

Latest funding

The role of the microbiome in generating a SARS-CoV-2 spike-specific IgA response
CIHR · 2026 · Nominated PI
$1,166,626
Evaluating the impact of an aged hematopoietic system on grey matter injury
CIHR · 2024 · Nominated PI
$16,667
Investigating the impact of mild traumatic brain injury in MS progression
CIHR · 2024 · Supervisor
$210,000

All 41 grants and awards

17 publications.

Preserved SARS-CoV-2 T-cell responses despite impaired humoral immunity in children with profound B-cell lymphopenia.

Nantel S, Sassine S, Bourdin B, Barbosa Da Torre M, Sutton G, Rabezanahary H, Qi F, Ward LA, Delgado-Brand M, Adams K, Sheikh-Mohamed S, Wang L, Nicholson S, Laghdir Z, Colwill K, Chao G, Seifried L, Liu Y, Rini JM, Gommerman J, Gingras AC, Baz M, Zinzser K, Quach C, Decaluwe H

NPJ vaccines2026

DOI: 10.1038/s41541-026-01525-6 PMID: 42477358

Maintenance of chronic neuroinflammation in multiple sclerosis via interferon signaling and CD8 T-cell-mediated cytotoxicity.

Raza SA, Enose-Akahata Y, Blazier A, Guerra LM, Beck ES, Gaítan MI, Ngouth N, Drijvers JM, Dammer EB, Moodley D, Johnson KR, Absinta M, Ramaglia V, Gommerman J, Turner TJ, Ransohoff RM, Jacobson S, Ofengeim D, Cahir-McFarland E, Reich DS

Research square2025

DOI: 10.21203/rs.3.rs-7633686/v1 PMID: 41041547

Astrocytes ACLYmate to chronic neuroinflammation.

Champagne-Jorgensen K, Gommerman J

Trends in immunology2024Senior author

DOI: 10.1016/j.it.2024.04.003 PMID: 38632002

Comparable safety and non-inferior immunogenicity of the SARS-CoV-2 mRNA vaccine candidate PTX-COVID19-B and BNT162b2 in a phase 2 randomized, observer-blinded study.

Reiter L, Greffrath J, Zidel B, Ostrowski M, Gommerman J, Madhi SA, Tran R, Martin-Orozco N, Panicker RKG, Cooper C, Pastrak A

Scientific reports2024

DOI: 10.1038/s41598-024-55320-1 PMID: 38438427

Immunogenicity of COVID-19 vaccines and their effect on HIV reservoir in older people with HIV.

Matveev VA, Mihelic EZ, Benko E, Budylowski P, Grocott S, Lee T, Korosec CS, Colwill K, Stephenson H, Law R, Ward LA, Sheikh-Mohamed S, Mailhot G, Delgado-Brand M, Pasculescu A, Wang JH, Qi F, Tursun T, Kardava L, Chau S, Samaan P, Imran A, Copertino DC, Chao G, Choi Y, Reinhard RJ, Kaul R, Heffernan JM, Jones RB, Chun TW, Moir S, Singer J, Gommerman J, Gingras AC, Kovacs C, Ostrowski M

iScience2023

DOI: 10.1016/j.isci.2023.107915 PMID: 37790281

Cross-talk between B cells, microglia and macrophages, and implications to central nervous system compartmentalized inflammation and progressive multiple sclerosis.

Touil H, Li R, Zuroff L, Moore CS, Healy L, Cignarella F, Piccio L, Ludwin S, Prat A, Gommerman J, Bennett FC, Jacobs D, Benjamins JA, Lisak RP, Antel JP, Bar-Or A

EBioMedicine2023

DOI: 10.1016/j.ebiom.2023.104789 PMID: 37703640

Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV.

bioRxiv : the preprint server for biology2023

DOI: 10.1101/2023.06.14.544834 PMID: 37502977

Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control.

Swanson RV, Gupta A, Foreman TW, Lu L, Choreno-Parra JA, Mbandi SK, Rosa BA, Akter S, Das S, Ahmed M, Garcia-Hernandez ML, Singh DK, Esaulova E, Artyomov MN, Gommerman J, Mehra S, Zuniga J, Mitreva M, Scriba TJ, Rangel-Moreno J, Kaushal D, Khader SA

Nature immunology2023

DOI: 10.1038/s41590-023-01476-3 PMID: 37012543

Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity.

Perez-Shibayama C, Gil-Cruz C, Cheng HW, Onder L, Printz A, Mörbe U, Novkovic M, Li C, Lopez-Macias C, Buechler MB, Turley SJ, Mack M, Soneson C, Robinson MD, Scandella E, Gommerman J, Ludewig B

Science immunology2018

DOI: 10.1126/sciimmunol.aar4539 PMID: 30097537

Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis.

Touil H, Kobert A, Lebeurrier N, Rieger A, Saikali P, Lambert C, Fawaz L, Moore CS, Prat A, Gommerman J, Antel JP, Itoyama Y, Nakashima I, Bar-Or A, Canadian B Cell Team in MS

Journal of neuroinflammation2018

DOI: 10.1186/s12974-018-1136-2 PMID: 29673365

The role of the microbiome in generating a SARS-CoV-2 spike-specific IgA response

Nominated PICIHR2026Project Grant

Principal investigators: Gommerman, Jennifer L

Keywords: Iga; Immune Response; Microbiome; Mrna Vaccines; Sars-Cov-2

$1,166,626

Evaluating the impact of an aged hematopoietic system on grey matter injury

Nominated PICIHR2024PRIZE - Pro. Gr. - PA: Yves Joanette Award of Excellence in Research in Aging

Principal investigators: Gommerman, Jennifer L

Keywords: Age-Dependent Brain Disease; Aging Immune System; Multiple Sclerosis; Neurodegeneration

$16,667

Investigating the impact of mild traumatic brain injury in MS progression

SupervisorCIHR2024CIHR Fellowship

Principal investigators: Enterina, Jhon Ralph D

Keywords: B Lymphocytes; Glia Limitans Superficialis; Grey Matter; Microglia; Multiple Sclerosis; Neuroimmunology; Progressive Multiple Sclerosis; Stromal Cells; Tertiary Lymphoid Tissues; Traumatic Brain Injury

$210,000

Evaluating the impact of concussion on meningeal integrity and grey matter resilience

Nominated PICIHR2024Project Grant

Principal investigators: Gommerman, Jennifer L

Keywords: Experimental Autoimmune Encephalomyelitis; Meninges; Mild Traumatic Brain Injury; Multiple Sclerosis

$1,128,376

Evaluating the impact of an aged hematopoietic system on grey matter injury

Nominated PICIHR2024Project Grant

Principal investigators: Gommerman, Jennifer L

Keywords: Age-Dependent Brain Disease; Aging Immune System; Multiple Sclerosis; Neurodegeneration

$1,180,970

Defining mechanisms of T cell help for pathogen-specific IgA responses at mucosal surfaces

Nominated PICIHR2024Project Grant

Principal investigators: Gommerman, Jennifer L

Keywords: Iga; Igg; Mucosal Immunity; Rotavirus; Sars-Cov-2; T Follicular Helper Cells

$1,128,376

Mechanistic investigations of the innate immune response to cancer cell death and immune tolerance to solid tumor antigens.

Co-investigatorCIHR2024Project Grant

Principal investigators: McGaha, Tracy

Keywords: Chemotherapy; Cytokines; Macrophage; Tumor Immunology

$1,216,350

Manipulating the Microbiome to Prevent Multiple Sclerosis Progression

SupervisorCIHR2023CIHR Fellowship

Principal investigators: Champagne-Jorgensen, Kevin

Keywords: Bacteriophage; Cerebrospinal Fluid; Extracellular Vesicles; Fecal Microbiome Transplant; Microbiome; Microbiota-Gut-Brain Axis; Multiple Sclerosis; Neuroimmunology; Progressive Multiple Sclerosis; Proteomics

$135,000

Long COVID Web: Pan-Canadian Post-COVID Condition Research Network

Principal investigatorCIHR2022Operating Grant: Canadian Post COVID-19 Condition Research Network

Principal investigators: Cheung, Angela M; Goulding, Susie E; Graves, Donna Lorraine; Archambault, Patrick; Awadalla, Philip; Bakal, Jeffrey A; Bhéreur, Anne; Brotto, Lori Anne; Busse, Jason W; Cameron, Jill I; Churchill, Katie; Crawley, Angela M; Décary, Simon; Durand, Madeleine; Falcone, Emilia L; Fowler, Robert A; Gommerman, Jennifer L; Graham, Kathryn E; Graham, Simon J; Groot, Gary; Gross, Douglas P; Guyatt, Gordon H; Halas, Gayle; Ho, Chester; Hohl, Corinne M; Holroyd, Brian R; Janjua, Naveed Z; Johnson, Pauline; Juando Prats, Clara; Kashuba, Sherri; Katz, Alan; Kho, Michelle E; Lam, Grace Y; Lamontagne, Francois; Langlois, Marc-Andre; Lavis, John N; Law, Susan K; LeBlanc, Annie; Levin, Adeera; Liu-Ambrose, Teresa Y; Liu, Peter P; Lix, Lisa M; Mandhane, Piush; Mann, Balraj; McGrail, Kimberlyn M; McNagny, Kelly M; Miciak, Maxi A; Mishra, Sharmistha; Muhajarine, Nazeem; Mukherjee, Manali; Mushquash, Christopher J; Nacul, Luis; O'Brien, Kelly K; Osgood, Nathaniel D; Papathanasoglou, Elisavet; Penninger, Josef; Piche, Alain; Pinto, Andrew D; Quinn, Kieran L; Rafferty, Ellen; Raj, Satish R; Razak, Fahad; Russell, James A; Sander, Beate H; Sekuler, Allison B; Soares, Claudio D; Tailfeathers, Esther; Tomlinson, George A; Tricco, Andrea C; Valdez, Yanet; Verma, Amol; Vohra, Sunita; Walmsley, Sharon L; Walsh, Jillian; Weeks, Laura C; Williams, Kienan; Wu, Jianhong; Yeung, Rae S

Keywords: Biobanking; Knowledge Translation; Long Covid; Mechanism Of Disease; National Network; Patient Engagement; Patient Registries; Post-Covid Condition; Research Communications; Social Determinants Of Health

$19,999,614

COVID-19 Variant Network - Towards a comprehensive understanding of adaptive immunity to SARS-CoV-2

Principal investigatorCIHR2021Operating Grant: SARS-CoV-2 variants supplement stream 2

Principal investigators: Watts, Tania H; Ehrhardt, Rudolf A; Gommerman, Jennifer L; Martin, Alberto; Ostrowski, Mario A

Keywords: Antibody Dependent Enhancement; B Cell Reperotire; Correlates Of Protection; Covid19; Immune Memory; Neutralizing Antibody; Rna-Seq; Saliva Iga; T Cell Epitopes; Vaccines

$100,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Jennifer Gommerman

Research

Latest papers

Latest funding

Preserved SARS-CoV-2 T-cell responses despite impaired humoral immunity in children with profound B-cell lymphopenia.

Maintenance of chronic neuroinflammation in multiple sclerosis via interferon signaling and CD8 T-cell-mediated cytotoxicity.

Astrocytes ACLYmate to chronic neuroinflammation.

Comparable safety and non-inferior immunogenicity of the SARS-CoV-2 mRNA vaccine candidate PTX-COVID19-B and BNT162b2 in a phase 2 randomized, observer-blinded study.

Immunogenicity of COVID-19 vaccines and their effect on HIV reservoir in older people with HIV.

Cross-talk between B cells, microglia and macrophages, and implications to central nervous system compartmentalized inflammation and progressive multiple sclerosis.

Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV.

Antigen-specific B cells direct T follicular-like helper cells into lymphoid follicles to mediate Mycobacterium tuberculosis control.

Fibroblastic reticular cells initiate immune responses in visceral adipose tissues and secure peritoneal immunity.

Human central nervous system astrocytes support survival and activation of B cells: implications for MS pathogenesis.

The role of the microbiome in generating a SARS-CoV-2 spike-specific IgA response

Evaluating the impact of an aged hematopoietic system on grey matter injury

Investigating the impact of mild traumatic brain injury in MS progression

Evaluating the impact of concussion on meningeal integrity and grey matter resilience

Evaluating the impact of an aged hematopoietic system on grey matter injury

Defining mechanisms of T cell help for pathogen-specific IgA responses at mucosal surfaces

Mechanistic investigations of the innate immune response to cancer cell death and immune tolerance to solid tumor antigens.

Manipulating the Microbiome to Prevent Multiple Sclerosis Progression

Long COVID Web: Pan-Canadian Post-COVID Condition Research Network

COVID-19 Variant Network - Towards a comprehensive understanding of adaptive immunity to SARS-CoV-2

Frequent collaborators

Mario Ostrowski

Anne-Claude Gingras

Rupert Kaul

Amit Bar-Or

Alexandre Prat

Li Zhang

Sonya MacParland

Agata Bartczak

Valeria Ramaglia

Jun Liu

Caroline Quach

Robert Rottapel

Curtis Cooper

Mark Cattral

Jack Antel