Faculty profile
Lori Frappier
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Read how they describe their research on their University of Toronto profile.
Latest papers
Locus-specific proteomics identifies novel regulators of Epstein-Barr virus lytic reactivation.
Journal of virology · 2026
Identification of Epstein-Barr virus BORF2 sequences required for APOBEC3B relocalization.
Journal of virology · 2025 · senior author
Profiling miRNA changes in Epstein-Barr virus lytic infection identifies a function for BZLF1 in upregulating miRNAs from the DLK1-DIO3 locus.
PLoS pathogens · 2025 · senior author
Latest funding
- $120,000
Interplay between the stem cell factor SALL4 and Epstein-Barr virus infection
CIHR · 2025 · Supervisor
- $841,500
Regulation and Functions of the Epstein-Barr Virus Lytic Switch Protein
CIHR · 2023 · Nominated PI
- $933,300
Novel Mechanisms of Subversion of Host Processes by Epstein-Barr Virus Proteins
CIHR · 2022 · Nominated PI
80 publications.
Locus-specific proteomics identifies novel regulators of Epstein-Barr virus lytic reactivation.
Greaves DE, Gabaev I, Williamson JC, Bloor S, Martinez Cuesta S, Matheson NJ, Frappier L, Déjardin J, Lehner PJ
Identification of Epstein-Barr virus BORF2 sequences required for APOBEC3B relocalization.
Clark F, Carpenter MA, Harris RS, Frappier L
Profiling miRNA changes in Epstein-Barr virus lytic infection identifies a function for BZLF1 in upregulating miRNAs from the DLK1-DIO3 locus.
Campbell AM, Taylor VC, Cohan B, Frappier L
The human cytomegalovirus-encoded pUS28 antagonizes CD4+ T cell recognition by targeting CIITA.
Maassen F, Le-Trilling VTK, Betke L, Bracht T, Siegmund C, Bayer M, Katschinski B, Belter A, Becker T, Mennerich D, Voigt S, Frappier L, Sitek B, Fleischhauer K, Trilling M
EBNA1.
Frappier L
Changes in SUMO-modified proteins in Epstein-Barr virus infection identifies reciprocal regulation of TRIM24/28/33 complexes and the lytic switch BZLF1.
De La Cruz-Herrera CF, Tatham MH, Siddiqi UZ, Shire K, Marcon E, Greenblatt JF, Hay RT, Frappier L
Virology under the Microscope-a Call for Rational Discourse.
Goodrum F, Lowen AC, Lakdawala S, Alwine J, Casadevall A, Imperiale MJ, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, Boon A, Boulant S, Brandt C, Broadbent A, Brooke C, Cameron C, Campos S, Caposio P, Chan G, Cliffe A, Coffin J, Collins K, Damania B, Daugherty M, Debbink K, DeCaprio J, Dermody T, Dikeakos J, DiMaio D, Dinglasan R, Duprex WP, Dutch R, Elde N, Emerman M, Enquist L, Fane B, Fernandez-Sesma A, Flenniken M, Frappier L, Frieman M, Frueh K, Gack M, Gaglia M, Gallagher T, Galloway D, García-Sastre A, Geballe A, Glaunsinger B, Goff S, Greninger A, Hancock M, Harris E, Heaton N, Heise M, Heldwein E, Hogue B, Horner S, Hutchinson E, Hyser J, Jackson W, Kalejta R, Kamil J, Karst S, Kirchhoff F, Knipe D, Kowalik T, Lagunoff M, Laimins L, Langlois R, Lauring A, Lee B, Leib D, Liu SL, Longnecker R, Lopez C, Luftig M, Lund J, Manicassamy B, McFadden G, McIntosh M, Mehle A, Miller WA, Mohr I, Moody C, Moorman N, Moscona A, Mounce B, Munger J, Münger K, Murphy E, Naghavi M, Nelson J, Neufeldt C, Nikolich J, O'Connor C, Ono A, Orenstein W, Ornelles D, Ou JH, Parker J, Parrish C, Pekosz A, Pellett P, Pfeiffer J, Plemper R, Polyak S, Purdy J, Pyeon D, Quinones-Mateu M, Renne R, Rice C, Schoggins J, Roller R, Russell C, Sandri-Goldin R, Sapp M, Schang L, Schmid S, Schultz-Cherry S, Semler B, Shenk T, Silvestri G, Simon V, Smith G, Smith J, Spindler K, Stanifer M, Subbarao K, Sundquist W, Suthar M, Sutton T, Tai A, Tarakanova V, tenOever B, Tibbetts S, Tompkins S, Toth Z, van Doorslaer K, Vignuzzi M, Wallace N, Walsh D, Weekes M, Weinberg J, Weitzman M, Weller S, Whelan S, White E, Williams B, Wobus C, Wong S, Yurochko A
Virology under the Microscope-a Call for Rational Discourse.
Goodrum F, Lowen AC, Lakdawala S, Alwine J, Casadevall A, Imperiale MJ, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, Boon A, Boulant S, Brandt C, Broadbent A, Brooke C, Cameron C, Campos S, Caposio P, Chan G, Cliffe A, Coffin J, Collins K, Damania B, Daugherty M, Debbink K, DeCaprio J, Dermody T, Dikeakos J, DiMaio D, Dinglasan R, Duprex WP, Dutch R, Elde N, Emerman M, Enquist L, Fane B, Fernandez-Sesma A, Flenniken M, Frappier L, Frieman M, Frueh K, Gack M, Gaglia M, Gallagher T, Galloway D, García-Sastre A, Geballe A, Glaunsinger B, Goff S, Greninger A, Hancock M, Harris E, Heaton N, Heise M, Heldwein E, Hogue B, Horner S, Hutchinson E, Hyser J, Jackson W, Kalejta R, Kamil J, Karst S, Kirchhoff F, Knipe D, Kowalik T, Lagunoff M, Laimins L, Langlois R, Lauring A, Lee B, Leib D, Liu SL, Longnecker R, Lopez C, Luftig M, Lund J, Manicassamy B, McFadden G, McIntosh M, Mehle A, Miller WA, Mohr I, Moody C, Moorman N, Moscona A, Mounce B, Munger J, Münger K, Murphy E, Naghavi M, Nelson J, Neufeldt C, Nikolich J, O'Connor C, Ono A, Orenstein W, Ornelles D, Ou JH, Parker J, Parrish C, Pekosz A, Pellett P, Pfeiffer J, Plemper R, Polyak S, Purdy J, Pyeon D, Quinones-Mateu M, Renne R, Rice C, Schoggins J, Roller R, Russell C, Sandri-Goldin R, Sapp M, Schang L, Schmid S, Schultz-Cherry S, Semler B, Shenk T, Silvestri G, Simon V, Smith G, Smith J, Spindler K, Stanifer M, Subbarao K, Sundquist W, Suthar M, Sutton T, Tai A, Tarakanova V, tenOever B, Tibbetts S, Tompkins S, Toth Z, van Doorslaer K, Vignuzzi M, Wallace N, Walsh D, Weekes M, Weinberg J, Weitzman M, Weller S, Whelan S, White E, Williams B, Wobus C, Wong S, Yurochko A
Virology under the Microscope-a Call for Rational Discourse.
Goodrum F, Lowen AC, Lakdawala S, Alwine J, Casadevall A, Imperiale MJ, Atwood W, Avgousti D, Baines J, Banfield B, Banks L, Bhaduri-McIntosh S, Bhattacharya D, Blanco-Melo D, Bloom D, Boon A, Boulant S, Brandt C, Broadbent A, Brooke C, Cameron C, Campos S, Caposio P, Chan G, Cliffe A, Coffin J, Collins K, Damania B, Daugherty M, Debbink K, DeCaprio J, Dermody T, Dikeakos J, DiMaio D, Dinglasan R, Duprex WP, Dutch R, Elde N, Emerman M, Enquist L, Fane B, Fernandez-Sesma A, Flenniken M, Frappier L, Frieman M, Frueh K, Gack M, Gaglia M, Gallagher T, Galloway D, García-Sastre A, Geballe A, Glaunsinger B, Goff S, Greninger A, Hancock M, Harris E, Heaton N, Heise M, Heldwein E, Hogue B, Horner S, Hutchinson E, Hyser J, Jackson W, Kalejta R, Kamil J, Karst S, Kirchhoff F, Knipe D, Kowalik T, Lagunoff M, Laimins L, Langlois R, Lauring A, Lee B, Leib D, Liu SL, Longnecker R, Lopez C, Luftig M, Lund J, Manicassamy B, McFadden G, McIntosh M, Mehle A, Miller WA, Mohr I, Moody C, Moorman N, Moscona A, Mounce B, Munger J, Münger K, Murphy E, Naghavi M, Nelson J, Neufeldt C, Nikolich J, O'Connor C, Ono A, Orenstein W, Ornelles D, Ou JH, Parker J, Parrish C, Pekosz A, Pellett P, Pfeiffer J, Plemper R, Polyak S, Purdy J, Pyeon D, Quinones-Mateu M, Renne R, Rice C, Schoggins J, Roller R, Russell C, Sandri-Goldin R, Sapp M, Schang L, Schmid S, Schultz-Cherry S, Semler B, Shenk T, Silvestri G, Simon V, Smith G, Smith J, Spindler K, Stanifer M, Subbarao K, Sundquist W, Suthar M, Sutton T, Tai A, Tarakanova V, tenOever B, Tibbetts S, Tompkins S, Toth Z, van Doorslaer K, Vignuzzi M, Wallace N, Walsh D, Weekes M, Weinberg J, Weitzman M, Weller S, Whelan S, White E, Williams B, Wobus C, Wong S, Yurochko A
G1/S Cell Cycle Induction by Epstein-Barr Virus BORF2 Is Mediated by P53 and APOBEC3B.
Yockteng-Melgar J, Shire K, Cheng AZ, Malik-Soni N, Harris RS, Frappier L
Interplay between the stem cell factor SALL4 and Epstein-Barr virus infection
Principal investigators: Taylor, Victoria C
Keywords: Chip-Qpcr; Epstein-Barr Virus; Gastric Carcinoma; Luciferase Assay; Lytic Infection; Nasopharyngeal Carcinoma; Oncogenesis; Rt-Qpcr; Stem Cell Factor; Western Blot
Regulation and Functions of the Epstein-Barr Virus Lytic Switch Protein
Principal investigators: Frappier, Lori D
Keywords: Mirna; Protein Function; Sall4; Transcriptional Regulation; Trim Proteins
Novel Mechanisms of Subversion of Host Processes by Epstein-Barr Virus Proteins
Principal investigators: Frappier, Lori D
Keywords: Apobec3b; Gigyf2; Mirna; Protein-Protein Interactions; Proteomics; Risc; Rna-Seq
SUMO-Modulating Proteins of Epstein-Barr Virus
Principal investigators: Frappier, Lori D
Keywords: Bmrf1; Brlf1; Epstein-Barr Virus; Sm; Sumo Ligase; Sumoylation
Functions and Mechanisms of Epstein-Barr Virus SUMO-modulating proteins
Principal investigators: de la Cruz Herrera, Carlos F
Keywords: Cellular Regulation; Herpesvirus-Host Interactions; Sumo Pathway
Using Herpesvirus Proteomics to Identify Mechanisms of Cellular Regulation
Principal investigators: Frappier, Lori D
Keywords: Affinity Purification-Mass Spectroscopy; Cytomegalovirus; Epstein-Barr Virus; Herpes Simplex Virus; Protein Interactions
Mechanisms of Regulation of PML Nuclear Bodies
Principal investigators: Frappier, Lori D
Keywords: Affinity Purification-Mass Spectroscopy; Promyelocytic Leukemia Nuclear Bodies; Protein Interactions; Rnf168; Scf Complex; Ubiquitin Ligase
Mechanisms of EBNA1 disruption of PML nuclear bodies
Principal investigators: Özcelik, Dennis
Keywords: Cell Biology And Viral Infection
Mechanisms of Epstein-Barr Virus Persistence
Principal investigators: Frappier, Lori D
Keywords: Cell Cycle; Dna Damage Response; Ebna1; Epstein-Barr Virus; Lytic Reactivation; Microrna; Proteomics
CANADA RESEARCH CHAIRHOLDER - TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA
Principal investigators: Frappier, Lori D
Keywords: Crc
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Department of Molecular Genetics
- Donnelly Centre
- Biomedical and Molecular Sciences
- PATHOLOGY & LABORATORY MEDICINE, Western University
- Research Institute
- Radiation Oncology
- Banting and Best Department of Medical Research
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Jack Greenblatt
Donnelly Centre
11 shared papers, latest 2022
Miguel Quinones-Mateu
PATHOLOGY & LABORATORY MEDICINE, Western University
3 shared papers, latest 2023
Bruce Banfield
Biomedical and Molecular Sciences
3 shared papers, latest 2023
Brian Raught
Research Institute
2 shared papers, latest 2019
Amélie Fradet-Turcotte
Faculty
2 shared papers, latest 2019
Fei-Fei Liu
Radiation Oncology
2 shared papers, latest 2012
John Kim
Neuropsychology
1 shared papers, latest 2007
David Johnson
Faculty
1 shared papers, latest 2005
Andrew Emili
Banting and Best Department of Medical Research
1 shared papers, latest 2015
Alan Cochrane
Department of Molecular Genetics
1 shared papers, latest 2009
Jason Moffat
Genetics and Genome Biology
1 shared papers, latest 2016
Anne-Claude Gingras
Department of Molecular Genetics
1 shared papers, latest 2015
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Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.