Faculty profile
Myron Cybulsky
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Latest papers
The Endothelium as a Hub for Cellular Communication in Atherogenesis: Is There Directionality to the Message?
Frontiers in cardiovascular medicine · 2022
Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.
Communications biology · 2022
Prospective observational study and serosurvey of SARS-CoV-2 infection in asymptomatic healthcare workers at a Canadian tertiary care center.
PloS one · 2021
Latest funding
- $1,400,000
Canada Research Chair - Tier 1
CIHR · 2021 · Nominated PI
- $776,476
Mechanisms of Arterial Stiffening in Calcification
CIHR · 2020 · Co-investigator
- $90,000
Discerning cell types and intercellular communication in the normal and atherosclerotic mouse artery intima.
CIHR · 2020 · Supervisor
7 publications.
The Endothelium as a Hub for Cellular Communication in Atherogenesis: Is There Directionality to the Message?
Howe KL, Cybulsky M, Fish JE
Macrophage Jak2 deficiency accelerates atherosclerosis through defects in cholesterol efflux.
Dotan I, Yang J, Ikeda J, Roth Z, Pollock-Tahiri E, Desai H, Sivasubramaniyam T, Rehal S, Rapps J, Li YZ, Le H, Farber G, Alchami E, Xiao C, Karim S, Gronda M, Saikali MF, Tirosh A, Wagner KU, Genest J, Schimmer AD, Gupta V, Minden MD, Cummins CL, Lewis GF, Robbins C, Jongstra-Bilen J, Cybulsky M, Woo M
Prospective observational study and serosurvey of SARS-CoV-2 infection in asymptomatic healthcare workers at a Canadian tertiary care center.
Ferreira VH, Chruscinski A, Kulasingam V, Pugh TJ, Dus T, Wouters B, Oza A, Ierullo M, Ku T, Majchrzak-Kita B, Humar ST, Bahinskaya I, Pinzon N, Zhang J, Heisler LE, Krzyzanowski PM, Lam B, Lungu IM, Manase D, Pace KM, Mashouri P, Brudno M, Garrels M, Mazzulli T, Cybulsky M, Humar A, Kumar D
A Hematogenous Route for Medulloblastoma Leptomeningeal Metastases.
Garzia L, Kijima N, Morrissy AS, De Antonellis P, Guerreiro-Stucklin A, Holgado BL, Wu X, Wang X, Parsons M, Zayne K, Manno A, Kuzan-Fischer C, Nor C, Donovan LK, Liu J, Qin L, Garancher A, Liu KW, Mansouri S, Luu B, Thompson YY, Ramaswamy V, Peacock J, Farooq H, Skowron P, Shih DJH, Li A, Ensan S, Robbins CS, Cybulsky M, Mitra S, Ma Y, Moore R, Mungall A, Cho YJ, Weiss WA, Chan JA, Hawkins CE, Massimino M, Jabado N, Zapotocky M, Sumerauer D, Bouffet E, Dirks P, Tabori U, Sorensen PHB, Brastianos PK, Aldape K, Jones SJM, Marra MA, Woodgett JR, Wechsler-Reya RJ, Fults DW, Taylor MD
A CD103+ Conventional Dendritic Cell Surveillance System Prevents Development of Overt Heart Failure during Subclinical Viral Myocarditis.
Clemente-Casares X, Hosseinzadeh S, Barbu I, Dick SA, Macklin JA, Wang Y, Momen A, Kantores C, Aronoff L, Farno M, Lucas TM, Avery J, Zarrin-Khat D, Elsaesser HJ, Razani B, Lavine KJ, Husain M, Brooks DG, Robbins CS, Cybulsky M, Epelman S
GEF-H1 is necessary for neutrophil shear stress-induced migration during inflammation.
Fine N, Dimitriou ID, Rullo J, Sandí MJ, Petri B, Haitsma J, Ibrahim H, La Rose J, Glogauer M, Kubes P, Cybulsky M, Rottapel R
Identification of the receptor for FGL2 and implications for susceptibility to mouse hepatitis virus (MHV-3)-induced fulminant hepatitis.
Liu H, Zhang L, Cybulsky M, Gorczynski R, Crookshank J, Manuel J, Grant D, Levy G
Canada Research Chair - Tier 1
Principal investigators: Cybulsky, Myron I
Keywords: Crc
Mechanisms of Arterial Stiffening in Calcification
Principal investigators: Bendeck, Michelle P
Keywords: Atherosclerosis; Calcification; Discoidin Domain Receptor; Extracellular Matrix; Human Tissue; Mechanotransduction; Mouse Models Of Disease; Smooth Muscle Cells; Transgenic Mice; Vascular Stiffening
Discerning cell types and intercellular communication in the normal and atherosclerotic mouse artery intima.
Principal investigators: Scipione, Corey A
Keywords: Aortic Intima; Atherosclerosis; Bioinformatics; Endothelial; Hypercholesterolemia; Leukocyte; Lipid Metabolism; Method Development; Single Cell Sequencing; Transgenic Mouse Models
The Role of Sphingosine-1-Phosphate in the Reverse Transendothelial Migration of Intimal Myeloid Cells
Principal investigators: Polenz, Chanele
Keywords: Ics Travel Awards
Single cell transcriptomic analysis of the mouse aortic intima: Insights into intercellular communication during early atherogenesis
Principal investigators: Scipione, Corey A
Keywords: Atherogenesis; Atherosclerosis; Endothelial Cells; Hypercholesterolemia; Ics Travel Awards; Intercellular Communication; Mouse Model; Myeloid Cells; Single Cell Rna Sequencing; Transcriptomics
Lipid loading of macrophages suppresses LPS-induced inflammatory gene expression by negatively regulating HIF1a-dependent glycolysis
Principal investigators: Ting, Kenneth K
Keywords: Ics Travel Awards
Cellular and molecular mechanisms regulating the progression of atherosclerosis: exploiting macrophage reverse transendothelial migration as a therapeutic strategy
Principal investigators: Cybulsky, Myron I
Keywords: Atherosclerosis; Cell Migration; Dendritic Cells; Endothelial Cells; Inflammation; Intima; Macrophages; Monocytes; Signalling; Transgenic Mouse Models
Functional and evolutionary dissection of vascular endothelial cell responses to Inflammation
Principal investigators: Wilson, Michael D; Fish, Jason E
Keywords: Atherosclerosis; Comparative Genomics; Endothelial Cells; Epigenetics; Evolution; Functional Genomics; Gene Regulation; Genome Biology; Inflammation; Transcriptional Control
Regenerative biomaterials in vascularized tissue engineering
Principal investigators: Sefton, Michael V
Keywords: Biomaterials; Endothelial Cells; Host Response; Macrophage; Tissue Engineering; Vascularization
Inflammatory functions of lipid-laden macrophages in early atherosclerosis.
Principal investigators: Cybulsky, Myron I
Keywords: Alpha-4 Integrins; Atherosclerosis; Chemokines/Receptors; Dendritic Cells; Endothelium; Inflammation; Macrophage Foam Cells; Monocyte Recruitment; Nf-Kappab; Transgenic/Knockout Mice; Vcam-1
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Uri Tabori and Eric Bouffet: 117 shared papers
- Vijay Ramaswamy and Eric Bouffet: 107 shared papers
- Atul Humar and Deepali Kumar: 99 shared papers
- Uri Tabori and Vijay Ramaswamy: 80 shared papers
- Nada Jabado and Vijay Ramaswamy: 37 shared papers
- Nada Jabado and Eric Bouffet: 34 shared papers
- Uri Tabori and Nada Jabado: 26 shared papers
- Vijay Ramaswamy and Livia Garzia: 15 shared papers
- Vathany Kulasingam and Deepali Kumar: 12 shared papers
- Vathany Kulasingam and Atul Humar: 11 shared papers
- Eric Bouffet and Livia Garzia: 11 shared papers
- Uri Tabori and Livia Garzia: 9 shared papers
- Kenneth Aldape and Vijay Ramaswamy: 6 shared papers
- Tony Mazzulli and Atul Humar: 6 shared papers
- Uri Tabori and Michael Brudno: 5 shared papers
- Uri Tabori and Kenneth Aldape: 5 shared papers
- Mansoor Husain and Slava Epelman: 5 shared papers
- Michael Brudno and Eric Bouffet: 5 shared papers
- Tony Mazzulli and Deepali Kumar: 5 shared papers
- Slava Epelman and Yiming Wang: 4 shared papers
- Kenneth Aldape and Eric Bouffet: 4 shared papers
- Andrzej Chruscinski and Atul Humar: 4 shared papers
- Nada Jabado and Michael Brudno: 3 shared papers
- Vathany Kulasingam and Andrzej Chruscinski: 3 shared papers
- Vathany Kulasingam and Tony Mazzulli: 3 shared papers
- Michael Glogauer and Robert Rottapel: 2 shared papers
- Mansoor Husain and Minna Woo: 2 shared papers
- Mansoor Husain and Yiming Wang: 2 shared papers
- Minna Woo and Jacques Genest: 2 shared papers
- Michael Brudno and Amit Oza: 2 shared papers
- Andrzej Chruscinski and Deepali Kumar: 2 shared papers
- Uri Tabori and Myron Cybulsky: 1 shared paper
- Michael Glogauer and Minna Woo: 1 shared paper
- Michael Glogauer and Paul Kubes: 1 shared paper
- Michael Glogauer and Myron Cybulsky: 1 shared paper
- Robert Rottapel and Paul Kubes: 1 shared paper
- Robert Rottapel and Myron Cybulsky: 1 shared paper
- Robert Rottapel and Amit Oza: 1 shared paper
- Mansoor Husain and Myron Cybulsky: 1 shared paper
- Minna Woo and Myron Cybulsky: 1 shared paper
- Minna Woo and Clinton Robbins: 1 shared paper
- Nada Jabado and Myron Cybulsky: 1 shared paper
- Michael Brudno and Myron Cybulsky: 1 shared paper
- Paul Kubes and Myron Cybulsky: 1 shared paper
- Myron Cybulsky and Clinton Robbins: 1 shared paper
- Myron Cybulsky and Li Zhang: 1 shared paper
- Myron Cybulsky and Slava Epelman: 1 shared paper
- Myron Cybulsky and Kenneth Aldape: 1 shared paper
- Myron Cybulsky and Vathany Kulasingam: 1 shared paper
- Myron Cybulsky and Andrzej Chruscinski: 1 shared paper
- Myron Cybulsky and Vijay Ramaswamy: 1 shared paper
- Myron Cybulsky and Tony Mazzulli: 1 shared paper
- Myron Cybulsky and Jacques Genest: 1 shared paper
- Myron Cybulsky and Atul Humar: 1 shared paper
- Myron Cybulsky and Eric Bouffet: 1 shared paper
- Myron Cybulsky and Deepali Kumar: 1 shared paper
- Myron Cybulsky and Amit Oza: 1 shared paper
- Myron Cybulsky and Yiming Wang: 1 shared paper
- Myron Cybulsky and Livia Garzia: 1 shared paper
- Clinton Robbins and Slava Epelman: 1 shared paper
- Clinton Robbins and Jacques Genest: 1 shared paper
- Medicine
- Infectious Diseases
- Cardiology
- Toronto General Research Institute
- Department of Paediatrics
- Neurosurgery
- Laboratory Medicine & Pathobiology
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Clinton Robbins
Faculty
1 shared papers, latest 2022
Li Zhang
Laboratory Medicine & Pathobiology
1 shared papers, latest 2006
Slava Epelman
Cardiology
1 shared papers, latest 2017
Kenneth Aldape
Neurosurgery
1 shared papers, latest 2018
Vathany Kulasingam
Medicine
1 shared papers, latest 2021
Andrzej Chruscinski
Faculty
1 shared papers, latest 2021
Vijay Ramaswamy
Developmental Stem Cell Biology
1 shared papers, latest 2018
Tony Mazzulli
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2021
Jacques Genest
Cardiology
1 shared papers, latest 2022
Atul Humar
Infectious Diseases
1 shared papers, latest 2021
Eric Bouffet
Department of Paediatrics
1 shared papers, latest 2018
Deepali Kumar
Infectious Diseases
1 shared papers, latest 2021
Amit Oza
Faculty
1 shared papers, latest 2021
Yiming Wang
Pediatrics/Human Genetics
1 shared papers, latest 2017
Livia Garzia
Faculty
1 shared papers, latest 2018
Uri Tabori
Genetics and Genome Biology
1 shared papers, latest 2018
Michael Glogauer
Dentistry
1 shared papers, latest 2016
Robert Rottapel
Medical Biophysics
1 shared papers, latest 2016
Mansoor Husain
Medicine
1 shared papers, latest 2017
Minna Woo
Medicine
1 shared papers, latest 2022
Nada Jabado
Pediatrics
1 shared papers, latest 2018
Michael Brudno
Computer Science
1 shared papers, latest 2021
Paul Kubes
Physiology and Pharmacology
1 shared papers, latest 2016
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