Faculty profile

Pingzhao Hu

ResearcherBiochemistryWestern University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Western University directory, so their courses may be missing. Find their university profile.

Pingzhao Hu

Researcher

Biochemistry

Health Sciences

Western University

London, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
37 publications in the last five years, latest in 2027.
Senior (last) author on 24 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (7 CIHR, 2 NSERC), most recently in 2026.
Supervised 6 trainees who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

University Profile Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Read how they describe their research on their Western University profile.

Data Integration Machine Learning Deep Learning Drug Design Ai Agent Flare Joint Damage Joint Inflammation

Latest papers

Deep Learning Protocols for Predicting Drug Mechanism of Action and Drug-Target Interactions.
Methods in molecular biology (Clifton, N.J.) · 2027 · senior author
Human mesenchymal stromal cell extracellular vesicles maintain therapeutic miRNA cargo despite exposure to cystic fibrosis bronchoalveolar lavage fluid.
Cytotherapy · 2026
Toward Imbalanced Molecular Property Regression: A Benchmark Study and Interval-Aware Mixture of Experts.
Journal of chemical information and modeling · 2026 · senior author

All 37 publications

Latest funding

AI-Assisted Multimodal Imaging for Joint Damage Assessment, Flare Prediction, and Personalized Management of Rheumatoid Arthritis
CIHR · 2026 · Nominated PI
$1,154,386
Harnessing Cross-Biobank Genomic and Microbiome Data for AI-Accelerated Antibiotic Discovery in IBD
CIHR · 2025 · Supervisor
$120,000
AI-Driven De Novo Design of Pin1 Inhibitors for Precision Treatment of Triple-Negative Breast Cancer
CIHR · 2025 · Supervisor
$120,000

All 15 grants and awards

37 publications.

Deep Learning Protocols for Predicting Drug Mechanism of Action and Drug-Target Interactions.

Sun Y, Liu C, Jing Z, Li YY, Hu P

Methods in molecular biology (Clifton, N.J.)2027Senior author

DOI: 10.1007/978-1-0716-5539-9_3 PMID: 42734743

Human mesenchymal stromal cell extracellular vesicles maintain therapeutic miRNA cargo despite exposure to cystic fibrosis bronchoalveolar lavage fluid.

Rolandsson Enes S, Hampton TH, Barua J, Mui Z, Tertel T, Giebel B, McKenna DH, Hu P, Ashare A, Stanton BA, Dos Santos CC, Weiss DJ

Cytotherapy2026

DOI: 10.1016/j.jcyt.2026.102937 PMID: 42561645

Toward Imbalanced Molecular Property Regression: A Benchmark Study and Interval-Aware Mixture of Experts.

Sun Y, Shi Y, Deng A, Jing Z, Leung C, Hu P

Journal of chemical information and modeling2026Senior author

DOI: 10.1021/acs.jcim.6c01847 PMID: 42734549

Spatially guided translation from histology images to transcriptomic profiles using foundation model-driven contrastive learning.

Huang ZH, Xu Z, Hu P

PLoS computational biology2026Senior author

DOI: 10.1371/journal.pcbi.1014762 PMID: 42709893

Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis.

Matos A, Cawthorn WP, Marinho-Dias J, Ramalheira S, Roncon S, Pereira D, Ribeiro T, Rodrigues C, Mariz M, Miranda A, Brízido H, Bicho M, Medeiros P, Carneiro A, Trigo F, Hu P, Pereira F, Duarte H, Gray CD, Macgillivray T, Ramsay AG, Oliveira MJ, Ribeiro R

International journal of cancer2026

DOI: 10.1002/ijc.70480 PMID: 42003764

Deep Unsupervised Domain Adaptation for Translating Cancer Dependency Maps From Cell Lines to Breast Cancer Tumor Genomics.

Shi Y, Xu W, Hu P

Genetic epidemiology2026Senior author

DOI: 10.1002/gepi.70044 PMID: 42339999

Heterozygous Nonsense Mutation in the Nuclear Transport Factor KPNA7, a Maternal Factor Active in Embryonic Tissues, Causes Autosomal Dominant Otosclerosis.

Benteau T, Abdelfatah N, Griffin A, Penney C, Hu P, Stanton SG, Zhai G, Maheu M, French CR, Young TL

International journal of molecular sciences2026

DOI: 10.3390/ijms27114985 PMID: 42278511

A copula-infused graph neural network for cell type classification in single-cell RNA sequencing data.

Min S, Lac L, Hu P

Computational and structural biotechnology journal2026Senior author

DOI: 10.1016/j.csbj.2026.01.010 PMID: 41940310

GraphBAN: An inductive graph-based approach for enhanced prediction of compound-protein interactions.

Hadipour H, Li YY, Sun Y, Deng C, Lac L, Davis R, Cardona ST, Hu P

Nature communications2025Senior author

DOI: 10.1038/s41467-025-57536-9 PMID: 40102386

Enhanced Interpretable Neural Network Approach for Unified Batch Effect Mitigation and Disease Classification Using Cross-Cohort Microbiome Profiles.

Fung DLX, Khan MW, Leung CK, Hu P

Journal of computational biology : a journal of computational molecular cell biology2025Senior author

DOI: 10.1177/15578666251364292 PMID: 40780828

AI-Assisted Multimodal Imaging for Joint Damage Assessment, Flare Prediction, and Personalized Management of Rheumatoid Arthritis

Nominated PICIHR2026Project Grant

Principal investigators: Hu, Pingzhao; Hitchon, Carol A; O'Neil, Liam J; Pope, Janet E

Keywords: Ai Agent; Deep Learning; Flare; Joint Damage; Joint Inflammation; Large Language Model; Multimodal Imaging; Rheumatoid Arthritis; Thermal Imaging; X-Ray Imaging

$1,154,386

Harnessing Cross-Biobank Genomic and Microbiome Data for AI-Accelerated Antibiotic Discovery in IBD

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Janarthanan, Sugitha

Keywords: Artificial Intelligence; Bioinformatics; Disease Biomarkers; Drug Discovery; Inflammatory Bowel Disease

$120,000

AI-Driven De Novo Design of Pin1 Inhibitors for Precision Treatment of Triple-Negative Breast Cancer

SupervisorCIHR2025Doctoral Research Award - PA - Bioinformatics and Computational Biology

Principal investigators: Li, Yan Yi

Keywords: Admet Prediction; Ai-Driven Drug Discovery; Generative Modeling; Molecular Docking And Dynamics Simulations; Multi-Objective Optimization; Pin1 Inhibitor Design; Precision Oncology; Structure-Based De Novo Drug Design; Translational Breast Cancer Research; Triple-Negative Breast Cancer (Tnbc)

$120,000

AI-Driven Platform for Large-Scale Screening, Analysis, and Experimental Validation: Targeting Pin1 for Precision Drug Discovery in Triple-Negative Breast Cancer

Nominated PICIHR2025Project Grant

Principal investigators: Hu, Pingzhao; Kerr, Michael A; Lu, Kun Ping

Keywords: Data Integration; Drug Design; Drug Discovery Platform; In Vitro And In Vivo Experimental Validation; Machine Learning; Pin1 Inhibitors; Triple Negative Breast Cancer; Virtual Screening

$1,067,176

Discovery and Development of Pin1 inhibitors using generative AI

Nominated PICIHR2025Op. Gr.:CIHR-NSERC / Canada-France Call for Proposals on Artificial Intelligence

Principal investigators: Hu, Pingzhao

Keywords: Breast Cancer

$150,000

Physics-aware Reinforcement Learning-guided Quantum Flow Matching Model for 3D De Novo Inhibitor Design

Principal investigatorNSERC2025International - Catalyst - Quantum

Principal investigators: Hu, Pingzhao

Keywords: Information, computer and communication technologies; Medical and health sciences

$21,700

Optimizing Drug Combinations in Triple Negative Breast Cancer through A Graph Neural Network Approach for Enhanced Predictive Modeling

SupervisorCIHR2024CIHR Fellowship

Principal investigators: OLOULADE, BABATOUNDE MOCTARD

Keywords: Breast Cancer; Drug Combinations; Drug Discovery Applications; Graph Mamba Network; Molecular Graph Representation; Multimodal Data Integration; Neural Architecture Search; Reinforcement Learning

$210,000

Discovery and Development of Pin1 inhibitors using generative AI

Principal investigatorNSERC2024International - Collaboration - ANR - AI

Principal investigators: Hu, Pingzhao

Keywords: Life sciences (including biotechnology); Human health (including medically-related psychological research)

$150,000

Predicting Risks for Rheumatoid Arthritis Using Generative Artificial Intelligence

Nominated PICIHR2024Catalyst Grant: Analysis of CLSA Data

Principal investigators: Hu, Pingzhao

Keywords: Ai Interpretability; Denoising Diffusion Probabilistic Models; Disease Biomarkers; Disease Risk Prediction; Generative Ai; Genome-Wide Association Studies; Knockoff Inference; Polygenic Risk Score; Statistical Genetics

$70,000

An Interpretable and Inclusive AI Framework for COVID-19 Biomarker Discovery and Risk Prediction

SupervisorCIHR2024Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Wade, Kaitlyn E

Keywords: Artificial Intelligence; Bioinformatics; Biostatistics; Complex Diseases; Disease Biomarkers; Genome Wide Association Studies; Knockoff Inference; Polygenic Risk Score; Risk Prediction; Statistical Genetics

$120,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Something wrong or missing on this profile? Suggest a correction

Pingzhao Hu

Research

Latest papers

Latest funding

Deep Learning Protocols for Predicting Drug Mechanism of Action and Drug-Target Interactions.

Human mesenchymal stromal cell extracellular vesicles maintain therapeutic miRNA cargo despite exposure to cystic fibrosis bronchoalveolar lavage fluid.

Toward Imbalanced Molecular Property Regression: A Benchmark Study and Interval-Aware Mixture of Experts.

Spatially guided translation from histology images to transcriptomic profiles using foundation model-driven contrastive learning.

Systemic and Local Adiposity in the Bone Marrow Microenvironment Associated With Improved Prognosis in Hodgkin Lymphoma: Imaging and Molecular Analysis.

Deep Unsupervised Domain Adaptation for Translating Cancer Dependency Maps From Cell Lines to Breast Cancer Tumor Genomics.

Heterozygous Nonsense Mutation in the Nuclear Transport Factor KPNA7, a Maternal Factor Active in Embryonic Tissues, Causes Autosomal Dominant Otosclerosis.

A copula-infused graph neural network for cell type classification in single-cell RNA sequencing data.

GraphBAN: An inductive graph-based approach for enhanced prediction of compound-protein interactions.

Enhanced Interpretable Neural Network Approach for Unified Batch Effect Mitigation and Disease Classification Using Cross-Cohort Microbiome Profiles.

Physics-aware Reinforcement Learning-guided Quantum Flow Matching Model for 3D De Novo Inhibitor Design

Discovery and Development of Pin1 inhibitors using generative AI

Frequent collaborators

Pingzhao Hu

Prashen Chelikani

Wei Xu

Liam O'Neil

Anna Heath

Derek Jonker

Yongdong Ouyang

Terry-Lynn Young

Geoffrey Liu

Guangju Zhai

Brian Raught

Leigh Murphy

Laurent Brochard

Kyla Sask

Anna Heath

Karen Burns