This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Western University directory, so their courses may be missing. Find their university profile.
Research
Read how they describe their research on their Western University profile.
Latest papers
Role of organic anion transporting polypeptides in pancreatic statin disposition and islet cell function in mice.
Drug metabolism and disposition: the biological fate of chemicals · 2026
The antioxidant, N-acetyl-L-cysteine, affects beta cell oxidative stress, insulin secretion, and intracellular signaling pathways in MIN6 cells.
Cell and tissue research · 2025 · senior author
Long-Term Administration of Antioxidant N-Acetyl-L-Cysteine Impacts Beta Cell Oxidative Stress, Insulin Secretion, and Intracellular Signaling Pathways in Aging Mice.
Antioxidants (Basel, Switzerland) · 2025 · senior author
Latest funding
- $204,000
ß1-integrin is a crucial regulator of the exocytotic machinery in pancreatic beta-cells, affecting insulin secretion and integrin trafficking.
NSERC · 2017 · Principal investigator
- $711,450
Studies of the functional role of pancreatic stellate cells (PaSCs) during islet differentiation, regeneration and diabetes.
CIHR · 2016 · Nominated PI
- $703,126
Analysis of c-Kit and insulin receptor signaling interactions in regulating pancreatic beta-cell function and islet vasculature
CIHR · 2011 · Nominated PI
52 publications.
Role of organic anion transporting polypeptides in pancreatic statin disposition and islet cell function in mice.
Hu CB, Wang R, Tirona RG, Schwarz UI
The antioxidant, N-acetyl-L-cysteine, affects beta cell oxidative stress, insulin secretion, and intracellular signaling pathways in MIN6 cells.
Schuurman M, Wilson RB, Borradaile N, Wang R
Long-Term Administration of Antioxidant N-Acetyl-L-Cysteine Impacts Beta Cell Oxidative Stress, Insulin Secretion, and Intracellular Signaling Pathways in Aging Mice.
Schuurman M, Nguyen J, Wilson RB, Barillaro M, Wallace M, Borradaile N, Wang R
Elongation factor 1A1 inhibition elicits changes in lipid droplet size, the bulk transcriptome, and cell type-associated gene expression in MASLD mouse liver.
Wilson RB, Chen YJ, Zhang R, Maini S, Andrews TS, Wang R, Borradaile NM
Differential effects of OATP2B1 on statin accumulation and toxicity in a beta cell model.
Kwon J, Kim MS, Blagojevic C, Mailloux J, Medwid S, Tirona RG, Wang R, Schwarz UI
β1-Integrin-A Key Player in Controlling Pancreatic Beta-Cell Insulin Secretion via Interplay With SNARE Proteins.
Barillaro M, Schuurman M, Wang R
N-acetyl-L-cysteine treatment reduces beta-cell oxidative stress and pancreatic stellate cell activity in a high fat diet-induced diabetic mouse model.
Schuurman M, Wallace M, Sahi G, Barillaro M, Zhang S, Rahman M, Sawyez C, Borradaile N, Wang R
Collagen IV-β1-Integrin Influences INS-1 Cell Insulin Secretion via Enhanced SNARE Protein Expression.
Barillaro M, Schuurman M, Wang R
Activation of Pancreatic Stellate Cells Is Beneficial for Exocrine but Not Endocrine Cell Differentiation in the Developing Human Pancreas.
Li J, Chen B, Fellows GF, Goodyer CG, Wang R
The marine compound and elongation factor 1A1 inhibitor, didemnin B, provides benefit in western diet-induced non-alcoholic fatty liver disease.
Wilson RB, Chen YJ, Sutherland BG, Sawyez CG, Zhang R, Woolnough T, Hetherington AM, Peters KM, Patel K, Kennelly JP, Leonard KA, Schuurman M, Jacobs RL, Wang R, Borradaile NM
ß1-integrin is a crucial regulator of the exocytotic machinery in pancreatic beta-cells, affecting insulin secretion and integrin trafficking.
Principal investigators: Wang, Rennian
Studies of the functional role of pancreatic stellate cells (PaSCs) during islet differentiation, regeneration and diabetes.
Principal investigators: Wang, Rennian
Keywords: Diabetic Mouse Models; Human Fetal Pancreas; Islet Cell Differentiation; Islet Regeneration; Islet-Epithelial Cell Cluster Coculture; Pancreatic Duct Ligation; Pancreatic Stellate Cells; Pancreatic Stellate Cells Inhibitor
Analysis of c-Kit and insulin receptor signaling interactions in regulating pancreatic beta-cell function and islet vasculature
Principal investigators: Wang, Rennian
Keywords: Beta-Cell Specific C-Kit Transgenic Mice; C-Kit Wv Mutation Mice; Cross-Talk Between C-Kit And Insulin Receptors; High-Fat Diet Diabetes; Insulin Receptor/Insulin Receptor Substrates; Islet Biology; Islet Vasculature; Pi3k/Akt/Gsk3b Signaling Pathway; Stem Cell Factor/C-Kit Recptor; Vegf Expression
Role of fibrin-integrin interactions in supporting 2D and 3D pancreatic islet growth and function
Principal investigators: Wang, Rennian
Role of MENIN in the Developing Human Pancreas & Diabetes
Principal investigators: Wang, Rennian; Li, Xiao-Ying
Keywords: Diabetes; Human Fetal Pancreatic Development; Islet Proliferation And Differentiation; Men1/Menin; Signaling Pathway; Transcription Factors
Determination of the mechanisms by which Beta1-integrin regulates islet cell survival
Principal investigators: Wang, Rennian
Role of integrin-matrix interactions in Islet cell growth and differentiation
Principal investigators: Wang, Rennian
Cellular origins of pancreatic Beta cells: the role of growth factors and extracellular Matrix
Principal investigators: Wang, Rennian
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Physiology and Pharmacology
- Medical Biophysics
- Dentistry
- PATHOLOGY & LABORATORY MEDICINE, Western University
- Department of Medical Biophysics
- Medicine
- Department of Laboratory Medicine and Pathobiology
Co-authors at Western University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Nica Borradaile
Physiology and Pharmacology
3 shared papers, latest 2025
Steven Gallinger
Medical Biophysics
1 shared papers, latest 2015
Bertha Garcia
PATHOLOGY & LABORATORY MEDICINE, Western University
1 shared papers, latest 2010
Jaclyn Quirt
Medicine
1 shared papers, latest 2007
Gordon Keller
Medical Biophysics
1 shared papers, latest 2015
Cheryl Arrowsmith
Department of Medical Biophysics
1 shared papers, latest 2015
Andrew Leask
Dentistry
1 shared papers, latest 2013
Ming-Sound Tsao
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2015
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