Faculty profile

Simon Rousseau

ResearcherMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Simon Rousseau

Researcher

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
17 publications in the last five years, latest in 2026.
Senior (last) author on 3 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (3 NSERC, 2 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

238

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Endothelial Biology Long Covid Machine Learning Mass Spectrometry Mendelian Randomization Multiomic Observational Cohort Proteolysis

Latest papers

Unbiased characterization of COVID-19 endotypes leads to prognostication of high-risk individuals using routine blood tests.
Communications medicine · 2026
The Biobanque Québécoise de la COVID-19: Anticipate to Innovate.
Biopreservation and biobanking · 2026
Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.
The Journal of allergy and clinical immunology · 2026

All 72 publications

Latest funding

The evolving landscape of Long COVID: identifying dynamic molecular features to improve diagnosis, prognostication and identification of novel treatment targets
CIHR · 2025 · Nominated PI
$100,000
Mechanism and pharmacological modulation of intrinsic and acquired pro-inflammatory state of the airway epithelia in cystic fibrosis
CIHR · 2021 · Co-investigator
$841,500
COVID-19 and COPD: Important knowledge gaps in subclinical pulmonary disease in the Canadian population
CIHR · 2020 · Co-investigator
$275,554

All 11 grants and awards

72 publications.

Unbiased characterization of COVID-19 endotypes leads to prognostication of high-risk individuals using routine blood tests.

Ma W, Soulé A, Allard C, Durand M, Tremblay K, Rousseau S, Emad A

Communications medicine2026

DOI: 10.1038/s43856-026-01520-x PMID: 41832213

The Biobanque Québécoise de la COVID-19: Anticipate to Innovate.

Bhattacharjee M, Bérubé J, Durand M, Rousseau S, Zawati MH

Biopreservation and biobanking2026

DOI: 10.1177/19475535261429759 PMID: 41805007

Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.

Roussel L, Bernier S, Langelier M, Sun Y, Mak B, Li Y, Perez A, Wloski A, Angers I, Vinh LR, Beauchamp A, Boissel S, Watters AK, Rousseau S, Routy JP, Calderon V, Arias C, Vinh DC

The Journal of allergy and clinical immunology2026

DOI: 10.1016/j.jaci.2026.02.027 PMID: 41780571

Efficient and scalable construction of clinical variable networks for complex diseases with RAMEN.

Xiong Y, Wang J, Shang X, Chen T, Fraser DD, Fonseca GJ, Rousseau S, Ding J

Cell reports methods2025

DOI: 10.1016/j.crmeth.2025.101022 PMID: 40215965

Transcriptomic profiling of severe and critical COVID-19 patients reveals alterations in expression, splicing and polyadenylation.

Labrecque M, Brunet-Ratnasingham E, Hamilton LK, Auld D, Montpetit A, Richards B, Durand M, Rousseau S, Finzi A, Kaufmann DE, Tetreault M

Scientific reports2025

DOI: 10.1038/s41598-025-95905-y PMID: 40251257

COPD Exacerbations, Air Pollutant Fluctuations, and Individual-Level Factors in the Pandemic Era.

Mikaeeli S, Doiron D, Bourbeau J, Li PZ, Aaron SD, Chapman KR, Hernandez P, Maltais F, Marciniuk DD, O'Donnell DE, Sin DD, Walker BL, Tan WC, Rousseau S, Ross BA, CanCOLD Collaborative Research Group and the Canadian Respiratory Research Network

International journal of chronic obstructive pulmonary disease2025

DOI: 10.2147/copd.s498088 PMID: 40125072

Divergent responses to SARS-CoV-2 infection in bronchial epithelium with pre-existing respiratory diseases.

Oliva J, Ruffin M, Calmel C, Gibeaud A, Pizzorno A, Gaudin C, Chardonnet S, de Almeida Bastos V, Rosa-Calatrava M, Soulé A, Emad A, Rousseau S, Corvol H, Terrier O, Guillot L

iScience2025

DOI: 10.1016/j.isci.2025.111999 PMID: 40104058

Clustering and time series analyses of hybrid immunity to SARS-COV-2 using data from the BQC19 biobank.

Boulianne JF, Larocque D, Rousseau S, Bosson-Rieutort D

Scientific reports2025

DOI: 10.1038/s41598-025-18706-3 PMID: 41057392

IL-6 trans-signaling in cystic fibrosis bronchial cells potentiates TNF-α-driven ICAM-1 expression.

Lin J, Fourcade L, Roussel L, Marabella M, Bérubé J, Nguyen D, Rousseau S

Frontiers in cell and developmental biology2025Senior author

DOI: 10.3389/fcell.2025.1566482 PMID: 41063966

Circulating IL-17F, but not IL-17A, is elevated in severe COVID-19 and leads to an ERK1/2 and p38 MAPK-dependent increase in ICAM-1 cell surface expression and neutrophil adhesion on endothelial cells.

Bédard-Matteau J, Soulé A, Liu KY, Fourcade L, Fraser DD, Emad A, Rousseau S

Frontiers in immunology2024Senior author

DOI: 10.3389/fimmu.2024.1452788 PMID: 39493750

The evolving landscape of Long COVID: identifying dynamic molecular features to improve diagnosis, prognostication and identification of novel treatment targets

Nominated PICIHR2025Project Grant - PA: IMHA: Myalgic Encephalomyelitis

Principal investigators: Rousseau, Simon

Keywords: Endothelial Biology; Long Covid; Machine Learning; Mass Spectrometry; Mendelian Randomization; Multiomic; Observational Cohort; Proteolysis; Proteomic; Sars-Cov-2

$100,000

Mechanism and pharmacological modulation of intrinsic and acquired pro-inflammatory state of the airway epithelia in cystic fibrosis

Co-investigatorCIHR2021Project Grant

Principal investigators: Lukacs, Gergely L

Keywords: Bacterial Infection; Cf Therapy; Cftr; Cystic Fibrosis; Folding Corrector; Gating Potentiator; Innate Immunity; Proinflammatory Signalling; Pseudomonas Aeruginosa

$841,500

COVID-19 and COPD: Important knowledge gaps in subclinical pulmonary disease in the Canadian population

Co-investigatorCIHR2020Op Gr: COVID-19 Rapid Research FO - Clinical Mgmt/Health System Interventions

Principal investigators: Bourbeau, Jean; Tan, Wan

Keywords: Canadian Cohort Of Obstructive Lung Disease; Cancold; Chronic Obstructive Pulmonary Disease; Comorbidity; Copd; Coronavirus Sars-Cov-2; Corticosteroids; Covid-19; Cytokines; Inflammatory Mediators

$275,554

Genetic adaptation of Pseudomonas aeruginosa and lung inflammation

Co-investigatorCIHR2016Project Grant

Principal investigators: Nguyen, Dao

Keywords: Bacterial Pathogenesis; Cystic Fibrosis; Epithelial Cell; Host-Pathogen Interactions; Murine Infection Models; Pseudomonas Aeruginosa; Pulmonary Inflammation

$458,700

Chronic Obstructive Pulmonary Disease categorization using cardiovascular risk and levels of inflammatory mediators: a way toward more personalized care

Co-investigatorCIHR2016Project Grant

Principal investigators: Bourbeau, Jean

Keywords: Alarmins; Biomarkers; Cardiovascular Events; Cardiovascular Risk; Chronic Obstructive Pulmonary Disease; Disease Progression; Exacerbations; Inflammation; Signaling Pathways

$344,250

Functional consequences of dynamic MAPK signalling on the host defence response of vertebrates to bacterial infections

Principal investigatorNSERC2015Discovery Grants Program - Individual

Principal investigators: Rousseau, Simon

$170,000

Functional consequences of dynamic MAPK signalling on the host defence response of vertebrates to bacterial infections

Principal investigatorNSERC2014Discovery Grants Program - Individual

Principal investigators: Rousseau, Simon

$35,000

Investigating the Role of Neutrophil Extracellular Traps In Cancer Metastasis

Co-investigatorCIHR2013Operating Grant

Principal investigators: Ferri, Lorenzo

Keywords: Beta 1 Integrin; Cancer Metastasis; Ceacam; Intracellular Signalling; Intravital Microscopy; Liver; Neutrophil Extracellular Traps; Neutrophils

$707,578

Role of epithelium-derived IL-33 in driving lung inflammation in Cystic Fibrosis patients

Nominated PICIHR2012Operating Grant

Principal investigators: Rousseau, Simon

Keywords: Alarmins; Cell Death; Epithelium; Inflammation; Lung Diseases; Mouse Model Of Infection; Pseudomonas Aeruginosa; Pulmonary Exacerbation; Signal Transduction; Sputum

$571,721

Acute bacterial infection promotes cancer metastasis through toll like receptor signal transduction

Co-investigatorCIHR2011Operating Grant

Principal investigators: Ferri, Lorenzo

Keywords: Bacteria; Intravital Microscopy; Lung Cancer; Metastasis; Mice; Pneumonia; Signal Transduction; Toll Like Receptor

$497,573

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2025

Subject: Prospective PhD student: Endothelial Biology Dear Professor Rousseau, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Unbiased characterization of COVID-19 endotypes leads to prognostication of high-risk individuals using routine blood tests." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "The evolving landscape of Long COVID: identifying dynamic molecular features to improve diagnosis, prognostication and identification of novel treatment targets" (2025), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]

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Simon Rousseau

Research

Latest papers

Latest funding

Unbiased characterization of COVID-19 endotypes leads to prognostication of high-risk individuals using routine blood tests.

The Biobanque Qu&#xe9;b&#xe9;coise de la COVID-19: Anticipate to Innovate.

Human retinoic acid-inducible gene I (RIG-I) deficiency associated with susceptibility to classic Kaposi sarcoma.

Efficient and scalable construction of clinical variable networks for complex diseases with RAMEN.

Transcriptomic profiling of severe and critical COVID-19 patients reveals alterations in expression, splicing and polyadenylation.

COPD Exacerbations, Air Pollutant Fluctuations, and Individual-Level Factors in the Pandemic Era.

Divergent responses to SARS-CoV-2 infection in bronchial epithelium with pre-existing respiratory diseases.

Clustering and time series analyses of hybrid immunity to SARS-COV-2 using data from the BQC19 biobank.

IL-6 trans-signaling in cystic fibrosis bronchial cells potentiates TNF-&#x3b1;-driven ICAM-1 expression.

Circulating IL-17F, but not IL-17A, is elevated in severe COVID-19 and leads to an ERK1/2 and p38 MAPK-dependent increase in ICAM-1 cell surface expression and neutrophil adhesion on endothelial cells.

Functional consequences of dynamic MAPK signalling on the host defence response of vertebrates to bacterial infections

Functional consequences of dynamic MAPK signalling on the host defence response of vertebrates to bacterial infections

Frequent collaborators

Dao Nguyen

Danuta Radzioch

Emmanuelle Brochiero

Andrea Benedetti

Vincent Mooser

Andrea Benedetti

Madeleine Durand

Lorenzo Ferri

Jun Ding

Yann Joly

Madeleine Durand

Parameswaran Krishna Nair

Jason Matthews

Martin Sirois

Morag Park

Dusica Maysinger

Jean Bourbeau

Anne-Marie Mes-Masson

Nathalie Grandvaux

Jean-Pierre Routy

Nicole Beauchemin

Andrew McArthur

Gerard Wright

David Wishart

The Biobanque Québécoise de la COVID-19: Anticipate to Innovate.

IL-6 trans-signaling in cystic fibrosis bronchial cells potentiates TNF-α-driven ICAM-1 expression.