Faculty profile

Nicole Beauchemin

ResearcherOncologyMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Nicole Beauchemin

Researcher

Oncology

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
8 publications in the last five years, latest in 2024.
Principal investigator on 6 research grants (6 CIHR), most recently in 2015.
Supervised 1 trainee who won CIHR awards, most recently in 2010.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Metastasis Basic Mechanisms Cancer Drug Discovery Epigenetic Oncology Scientific Meeting Angiogenesis

Latest papers

Mechanism and function of CEACAM1 splice isoforms.
European journal of clinical investigation · 2024
Structural aspects of CEACAM1 interactions.
European journal of clinical investigation · 2024
High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance.
Communications medicine · 2024

All 39 publications

Latest funding

29th Annual International CEA Symposium
CIHR · 2019 · Co-investigator
$10,000
Montreal International Symposium on Angiogenesis and Metastasis (MISAM) 2016
CIHR · 2015 · Nominated PI
$8,825
Montreal International Symposium on Angiogenesis and Metastasis 2013
CIHR · 2012 · Nominated PI
$22,500

All 11 grants and awards

39 publications.

Mechanism and function of CEACAM1 splice isoforms.

Dery KJ, Najjar SM, Beauchemin N, Shively JE, Kupiec-Weglinski JW

European journal of clinical investigation2024

DOI: 10.1111/eci.14350 PMID: 39674874

Structural aspects of CEACAM1 interactions.

Gandhi AK, Huang YH, Sun ZJ, Kim WM, Kondo Y, Hanley T, Beauchemin N, Blumberg RS

European journal of clinical investigation2024

DOI: 10.1111/eci.14357 PMID: 39555955

High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance.

Huang YH, Yoon CH, Gandhi A, Hanley T, Castrillon C, Kondo Y, Lin X, Kim W, Yang C, Driouchi A, Carroll M, Gray-Owen SD, Wesemann DR, Drake CG, Bertagnolli MM, Beauchemin N, Blumberg RS

Communications medicine2024

DOI: 10.1038/s43856-024-00525-8 PMID: 38956268

Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Huang YH, Zhu C, Kondo Y, Anderson AC, Gandhi A, Russell A, Dougan SK, Petersen BS, Melum E, Pertel T, Clayton KL, Raab M, Chen Q, Beauchemin N, Yazaki PJ, Pyzik M, Ostrowski MA, Glickman JN, Rudd CE, Ploegh HL, Franke A, Petsko GA, Kuchroo VK, Blumberg RS

Nature2024

DOI: 10.1038/s41586-024-07164-y PMID: 38336833

Regulation of PPARγ2 Stability and Activity by SHP-1.

Kumar A, Laborit Labrada B, Lavallée-Bourget MH, Forest MP, Schwab M, Bellmann K, Houde V, Beauchemin N, Laplante M, Marette A

Molecular and cellular biology2024

DOI: 10.1080/10985549.2024.2354959 PMID: 38828991

SHP-1 phosphatase acts as a coactivator of PCK1 transcription to control gluconeogenesis.

Kumar A, Schwab M, Laborit Labrada B, Silveira MAD, Goudreault M, Fournier É, Bellmann K, Beauchemin N, Gingras AC, Bilodeau S, Laplante M, Marette A

The Journal of biological chemistry2023

DOI: 10.1016/j.jbc.2023.105164 PMID: 37595871

Structural analysis of human CEACAM1 oligomerization.

Gandhi AK, Sun ZJ, Huang YH, Kim WM, Yang C, Petsko GA, Beauchemin N, Blumberg RS

Communications biology2022

DOI: 10.1038/s42003-022-03996-4 PMID: 36180783

Loss of NFE2L3 protects against inflammation-induced colorectal cancer through modulation of the tumor microenvironment.

Saliba J, Coutaud B, Makhani K, Epstein Roth N, Jackson J, Park JY, Gagnon N, Costa P, Jeyakumar T, Bury M, Beauchemin N, Mann KK, Blank V

Oncogene2022

DOI: 10.1038/s41388-022-02192-2 PMID: 35091681

Neutrophil Extracellular Trap-Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma.

Rayes RF, Vourtzoumis P, Bou Rjeily M, Seth R, Bourdeau F, Giannias B, Berube J, Huang YH, Rousseau S, Camilleri-Broet S, Blumberg RS, Beauchemin N, Najmeh S, Cools-Lartigue J, Spicer JD, Ferri LE

Journal of immunology (Baltimore, Md. : 1950)2020

DOI: 10.4049/jimmunol.1900240 PMID: 32169849

Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer.

Jeyakumar T, Fodil N, Van Der Kraak L, Meunier C, Cayrol R, McGregor K, Langlais D, Greenwood CMT, Beauchemin N, Gros P

Scientific reports2019

DOI: 10.1038/s41598-019-55378-2 PMID: 31827213

29th Annual International CEA Symposium

Co-investigatorCIHR2019Planning and Dissemination Grant - Institute Community Support

Principal investigators: Gray-Owen, Scott D

Keywords: Angiogenesis; Cancer; Carcinoembryonic Antigen (Cea); Cea-Related Cell Adhesion Molecules (Ceacams); Cell Signaling; Diabetes; Infectious Disease; Pregnancy-Specific Glycoproteins

$10,000

Montreal International Symposium on Angiogenesis and Metastasis (MISAM) 2016

Nominated PICIHR2015Planning and Dissemination Grant - Institute Community Support

Principal investigators: Beauchemin, Nicole

Keywords: Basic Mechanisms; Cancer; Drug Discovery; Epigenetic; Metastasis; Oncology; Scientific Meeting

$8,825

Montreal International Symposium on Angiogenesis and Metastasis 2013

Nominated PICIHR2012Dissemination Events - Priority Announcement: Cancer Research

Principal investigators: Beauchemin, Nicole

Keywords: Angiogenesis; Brain Cancer; Metastasis; Public Lecture; Stem Cells; Therapies

$22,500

CEACAM1 in colon cancer progression and metastasis

Nominated PICIHR2011Operating Grant

Principal investigators: Beauchemin, Nicole

Keywords: Ceacam1; Colorectal Cancer; Cytokines; Inflammation; Knockout Mouse Model; Metastasis; Myeloid Derived Suppressor Cells; Shp-1; Stat3

$834,100

Colloque "Signalisation Québec 2012"

Co-investigatorCIHR2011Dissemination Events - Priority Announcement: Cancer Research

Principal investigators: Côté, Jean-François

Keywords: Cancer; Transduction Du Signal

$24,740

Defining and Applying "Oncometabolism": A team approach in understanding and translating the Warburg effect from oncogenic and tumour suppressing activities.

Co-investigatorCIHR2010Team Grant: Terry Fox New Frontiers Program in Cancer

Principal investigators: Tremblay, Michel L; Jones, Russell G; Pause, Arnim P; Sonenberg, Nahum; St-Pierre, Julie

Keywords: Amp Kinase; Anima Models Phenotyping; Bioenergetics; Cancer Prevention And Therapies; Cell Signaling; Oncometabolism; Protein Synthesis; Transcription Regulation Of Metabolic Genes; Tyrosine Phosphorylation; Warburg Effect

Montreal International Symposium on Angiogenesis and Metastasis 2011

Nominated PICIHR2010Dissemination Events

Principal investigators: Beauchemin, Nicole

Keywords: Angiogenesis; Colorectal Cancer; Liver Metastatis; Metastasis; Therapies

$18,180

Identification of Genetic Loci Controlling Susceptibility to Colitis-Associated Colorectal Cancer in Mice

SupervisorCIHR2010Doctoral Research Award - PA: Digestive Health (SHOPP)

Principal investigators: Van Der Kraak, Lauren A

Keywords: Azoxymethane; Colitis-Associated Colon Cancer; Dextran Sulfate Sodium; Familial Colon Cancer; Gene Mapping; Inflammatory Bowel Disease; Mouse Models

$72,000

20th Annual International CEA Symposium

Nominated PICIHR2009Meetings, Planning & Dissemination Grant: Cancer Research

Principal investigators: Beauchemin, Nicole

Keywords: Cancer Progression; Carcinoembryonic Antigen; Cell Adhesion Molecule; Immunology; Metabolism And Cancer

$10,000

Harnessing CEACAM Biology: From Cells to Tissues

Principal investigatorCIHR2009Emerging Team Grant: Regenerative Medicine and Nanomedicine - LOI

Principal investigators: Yip, Christopher M; Beauchemin, Nicole; Chan, Warren C; Gray-Owen, Scott D; Rocheleau, Jonathan V

Keywords: Cancer; Ceacam; Protein-Protein Interactions

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Nicole Beauchemin

Research

Latest papers

Latest funding

Mechanism and function of CEACAM1 splice isoforms.

Structural aspects of CEACAM1 interactions.

High-dimensional mapping of human CEACAM1 expression on immune cells and association with melanoma drug resistance.

Author Correction: CEACAM1 regulates TIM-3-mediated tolerance and exhaustion.

Regulation of PPAR&#x3b3;2 Stability and Activity by SHP-1.

SHP-1 phosphatase acts as a coactivator of PCK1 transcription to control gluconeogenesis.

Structural analysis of human CEACAM1 oligomerization.

Loss of NFE2L3 protects against inflammation-induced colorectal cancer through modulation of the tumor microenvironment.

Neutrophil Extracellular Trap-Associated CEACAM1 as a Putative Therapeutic Target to Prevent Metastatic Progression of Colon Carcinoma.

Inactivation of Interferon Regulatory Factor 1 Causes Susceptibility to Colitis-Associated Colorectal Cancer.

Frequent collaborators

Philippe Gros

Maya Saleh

David Langlais

Danuta Radzioch

Maryam Tabrizian

Mathieu Laplante

Gerald Batist

Jean-Philippe Gratton

Mathieu Blanchette

Anne-Marie Mes-Masson

Malika Oubaha

Morag Park

Peter Metrakos

Rima Rozen

Morag Park

Simon Rousseau

Anne-Claude Gingras

Volker Blank

Steve Bilodeau

Regulation of PPARγ2 Stability and Activity by SHP-1.