Mathieu Morissette

Research

Clinical Samples Emphysema Immunology Mouse Model Ptpn6 Smoking

Latest papers

Polygenic inheritance and its interplay with smoking history in predicting lung cancer diagnosis: a French-Canadian case-control cohort.
EBioMedicine · 2024
HSDL2 links nutritional cues to bile acid and cholesterol homeostasis.
Science advances · 2024
Asthma COPD overlap: Insights into cellular and molecular mechanisms.
Molecular aspects of medicine · 2022 · first author

All 6 publications

Latest funding

Are e-cigarettes really a healthy alternative to combustible cigarettes? Cardiorespiratory, immune and thrombotic responses to smoking e-cigarettes vs combustible cigarettes under conditions of physical and mental stress
CIHR · 2020 · Co-investigator
$25,000
Deciphering the role of PTPN6/SHP-1 and its mutant PTPN6/SHP-1Ala455Thr in the development of pulmonary emphysema
CIHR · 2019 · Nominated PI
$707,626
Role of specific inflammatory cells and mediators in the pulmonary response to cigarette smoke exposure
CIHR · 2018 · Supervisor
$105,000

All 3 grants and awards

6 publications.

01

Polygenic inheritance and its interplay with smoking history in predicting lung cancer diagnosis: a French-Canadian case-control cohort.

Boumtje V, Manikpurage HD, Li Z, Gaudreault N, Armero VS, Boudreau DK, Renaut S, Henry C, Racine C, Eslami A, Bougeard S, Vigneau E, Morissette M, Arsenault BJ, Labbé C, Laliberté AS, Martel S, Maltais F, Couture C, Desmeules P, Mathieu P, Thériault S, Joubert P, Bossé Y

EBioMedicine2024

DOI: 10.1016/j.ebiom.2024.105234 PMID: 38970920

02

HSDL2 links nutritional cues to bile acid and cholesterol homeostasis.

Samson N, Bosoi CR, Roy C, Turcotte L, Tribouillard L, Mouchiroud M, Berthiaume L, Trottier J, Silva HCG, Guerbette T, Plata-Gómez AB, Besse-Patin A, Montoni A, Ilacqua N, Lamothe J, Citron YR, Gélinas Y, Gobeil S, Zoncu R, Caron A, Morissette M, Pellegrini L, Rochette PJ, Estall JL, Efeyan A, Shum M, Audet-Walsh É, Barbier O, Marette A, Laplante M

Science advances2024

DOI: 10.1126/sciadv.adk9681 PMID: 38820148

03

Asthma COPD overlap: Insights into cellular and molecular mechanisms.

Morissette M, Godbout K, Côté A, Boulet LP

Molecular aspects of medicine2022First author

DOI: 10.1016/j.mam.2021.101021 PMID: 34521557

04

Cigarette smoke augments CSF3 expression in neutrophils to compromise alveolar–capillary barrier function during influenza infection

McGrath JJC, Vanderstocken G, Dvorkin-Gheva A, Cass SP, Afkhami S, Fantauzzi MF, Thayaparan D, Reihani A, Wang P, Beaulieu A

European Respiratory Journal202214 citations

DOI: 10.1183/13993003.02049-2021

05

Intranasal versus intratracheal exposure to lipopolysaccharides in a murine model of acute respiratory distress syndrome.

Khadangi F, Forgues AS, Tremblay-Pitre S, Dufour-Mailhot A, Henry C, Boucher M, Beaulieu MJ, Morissette M, Fereydoonzad L, Brunet D, Robichaud A, Bossé Y

Scientific reports2021

DOI: 10.1038/s41598-021-87462-x PMID: 33833346

06

Lung cancer susceptibility genetic variants modulate HOXB2 expression in the lung.

Clemenceau A, Boucherat O, Landry-Truchon K, Lamontagne M, Biardel S, Joubert P, Gobeil S, Secco B, Laplante M, Morissette M, Obeidat M, Timens W, Jeannotte L, Bossé Y

The International journal of developmental biology2018

DOI: 10.1387/ijdb.180210yb PMID: 30604855

Are e-cigarettes really a healthy alternative to combustible cigarettes? Cardiorespiratory, immune and thrombotic responses to smoking e-cigarettes vs combustible cigarettes under conditions of physical and mental stress

Co-investigatorCIHR2020Catalyst Grant: Health Effects of Vaping

Principal investigators: Bacon, Simon L; Lavoie, Kim

Keywords: Cardiovascular Reactivity; Chronic Disease Prevention; Electronic Cigarettes; Exercise; Lung Function; Mental Stress; Safety; Smoking; Stress Reactivity; Vascular Function

$25,000

Deciphering the role of PTPN6/SHP-1 and its mutant PTPN6/SHP-1Ala455Thr in the development of pulmonary emphysema

Nominated PICIHR2019Project Grant

Principal investigators: Morissette, Mathieu

Keywords: Clinical Samples; Emphysema; Immunology; Mouse Model; Ptpn6; Smoking

$707,626

Role of specific inflammatory cells and mediators in the pulmonary response to cigarette smoke exposure

SupervisorCIHR2018Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: Milad, Nadia

Keywords: Alveolar Macrophages; Chemokines; Chronic Obstructive Pulmonary Disease; Cigarette Smoke; Cytokines; Emphysema; Host Defense; Immunology; Neutrophils; Pulmonary Inflammation

$105,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Medicine
Médecine
Pathology & Molecular Medicine
Biochemistry & Biomedical Sciences
Surgery
Other

1 shared papers, latest 2018

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Applying for

Paper to mentionMention their CIHR grant from 2019

Subject: Prospective PhD student: Clinical Samples Dear Professor Morissette, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Polygenic inheritance and its interplay with smoking history in predicting lung cancer diagnosis: a French-Canadian case-control cohort." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Deciphering the role of PTPN6/SHP-1 and its mutant PTPN6/SHP-1Ala455Thr in the development of pulmonary emphysema" (2019), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]