Faculty profile

Daniel Sinnett

ResearcherPharmacologie - PhysiologieUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Daniel Sinnett

Researcher

Pharmacologie - Physiologie

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
54 publications in the last five years, latest in 2026.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (10 CIHR), most recently in 2024.
Supervised 3 trainees who won CIHR awards, most recently in 2019.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

161

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Mass Spectrometry Rna Methylation Acute Lymphoblastic Leukemia Circular Rna Crispr/Cas Exosomes Lncrna Rna

Latest papers

Genetic Determinants of Treatment-Related Bone Toxicity in Pediatric Acute Lymphoblastic Leukemia.
Clinical pharmacology and therapeutics · 2026
Extrachromosomal microDNA Signature as a Candidate Biomarker in Pediatric Acute Lymphoblastic Leukemia.
Cancer research communications · 2026
Implementing health promotion interventions in a pediatric oncology setting: A qualitative study among families impacted by cancer and healthcare professionals.
Journal of child health care : for professionals working with children in the hospital and community · 2026

All 161 publications

Latest funding

Exploring non-coding RNAs in childhood acute lymphoblastic leukemia
CIHR · 2024 · Nominated PI
$979,200
CircRNAome in childhood TCF3-PBX1 ALL: Biomaker potential and mechanisms of circRNA dysregulation and function
CIHR · 2022 · Nominated PI
$100,000
The Canadian Behavioural Trials and Interventions Training Platform
CIHR · 2022 · Co-investigator
$444,018

All 22 grants and awards

From the 150 most recent of 161 publications.

Genetic Determinants of Treatment-Related Bone Toxicity in Pediatric Acute Lymphoblastic Leukemia.

Abaji R, Gagné V, Espagne É, Alos N, Del Vecchio V, Ait Said L, Shalmiev A, Fuchs C, Laverdière C, Leclerc JM, Sallan SE, Silverman LB, Sinnett D, Tran TH, Krajinovic M

Clinical pharmacology and therapeutics2026

DOI: 10.1002/cpt.70371 PMID: 42325004

Extrachromosomal microDNA Signature as a Candidate Biomarker in Pediatric Acute Lymphoblastic Leukemia.

Brukner I, Gagné V, Richard-St-Hilaire A, Tremblay-Dauphinais P, Fuchs C, Bittencourt H, Veres T, Sinnett D, Krajinovic M

Cancer research communications2026

DOI: 10.1158/2767-9764.crc-25-0419 PMID: 41379638

Implementing health promotion interventions in a pediatric oncology setting: A qualitative study among families impacted by cancer and healthcare professionals.

Demers C, Gélinas I, Kerba J, Lee K, Bourque CJ, Lamore K, Bouchard I, Meloche C, Laverdière C, Curnier D, Marcil V, Sultan S, Sinnett D, Higgins J

Journal of child health care : for professionals working with children in the hospital and community2026

DOI: 10.1177/13674935251341008 PMID: 40340638

EV-Blade: an automated centrifugal-pneumatic cartridge for size- and affinity-based exosome isolation from whole blood.

Poncelet L, Morton KJ, Shiu M, Veilleux G, Richer C, Clime L, Sinnett D, Veres T

Lab on a chip2026

DOI: 10.1039/d5lc00977d PMID: 41590026

HLA-B15:01 and HLA-DRB107:01 as novel markers of acute GVHD in pediatric HSCT.

Mootoosamy C, Ansari M, Gagné V, St-Onge P, Tremblay-Dauphinais P, Beaulieu P, Théorêt Y, Nava T, Mlakar V, Gloor YS, Villard J, Boelens JJ, Bredius RGM, Dalle JH, Lewis V, Kałwak K, Sinnett D, Bittencourt H, Krajinovic M, Pediatric Disease Working Parties of the European Blood and Bone Marrow Transplant Group

Bone marrow transplantation2026

DOI: 10.1038/s41409-026-02972-4 PMID: 42457985

Cell-Free DNA Uncovered Tumor Heterogeneity and Informed Targeted Therapy in a Pediatric Rhabdomyosarcoma.

Faucher J, Richer C, Langlois S, Rouette A, Bianco S, Sontag T, Lepage MÈ, Da Silva E, Cellot S, Tran TH, Parbhoo K, Cottrell CE, Sinnett D, Michon B, Lavallée VP, Santiago R

JCO precision oncology2026

DOI: 10.1200/po-25-00948 PMID: 42114036

IL1B rs1143627 and IL17A rs8193036 in the risk of Acute Graft Versus Host Disease in pediatric HSCT.

Mootoosamy C, Ansari M, Gagné V, Chatelain-Laflamme A, Flament C, Zekraoui O, Nyambi M, Théorêt Y, Nava T, Mlakar V, Gloor YS, Villard J, Boelens JJ, Bredius RGM, Dalle JH, Lewis V, Kałwak K, Sinnett D, Bittencourt H, Krajinovic M

Leukemia research2026

DOI: 10.1016/j.leukres.2026.108189 PMID: 41775174

Acceptability and functional benefits of a health promotion program in pediatric oncology: a mixed-methods study

Demers C, Higgins J, Kerba J, Bouchard I, Meloche C, Curnier D, Marcil V, Sultan S, Laverdière C, Sinnett D

Frontiers in Pediatrics20261 citations

DOI: 10.3389/fped.2026.1753530

Long Circulating RNAs Packaged in Extracellular Vesicles: Prospects for Improved Risk Assessment in Childhood B-Cell Acute Lymphoblastic Leukemia.

Poncelet L, Richer C, Gutierrez-Camino A, Veres T, Sinnett D

International journal of molecular sciences2025Senior author

DOI: 10.3390/ijms26093956 PMID: 40362196

Rescuing DNMT1 fails to fully reverse the molecular and functional repercussions of its loss in mouse embryonic stem cells.

Elder E, Lemieux A, Legault LM, Caron M, Bertrand-Lehouillier V, Dupas T, Raynal NJ, Bourque G, Sinnett D, Gévry N, McGraw S

Nucleic acids research2025

DOI: 10.1093/nar/gkaf130 PMID: 39997223

Exploring non-coding RNAs in childhood acute lymphoblastic leukemia

Nominated PICIHR2024Project Grant

Principal investigators: Sinnett, Daniel; Lecuyer, Eric

Keywords: Acute Lymphoblastic Leukemia; Circular Rna; Crispr/Cas; Exosomes; Lncrna; Mass Spectrometry; Rna; Rna Methylation; Rnaseq

$979,200

CircRNAome in childhood TCF3-PBX1 ALL: Biomaker potential and mechanisms of circRNA dysregulation and function

Nominated PICIHR2022Project Grant - Priority Announcement: Pediatric Cancer Research

Principal investigators: Sinnett, Daniel

Keywords: Cas13d; Circrna; Leukemia; Mass Spectrometry; Rna Binding Proteins; Rna Methylation; Rna-Seq

$100,000

The Canadian Behavioural Trials and Interventions Training Platform

Co-investigatorCIHR2022Training Grant: Clinical Trials Training Platforms - Indirect Costs

Principal investigators: Bacon, Simon L; Alberga, Angela S; Campbell, Tavis S; Carlson, Linda E; Gordon, Jennifer L; Jung, Mary E; Lavoie, Kim; Locke, Sean R; Presseau, Justin; Rash, Josh A; Vallis, Micheal T

Keywords: Behaviour Change; Behavioural Medicine; Behavioural Trials; Healthcare Implementation; Innovative Trial Designs; Medication And Vaccination Adherence

$444,018

The Canadian Behavioural Trials and Interventions Training Platform

Co-investigatorCIHR2022Training Grant: Clinical Trials Training Platforms

Keywords: Behaviour Change; Behavioural Medicine; Behavioural Trials; Healthcare Implementation; Innovative Trial Designs; Medication And Vaccination Adherence

$1,776,068

4D spheroids identify type I protein arginine methyltransferases as a target in NSCLC

Principal investigatorCIHR2020Project Grant - PA: Epigenetics/epigenomics in human health or disease

Principal investigators: Raynal, Noël J; Richard, Stéphane; Sinnett, Daniel

Keywords: Chromatin; Dna Methylation; Drug Screening; Epigenetics; Lung Cancer Models; Protein Arginine Methyltransferase; Single-Cell Rna Sequencing; Spheroids

$100,000

Implication of early embryonic epigenetic dysregulation in fetal alcohol spectrum disorders-associated outcomes

Co-investigatorCIHR2020Project Grant

Principal investigators: McGraw, Serge

Keywords: Adverse Maternal Exposure; Brain Development; Developmental Origin Of Health And Diseases (Dohad); Dna Methylation; Epigenetics; Fetal Alcohol Spectrum Disorders; Fetal Development; Gabaergic Interneurons; Transcriptomics

$826,200

Assessment of the role of circRNAs in childhood acute lymphoblastic leukemia

SupervisorCIHR2019CIHR Fellowship

Principal investigators: Gutierrez Camino, Angela

Keywords: Circrnas; Leukemia; Non-Coding Rnas; Pediatric

$90,000

ACI IG 2014 Programme de bourses d’été pour étudiants de premier cycle: Biologie computationnelle - Analyse de données de séquençage génomique de patients subissant une greffe de melle osseuse.

SupervisorCIHR2014Undergraduate: Summer Studentship Award - Institute Community Support

Principal investigators: Mehanna, Paméla

Keywords: Séquençage Génomique

$5,000

Clinical evaluation of surface-plasmon resonance and nanoparticle-based fluorescent detection of serum biomarkers

Co-investigatorCIHR2012Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Pelletier, Joelle N; Masson, Jean-Francois

Keywords: Cancer Biomarker; Cancer Treatment; Fluorescence; Nanoparticle; Pharmacokinetics; Portable Device; Surface Plasmon Resonance; Ultra-Low Fouling Surfaces

$328,059

Genomic determinants of common long-term treatment effects in childhood acute lymphoblastic leukemia survivors

Nominated PICIHR2011Team Grant: Childhood Cancer - Late Effects of Treatment

Principal investigators: Sinnett, Daniel; Alos, Nathalie B; Andelfinger, Gregor U; Krajinovic, Maja; Laverdière, Caroline; Levy, Emile; Robaey, Philippe

Keywords: Biostatistics; Bone Morbidity; Cancer Survivorship; Cardiotoxicity; Childhood Leukemia; Long-Term Disease Outcomes/Biomarkers; Medical Genomics; Metabolic Syndrome; Neurocognition; Next-Generation Sequencing/Dna Variants

$2,445,054

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Daniel Sinnett

Research

Latest papers

Latest funding

Genetic Determinants of Treatment-Related Bone Toxicity in Pediatric Acute Lymphoblastic Leukemia.

Extrachromosomal microDNA Signature as a Candidate Biomarker in Pediatric Acute Lymphoblastic Leukemia.

Implementing health promotion interventions in a pediatric oncology setting: A qualitative study among families impacted by cancer and healthcare professionals.

EV-Blade: an automated centrifugal-pneumatic cartridge for size- and affinity-based exosome isolation from whole blood.

HLA-B*15:01 and HLA-DRB1*07:01 as novel markers of acute GVHD in pediatric HSCT.

Cell-Free DNA Uncovered Tumor Heterogeneity and Informed Targeted Therapy in a Pediatric Rhabdomyosarcoma.

IL1B rs1143627 and IL17A rs8193036 in the risk of Acute Graft Versus Host Disease in pediatric HSCT.

Acceptability and functional benefits of a health promotion program in pediatric oncology: a mixed-methods study

Long Circulating RNAs Packaged in Extracellular Vesicles: Prospects for Improved Risk Assessment in Childhood B-Cell Acute Lymphoblastic Leukemia.

Rescuing DNMT1 fails to fully reverse the molecular and functional repercussions of its loss in mouse embryonic stem cells.

Frequent collaborators

Emile Levy

Gregor Andelfinger

Nada Jabado

Philippe Robaey

Michel Duval

Guillaume Bourque

Victor Lewis

Sonia Cellot

Devendra Amre

Tomi Pastinen

Ivan Brukner

Louis-Nicolas Veilleux

David Ogez

Elie Haddad

Ioannis Ragoussis

Frank Rauch

Ali Ahmad

Denise Avard

Arnaud Droit

Sylvie Girard

Serge McGraw

Valérie Larouche

Leandra Desjardins

Julie Hussin

Gino Somers

Marie-Claude Pelland-Marcotte

Claude Bhérer

Jason Karamchandani

Jason Karamchandani

Chantal Autexier

Louis Flamand

Xavier Banquy

HLA-B15:01 and HLA-DRB107:01 as novel markers of acute GVHD in pediatric HSCT.