This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.
Research
Latest papers
IKAROS: from chromatin organization to transcriptional elongation control.
Cell death and differentiation · 2025 · senior author
MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes.
Frontiers in immunology · 2024 · senior author
An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes.
iScience · 2023
Latest funding
- $110,438
A histology suite for visualizing cell distribution in tissues
NSERC · 2024 · Co-investigator
- $868,275
Influence of Ikaros on treatment response in Acute Lymphoblastic Leukemia
CIHR · 2021 · Nominated PI
- $192,000
Determination of the importance of MNDA and the potential implication of other PYHIN factors in (pre-)mRNA processing
NSERC · 2019 · Principal investigator
19 publications.
IKAROS: from chromatin organization to transcriptional elongation control.
Affar M, Bottardi S, Quansah N, Lemarié M, Ramón AC, Affar EB, Milot E
MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes.
Bottardi S, Layne T, Ramòn AC, Quansah N, Wurtele H, Affar EB, Milot E
An inventory of crosstalk between ubiquitination and other post-translational modifications in orchestrating cellular processes.
Barbour H, Nkwe NS, Estavoyer B, Messmer C, Gushul-Leclaire M, Villot R, Uriarte M, Boulay K, Hlayhel S, Farhat B, Milot E, Mallette FA, Daou S, Affar EB
USP42 deubiquitinase in the arena of liquid-liquid phase separation and nuclear speckles.
Uriarte M, Milot E, Affar EB
MNDA controls the expression of MCL-1 and BCL-2 in chronic lymphocytic leukemia cells.
Bottardi S, Guieze R, Bourgoin V, Fotouhi-Ardakani N, Dougé A, Darracq A, Lakehal YA, Berger MG, Mollica L, Bay JO, Omichinski JG, Milot E
NPM and NPM-MLF1 interact with chromatin remodeling complexes and influence their recruitment to specific genes.
Darracq A, Pak H, Bourgoin V, Zmiri F, Dellaire G, Affar EB, Milot E
IKAROS: a multifunctional regulator of the polymerase II transcription cycle.
Bottardi S, Mavoungou L, Milot E
The IKAROS interaction with a complex including chromatin remodeling and transcription elongation activities is required for hematopoiesis.
Bottardi S, Mavoungou L, Pak H, Daou S, Bourgoin V, Lakehal YA, Affar el B, Milot E
Direct protein interactions are responsible for Ikaros-GATA and Ikaros-Cdk9 cooperativeness in hematopoietic cells.
Bottardi S, Mavoungou L, Bourgoin V, Mashtalir N, Affar el B, Milot E
Neuronal ER stress impedes myeloid-cell-induced vascular regeneration through IRE1α degradation of netrin-1.
Binet F, Mawambo G, Sitaras N, Tetreault N, Lapalme E, Favret S, Cerani A, Leboeuf D, Tremblay S, Rezende F, Juan AM, Stahl A, Joyal JS, Milot E, Kaufman RJ, Guimond M, Kennedy TE, Sapieha P
A histology suite for visualizing cell distribution in tissues
Principal investigators: Lesage, Sylvie
Keywords: Cellular positioning; Fluorecent microscopy; Histology; Microscopy; Tissue sections
Influence of Ikaros on treatment response in Acute Lymphoblastic Leukemia
Principal investigators: Milot, Eric
Keywords: Acute Lymphoblastic Leukemia; Dna-Rna Hybrids; Genomic Instability; Ikaros; Protein Interactome; R-Chip-Seq
Determination of the importance of MNDA and the potential implication of other PYHIN factors in (pre-)mRNA processing
Principal investigators: Milot, Eric
A Benchtop Cell Sorter for Accelerating the Discovery of Physiopathological Processes
Principal investigators: Milot, ERIC
A microcalorimetry system to define the biochemical parameters of molecular interactions
Principal investigators: Affar, ElBachir
Indentification of MNDA modifications and domains involved in regulation of apoptosis
Principal investigators: Milot, Eric
Ikaros regulation of transcription elongation and its importance during hematopoiesis
Principal investigators: Milot, Eric
Keywords: Bcl-Xl; Chip-Seq; Hematopoiesis; Ikaros; Leukemia; Mouse Models; Rna-Seq; Signalling Pathway; Transcription Elongation; Transcription Factors
Effect of NPM mutation and NPM-MLF1 translocation on gene regulation
Principal investigators: Milot, Eric
Keywords: Epigenetic Regulation; Gene Expression; Genomic Mutation; Hematopoiesis; Human Bone Marrow; Leukemia; Mouse Models; Nucleophosmin; Protein Complex
Mechanisms of epigenetic regulation and hematopoietic lineage specification
Principal investigators: Milot, Eric
Keywords: Epigenetic Regulation; Gene Expression; Hematopoiesis; Human Bone Marrow; Leukemia; Mouse Models
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Medicine
- Pediatrics
- Pathology
- Centre de recherche
- Ophthalmology
- Engineering Physics
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Marie Trudel
Medicine
2 shared papers, latest 2009
Elliot Drobetsky
Medicine
1 shared papers, latest 2009
Przemyslaw Sapieha
Ophthalmology
1 shared papers, latest 2013
Przemyslaw Sapieha
Engineering Physics
1 shared papers, latest 2013
Jean-Sébastien Joyal
Pediatrics
1 shared papers, latest 2013
Graham Dellaire
Pathology
1 shared papers, latest 2019
Sophie Tremblay
Pediatrics
1 shared papers, latest 2013
Hugo Wurtele
Centre de recherche
1 shared papers, latest 2024
Volker Blank
Medicine
1 shared papers, latest 2006
A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.