This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.
Research
Latest papers
Focus on numbers - characterizing protein accumulation at DNA double-strand breaks.
Journal of cell science · 2025
Functional studies in yeast confirm the pathogenicity of a new GINS3 Meier-Gorlin syndrome variant.
Clinical genetics · 2024 · senior author
MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes.
Frontiers in immunology · 2024
Latest funding
- $1,500
Replication protein A availability in cisplatin resistant ovarian cancer
CIHR · 2025 · Supervisor
- $845,326
Single-stranded DNA generation during UV-induced replicative stress in skin cancer
CIHR · 2024 · Nominated PI
- $929,475
Replicative stress as a primary determinant of chemotherapeutic outcome in ovarian cancer
CIHR · 2021 · Co-investigator
17 publications.
Focus on numbers - characterizing protein accumulation at DNA double-strand breaks.
Modica G, Roy J, Godin AG, Wurtele H, Costantino S
Functional studies in yeast confirm the pathogenicity of a new GINS3 Meier-Gorlin syndrome variant.
Mehrjoo Y, Campeau PM, Al Abdi L, Aldowaish A, Abouyousef O, Alkuraya FS, Codina-Solà M, Cueto-González AM, Wurtele H
MNDA, a PYHIN factor involved in transcriptional regulation and apoptosis control in leukocytes.
Bottardi S, Layne T, Ramòn AC, Quansah N, Wurtele H, Affar EB, Milot E
A genome-wide screen reveals that Dyrk1A kinase promotes nucleotide excision repair by preventing aberrant overexpression of cyclin D1 and p21.
Bélanger F, Roussel C, Sawchyn C, St-Hilaire E, Gezzar-Dandashi S, Kimenyi Ishimwe AB, Mallette FA, Wurtele H, Drobetsky E
Persistent Acetylation of Histone H3 Lysine 56 Compromises the Activity of DNA Replication Origins.
Tremblay R, Mehrjoo Y, Ahmed O, Simoneau A, McQuaid ME, Affar EB, Nislow C, Giaever G, Wurtele H
Hypomorphic GINS3 variants alter DNA replication and cause Meier-Gorlin syndrome.
McQuaid ME, Ahmed K, Tran S, Rousseau J, Shaheen R, Kernohan KD, Yuki KE, Grover P, Dreseris ES, Ahmed S, Dupuis L, Stimec J, Shago M, Al-Hassnan ZN, Tremblay R, Maass PG, Wilson MD, Grunebaum E, Boycott KM, Boisvert FM, Maddirevula S, Faqeih EA, Almanjomi F, Khan ZU, Alkuraya FS, Campeau PM, Kannu P, Campos EI, Wurtele H
Chromatin dynamics and DNA replication roadblocks.
Hammond-Martel I, Verreault A, Wurtele H
A Novel Sulfonyl-Based Small Molecule Exhibiting Anti-cancer Properties.
El-Kadiry AE, Abusarah J, Cui YE, El-Hachem N, Hammond-Martel I, Wurtele H, Thomas S, Ahmadi M, Balood M, Talbot S, Rafei M
Opto-magnetic capture of individual cells based on visual phenotypes.
Binan L, Bélanger F, Uriarte M, Lemay JF, Pelletier De Koninck JC, Roy J, Affar EB, Drobetsky E, Wurtele H, Costantino S
Replication Protein A Availability during DNA Replication Stress Is a Major Determinant of Cisplatin Resistance in Ovarian Cancer Cells.
Bélanger F, Fortier E, Dubé M, Lemay JF, Buisson R, Masson JY, Elsherbiny A, Costantino S, Carmona E, Mes-Masson AM, Wurtele H, Drobetsky E
Replication protein A availability in cisplatin resistant ovarian cancer
Principal investigators: Alkhaldi, Sarah
Keywords: Ics Travel Awards
Single-stranded DNA generation during UV-induced replicative stress in skin cancer
Principal investigators: Wurtele, Hugo
Keywords: Biochemistry; Cell Biology; Crispr-Cas9 Screening; Dna Repair; Dna Replication; Gene Expression Profiling; Genetics; Mutagenesis; Skin Cancer; Uv-Induced Replicative Stress
Replicative stress as a primary determinant of chemotherapeutic outcome in ovarian cancer
Principal investigators: Drobetsky, Elliot A
Keywords: Chemoresistance; Dna Damage Signaling; Dna Double Strand Break Repair; Dna Replication Stress; Nucleotide Excision Repair; Ovarian Cancer
Influence of Ikaros on treatment response in Acute Lymphoblastic Leukemia
Principal investigators: Milot, Eric
Keywords: Acute Lymphoblastic Leukemia; Dna-Rna Hybrids; Genomic Instability; Ikaros; Protein Interactome; R-Chip-Seq
A system for automated high-content screening and laser manipulation of single cells.
Principal investigators: Costantino, Santiago
Modifications of newly synthesized histones and the cellular response to DNA replication stress
Principal investigators: Wurtele, Hugo
Modifications of newly synthesized histones and the cellular response to DNA replication stress
Principal investigators: Wurtele, Hugo
Modulation of UV damage repair by replicative stress-induced RPA exhaustion during skin cancer development
Principal investigators: Wurtele, Hugo
Keywords: Dna Repair; Dna Replication; Genetic Determinants Of Cancer; Melanoma; Mutagenesis; Nucleotide Excision Repair
Identification of novel replication stress response modulators through genome-wide CRISPR/Cas9 screens.
Principal investigators: Lemay, Jean-François
Keywords: Cancer; Cellular Biology; Crispr/Cas9; Dna Damage; Dna Repair; Flow Cytometry; Genome Integrity; High-Troughput Screening; Replication Stress; Synthetic Lethality
A microcalorimetry system to define the biochemical parameters of molecular interactions
Principal investigators: Affar, ElBachir
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Moutih Rafei and Moutih Rafei: 51 shared papers
- Santiago Costantino and Santiago Costantino: 46 shared papers
- Hugo Wurtele and Alain Verreault: 4 shared papers
- Hugo Wurtele and Elliot Drobetsky: 4 shared papers
- Alain Verreault and Pierre Thibault: 4 shared papers
- Hugo Wurtele and Santiago Costantino: 3 shared papers
- Hugo Wurtele and Santiago Costantino: 3 shared papers
- Hugo Wurtele and Adnane Sellam: 3 shared papers
- Hugo Wurtele and Corey Nislow: 2 shared papers
- Hugo Wurtele and Pierre Thibault: 2 shared papers
- Hugo Wurtele and Eric Milot: 1 shared paper
- Hugo Wurtele and Jean-Yves Masson: 1 shared paper
- Hugo Wurtele and Peter Kannu: 1 shared paper
- Hugo Wurtele and Moutih Rafei: 1 shared paper
- Hugo Wurtele and Moutih Rafei: 1 shared paper
- Alain Verreault and Santiago Costantino: 1 shared paper
- Alain Verreault and Santiago Costantino: 1 shared paper
- Eric Milot and Elliot Drobetsky: 1 shared paper
- Santiago Costantino and Elliot Drobetsky: 1 shared paper
- Santiago Costantino and Pierre Thibault: 1 shared paper
- Jean-Yves Masson and Elliot Drobetsky: 1 shared paper
- Corey Nislow and Adnane Sellam: 1 shared paper
- Medicine
- Centre de recherche
- Institut de recherche en immunologie et cancer
- Medical Microbiology and Infectious Diseases
- Engineering Physics
- Microbiology
- Physiology and Pharmacology
- Other
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Alain Verreault
Institut de recherche en immunologie et cancer
4 shared papers, latest 2021
Elliot Drobetsky
Medicine
4 shared papers, latest 2023
Santiago Costantino
Faculty
3 shared papers, latest 2025
Santiago Costantino
Engineering Physics
3 shared papers, latest 2025
Adnane Sellam
Medical Microbiology and Infectious Diseases
3 shared papers, latest 2017
Pierre Thibault
Faculty
2 shared papers, latest 2015
Corey Nislow
Faculty
2 shared papers, latest 2023
Jean-Yves Masson
Faculty
1 shared papers, latest 2018
Peter Kannu
Developmental and Stem Cell Biology
1 shared papers, latest 2022
Moutih Rafei
Physiology and Pharmacology
1 shared papers, latest 2020
Moutih Rafei
Microbiology
1 shared papers, latest 2020
Eric Milot
Medicine
1 shared papers, latest 2024
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