Faculty profile
Paul Jolicoeur
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Read how they describe their research on their Université de Montréal profile.
Latest papers
HIV Nef-mediated WAVE2-ARP2/3 inhibition underlies CD4+ T-cell lamellipodial abnormalities and immune dysfunction.
mBio · 2026
HIV Nef disrupts Lck signaling by inducing aberrant phosphorylation of its substrates.
ImmunoHorizons · 2025 · senior author
Nef-mediated ARP2/3 inhibition drives CD4+ T cell dysfunction and dysregulated immunity in HIV progressors 2658
The Journal of Immunology · 2025
Latest funding
- $100,000
Molecular study of HIV-induced immunodeficiency
CIHR · 2011 · Nominated PI
Developing animal models of mycobacteria tuberculosis infection and reactivation in AIDS
CIHR · 2010 · Nominated PI
- $678,180
Study of the cellular and molecular mechanisms of HIV associated nephropathy (HIVAN)
CIHR · 2009 · Nominated PI
From the 150 most recent of 199 publications.
HIV Nef-mediated WAVE2-ARP2/3 inhibition underlies CD4+ T-cell lamellipodial abnormalities and immune dysfunction.
Dunn DC, Crater JM, Del Río Estrada PM, Malgady JM, Haas G, Klain W, Torres-Ruiz MF, Luna-Villalobos YA, González-Navarro M, Kang C, Kovacs C, Ávila-Ríos S, Lee B, Jolicoeur P, Nixon DF, Furler O'Brien RL
HIV Nef disrupts Lck signaling by inducing aberrant phosphorylation of its substrates.
Guertin J, Chrobak P, Meunier C, Thomson CM, Hanna Z, Jolicoeur P
Nef-mediated ARP2/3 inhibition drives CD4+ T cell dysfunction and dysregulated immunity in HIV progressors 2658
Jeffrey M. Malgady, Daniel C. Dunn, Bruno C. Casado Lima, Jacqueline M. Crater, Perla M. Del Río Estrada, Fernanda Torres-Ruiz, Yara Andrea Luna-Villalobos, Mauricio González-Navarro, Colin M Kovacs, Chris Kang, Paul Jolicoeur, Santiago Ávila‐Ríos, Douglas F. Nixon, Robert L. Furler O’Brien
Spatial characterization of immunosenescence within HIV infected lymph nodes 2718
Daniel C. Dunn, L. Iñiguez, Perla M. Del Río Estrada, Kevin L. Newcombe, Jeffrey M. Malgady, Jacqueline M. Crater, Bruno Lima, Fernanda Torres-Ruiz, Yara Andrea Luna-Villalobos, Mauricio González-Navarro, Chris Kang, Colin M Kovacs, Santiago Ávila‐Ríos, Paul Jolicoeur, Douglas F. Nixon, Robert L. Furler O’Brien
PP1.2 – 00165 Inhibition of ARP2/3 by HIV Nef Leads to Impaired CD4+ T Cell Function & Dysregulation of Immunity within Progressors but not all HIV Controllers
Daniel C. Dunn, Jeffrey M. Malgady, Bruno Lima, Jacqueline M. Crater, Perla M. Del Río Estrada, Fernanda Torres-Ruiz, Yara Andrea Luna-Villalobos, M. González-Navarro, Colin M Kovacs, Chunsheng Kang, Donald E. Mullins, Paul Jolicoeur, S. Ávila-Ríos, Douglas F. Nixon, Robert L. Furler O’Brien
NEF-Induced HIV-Associated Nephropathy Through HCK/LYN Tyrosine Kinases.
Hu C, Priceputu E, Cool M, Chrobak P, Bouchard N, Forestier C, Lowell CA, Bénichou S, Hanna Z, Royal V, Jolicoeur P
HIV-1 Nef Induces Hck/Lyn-Dependent Expansion of Myeloid-Derived Suppressor Cells Associated with Elevated Interleukin-17/G-CSF Levels.
Priceputu E, Cool M, Bouchard N, Caceres-Cortes JR, Lowell CA, Hanna Z, Jolicoeur P
HIV-Nef Protein Persists in the Lungs of Aviremic Patients with HIV and Induces Endothelial Cell Death.
Chelvanambi S, Bogatcheva NV, Bednorz M, Agarwal S, Maier B, Alves NJ, Li W, Syed F, Saber MM, Dahl N, Lu H, Day RB, Smith P, Jolicoeur P, Yu Q, Dhillon NK, Weissmann N, Twigg Iii HL, Clauss M
HIV-Nef Protein Transfer to Endothelial Cells Requires Rac1 Activation and Leads to Endothelial Dysfunction Implications for Statin Treatment in HIV Patients.
Chelvanambi S, Gupta SK, Chen X, Ellis BW, Maier BF, Colbert TM, Kuriakose J, Zorlutuna P, Jolicoeur P, Obukhov AG, Clauss M
HIV-Nef Protein Persists in Bronchoalveolar Lavage Derived Extracellular Vesicles of HIV Patients on ART and Induces EMAPII Amplified Endothelial Cell Apoptosis Resulting in Pulmonary Vascular Pathologies Like Pulmonary Hypertension
Sarvesh Chelvanambi, Natalia V. Bogatcheva, Paul Jolicoeur, Homer L. Twigg, Matthias A. Clauss
Molecular study of HIV-induced immunodeficiency
Principal investigators: Jolicoeur, Paul
Keywords: Aids; Animal Model; Hiv-1; Transgenic Mice
Developing animal models of mycobacteria tuberculosis infection and reactivation in AIDS
Principal investigators: Jolicoeur, Paul
Keywords: Aids; Hiv; Transgenic Mice; Tuberculosis
Study of the cellular and molecular mechanisms of HIV associated nephropathy (HIVAN)
Principal investigators: Jolicoeur, Paul
Keywords: Aids; Animal Model; Focal Segmental Glomerulosclerosis; Hiv-1; Transgenic Mice
Dissecting the mechanisms of protection by attenuated Nef-deleted HIV vaccine
Principal investigators: Jolicoeur, Paul
Keywords: Aids; Hiv; Transgenic Mice; Vaccine
DNA Microarrays and protein mass spectrometry for biomedical discovery
Principal investigators: Jolicoeur, Paul
Keywords: Retrovirus, functional genomics, AIDS, cancer, neurodegenerative diseases.
Nouveaux modèles expérimentaux de pathologies humaines : évaluations cellulaire et physiologique (Génomique fonctionnelle chez la souris)
Principal investigators: Guindon, Yvan
Keywords: Modèles petits animaux, pathologies humaines, cancer, immunodéficiences, maladies cardiovasculaires, troubles neurologiques, développement, modalités thérapeutiques
Canadian Network for Vaccines and Immunotherapeutics of Cancer and Chronic Viral Diseases (CANVAC)
Principal investigators: Sekaly, RafickPierre
Animaleries
Principal investigators: Guindon, Yvan
Keywords: Modèles animaux de pathologie, Régulation génique, Inactivation génique, Transgenèse, Biologie du développement, SIDA, Cancer, Maladies cardio-vasculaires
Infrastructures pour la recherche sur l'infection au VIH: Doter le Québec et le Canada d'infrastructures pour un vaccin et des thérapies contre le VIH et l'hépatite C
Principal investigators: Sékaly, Rafick
Keywords: VIH, Hépatite C, Thérapeutique, Cohortes, Épidémiologie, Immunologie, Virologie, Cytoflourimétrie, Confinement
Infrastructure d'histologie et d'imagerie
Principal investigators: Guindon, Yvan
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- James Kronstad and Jim Kronstad: 255 shared papers
- Éric Rassart and Paul Jolicoeur: 30 shared papers
- Luc DesGroseillers and Paul Jolicoeur: 17 shared papers
- Céline Fiset and Judith Brouillette: 11 shared papers
- Luc DesGroseillers and Éric Rassart: 11 shared papers
- Scott Grandy and Céline Fiset: 10 shared papers
- Tak Mak and Mathieu Lupien: 8 shared papers
- Louis de Repentigny and Paul Jolicoeur: 8 shared papers
- Richard Villemur and Paul Jolicoeur: 5 shared papers
- Xiaoyan Jiang and Paul Jolicoeur: 4 shared papers
- Éric Rassart and Richard Villemur: 4 shared papers
- Scott Grandy and Judith Brouillette: 3 shared papers
- Christopher Gravel and Paul Jolicoeur: 3 shared papers
- Paul Jolicoeur and Johanne Poudrier: 3 shared papers
- Tak Mak and Paul Jolicoeur: 2 shared papers
- Tarik Möröy and Paul Jolicoeur: 2 shared papers
- Mathieu Lupien and Paul Jolicoeur: 2 shared papers
- Scott Grandy and Paul Jolicoeur: 2 shared papers
- Caroline Hoemann and Paul Jolicoeur: 2 shared papers
- Céline Fiset and Paul Jolicoeur: 2 shared papers
- Luc DesGroseillers and Richard Villemur: 2 shared papers
- Louise Bouchard and Paul Jolicoeur: 2 shared papers
- Mir Rahim and Paul Jolicoeur: 2 shared papers
- Judith Brouillette and Paul Jolicoeur: 2 shared papers
- Louis de Repentigny and Louis Gaboury: 2 shared papers
- Paul Jolicoeur and Louis Gaboury: 2 shared papers
- Guillaume Pare and Paul Jolicoeur: 1 shared paper
- Jacques Drouin and Paul Jolicoeur: 1 shared paper
- Frederic Charron and Paul Jolicoeur: 1 shared paper
- Tak Mak and Johanne Poudrier: 1 shared paper
- Tarik Möröy and Louis Gaboury: 1 shared paper
- Mathieu Lupien and Carlos Morales: 1 shared paper
- James Kronstad and Louis de Repentigny: 1 shared paper
- James Kronstad and Paul Jolicoeur: 1 shared paper
- Alain Nepveu and Paul Jolicoeur: 1 shared paper
- Jim Kronstad and Louis de Repentigny: 1 shared paper
- Jim Kronstad and Paul Jolicoeur: 1 shared paper
- Carlos Morales and Paul Jolicoeur: 1 shared paper
- Department of Microbiology, Infectious Diseases and Immunology
- Department of Biochemistry and Molecular Medicine
- Department of Biological Sciences
- Environmental Microbiology
- Terry Fox Laboratory
- School of Epidemiology and Public Health
- Chemical Engineering
- Other
Co-authors at Université de Montréal, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Éric Rassart
Department of Biological Sciences
30 shared papers, latest 1992
Luc DesGroseillers
Department of Biochemistry and Molecular Medicine
17 shared papers, latest 1991
Louis de Repentigny
Department of Microbiology, Infectious Diseases and Immunology
8 shared papers, latest 2015
Richard Villemur
Environmental Microbiology
5 shared papers, latest 1987
Xiaoyan Jiang
Terry Fox Laboratory
4 shared papers, latest 2002
Johanne Poudrier
Department of Microbiology, Infectious Diseases and Immunology
3 shared papers, latest 2014
Guy Lemay
Department of Microbiology, Infectious Diseases and Immunology
3 shared papers, latest 2016
Christopher Gravel
School of Epidemiology and Public Health
3 shared papers, latest 1993
Louis Gaboury
Department of Pathology and Cell Biology
2 shared papers, latest 2014
Judith Brouillette
Faculty
2 shared papers, latest 2009
Tarik Möröy
Montreal Clinical Research Institute
2 shared papers, latest 2009
Mathieu Lupien
Department of Medical Biophysics
2 shared papers, latest 2006
Caroline Hoemann
Chemical Engineering
2 shared papers, latest 2000
Céline Fiset
Montreal Heart Institute
2 shared papers, latest 2009
Mir Rahim
Department of Biomedical Sciences
2 shared papers, latest 2013
Scott Grandy
Kinesiology
2 shared papers, latest 2009
Louise Bouchard
Sociological and Anthropological Studies
2 shared papers, latest 1998
Tak Mak
Department of Immunology
2 shared papers, latest 2005
Virginie Royal
Department of Pathology and Cell Biology
1 shared papers, latest 2023
Peter Watson
Faculty
1 shared papers, latest 2002
Jacques Drouin
Department of Biochemistry and Molecular Medicine
1 shared papers, latest 1975
Frederic Charron
Medicine
1 shared papers, latest 1998
James Kronstad
Michael Smith Laboratories
1 shared papers, latest 2013
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.