Faculty profile
Robert Dumaine
Back to facultyThis profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Sherbrooke directory, so their courses may be missing. Find their university profile.
Latest papers
A Metabolically Stable Apelin-13 Analog Acting as a Potent ITo Potassium Current Blocker with Potential Benefits for Brugada Syndrome.
International journal of molecular sciences · 2025 · senior author
Epilepsy-Induced High Affinity Blockade of the Cardiac Sodium Current INa by Lamotrigine; A Potential for Acquired Arrythmias.
Pharmaceuticals (Basel, Switzerland) · 2022 · senior author
The neuronal potassium current IA is a potential target for pain during chronic inflammation.
Physiological reports · 2021 · senior author
Latest funding
- $144,000
Cellular mechanisms controlling the expression and activity of sodium channels
NSERC · 2021 · Principal investigator
- $707,626
Exploiting ELABELA and analogues to Protect from Septic Shock
CIHR · 2018 · Co-investigator
- $100,000
Exploiting ELABELA and Analogues to Protect from Septic Shock
CIHR · 2017 · Co-investigator
24 publications.
A Metabolically Stable Apelin-13 Analog Acting as a Potent ITo Potassium Current Blocker with Potential Benefits for Brugada Syndrome.
Contreras Vite JA, Tiffinger A, Théroux L, Morin N, Auger-Messier M, Boudreault PL, Sarret P, Lesur O, Dumaine R
Epilepsy-Induced High Affinity Blockade of the Cardiac Sodium Current INa by Lamotrigine; A Potential for Acquired Arrythmias.
Contreras Vite JA, Vega Valle C, Biekeu Mbem H, Boivin SM, Dumaine R
The neuronal potassium current IA is a potential target for pain during chronic inflammation.
Biet M, Dansereau MA, Sarret P, Dumaine R
In utero exposure to nicotine abolishes the postnatal response of the cardiac sodium current to isoproterenol in newborn rabbit atrium.
Biet M, Ton AT, Delabre JF, Morin N, Dumaine R
Apelin-13 Regulates Vasopressin-Induced Aquaporin-2 Expression and Trafficking in Kidney Collecting Duct Cells.
Boulkeroua C, Ayari H, Khalfaoui T, Lafrance M, Besserer-Offroy É, Ekindi N, Sabbagh R, Dumaine R, Lesur O, Sarret P, Chraibi A
A novel three base-pair deletion in domain two of the cardiac sodium channel causes Brugada syndrome.
Tan BY, Wang L, Uttamchandani M, Barajas-Martinez H, Dumaine R, Morin N, Ching CK, Ho KL, Chong DTT, Chow W, Yap EPH, Moochhala S, Hu D, Yong RYY, Teo WS
The hypotensive effect of activated apelin receptor is correlated with β-arrestin recruitment.
Besserer-Offroy É, Bérubé P, Côté J, Murza A, Longpré JM, Dumaine R, Lesur O, Auger-Messier M, Leduc R, Marsault É, Sarret P
A Systematic Exploration of Macrocyclization in Apelin-13: Impact on Binding, Signaling, Stability, and Cardiovascular Effects.
Trân K, Murza A, Sainsily X, Coquerel D, Côté J, Belleville K, Haroune L, Longpré JM, Dumaine R, Salvail D, Lesur O, Auger-Messier M, Sarret P, Marsault É
In-utero exposure to nicotine alters the development of the rabbit cardiac conduction system and provides a potential mechanism for sudden infant death syndrome.
Ton AT, Biet M, Delabre JF, Morin N, Dumaine R
ELABELA Improves Cardio-Renal Outcome in Fatal Experimental Septic Shock.
Coquerel D, Chagnon F, Sainsily X, Dumont L, Murza A, Côté J, Dumaine R, Sarret P, Marsault É, Salvail D, Auger-Messier M, Lesur O
Cellular mechanisms controlling the expression and activity of sodium channels
Principal investigators: Dumaine, Robert
Keywords: patch clamp; electrophysiology; gene expression; ion channels
Exploiting ELABELA and analogues to Protect from Septic Shock
Principal investigators: Lesur, Olivier J; Marsault, Eric
Keywords: Animal Models; Apelin Receptor; Apelins; Biased Signalling; Cardiovascular Dysfunction; Drug Discovery; Elabela; G Protein-Coupled Receptors; Renal Dysfunction; Septic Shock
Exploiting ELABELA and Analogues to Protect from Septic Shock
Principal investigators: Lesur, Olivier J; Marsault, Eric
Keywords: Animal Models; Apelin Receptor; Apelins; Biased Signaling; Cardiovascular Dysfunction; Drug Discovery; Elabela; G Protein-Coupled Receptors; Kidney Dysfunction; Septic Shock
The Apelin Receptor as a Target for Heart Failure
Principal investigators: Marsault, Eric; Auger-Messier, Mannix
Keywords: Animal Models; Apelin; Apj Receptor; Biased Signaling; Drug Discovery; G Protein-Coupled Receptor; Heart Failure; Macrocycles; Molecular Dynamics; Peptidomimetic
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Richard Leduc and Pierre-Luc Boudreault: 20 shared papers
- Philippe Sarret and Olivier Lesur: 18 shared papers
- Philippe Sarret and Mannix Auger-Messier: 16 shared papers
- Mannix Auger-Messier and Olivier Lesur: 16 shared papers
- Philippe Sarret and Pierre-Luc Boudreault: 15 shared papers
- Philippe Sarret and Robert Dumaine: 13 shared papers
- Philippe Sarret and Richard Leduc: 11 shared papers
- Olivier Lesur and Robert Dumaine: 11 shared papers
- Mannix Auger-Messier and Richard Leduc: 9 shared papers
- Mannix Auger-Messier and Robert Dumaine: 8 shared papers
- Eric Marsault and Pierre-Luc Boudreault: 8 shared papers
- Philippe Sarret and Michel Grandbois: 7 shared papers
- Philippe Sarret and Eric Marsault: 6 shared papers
- Richard Leduc and Eric Marsault: 6 shared papers
- Pierre-Luc Boudreault and Michel Grandbois: 6 shared papers
- Richard Leduc and Robert Dumaine: 4 shared papers
- Richard Leduc and Michel Grandbois: 2 shared papers
- Eric Marsault and Robert Dumaine: 1 shared paper
- Pierre-Luc Boudreault and Robert Dumaine: 1 shared paper
- Michel Grandbois and Robert Dumaine: 1 shared paper
- Pharmacologie
- Pharmacologie et Physiologie
- Obstétrique et gynécologie
- Médecine
- Médecine/cardiologie
- Physiology and Pharmacology
- Pharmacologie-Physiologie
Co-authors at Université de Sherbrooke, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Philippe Sarret
Obstétrique et gynécologie
13 shared papers, latest 2025
Olivier Lesur
Médecine
11 shared papers, latest 2025
Mannix Auger-Messier
Médecine/cardiologie
8 shared papers, latest 2025
Richard Leduc
Physiology and Pharmacology
4 shared papers, latest 2018
Eric Marsault
Pharmacologie
1 shared papers, latest 2017
Pierre-Luc Boudreault
Pharmacologie
1 shared papers, latest 2025
Michel Grandbois
Pharmacologie-Physiologie
1 shared papers, latest 2013
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