Faculty profile

Andrew Holt

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Associate ProfessorPsychiatry DeptUniversity of Alberta

Andrew Holt

Associate Professor

Psychiatry Dept

Faculty of Medicine & Dentistry

University of Alberta

Edmonton, Alberta, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
6 publications in the last five years, latest in 2025.
Principal investigator on 2 research grants (1 CFI, 1 CIHR), most recently in 2009.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

1,211

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Roles and appointments

Graduate Program Director, Faculty of Medicine and Dentistry - Psychiatry Dept

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Alberta profile.

Latest papers

Immunometabolism perturbations in post-COVID-19 condition: interleukin-6 and monoamine oxidase interactions drive neuropsychiatric syndromes.
Brain, behavior, and immunity · 2025
Variation in the osmotic characteristics of aging red blood cells: insights for cryopreservation optimization
Cytotherapy · 2025
The prescriber's guide to classic MAO inhibitors (phenelzine, tranylcypromine, isocarboxazid) for treatment-resistant depression.
CNS spectrums · 2023

All 29 publications

Latest funding

Clozapine toxicity mechanisms and mitigation strategies
CIHR · 2023 · Co-investigator
$707,625
Molecular enzymology laboratory
CFI · 2009 · Principal investigator
$120,321
Novel aspects of amine oxidase catalysis: mechanisms, consequences and therapeutic targets
CIHR · 2008 · Nominated PI
$466,392

All 3 grants and awards

29 publications.

Immunometabolism perturbations in post-COVID-19 condition: interleukin-6 and monoamine oxidase interactions drive neuropsychiatric syndromes.

Ogando NS, Elaish M, Mahabadi HM, Langdon KD, Das SK, Joseph JT, Fujiwara E, Holt A, Kaur K, Branton W, Gheblawi M, Lacy P, Oudit GY, Hobman TC, Lam GY, Power C

Brain, behavior, and immunity20254 citations

DOI: 10.1016/j.bbi.2025.07.002 PMID: 40619111

Variation in the osmotic characteristics of aging red blood cells: insights for cryopreservation optimization

Sanaz Hemmatibardehshahi, Mackenzie Brandon‐Coatham, Andrew Holt, Jason P. Acker

Cytotherapy20253 citationsOpen Access

DOI: 10.1016/j.jcyt.2025.01.010 PMID: 39955662

The prescriber's guide to classic MAO inhibitors (phenelzine, tranylcypromine, isocarboxazid) for treatment-resistant depression.

Van den Eynde V, Abdelmoemin WR, Abraham MM, Amsterdam JD, Anderson IM, Andrade C, Baker GB, Beekman ATF, Berk M, Birkenhäger TK, Blackwell BB, Blier P, Blom MBJ, Bodkin AJ, Cattaneo CI, Dantz B, Davidson J, Dunlop BW, Estévez RF, Feinberg SS, Finberg JPM, Fochtmann LJ, Gotlib D, Holt A, Insel TR, Larsen JK, Mago R, Menkes DB, Meyer JM, Nutt DJ, Parker G, Rego MD, Richelson E, Ruhé HG, Sáiz-Ruiz J, Stahl SM, Steele T, Thase ME, Ulrich S, van Balkom AJLM, Vieta E, Whyte I, Young AH, Gillman PK

CNS spectrums202375 citationsOpen Access

DOI: 10.1017/s1092852922000906 PMID: 35837681

Radiochemical Assay of Monoamine Oxidase Activity.

Holt A

Methods in molecular biology (Clifton, N.J.)2023First author

DOI: 10.1007/978-1-0716-2643-6_5 PMID: 36169855

Conventional Receptor Radioligand Binding Techniques Applied to the Study of Monoamine Oxidase.

Holt A

Methods in molecular biology (Clifton, N.J.)2023First author

DOI: 10.1007/978-1-0716-2643-6_7 PMID: 36169857

Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine.

Matveychuk D, MacKenzie EM, Kumpula D, Song MS, Holt A, Kar S, Todd KG, Wood PL, Baker GB

Cellular and molecular neurobiology202234 citationsOpen Access

DOI: 10.1007/s10571-021-01078-3 PMID: 33839994

Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine.

Baker G, Matveychuk D, MacKenzie EM, Holt A, Wang Y, Kar S

Chemico-biological interactions201934 citationsOpen Access

DOI: 10.1016/j.cbi.2019.03.003 PMID: 30857888

On the practical aspects of characterising monoamine oxidase inhibition in vitro.

Holt A

Journal of neural transmission (Vienna, Austria : 1996)2018First author

DOI: 10.1007/s00702-018-1943-8 PMID: 30374594

Disease-modifying effects of ganglioside GM1 in Huntington's disease models.

Alpaugh M, Galleguillos D, Forero J, Morales LC, Lackey SW, Kar P, Di Pardo A, Holt A, Kerr BJ, Todd KG, Baker GB, Fouad K, Sipione S

EMBO molecular medicine201780 citationsOpen Access

DOI: 10.15252/emmm.201707763 PMID: 28993428

ADAM, a hands-on patient simulator for teaching principles of drug disposition and compartmental pharmacokinetics.

Zuna I, Holt A

British journal of clinical pharmacology2017Senior author

DOI: 10.1111/bcp.13357 PMID: 28666308

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Andrew Holt

Research

Latest papers

Latest funding

Immunometabolism perturbations in post-COVID-19 condition: interleukin-6 and monoamine oxidase interactions drive neuropsychiatric syndromes.

Variation in the osmotic characteristics of aging red blood cells: insights for cryopreservation optimization

The prescriber's guide to classic MAO inhibitors (phenelzine, tranylcypromine, isocarboxazid) for treatment-resistant depression.

Radiochemical Assay of Monoamine Oxidase Activity.

Conventional Receptor Radioligand Binding Techniques Applied to the Study of Monoamine Oxidase.

Overview of the Neuroprotective Effects of the MAO-Inhibiting Antidepressant Phenelzine.

Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine.

On the practical aspects of characterising monoamine oxidase inhibition in vitro.

Disease-modifying effects of ganglioside GM1 in Huntington's disease models.

ADAM, a hands-on patient simulator for teaching principles of drug disposition and compartmental pharmacokinetics.

Clozapine toxicity mechanisms and mitigation strategies

Molecular enzymology laboratory

Novel aspects of amine oxidase catalysis: mechanisms, consequences and therapeutic targets

Frequent collaborators

Peter Light

Richard Schulz

S Kar

Kathryn Todd

Satyabrata Kar

Jonathan Martin

Frances Plane

Jason Acker

Charles Holmes

Karim Fouad

Esther Fujiwara

Kay Rittenbach

Bradley Kerr

Barbara Ballermann

Simonetta Sipione

Grace Lam

Christopher Power

Paige Lacy

Melanie Alpaugh

Mahmoud Ali

Pierre Blier

Michael James