This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.
Research
Latest papers
The emerging roles of ITM2A: At the molecular crossroads of development and pathogenesis.
iScience · 2026
Regulation of the PKD2 channel function and associated disease phenotypes by RASSF4.
Communications biology · 2026
Localized phosphoinositide metabolism regulates STIM1/ORAI1 fast inactivation.
iScience · 2026 · senior author
Latest funding
- $348,000
Elucidating the molecular mechanisms of regulation of cellular stress sensors
NSERC · 2019 · Principal investigator
- $970,785
Molecular mechanisms that promote cardiac cell survival and heart health
CIHR · 2019 · Nominated PI
- $459,000
A role of calcium signalling in cholesterol metabolism
CIHR · 2016 · Nominated PI
137 publications.
The emerging roles of ITM2A: At the molecular crossroads of development and pathogenesis.
Deng X, Wang Y, Yang L, Wu K, Qin W, Ali DW, Michalak M, Tang J, Zhou C, Chen XZ
Regulation of the PKD2 channel function and associated disease phenotypes by RASSF4.
Tian R, Fang W, Yuan W, Li S, Wu Y, Dong X, Liu W, Kong J, Deng X, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Ali DW, Michalak M, Zhou C, Tang J, Chen XZ
Localized phosphoinositide metabolism regulates STIM1/ORAI1 fast inactivation.
Dai N, Lamothe SM, Groenendyk J, Touret N, Kurata HT, Michalak M
Endoplasmic reticulum stress, calcium homeostasis, and the aging heart.
Quest I, Michalak M
Accumulation of succinate in the blood is a potential early indicator of metabolic dysfunction-associated steatotic liver disease (MASLD).
Chalifoux O, Dagostino C, Li M, Trezza S, Grayson C, De Sa Tavares Russo M, Avizonis DZ, Michalak M, Agellon LB, Mailloux RJ
The Dual Role of RASSF4 in Tumorigenesis: Mechanisms and Epigenetic Targeting Strategies.
Tian R, Wu Y, Yuan W, Tian L, Zhang R, Lyu H, Xiao S, Guo D, Zhang Q, Ali DW, Michalak M, Zhou C, Tang J, Chen XZ
The polyphenols phloretin and quercetin are potent horseradish peroxidase (HRP) inhibitors.
Faerman B, Chalifoux O, Michalak M, Agellon LB, Mailloux RJ
Myotubularin related protein 7, a novel STIM1 binding protein.
Dai N, Groenendyk J, Michalak M
MitoSNO inhibits mitochondrial hydrogen peroxide generation by α-ketoglutarate dehydrogenase.
Chalifoux O, Sterman S, Faerman B, Li M, Trezza S, Michalak M, Agellon LB, Mailloux RJ
Selective regulation of aspartyl intramembrane protease activity by calnexin.
Contreras W, Groenendyk J, Gentzel M, Schönberg PY, Buchholz F, Michalak M, Schröder B, Mentrup T
Elucidating the molecular mechanisms of regulation of cellular stress sensors
Principal investigators: Michalak, Marek
Keywords: calcium signaling; endoplasmic reticulum; endoplasmic reticulum resident proteins; molecular chaperones; molecular interactions; protein folding; stress coping responses; stress sensors; stress signaling; unfolded protein response
Molecular mechanisms that promote cardiac cell survival and heart health
Principal investigators: Michalak, Marek S; Agellon, Luis B
Keywords: Calcium Signaling; Endoplasmic Reticulum Stress; Fibrosis; Heart Failure; Molecular Chaperone; Proteostasis; Sarcoplasmic Reticulum; Stress Responses; Stress Sensor; Unfolded Protein Response
A role of calcium signalling in cholesterol metabolism
Principal investigators: Michalak, Marek S
Keywords: Calcium Homeostasis; Calreticulin; Cholesterol; Endoplasmic Reticulum; Orai1; Srebp; Stim1; Store-Operated Calcium Entry
Endoplasmic Reticulum Function in Heart Health
Principal investigators: Michalak, Marek S
Keywords: Ca Homeostasis; Endoplasmic Retiulum Stress; Energy Metabolism; Er Homeostasis; Heart Failure; Protein Folding; Transgenic Animals
Activation of SREBP2 activity in the absence of calreticulin
Principal investigators: Wang, Wen-An
Keywords: Calcium; Calreticulin; Endoplasmic Reticulum; Lipid Metabolism; Protein Folding; Sterol Regulatory Element Binding Protein
Endoplasmic reticulum protein quality control in cardiac physiology and pathology
Principal investigators: Michalak, Marek S
Keywords: Calcium Homeostasis; Calreticulin; Cardiogenesis; Chaperones; Congential Heart Diseases; Endoplasmic Reticulum; Er Stress; Transcription
Regulation of store-operated calcium entry in cancer
Principal investigators: Prins, Daniel
Keywords: Calcium Imaging; Calcium Signaling; Calpain; Cancer Metastasis; Stim1
Cardiac differentiation of embryonic stem cells
Principal investigators: Michalak, Marek S
Keywords: Calcium; Cardiac Differentiation; Chaperones; Embryonic Stem Cells; Endoplasmic Reticulum; Signaling
Quality control in the secretory pathway
Principal investigators: Michalak, Marek S
Keywords: Ca Homeostasis; Calnexin; Calreticulin; Er Quality Control; Protein Folding; Transgenic Animals
Molecular mechanisms of cardiac development
Principal investigators: Michalak, Marek S
Keywords: Calcium Homeostasis; Calreticulin; Cardiogenesis; Chaperones; Congenital Heart Diseases; Endoplasmic Reticulum; Transcription
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Marek Michalak and Xing-Zhen Chen: 28 shared papers
- Jason Dyck and Simon Gosgnach: 4 shared papers
- Marek Michalak and Vilceu Bordignon: 4 shared papers
- Christopher Power and Douglas Zochodne: 3 shared papers
- Christopher Power and Olivier Julien: 3 shared papers
- Evangelos Michelakis and Gopinath Sutendra: 3 shared papers
- Marek Michalak and Douglas Zochodne: 3 shared papers
- Marek Michalak and Nicolas Touret: 3 shared papers
- Nicolas Touret and Olivier Julien: 3 shared papers
- Richard Lehner and Marek Michalak: 2 shared papers
- Christopher Power and Marek Michalak: 2 shared papers
- Marek Michalak and Khaled Barakat: 2 shared papers
- Richard Lehner and Nicolas Touret: 1 shared paper
- Richard Lehner and Simonetta Sipione: 1 shared paper
- David Williams and Marek Michalak: 1 shared paper
- Christopher Power and Simonetta Sipione: 1 shared paper
- Christopher Power and Kathryn Todd: 1 shared paper
- Jason Dyck and Marek Michalak: 1 shared paper
- Jason Dyck and Douglas Zochodne: 1 shared paper
- Jason Dyck and Kathryn Todd: 1 shared paper
- Evangelos Michelakis and Marek Michalak: 1 shared paper
- Evangelos Michelakis and Xing-Zhen Chen: 1 shared paper
- Marek Michalak and Larry Fliegel: 1 shared paper
- Marek Michalak and Simon Gosgnach: 1 shared paper
- Marek Michalak and Gopinath Sutendra: 1 shared paper
- Marek Michalak and Simonetta Sipione: 1 shared paper
- Marek Michalak and Maral Aminpour: 1 shared paper
- Marek Michalak and Olivier Julien: 1 shared paper
- Marek Michalak and Mariusz Klobukowski: 1 shared paper
- Marek Michalak and Kathryn Todd: 1 shared paper
- Marek Michalak and Declan Ali: 1 shared paper
- Larry Fliegel and Nicolas Touret: 1 shared paper
- Simon Gosgnach and Douglas Zochodne: 1 shared paper
- Douglas Zochodne and Xing-Zhen Chen: 1 shared paper
- Xing-Zhen Chen and Declan Ali: 1 shared paper
- Biochemistry
- Medicine
- Physiology
- Pediatrics
- Department of Animal Science
- Medicine/Neurology
- Pharmacy and Pharmaceutical Science, Faculty of
- Other
Co-authors at University of Alberta, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Xing-Zhen Chen
Physiology
28 shared papers, latest 2026
Vilceu Bordignon
Department of Animal Science
4 shared papers, latest 2021
Nicolas Touret
Biochemistry
3 shared papers, latest 2026
Douglas Zochodne
Medicine
3 shared papers, latest 2020
Khaled Barakat
Pharmacy and Pharmaceutical Science, Faculty of
2 shared papers, latest 2018
Richard Lehner
Pediatrics
2 shared papers, latest 2017
Christopher Power
Medicine/Neurology
2 shared papers, latest 2018
Simon Gosgnach
Physiology
1 shared papers, latest 2010
Larry Fliegel
Biochemistry
1 shared papers, latest 2013
Maral Aminpour
Department of Biomedical Engineering
1 shared papers, latest 2023
Olivier Julien
Biochemistry
1 shared papers, latest 2015
Kathryn Todd
Neuroscience/Psychiatry
1 shared papers, latest 2010
Mariusz Klobukowski
Chemistry
1 shared papers, latest 2022
Simonetta Sipione
Pharmacology
1 shared papers, latest 2005
Declan Ali
Biological Sciences
1 shared papers, latest 2020
Gopinath Sutendra
Medicine
1 shared papers, latest 2011
David Williams
Clinical Public Health Division
1 shared papers, latest 2015
Jason Dyck
Pediatrics
1 shared papers, latest 2010
Evangelos Michelakis
Medicine
1 shared papers, latest 2022
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