Faculty profile

Olivier Julien

ResearcherBiochemistryUniversity of Alberta

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.

Olivier Julien

Researcher

Biochemistry

Natural Sciences

University of Alberta

Edmonton, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
28 publications in the last five years, latest in 2026.
Senior (last) author on 8 recent papers, a sign of leading a research group.
Principal investigator on 2 research grants (2 NSERC), most recently in 2018.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Cell death Cell differentiation N-terminomics Protease Proteomics Quantitative mass spectrometry

Latest papers

Structure and Function of a Multi-Megadalton Virus-Like Proteolytic Dodecahedron.
Angewandte Chemie (International ed. in English) · 2026
Caspase-mediated cleavage events hidden by secondary proteolysis during apoptosis.
Protein science : a publication of the Protein Society · 2026
A metabolite extracted from Escherichia coli suppresses tau aggregation.
The Biochemical journal · 2026

All 49 publications

Latest funding

Elucidating the Role of Siglec-G/-10 in the Germinal Centre
CIHR · 2025 · Co-investigator
$983,026
Nano-Flow Liquid Chromatography Equipment for Mass Spectrometry
NSERC · 2025 · Co-investigator
$150,000
Early Life Determinant of T1D Susceptibility
CIHR · 2023 · Co-investigator
$1,048,050

All 12 grants and awards

49 publications.

Structure and Function of a Multi-Megadalton Virus-Like Proteolytic Dodecahedron.

Madej M, Rodríguez-Banqueri A, Mizgalska D, Szmigielski B, Nowakowska Z, Benedyk-Machaczka M, Bzowska M, Mikruta K, Ramírez-Larrota JS, Agunanne C, Julien O, O'Donoghue AJ, Scavenius C, López-Martín M, Marcos E, Koziej Ł, Glatt S, Guerra P, Eckhard U, Potempa J, Gomis-Rüth FX

Angewandte Chemie (International ed. in English)2026

DOI: 10.1002/anie.5597279 PMID: 42723362

Caspase-mediated cleavage events hidden by secondary proteolysis during apoptosis.

Fotouhi F, Gomez-Cardona E, Patel J, Julien O, Fearnhead H

Protein science : a publication of the Protein Society2026

DOI: 10.1002/pro.70724 PMID: 42477898

A metabolite extracted from Escherichia coli suppresses tau aggregation.

Srinivasan M, Patel A, Patel T, Moore J, Gomez-Cardona E, Yarahmady A, Sykes BD, Julien O, Mok SA

The Biochemical journal2026

DOI: 10.1042/bcj20260068 PMID: 41983431

Siglec-G on B cells restrains the germinal center response by controlling T cell help during positive selection.

Enterina JR, Lin SY, Luna-Dulcey L, Sarkar S, Schmidt EN, Jame-Chenarboo Z, Chisholm K, Haq AU, Luo S, Laurent CDS, Ataei T, Giuliani F, Julien O, Macauley MS

bioRxiv : the preprint server for biology2026

DOI: 10.64898/2026.05.06.723371 PMID: 42182281

Expression of progerin enhances disease-related endpoints in a tau seeding reporter cell system.

Han ZZ, Kang SG, Gomez-Cardona E, Wohlgemuth S, Shmeit K, Arce L, Safar JG, Julien O, Westaway D

GeroScience2026

DOI: 10.1007/s11357-025-01737-z PMID: 40660080

Brain and neural cell type proteomics reveal extracellular matrix proteins enriched in progressive multiple sclerosis.

Wang H, Pollock NM, Miranzadeh Mahabadi H, Patel J, Moussa EW, Fernandes JP, Branton WG, Zhang N, Elliott C, Schmitt L, Power C, Julien O

Nature communications2026Senior author

DOI: 10.1038/s41467-025-68118-0 PMID: 41501060

Sacubitril suppresses experimental chronic heart allograft vasculopathy.

Masoud AG, van Baar K, Zhu LF, Julien O, Oudit GY, Murray AG

American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons2026

DOI: 10.1016/j.ajt.2025.08.009 PMID: 40865876

Rhomboid protease GlpG regulates type 1 pili quality control and virulence in pathogenic E. coli.

Lu J, Arutyunova E, Hartley B, Wong J, Chung H, Buchan L, Armstrong H, Phanse S, Young HS, Wine E, Babu M, Chun J, Elhenawy W, Julien O, Lemieux MJ

Nature communications2025

DOI: 10.1038/s41467-025-67697-2 PMID: 41469376

The vaccinia virus protein, C16, promotes the ubiquitylation and relocalization of the antiviral E3 ubiquitin-ligase, TRIM25.

Dong J, Yue Luo S, Smyth S, Melvie G, Julien O, Ingham RJ

Journal of virology2025

DOI: 10.1128/jvi.00898-25 PMID: 40719442

Investigation of CD36 interactome provides insights into multimolecular complexes necessary for anti-angiogenic signalling.

Saini A, Cardona EG, Huang H, Khaing SM, Klein K, Jaqaman K, Julien O, Touret N

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2025.07.15.664851 PMID: 40791553

Elucidating the Role of Siglec-G/-10 in the Germinal Centre

Co-investigatorCIHR2025Project Grant

Principal investigators: Macauley, Matthew S

Keywords: Antibody; Autoimmunity; B Cells; Carbohydrate; Germinal Centre; Glycan; Immunomodulatory; Lymphoma; Siglec; Somatic Hypermutation

$983,026

Nano-Flow Liquid Chromatography Equipment for Mass Spectrometry

Co-investigatorNSERC2025Research Tools and Instruments

Principal investigators: Uhrig, Richard

Keywords: quantitative proteomics; post-translational modifications; time-course experimentation; large sample cohort analysis; agriculture; single cell proteomics; circadian biology; abiotic stress; biochemistry

$150,000

Early Life Determinant of T1D Susceptibility

Co-investigatorCIHR2023Project Grant

Principal investigators: Tsai, Sue Y

Keywords: Autoimmunity; Early Life Events; Humoral Immunity; Iga; Insulitis; Maternal Factors; Microbiota; Postnatal; Type 1 Diabetes

$1,048,050

Understanding CD33 as a Genetic Susceptibility Factor in Alzheimer's Disease

Co-investigatorCIHR2023Project Grant

Principal investigators: Macauley, Matthew S

Keywords: Alzheimer'S Disease; Amyloid; Cd33; Microglia; Neurodegeneration; Siglec; Splicing; Trem2

$1,097,775

Programmed Glycosylation Changes in Controlling the Germinal Center

Co-investigatorCIHR2022Project Grant

Principal investigators: Macauley, Matthew S

Keywords: Antibody; Antibody Affinity Maturation; B Cell; Carbohydrate; Cell-Cell Interactions; Germinal Centre,; Glycan; Humoral Immunity,; Somatic Hypermutation; T Cell

$860,626

COVID-19 Variant Supplement - Therapeutic approaches to SARS-CoV-2 and other pathogenic coronaviruses

Co-investigatorCIHR2021Operating Grant: SARS-CoV-2 variants supplement stream 1

Principal investigators: Hobman, Tom C

Keywords: Antivirals; Coronavirus; Emerging Viruses; Sars; Vaccines

$49,533

Advancing the therapeutic opportunity for TLR4 in reducing cisplatin-induced ototoxicity

Co-investigatorCIHR2021Project Grant

Principal investigators: Bhavsar, Amit P

Keywords: Chemotherapy-Related Toxicity; Childhood Cancer Treatment; Hearing Loss; Innate Immune Receptor; Innovative Pharmacological Agents; Otoprotectant Development; Small Molecule Screening

$956,250

Rational design and standardization of serology diagnostics using immunoaffinity-targeted proteomics assays

Co-investigatorCIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Diagnostics

Principal investigators: Drabovich, Andrei P

Keywords: Antibody Isotypes; Elisa; Neutralizing Antibodies; Quantitative Mass Spectrometry; Serology Diagnostics; Standardization; Targeted Proteomics

Therapeutic approaches to SARS-CoV-2 and other pathogenic coronaviruses

Co-investigatorCIHR2020Operating Grant: COVID-19 - Therapeutics

Principal investigators: Hobman, Tom C

Keywords: Antivirals; Coronavirus; Emerging Viruses; Sars; Vaccines

$998,300

Alphavirus-host interactions: Toward novel antiviral therapies.

Co-investigatorCIHR2018Project Grant

Principal investigators: Hobman, Tom C

Keywords: Antiviral; Arthritis; Chikungunya Virus; Interactome; Mayaro Virus; Protease; Transcriptomics

$1,137,940

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Olivier Julien

Research

Latest papers

Latest funding

Structure and Function of a Multi-Megadalton Virus-Like Proteolytic Dodecahedron.

Caspase-mediated cleavage events hidden by secondary proteolysis during apoptosis.

A metabolite extracted from Escherichia coli suppresses tau aggregation.

Siglec-G on B cells restrains the germinal center response by controlling T cell help during positive selection.

Expression of progerin enhances disease-related endpoints in a tau seeding reporter cell system.

Brain and neural cell type proteomics reveal extracellular matrix proteins enriched in progressive multiple sclerosis.

Sacubitril suppresses experimental chronic heart allograft vasculopathy.

Rhomboid protease GlpG regulates type 1 pili quality control and virulence in pathogenic E. coli.

The vaccinia virus protein, C16, promotes the ubiquitylation and relocalization of the antiviral E3 ubiquitin-ligase, TRIM25.

Investigation of CD36 interactome provides insights into multimolecular complexes necessary for anti-angiogenic signalling.

Nano-Flow Liquid Chromatography Equipment for Mass Spectrometry

Frequent collaborators

Richard Schulz

David Westaway

Nicolas Touret

Richard Fahlman

Christopher Power

Sue-Ann Mok

Holger Wille

Antoine Dufour

Qiumin Tan

Eytan Wine

Justin Chun

Wael Elhenawy

Shima Shahbaz

Fabrizio Giuliani

Heather Armstrong

Mohan Babu

Marek Michalak

Harissios Vliagoftis

Shokrollah Elahi

Zamaneh Kassiri