Saeid Ghavami, University of Manitoba

Research

Read how they describe their research on their University of Manitoba profile.

Autophagy Bcl2 family proteins Cell phenotype Chemo-resistance Glioblastoma Lung cancer Mevalonate cascade Mitophagy Rhabdomyosarcoma

Latest papers

Autophagy-exosome crosstalk in neurodegeneration: Mechanisms and therapeutic opportunities.
Pharmacology & therapeutics · 2026
Micro- and Nanoplastics in the Human Brain: Mechanistic Plausibility, Translational Challenges, and Links to Neurological Disease Trends.
Molecular neurobiology · 2026
Special Issue "Invasion and Metastasis in Brain Cancer".
International journal of molecular sciences · 2026 · senior author

All 256 publications

Latest funding

The S100A8/A9-RAGE Axis in Airway Inflammation, Hyperresponsiveness, and Remodeling
CIHR · 2010 · Co-investigator
$747,468
The S100A8/A9-RAGE Axis in Airway Inflammation, Hyperresponsiveness, and Remodeling
CIHR · 2009 · Co-investigator
$113,912

All 2 grants and awards

From the 150 most recent of 256 publications.

01

Autophagy-exosome crosstalk in neurodegeneration: Mechanisms and therapeutic opportunities.

Sedighi S, Guan T, Michetti F, Cordani M, Barzegar Behrooz A, Sabouni F, Eshraghi M, Saleem A, Ghavami S, Aghanoori MR

Pharmacology & therapeutics20262 citationsOpen Access

DOI: 10.1016/j.pharmthera.2026.109025 PMID: 41833626

02

Micro- and Nanoplastics in the Human Brain: Mechanistic Plausibility, Translational Challenges, and Links to Neurological Disease Trends.

Ghiyamihoor F, Asemi Rad A, Hassanifar P, Kaur R, Patel JH, Kim I, Marzban A, Mehdizadeh M, Levin DB, Ghavami S, Toncheva A, Benali S, Dubois P, Balci F, Habibi HR, Manto M, Marzban H

Molecular neurobiology20261 citations

DOI: 10.1007/s12035-026-05895-9 PMID: 42059992

03

Special Issue "Invasion and Metastasis in Brain Cancer".

Glogowska A, Ghavami S

International journal of molecular sciences2026Senior authorOpen Access

DOI: 10.3390/ijms27031555 PMID: 41683974

04

Epigenetic regulation of autophagy in cancer: A double-edged sword in tumor progression and therapy resistance.

Barzegar Behrooz A, Cordani M, Ghavami S

International review of cell and molecular biology2026Senior author

DOI: 10.1016/bs.ircmb.2025.08.002 PMID: 41905789

05

Autophagy and cellular metabolism in civilization diseases.

Cordani M, Łos MJ, Ghavami S

European journal of pharmacology2026Senior author

DOI: 10.1016/j.ejphar.2026.178636 PMID: 41638624

06

Phytochemistry and pharmacology of Melaleuca alternifolia: Bridging aboriginal heritage with contemporary science.

Ebrahimi N, Shokouhi H, Omrani M, Tavakoli MM, Vojdani A, Carson C, Mehrbod P, Ghavami S

Biochimica et biophysica acta. General subjects2026Senior author

DOI: 10.1016/j.bbagen.2026.130917 PMID: 41679395

07

Circular RNAs and SIRT1 in post-transcriptional regulation and human disease.

Vakili O, Yousefi Z, Igder S, Yarahmadi S, Gheibi M, Taghizadeh M, Moshtaghian MS, Sartavi F, Yahyazadeh S, Shafiee SM, Ghavami S

Biochimica et biophysica acta. Molecular basis of disease2026Senior author

DOI: 10.1016/j.bbadis.2026.168451 PMID: 42700874

08

Pharmacological modulation of ATF6: exploiting a stress-integrative node to overcome drug resistance.

Mashhadi MH, Aghaei M, Ghavami S

Drug discovery today2026Senior author

DOI: 10.1016/j.drudis.2026.104734 PMID: 42425265

09

Harnessing hitchhikers: Outer membrane vesicles leading the way in advanced cancer therapeutics and diagnostic- A review.

Sharifzad F, Sharifzad A, Thumbikat P, Purnaghshband H, Ghamari A, Vaseghi G, Mahmoodzadeh A, Assefi M, Los MJ, Ghavami S

Cancer letters2026Senior author

DOI: 10.1016/j.canlet.2026.218370 PMID: 41763447

10

Suboptimal Responses to Anti-VEGF in Retinal Neurovascular Diseases: Linking Aging and Alternative Angioinflammatory Pathways.

Piroozmand S, Latifi-Navid H, Soheili ZS, Hosseinkhani S, Samiei S, Barzegar Behrooz A, Ahmadieh H, Leonardi A, Ghavami S, Sheibani N

Investigative ophthalmology & visual science2026

DOI: 10.1167/iovs.67.5.4 PMID: 42080790

The S100A8/A9-RAGE Axis in Airway Inflammation, Hyperresponsiveness, and Remodeling

Co-investigatorCIHR2010Operating Grant

Principal investigators: Halayko, Andrew J

Keywords: Airway Remodeling; Airway Smooth Muscle; Asthma; Mouse Models Of Asthma; Neutrophils; Rage

$747,468

The S100A8/A9-RAGE Axis in Airway Inflammation, Hyperresponsiveness, and Remodeling

Co-investigatorCIHR2009CIHR/Regional Partnership Program/Operating Grants

Principal investigators: Halayko, Andrew J

Keywords: Airway Remodeling; Airway Smooth Muscle; Asthma; Mouse Models Of Asthma; Neutrophils; Rage

$113,912

From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.

Frequent collaborators

Thomas Klonisch and Sabine Hombach-Klonisch: 118 shared papers
Thomas Klonisch and Aleksandra Glogowska: 35 shared papers
Thomas Klonisch and Saeid Ghavami: 28 shared papers
Thomas Klonisch and Andrew Halayko: 24 shared papers
Andrew Halayko and Saeid Ghavami: 20 shared papers
Sabine Hombach-Klonisch and Aleksandra Glogowska: 20 shared papers
Joseph Gordon and Adrian West: 17 shared papers
Ayesha Saleem and Joseph Gordon: 14 shared papers
Joseph Gordon and Saeid Ghavami: 12 shared papers
Grant Hatch and Joseph Gordon: 10 shared papers
Sabine Hombach-Klonisch and Saeid Ghavami: 10 shared papers
Hassan Marzban and Saeid Ghavami: 10 shared papers
Mohsen Akbari and Saeid Ghavami: 9 shared papers
Andrew Halayko and Ian Dixon: 9 shared papers
Grant Hatch and Thomas Klonisch: 8 shared papers
Kevin Coombs and Saeid Ghavami: 8 shared papers
Thomas Klonisch and Ian Dixon: 8 shared papers
Andrew Halayko and Amir Ravandi: 8 shared papers
Ian Dixon and Saeid Ghavami: 8 shared papers
Ayesha Saleem and Adrian West: 8 shared papers
Grant Hatch and Sabine Hombach-Klonisch: 7 shared papers
Grant Hatch and Saeid Ghavami: 6 shared papers
Thomas Klonisch and Jörg Stetefeld: 6 shared papers
Mohsen Akbari and Joseph Gordon: 6 shared papers
Aleksandra Glogowska and Saeid Ghavami: 6 shared papers
Grant Hatch and Adrian West: 5 shared papers
Grant Hatch and Amir Ravandi: 5 shared papers
Kevin Coombs and Andrew Halayko: 5 shared papers
Eftekhar Eftekharpour and Saeid Ghavami: 5 shared papers
Amir Ravandi and Saeid Ghavami: 5 shared papers
Grant Hatch and Mohsen Akbari: 4 shared papers
Grant Hatch and Ayesha Saleem: 4 shared papers
Kevin Coombs and Thomas Klonisch: 4 shared papers
Sabine Hombach-Klonisch and Jörg Stetefeld: 4 shared papers
Jörg Stetefeld and Saeid Ghavami: 4 shared papers
Saeid Ghavami and Sajjad Aftabi: 4 shared papers
Martin Post and Saeid Ghavami: 3 shared papers
Edward Fon and Calvin Yip: 3 shared papers
Edward Fon and Andrew Halayko: 3 shared papers
Grant Hatch and Eftekhar Eftekharpour: 3 shared papers
Mojgan Rastegar and Saeid Ghavami: 3 shared papers
Kevin Coombs and Eftekhar Eftekharpour: 3 shared papers
Jude Uzonna and Saeid Ghavami: 3 shared papers
Mohsen Akbari and Hassan Marzban: 3 shared papers
Prashen Chelikani and Saeid Ghavami: 3 shared papers
Benedict Albensi and Eftekhar Eftekharpour: 3 shared papers
Benedict Albensi and Saeid Ghavami: 3 shared papers
Ayesha Saleem and Saeid Ghavami: 3 shared papers
Joseph Gordon and Benjamin Lindsey: 3 shared papers
Martin Post and Ian Dixon: 2 shared papers
Edward Fon and Saeid Ghavami: 2 shared papers
Calvin Yip and Andrew Halayko: 2 shared papers
Calvin Yip and Saeid Ghavami: 2 shared papers
Grant Hatch and Hassan Marzban: 2 shared papers
Mojgan Rastegar and Hassan Marzban: 2 shared papers
Jude Uzonna and Andrew Halayko: 2 shared papers
Thomas Klonisch and Prashen Chelikani: 2 shared papers
Benjamin Lindsey and Saeid Ghavami: 2 shared papers
Adrian West and Saeid Ghavami: 2 shared papers
Martin Post and Edward Fon: 1 shared paper
Grant Hatch and Jude Uzonna: 1 shared paper
Mojgan Rastegar and Eftekhar Eftekharpour: 1 shared paper
Andrew Halayko and Prashen Chelikani: 1 shared paper
Benjamin Lindsey and Hassan Marzban: 1 shared paper

Department of Human Anatomy and Cell Science
Faculty of Health Science/Nursing
Centre for Biomedical Research
Department of Physiology & Pathophysiology
Chemistry
Department of Radiology
Dr. Gerald Niznick College of Dentistry
Other

Co-authors at University of Manitoba, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Thomas Klonisch

Department of Human Anatomy and Cell Science

28 shared papers, latest 2023

Andrew Halayko

Faculty

20 shared papers, latest 2021

Joseph Gordon

Faculty of Health Science/Nursing

12 shared papers, latest 2025

Hassan Marzban

Department of Human Anatomy and Cell Science

10 shared papers, latest 2026

Sabine Hombach-Klonisch

Faculty

10 shared papers, latest 2023

Mohsen Akbari

Centre for Biomedical Research

9 shared papers, latest 2021

Kevin Coombs

Faculty

8 shared papers, latest 2025

Ian Dixon

Faculty

8 shared papers, latest 2021

Aleksandra Glogowska

Department of Human Anatomy and Cell Science

6 shared papers, latest 2026

Grant Hatch

Faculty

6 shared papers, latest 2021

Amir Ravandi

Department of Physiology & Pathophysiology

5 shared papers, latest 2025

Eftekhar Eftekharpour

Faculty

5 shared papers, latest 2021

Sajjad Aftabi

Department of Radiology

4 shared papers, latest 2025

Jörg Stetefeld

Chemistry

4 shared papers, latest 2015

Spencer Gibson

Manitoba Institute of Cell Biology

4 shared papers, latest 2021

Ayesha Saleem

Dr. Gerald Niznick College of Dentistry

3 shared papers, latest 2026

Mojgan Rastegar

Faculty

3 shared papers, latest 2019

Benedict Albensi

Faculty

3 shared papers, latest 2025

Jude Uzonna

Faculty

3 shared papers, latest 2025

Martin Post

Department of Paediatrics

3 shared papers, latest 2021

Prashen Chelikani

Department of Oral Biology

3 shared papers, latest 2025

Sanjay Dhingra

Department of Medicine

2 shared papers, latest 2023

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Paper to mention

Subject: Prospective PhD student: Autophagy Dear Professor Ghavami, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Autophagy-exosome crosstalk in neurodegeneration: Mechanisms and therapeutic opportunities." (2026), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]