Faculty profile

Sam Saibil

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Assistant ProfessorDepartment of MedicineUniversity of Toronto

Sam Saibil

Assistant Professor

Department of Medicine

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
68 publications in the last five years, latest in 2026.
Senior (last) author on 10 recent papers, a sign of leading a research group.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

102

Publications

1,723

Citations

Collaborators

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Response to Immune Checkpoint Blockade Is Enhanced in the Presence of Hematopoietic TET2 Inactivation.
Cancer research · 2026
Autologous T-cell antigen coupler targeting HER2 (TAC01-HER2) in advanced or metastatic solid tumors
Annals of Oncology · 2026
CD28-driven ex vivo generation of stem-like memory CD8+ T cells bypassing CD3/TCR signaling.
Proceedings of the National Academy of Sciences of the United States of America · 2026

All 102 publications

102 publications.

Response to Immune Checkpoint Blockade Is Enhanced in the Presence of Hematopoietic TET2 Inactivation.

Rondeau V, Bansal S, Buttigieg MM, Zeng AGX, Chan DY, Chan-Seng-Yue M, Jin L, McLeod J, Kates M, Donato E, Stelmach P, Vlasschaert C, Yang Y, Gupta A, Genta S, Sanz-Garcia E, Shlush L, Ribeiro M, Butler MO, Abelson S, Minden MD, Saibil SD, Chan SM, Rauh MJ, Trumpp A, Dick JE, Vanner RJ

Cancer research20267 citations

DOI: 10.1158/0008-5472.can-24-3329 PMID: 41218172

Autologous T-cell antigen coupler targeting HER2 (TAC01-HER2) in advanced or metastatic solid tumors

Ecaterina E. Dumbrava, Daniel Olson, Mohamed Alaa Gouda, Mridula A. George, Samuel D. Saibil, Maria Apostolopoulou, M. C. Bishop, Miriam N. Gavriliuc, Amber M. Kennon, Jordan A. Weiss, Chris Ayers, Kara Moss, Christopher W. Helsen, Donna Rill, Andreas G. Bader, Deyaa Adib, Benjamin L. Schlechter

Annals of Oncology2026

DOI: 10.1016/j.annonc.2026.05.696 PMID: 42177028

CD28-driven ex vivo generation of stem-like memory CD8+ T cells bypassing CD3/TCR signaling.

Ihara F, Ohashi Y, Zheng EYF, Fukao S, Rodrigo R, Noamani B, Boukhaled GM, Wang BX, Han DH, Wei X, Burt BD, Saso K, Matsunaga Y, Ly D, Kagoya Y, Butler MO, Mak TW, Saibil SD, Hirano N

Proceedings of the National Academy of Sciences of the United States of America2026Open Access

DOI: 10.1073/pnas.2524626123 PMID: 42012954

Data from Response to Immune Checkpoint Blockade Is Enhanced in the Presence of Hematopoietic TET2 Inactivation

Vincent Rondeau, Suraj Bansal, Marco M. Buttigieg, Andy G.X. Zeng, Darryl Y. Chan, Michelle Chan Seng Yue, Jin Liqing, Jessica L. McLeod, Meghan Kates, Elisa Donato, Patrick Stelmach, Caitlyn Vlasschaert, Yitong Yang, Aarushi Gupta, Sofia Genta, Enrique Sanz Garcia, Liran Shlush, Maurício Fernando Silva Almeida Ribeiro, Marcus Otho Butler, Sagi Abelson, Mark D. Minden, Samuel D. Saibil, Steven M. Chan, Michael J. Rauh, Andreas Trumpp, John Edgar Dick, Robert J. Vanner

2026Open Access

DOI: 10.1158/0008-5472.c.8311796

Impact of immune checkpoint inhibitors on pregnancy: current evidence and future directions

Iman Salehi, Christine Elser, Samuel D. Saibil, Cynthia Vivianne Maxwell

BMJ Oncology2026Open Access

DOI: 10.1136/bmjonc-2026-001134 PMID: 42553688

An Audit of Accessibility and Actionability of Molecular Profiling for Patients with Cancer of Unknown Primary at a Tertiary Care Centre

Khaled Abdulalem, Jonah Teich, Erika A. Martinez, Samuel D. Saibil

Clinics and Practice2026Senior authorOpen Access

DOI: 10.3390/clinpract16020039 PMID: 41744522

How we treat patients with metastatic uveal melanoma

Erick Figueiredo Saldanha, Maria Flávia Marques Ribeiro, Ian Hirsch, A. Spreafico, Samuel D. Saibil, Marcus O. Butler

ESMO Open202515 citationsOpen Access

DOI: 10.1016/j.esmoop.2025.104496 PMID: 40112696

LARP4-mediated hypertranslation drives T cell dysfunction in tumors

Yi Liu, Haochen Ni, Jie Li, Jing Yang, Ivann Sekielyk, Bryan E. Snow, Zihao Zhang, Feifan Zhang, Michael St. Paul, Jinyi Han, Meghan Kates, Shaofeng Liu, Yawei Zhang, Zurui Huang, Yin Xu, Samuel D. Saibil, Tak W. Mak, Dali Han, Meng Michelle Xu

Nature Immunology202510 citations

DOI: 10.1038/s41590-025-02232-5 PMID: 40696044

Prognostic and Predictive Value of ct DNA for Metastatic Uveal Melanoma: A Systematic Review and Meta‐Analysis

Mariana Macambira Noronha, Luís Felipe Leite, Luiz F. Costa de Almeida, Pedro Robson Costa Passos, Pedro Cotta Abrahão Reis, João Evangelista Ponte Conrado, Valbert Oliveira Costa Filho, Lucas Diniz da Conceição, Maurício Fernando Silva Almeida Ribeiro, Samuel D. Saibil, Erick Figueiredo Saldanha

Pigment Cell & Melanoma Research20257 citationsOpen Access

DOI: 10.1111/pcmr.70047 PMID: 40799039

Molecular Tumor Board-Guided Targeted Treatments for Biliary Tract Cancers in a Publicly Funded Healthcare System.

Beaudry FEG, Li Z, Borgida A, Zorigtbaatar A, Wang X, Hildebrand M, Hamza O, Jang GH, Bucur R, Dodd A, Wilson J, Auer RC, Saibil S, Tsang ES, Vogel A, O'Kane GM, Gallinger S, Knox JJ, Notta F, Sapisochin G, Grant RC

Current oncology (Toronto, Ont.)20255 citationsOpen Access

DOI: 10.3390/curroncol32020080 PMID: 39996880

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Sam Saibil

Research

Latest papers

Response to Immune Checkpoint Blockade Is Enhanced in the Presence of Hematopoietic TET2 Inactivation.

Autologous T-cell antigen coupler targeting HER2 (TAC01-HER2) in advanced or metastatic solid tumors

CD28-driven ex vivo generation of stem-like memory CD8+ T cells bypassing CD3/TCR signaling.

Data from Response to Immune Checkpoint Blockade Is Enhanced in the Presence of Hematopoietic TET2 Inactivation

Impact of immune checkpoint inhibitors on pregnancy: current evidence and future directions

An Audit of Accessibility and Actionability of Molecular Profiling for Patients with Cancer of Unknown Primary at a Tertiary Care Centre

How we treat patients with metastatic uveal melanoma

LARP4-mediated hypertranslation drives T cell dysfunction in tumors

Prognostic and Predictive Value of ct DNA for Metastatic Uveal Melanoma: A Systematic Review and Meta‐Analysis

Molecular Tumor Board-Guided Targeted Treatments for Biliary Tract Cancers in a Publicly Funded Healthcare System.

Frequent collaborators

Samuel Saibil

Pamela Ohashi

Anna Spreafico

Trevor Pugh

Russell Jones

Dominic Roy

April Rose

Lillian Siu

Philippe Bedard

Alexandra Easson

Naoto Hirano

Benjamin Haibe-Kains

Michael Zon

Sareh Keshavarzi

Adrian Sacher

Tak Mak

Lawson Eng

Ian King

John Kuruvilla

Tracy Stockley

Jim Woodgett

John Waldron

Ming Tsao

Wey Leong

Leslie Po

Edward Margolin

Rob Rottapel

Sagi Abelson