Faculty profile

Petronela Ancuta

ResearcherMicrobiologie et immunologieUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Petronela Ancuta

Researcher

Microbiologie et immunologie

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
13 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 16 research grants (16 CIHR), most recently in 2024.
Supervised 1 trainee who won CIHR awards, most recently in 2010.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Antiretroviral Therapy Hiv-1 Th17 Cells Hiv Cure Hiv Persistence Hiv Reservoirs Crispr Cas9 Rna Sequencing

Latest papers

Dietary intervention through bacterial-derived butyrate elicits anti-tumor activity and increases anti-PD-1 response.
Gut microbes · 2026
HCV-specific CD4+ T-cells are susceptible to HIV-1 and contribute to viral persistence during antiretroviral therapy.
EBioMedicine · 2026
Alterations in Circulating T-Cell Subsets with Gut-Homing/Residency Phenotypes Associated with HIV-1 Status and Subclinical Atherosclerosis.
Cells · 2025 · senior author

All 48 publications

Latest funding

Exploiting Innate Immune Sensing to Accelerate the Depletion of HIV Reservoirs
CIHR · 2025 · Co-investigator
$1,032,750
Identification of Aryl Hydrocarbon Receptor as a Novel Druggable Modulator of HIV-1 Latency
CIHR · 2024 · Nominated PI
$1,285,200
Aging with HIV: understanding heterogeneity to promote health for all
CIHR · 2024 · Co-investigator
$19,690

All 31 grants and awards

48 publications.

Dietary intervention through bacterial-derived butyrate elicits anti-tumor activity and increases anti-PD-1 response.

Benlaïfaoui M, Richard C, Hunter S, Méndez-Salazar EO, Kourtian S, Malo J, Prifti DK, Ponce M, Khalfi S, Belkaïd W, Messaoudene M, Boidot R, Truntzer C, Girhinghelli F, Lehoux-Duboix C, Ancuta P, Elkrief A, Marcil V, Routy B

Gut microbes2026

DOI: 10.1080/19490976.2026.2699457 PMID: 42454784

HCV-specific CD4+ T-cells are susceptible to HIV-1 and contribute to viral persistence during antiretroviral therapy.

Gobran ST, Ortiz AE, Khedr O, Dion J, Raymond Marchand L, Dias J, Cattin A, Bruneau J, Chomont N, Klein MB, Ancuta P, Shoukry NH

EBioMedicine2026

DOI: 10.1016/j.ebiom.2026.106365 PMID: 42398181

Alterations in Circulating T-Cell Subsets with Gut-Homing/Residency Phenotypes Associated with HIV-1 Status and Subclinical Atherosclerosis.

Moreira Gabriel E, Dias J, Filali-Mouhim A, Caballero RE, Wiche Salinas TR, Nayrac M, Chartrand-Lefebvre C, Routy JP, Durand M, El-Far M, Tremblay C, Ancuta P

Cells2025Senior author

DOI: 10.3390/cells14211732 PMID: 41227377

Altered memory CCR6+ Th17-polarised T-cell function and biology in people with HIV under successful antiretroviral therapy and HIV elite controllers.

Yero A, Goulet JP, Shi T, Costiniuk CT, Routy JP, Tremblay C, Mboumba Bouassa RS, Alexandrova Y, Pagliuzza A, Chomont N, Ancuta P, Jenabian MA

EBioMedicine2024

DOI: 10.1016/j.ebiom.2024.105274 PMID: 39178742

Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms.

Dias J, Cattin A, Bendoumou M, Dutilleul A, Lodge R, Goulet JP, Fert A, Raymond Marchand L, Wiche Salinas TR, Ngassaki Yoka CD, Gabriel EM, Caballero RE, Routy JP, Cohen ÉA, Van Lint C, Ancuta P

Cell reports2024Senior author

DOI: 10.1016/j.celrep.2024.114414 PMID: 38943643

Genetic haute couture to block HIV-1 at front doors.

Ancuta P

Cell stem cell2024First author

DOI: 10.1016/j.stem.2024.03.009 PMID: 38579679

Alterations in Th17 Cells and Non-Classical Monocytes as a Signature of Subclinical Coronary Artery Atherosclerosis during ART-Treated HIV-1 Infection.

Wiche Salinas TR, Zhang Y, Gosselin A, Rosario NF, El-Far M, Filali-Mouhim A, Routy JP, Chartrand-Lefebvre C, Landay AL, Durand M, Tremblay CL, Ancuta P, Canadian HIV and Aging Cohort Study (CHACS)

Cells2024Senior author

DOI: 10.3390/cells13020157 PMID: 38247848

Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART.

Dufour C, Ruiz MJ, Pagliuzza A, Richard C, Shahid A, Fromentin R, Ponte R, Cattin A, Wiche Salinas TR, Salahuddin S, Sandstrom T, Schinkel SB, Costiniuk CT, Jenabian MA, Ancuta P, Routy JP, Cohen ÉA, Brumme ZL, Power C, Angel JB, Chomont N

Cell reports2023

DOI: 10.1016/j.celrep.2023.113053 PMID: 37676762

Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques.

Clain JA, Rabezanahary H, Racine G, Boutrais S, Soundaramourty C, Joly Beauparlant C, Jenabian MA, Droit A, Ancuta P, Zghidi-Abouzid O, Estaquier J

JCI insight2023

DOI: 10.1172/jci.insight.167856 PMID: 37485876

Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4+ T cells.

Chatterjee D, Zhang Y, Ngassaki-Yoka CD, Dutilleul A, Khalfi S, Hernalsteens O, Wiche Salinas TR, Dias J, Chen H, Smail Y, Goulet JP, Bell B, Routy JP, Van Lint C, Ancuta P

Cell reports2023Senior author

DOI: 10.1016/j.celrep.2023.112634 PMID: 37310858

Exploiting Innate Immune Sensing to Accelerate the Depletion of HIV Reservoirs

Co-investigatorCIHR2025Project Grant

Principal investigators: Chomont, Nicolas

Keywords: Bone Marrow; Gut; Hiv Reservoir; Innate Immune Sensing; Latency; Lymph Node; Mda5; Rig-I; Tissues

$1,032,750

Identification of Aryl Hydrocarbon Receptor as a Novel Druggable Modulator of HIV-1 Latency

Nominated PICIHR2024Project Grant

Principal investigators: Ancuta, Petronela

Keywords: Antiretroviral Therapy; Aryl Hydrocarbon Receptor (Ahr); Confocal Microscopy/Imagestream; Crispr Cas9, Sirna; Flow Cytometry Analysis And Sorting; Hiv-1 Viral Reservoirs; Humanized Mice For Hiv Infection; Latency Reversing Agents; Pcr/Rt-Pcr, Western Blotting; Rna Sequencing, Massspec, Chip-Seq, Cut&Run, Atac-Seq

$1,285,200

Aging with HIV: understanding heterogeneity to promote health for all

Co-investigatorCIHR2024T. Gr.: Embracing Diversity -HIV/AIDS/STBBI-Co-infections and Co-morbidities-LOI

Principal investigators: Durand, Madeleine; Monteith, Kenneth M; Chartrand-Lefebvre, Carl; Murzin, Kate

Keywords: Aging; Comorbidity; Gender; Hiv; Inflammation; People Who Use Drugs

$19,690

Canadian HIV Cure Enterprise 3.0: Targeting tissue HIV reservoirs

Principal investigatorCIHR2024TG: Biomedical Res. for HIV/AIDS/STBBI-Next-Gen.Therapeutic Interv.-Large Team

Principal investigators: Chomont, Nicolas; Margolese, Shari L; Ancuta, Petronela; Angel, Jonathan B; Cohen, Eric A; Costiniuk, Cecilia T; Murooka, Thomas T

Keywords: Cd4 T Cells; Hiv Cure; Hiv Immunity; Hiv Persistence; Hiv Reservoir; Human Studies; Humanized Mouse Models; Myeloid Cells; Therapeutic Interventions; Tissue

$3,750,000

Metformin and Broadly Neutralizing Antibodies to Accelerate HIV-1 Reservoir Decay During ART

Nominated PICIHR2024Ca. Gr.: Biomedical Res. for HIV/AIDS/STBBI -Next-gen. therapeutic interventions

Principal investigators: Ancuta, Petronela

Keywords: Ampk, Mtor, Creb, Rorc2, Ahr, Pparg; Antibody-Dependent Cellular Cytotoxicity (Adcc) Assay; Antiretroviral Therapy; Broadly Neutralizing Antibodies (Bnabs); Cd4+ T Lymphocytes, Nk Cells; Hiv-1; Humanized Mice Nsg-Hil15; Metformin; Rna-Seq, Chip-Seq, Atac-Seq, Pcr, Rt-Pcr, Voa, Tilda; Viral Reservoirs

$200,000

Identification of Aryl Hydrocarbon Receptor as a Novel Druggable Modulator of HIV-1 Latency

Nominated PICIHR2023Project Grant - Priority Announcement: Infection and Immunity

Principal investigators: Ancuta, Petronela

Keywords: Antiretroviral Therapy; Confocal Microscopy/Imagestream; Crispr Cas9; Flow Cytometry Analysis And Sorting; Hiv-1; Humanized Mice For Hiv Infection; Latency Reversing Agents; Pcr/Rt-Pcr; Rna Sequencing; Viral Reservoirs

$100,000

Finding the Perfect Time to Hunt for HIV: A Tale of 36 Hours at the CHUM

Nominated PICIHR2023CIHR Café Scientifique Program - Institute of Infection and Immunity

Principal investigators: Ancuta, Petronela; Rosenes, Ron

Keywords: Antiretroviral Therapy; Circadian Clock; Community Consultants; Hiv Cure Strategies; Hiv Reservoirs; Immunological Measurements; Knowledge Users; People Living With Hiv; Residual Hiv Transcription; Virological Measurements

$6,000

The Th17 Master Regulator RORC2 as a New Target for HIV Immune Therapy and Cure Strategy

Nominated PICIHR2021Project Grant

Principal investigators: Ancuta, Petronela

Keywords: Antiretroviral Therapy; Chromatin Ip; Confocal Microscopy/Image Stream; Crispr Cas9; Flow Cytometry Sorting; Hiv-1; Humanized Mice; Rna Sequencing; Rorc2; Th17 Cells

$887,400

The Th17 Master Regulator RORC2 as a New Target for HIV Immune Therapy and Cure Strategy

Nominated PICIHR2020Project Grant - Priority Announcement: HIV/AIDS and STBBI

Principal investigators: Ancuta, Petronela

Keywords: Confocal Microscopy; Crispr Cas9; Hiv Transcription; Hiv-1; Human Th17 Cells; Humanized Mice; Image Stream; Rna Sequencing; Rorc2 Reverse Agonists; Viral Reservoir Reactivation And Purging

$100,000

Immunosuppressive pathways and HIV reservoirs in tissues

Co-investigatorCIHR2019Project Grant

Principal investigators: Routy, Jean-Pierre

Keywords: Checkpoint; Functional Cure; Gut; Hiv Reservoirs; Immune Exhaustion; Immunosuppression; Inflammation; Lymph Nodes; Myeloid Cells

$780,300

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Petronela Ancuta

Research

Latest papers

Latest funding

Dietary intervention through bacterial-derived butyrate elicits anti-tumor activity and increases anti-PD-1 response.

HCV-specific CD4+ T-cells are susceptible to HIV-1 and contribute to viral persistence during antiretroviral therapy.

Alterations in Circulating T-Cell Subsets with Gut-Homing/Residency Phenotypes Associated with HIV-1 Status and Subclinical Atherosclerosis.

Altered memory CCR6+ Th17-polarised T-cell function and biology in people with HIV under successful antiretroviral therapy and HIV elite controllers.

Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms.

Genetic haute couture to block HIV-1 at front doors.

Alterations in Th17 Cells and Non-Classical Monocytes as a Signature of Subclinical Coronary Artery Atherosclerosis during ART-Treated HIV-1 Infection.

Near full-length HIV sequencing in multiple tissues collected postmortem reveals shared clonal expansions across distinct reservoirs during ART.

Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques.

Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4+ T&#xa0;cells.

Frequent collaborators

Jean-Pierre Routy

Jean-Pierre Routy

Nicolas Chomont

Nicolas Chomont

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Madeleine Durand

Madeleine Durand

Carl Chartrand-Lefebvre

Nicole Bernard

Nicole Bernard

Cecilia Costiniuk

Nathalie Grandvaux

Erwin Schurr

Cecilia Costiniuk

Sharon Walmsley

Christopher Power

Arielle Elkrief

Arnaud Droit

Hugo Soudeyns

Reina Bendayan

Robert Reinhard

Paul Macpherson

Michal Abrahamowicz

Mario Ostrowski

Guy Boivin

Christos Tsoukas

Cécile Tremblay

Christos Tsoukas

George Thanassoulis

Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4+ T cells.