Faculty profile

Nicolas Chomont

ResearcherMicrobiologie et immunologieUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Nicolas Chomont

Researcher

Microbiologie et immunologie

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
35 publications in the last five years, latest in 2026.
Senior (last) author on 7 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (7 CIHR), most recently in 2025.
Supervised 2 trainees who won CIHR awards, most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

109

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Hiv Reservoir Lymph Node Hiv Cure Bone Marrow Latency Tissues Hiv Persistence Human Studies

Latest papers

Phenotypic analysis of productively SIV-infected cells in blood and lymphoid tissues of rhesus macaques.
Cell reports · 2026 · senior author
Gaining biological insights through supervised data visualization.
Nature computational science · 2026
Dynamics of HIV reservoirs following repeated anti-SARS-CoV-2 vaccination.
Frontiers in immunology · 2026

All 109 publications

Latest funding

Exploiting Innate Immune Sensing to Accelerate the Depletion of HIV Reservoirs
CIHR · 2025 · Nominated PI
$1,032,750
Building Capacity in Innovative Adaptive Trial Designs for HIV and STBBI Research: The CTN-Québec Training Platform
CIHR · 2025 · Co-investigator
$800,000
Investigating the formation of the latent HIV reservoir during acute infection
CIHR · 2024 · Supervisor
$140,000

All 19 grants and awards

109 publications.

Phenotypic analysis of productively SIV-infected cells in blood and lymphoid tissues of rhesus macaques.

Trifone C, Pagliuzza A, Ding S, Nekorchuk M, Busman-Sahay K, Nayrac M, Finzi A, Kaufmann DE, Estes JD, Fromentin R, Chomont N

Cell reports2026Senior author

DOI: 10.1016/j.celrep.2026.117826 PMID: 42611705

Gaining biological insights through supervised data visualization.

Rhodes JS, Aumon A, Morin S, Girard M, Larochelle C, Brunet-Ratnasingham E, Pagliuzza A, Marchitto L, Zhang W, Cutler A, Grand'Maison F, Zhou A, Finzi A, Chomont N, Kaufmann DE, Zandee S, Prat A, Wolf G, Moon KR

Nature computational science2026

DOI: 10.1038/s43588-026-00999-7 PMID: 42380342

Dynamics of HIV reservoirs following repeated anti-SARS-CoV-2 vaccination.

Lu J, Ahmad A, Chomont N, Costiniuk CT

Frontiers in immunology2026

DOI: 10.3389/fimmu.2026.1829485 PMID: 42292490

Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy.

Talla A, Azevedo JLLC, Latif MB, Enriquez AB, Sanchez GP, Pelletier AN, Bal SK, Kumari S, Schuch V, Ghneim K, Rhodes A, Maldarelli F, Yarchoan R, Lurain K, Ramaswami R, Sharon E, Hess BW, D'Amico L, Martinez-Picado J, Chomont N, Lewin SR, Deeks SG, Fling SP, Cheever MA, Uldrick TS, Sharma AA, Sekaly RP

Nature medicine2026

DOI: 10.1038/s41591-025-04139-y PMID: 41680482

The CanCURE Survey: Gender-Based Differences in HIV Cure Research Priorities.

Lu J, Vulesevic B, Margolese S, Masching R, Tharao W, Cardinal C, Hedrich T, Mallais C, Dubé K, Cohen E, Chomont N, Costiniuk CT

Journal of personalized medicine2025

DOI: 10.3390/jpm15120623 PMID: 41440986

No evidence of direct activation of human neutrophil responses by multivalent prefusion trimeric SARS-CoV-2 Spike protein ex vivo.

Fortin A, Huot S, Caron E, Laflamme C, Pagliuzza A, Chomont N, Gilbert C, Zhang B, Kwong PD, Pouliot M, Grandvaux N

PloS one2025

DOI: 10.1371/journal.pone.0332261 PMID: 41160626

No Evidence of Direct Activation of Human Neutrophil Responses by Multivalent Prefusion Trimeric SARS-CoV-2 Spike Protein ex vivo.

Fortin A, Huot S, Caron E, Laflamme C, Pagliuzza A, Chomont N, Gilbert C, Zhang B, Kwong PD, Pouliot M, Grandvaux N

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2025.05.08.652856 PMID: 41031024

Activation of CXCR3+ Tfh cells and B cells in lymph nodes during acute HIV-1 infection correlates with HIV-specific antibody development.

Mitchell JL, Buranapraditkun S, Gantner P, Takata H, Dietze K, N'guessan KF, Pollara J, Nohara J, Muir R, Kroon E, Pinyakorn S, Tulmethakaan N, Manasnayakorn S, Chottanapund S, Thantiworasit P, Prueksakaew P, Ratnaratorn N, Puttamaswin S, Nuntapinit B, Fox L, Haddad EK, Paquin-Proulx D, Phanuphak P, Sacdalan CP, Phanuphak N, Ananworanich J, Hsu D, Vasan S, Ferrari G, Chomont N, Trautmann L, RV254 and RV304 Study Groups

Journal of virology2025

DOI: 10.1128/jvi.01532-24 PMID: 39932316

Altered memory CCR6+ Th17-polarised T-cell function and biology in people with HIV under successful antiretroviral therapy and HIV elite controllers.

Yero A, Goulet JP, Shi T, Costiniuk CT, Routy JP, Tremblay C, Mboumba Bouassa RS, Alexandrova Y, Pagliuzza A, Chomont N, Ancuta P, Jenabian MA

EBioMedicine2024

DOI: 10.1016/j.ebiom.2024.105274 PMID: 39178742

Similar Viral and Immune Characteristics of Kaposi Sarcoma in ART-treated People Living With HIV and Older Patients With Classic Kaposi Sarcoma.

Royston L, Jary A, Berini CA, Mabanga T, Lin J, Pagliuzza A, Chomont N, Litvinov IV, Calmy A, Leducq V, Calvez V, Marcelin AG, Isnard S, Routy JP

Open forum infectious diseases2024

DOI: 10.1093/ofid/ofae404 PMID: 39100526

Exploiting Innate Immune Sensing to Accelerate the Depletion of HIV Reservoirs

Nominated PICIHR2025Project Grant

Principal investigators: Chomont, Nicolas

Keywords: Bone Marrow; Gut; Hiv Reservoir; Innate Immune Sensing; Latency; Lymph Node; Mda5; Rig-I; Tissues

$1,032,750

Building Capacity in Innovative Adaptive Trial Designs for HIV and STBBI Research: The CTN-Québec Training Platform

Co-investigatorCIHR2025HIV/AIDS & STBBI Clinical Trials Research Network - Phase 2

Principal investigators: Durand, Madeleine; Beaudry, Sylvain; Fontaine, Guillaume; Gilbert, Caroline; Golchi, Shirin; Greenstreet, Peter J; Hedrich, Tanguy; Lebouché, Bertrand; Lessard, David; Vicente, Sergio

Keywords: Adaptive Trials; Hiv; Implementation Science; Stbbi; Training

$800,000

Investigating the formation of the latent HIV reservoir during acute infection

SupervisorCIHR2024CIHR Fellowship

Principal investigators: Rosas Umbert, Miriam

Keywords: Acute Infection; Global Health; Hiv Infection; Hiv Latent Reservoir; Intact Provirus; Viral Replication; Virus Reconstruction

$140,000

Aging with HIV: understanding heterogeneity to promote health for all

Co-investigatorCIHR2024T. Gr.: Embracing Diversity -HIV/AIDS/STBBI-Co-infections and Co-morbidities-LOI

Principal investigators: Durand, Madeleine; Monteith, Kenneth M; Chartrand-Lefebvre, Carl; Murzin, Kate

Keywords: Aging; Comorbidity; Gender; Hiv; Inflammation; People Who Use Drugs

$19,690

The RESTART Trial: Reducing Systemic inflammation for people on AntiRetroviral Therapy.

Co-investigatorCIHR2024TG: Interv. Trial in Inflam. Chronic Cond. -CIHR HIV/AIDS/STBBI Res. Initiative

Principal investigators: Durand, Madeleine; Margolese, Shari L; Finzi, Andrés

Keywords: Aging; Cardiovascular; Comorbidity; Hiv; Inflammation

$1,999,997

Canadian HIV Cure Enterprise 3.0: Targeting tissue HIV reservoirs

Nominated PICIHR2024TG: Biomedical Res. for HIV/AIDS/STBBI-Next-Gen.Therapeutic Interv.-Large Team

Principal investigators: Chomont, Nicolas; Margolese, Shari L; Ancuta, Petronela; Angel, Jonathan B; Cohen, Eric A; Costiniuk, Cecilia T; Murooka, Thomas T

Keywords: Cd4 T Cells; Hiv Cure; Hiv Immunity; Hiv Persistence; Hiv Reservoir; Human Studies; Humanized Mouse Models; Myeloid Cells; Therapeutic Interventions; Tissue

$3,750,000

Closing the Comorbidity Gap for People Living with HIV : a Randomized Controlled Trial of Fostemsavir to Reduce Inflammaging

Co-investigatorCIHR2023TG:Interv. Trial in Inflam. Chronic Cond. - CIHR HIV/AIDS & STBBI Res. Init. LOI

Principal investigators: Durand, Madeleine; Margolese, Shari L; Finzi, Andrés; Monteith, Kenneth M

Keywords: Aging; Cardiovascular; Comorbidity; Hiv; Inflammation

$20,000

Inflammatory phenotype, senescence, and viscoelasticity imaging of macrophages in HIV

Co-investigatorCIHR2023Project Grant

Principal investigators: Cloutier, Guy

Keywords: Acoustic Shear Wave Analysis; Cell Elasticity; Cell Viscosity; Early Atherosclerosis; Imaging Of Cell Biomechanics; Immune System Senescence; Macrophage Engulfing; Macrophages; People Living With Hiv; Premature Aging

$726,750

COVIH study: COVID-19 burden in HIV infected individuals.

Co-investigatorCIHR2021Op. Gr.:Emerging COVID-19 Res. Gaps & Priorities - HIV and SARS-CoV-2

Principal investigators: Tremblay, Cécile L; Monteith, Kenneth M; Durand, Madeleine

Keywords: Antibodies; Clinical Course; Covid-19; Epidemiology; Hiv; Immune Responses; Immunocompromised; Sars-Cov-2; Vaccine

$497,000

Immunovirological determinants of breakthrough COVID-19 disease in vaccinated or previously infected individuals

Co-investigatorCIHR2021Project Grant

Principal investigators: Kaufmann, Daniel E; Finzi, Andrés

Keywords: Covid-19; Host Determinants Of Disease; Immune Predictors Of Disease Risk; Personalized Medicine; Protective Antiviral Immunity; Sars-Cov-2; Sars-Cov-2 Reinfection; Sars-Cov-2 Vaccines; Sars-Cov-2 Variants; Systems Biology

$956,250

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Nicolas Chomont

Research

Latest papers

Latest funding

Phenotypic analysis of productively SIV-infected cells in blood and lymphoid tissues of rhesus macaques.

Gaining biological insights through supervised data visualization.

Dynamics of HIV reservoirs following repeated anti-SARS-CoV-2 vaccination.

Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy.

The CanCURE Survey: Gender-Based Differences in HIV Cure Research Priorities.

No evidence of direct activation of human neutrophil responses by multivalent prefusion trimeric SARS-CoV-2 Spike protein ex vivo.

No Evidence of Direct Activation of Human Neutrophil Responses by Multivalent Prefusion Trimeric SARS-CoV-2 Spike Protein ex vivo.

Activation of CXCR3+ Tfh cells and B cells in lymph nodes during acute HIV-1 infection correlates with HIV-specific antibody development.

Altered memory CCR6+ Th17-polarised T-cell function and biology in people with HIV under successful antiretroviral therapy and HIV elite controllers.

Similar Viral and Immune Characteristics of Kaposi Sarcoma in ART-treated People Living With HIV and Older Patients With Classic Kaposi Sarcoma.

Frequent collaborators

Nicolas Chomont

Jean-Pierre Routy

Jean-Pierre Routy

Petronela Ancuta

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Madeleine Durand

Madeleine Durand

Alexandre Prat

Carl Chartrand-Lefebvre

Bertrand Routy

Catherine Larochelle

Christopher Power

Talat Bessissow

Caroline Gilbert

Shari Margolese

David Lessard

Marc Pouliot

Wangari Tharao

Marina Klein

Wangari Tharao

Mario Ostrowski

Nathalie Grandvaux

Erwin Schurr

Nathalie Arbour

Ron Rosenes

Nadine Kronfli

Nicole Bernard

Sharon Walmsley

Cecilia Costiniuk

Sirui Zhou

Réjean Thomas

Sylvie Lesage

Renee Masching

Eric Cohen

Jérôme Estaquier

Reina Bendayan

Marina Klein

Renee Masching