Faculty profile

Nicolas Chomont

ResearcherMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.

Nicolas Chomont

Researcher

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
35 publications in the last five years, latest in 2026.
Senior (last) author on 7 recent papers, a sign of leading a research group.
Principal investigator on 1 research grant (1 CIHR), most recently in 2023.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

110

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

B Cells Clinical Research Fundamental Research Immune Memory Immunology Innate Cells Symposium T Cells

Latest papers

Phenotypic analysis of productively SIV-infected cells in blood and lymphoid tissues of rhesus macaques.
Cell reports · 2026 · senior author
Gaining biological insights through supervised data visualization.
Nature computational science · 2026
Dynamics of HIV reservoirs following repeated anti-SARS-CoV-2 vaccination.
Frontiers in immunology · 2026

All 110 publications

Latest funding

Curing HIV-1 reservoir cells by targeted delivery of CRISPR
CIHR · 2024 · Co-investigator
$200,000
ACBP as a target for immunometabolic reprogramming in people living with HIV
CIHR · 2024 · Co-investigator
$738,224
CIHR Pan-Canadian Network for HIV/AIDS and Sexually Transmitted and Blood Borne Infections (STBBI) Clinical Trials Research (CTN)
CIHR · 2024 · Co-investigator
$25,000,000

All 9 grants and awards

110 publications.

Phenotypic analysis of productively SIV-infected cells in blood and lymphoid tissues of rhesus macaques.

Trifone C, Pagliuzza A, Ding S, Nekorchuk M, Busman-Sahay K, Nayrac M, Finzi A, Kaufmann DE, Estes JD, Fromentin R, Chomont N

Cell reports2026Senior author

DOI: 10.1016/j.celrep.2026.117826 PMID: 42611705

Gaining biological insights through supervised data visualization.

Rhodes JS, Aumon A, Morin S, Girard M, Larochelle C, Brunet-Ratnasingham E, Pagliuzza A, Marchitto L, Zhang W, Cutler A, Grand'Maison F, Zhou A, Finzi A, Chomont N, Kaufmann DE, Zandee S, Prat A, Wolf G, Moon KR

Nature computational science2026

DOI: 10.1038/s43588-026-00999-7 PMID: 42380342

Dynamics of HIV reservoirs following repeated anti-SARS-CoV-2 vaccination.

Lu J, Ahmad A, Chomont N, Costiniuk CT

Frontiers in immunology2026

DOI: 10.3389/fimmu.2026.1829485 PMID: 42292490

Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy.

Talla A, Azevedo JLLC, Latif MB, Enriquez AB, Sanchez GP, Pelletier AN, Bal SK, Kumari S, Schuch V, Ghneim K, Rhodes A, Maldarelli F, Yarchoan R, Lurain K, Ramaswami R, Sharon E, Hess BW, D'Amico L, Martinez-Picado J, Chomont N, Lewin SR, Deeks SG, Fling SP, Cheever MA, Uldrick TS, Sharma AA, Sekaly RP

Nature medicine2026

DOI: 10.1038/s41591-025-04139-y PMID: 41680482

The CanCURE Survey: Gender-Based Differences in HIV Cure Research Priorities.

Lu J, Vulesevic B, Margolese S, Masching R, Tharao W, Cardinal C, Hedrich T, Mallais C, Dubé K, Cohen E, Chomont N, Costiniuk CT

Journal of personalized medicine2025

DOI: 10.3390/jpm15120623 PMID: 41440986

No evidence of direct activation of human neutrophil responses by multivalent prefusion trimeric SARS-CoV-2 Spike protein ex vivo.

Fortin A, Huot S, Caron E, Laflamme C, Pagliuzza A, Chomont N, Gilbert C, Zhang B, Kwong PD, Pouliot M, Grandvaux N

PloS one2025

DOI: 10.1371/journal.pone.0332261 PMID: 41160626

No Evidence of Direct Activation of Human Neutrophil Responses by Multivalent Prefusion Trimeric SARS-CoV-2 Spike Protein ex vivo.

Fortin A, Huot S, Caron E, Laflamme C, Pagliuzza A, Chomont N, Gilbert C, Zhang B, Kwong PD, Pouliot M, Grandvaux N

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2025.05.08.652856 PMID: 41031024

Activation of CXCR3+ Tfh cells and B cells in lymph nodes during acute HIV-1 infection correlates with HIV-specific antibody development.

Mitchell JL, Buranapraditkun S, Gantner P, Takata H, Dietze K, N'guessan KF, Pollara J, Nohara J, Muir R, Kroon E, Pinyakorn S, Tulmethakaan N, Manasnayakorn S, Chottanapund S, Thantiworasit P, Prueksakaew P, Ratnaratorn N, Puttamaswin S, Nuntapinit B, Fox L, Haddad EK, Paquin-Proulx D, Phanuphak P, Sacdalan CP, Phanuphak N, Ananworanich J, Hsu D, Vasan S, Ferrari G, Chomont N, Trautmann L, RV254 and RV304 Study Groups

Journal of virology2025

DOI: 10.1128/jvi.01532-24 PMID: 39932316

Altered memory CCR6+ Th17-polarised T-cell function and biology in people with HIV under successful antiretroviral therapy and HIV elite controllers.

Yero A, Goulet JP, Shi T, Costiniuk CT, Routy JP, Tremblay C, Mboumba Bouassa RS, Alexandrova Y, Pagliuzza A, Chomont N, Ancuta P, Jenabian MA

EBioMedicine2024

DOI: 10.1016/j.ebiom.2024.105274 PMID: 39178742

Similar Viral and Immune Characteristics of Kaposi Sarcoma in ART-treated People Living With HIV and Older Patients With Classic Kaposi Sarcoma.

Royston L, Jary A, Berini CA, Mabanga T, Lin J, Pagliuzza A, Chomont N, Litvinov IV, Calmy A, Leducq V, Calvez V, Marcelin AG, Isnard S, Routy JP

Open forum infectious diseases2024

DOI: 10.1093/ofid/ofae404 PMID: 39100526

Curing HIV-1 reservoir cells by targeted delivery of CRISPR

Co-investigatorCIHR2024Ca. Gr.: Biomedical Res. for HIV/AIDS/STBBI -Next-gen. therapeutic interventions

Principal investigators: Liang, Chen

Keywords: Crispr Gene Editing; Hiv/Aids; Lnps; Reservoirs; Targeted Delivery

$200,000

ACBP as a target for immunometabolic reprogramming in people living with HIV

Co-investigatorCIHR2024Project Grant

Principal investigators: Routy, Jean-Pierre

Keywords: Acyl Coa Binding Protein; Autophagy; Cd4 T-Cells; Cd8 T-Cells; Hiv; Immune Response; Immunometabolic Reprogramming; Inflammation; Metabolism; Oxidative Phosphorylation

$738,224

CIHR Pan-Canadian Network for HIV/AIDS and Sexually Transmitted and Blood Borne Infections (STBBI) Clinical Trials Research (CTN)

Co-investigatorCIHR2024HIV/AIDS & STBBI Clinical Trials Research Network - Phase 1

Principal investigators: Klein, Marina B; Habanyama, Muluba; Mandarino, Enrico; Martin, Carrie; Angel, Jonathan B; Anis, Aslam H; Brophy, Jason C; Burchell, Ann N; Coffin, Carla S; Costiniuk, Cecilia T; Daley, Peter; Durand, Madeleine; Fontaine, Guillaume; Golchi, Shirin; Grennan, Jonathan (Troy); Hart, Trevor A; Hull, Mark W; Keynan, Yoav; King, Elizabeth M; Kronfli, Nadine; Law, John Lok Man; Lebouché, Bertrand; Logie, Carmen; Mbuagbaw, Lawrence C; McGuinty, Michaeline; Murray, Melanie C; Shaw, Souradet Y; Smyth, Daniel J; Spence, Cara J; Tan, Darrell H; Walmsley, Sharon L; Wong, Alexander C; Worthington, Catherine A; Zhabokritsky, Alice

Keywords: Clinical Trials; Community Engaged; Cure; Hepatitis B And C; Hiv/Aids; Network; Prevention; Sexually Transmitted And Blood Borne Infections; Syphilis; Treatment

$25,000,000

Montreal Immunology Meetings Symposium: Immunological Memory of Innate and Adaptive Immune Cells

Principal investigatorCIHR2023Planning and Dissemination Grant - Institute Community Support

Principal investigators: Melichar, Heather; Chomont, Nicolas; Heinonen, Krista M; Thanabalasuriar, Ajitha

Keywords: B Cells; Clinical Research; Fundamental Research; Immune Memory; Immunology; Innate Cells; Symposium; T Cells; Trained Immunity

$10,000

Reversing CMV-induced gut damage to reduce inflammation and improve response to vaccine in people living with HIV

Co-investigatorCIHR2021Project Grant

Principal investigators: Routy, Jean-Pierre

Keywords: Cytomegalovirus; Gut; Hiv; Inflammation; Letermovir; Vaccine

$589,052

Immunosuppressive pathways and HIV reservoirs in tissues

Co-investigatorCIHR2019Project Grant

Principal investigators: Routy, Jean-Pierre

Keywords: Checkpoint; Functional Cure; Gut; Hiv Reservoirs; Immune Exhaustion; Immunosuppression; Inflammation; Lymph Nodes; Myeloid Cells

$780,300

Locking out HIV from CD4 T cells: A pilot study of the impact of anti a4b7 antibody (vedolizumab) on viral control following analytical treatment interruption

Co-investigatorCIHR2017Operating Grant: Innovative Biomedical and Clinical HIV/AIDS Research

Principal investigators: Routy, Jean-Pierre

Keywords: Anti-A4b7 Antibody; Cd4 T Cells; Clinical Trial; Gut Damage; Hiv Cure; Hiv Reservoirs; Hiv/Aids; Innovative Methods; Novel Technologies; Viral Rebound

$247,650

The lungs as HIV reservoirs: Interplay between disrupted respiratory immunity and Chronic Obstructive Pulmonary Disease (COPD)

Co-investigatorCIHR2016Project Grant

Principal investigators: Costiniuk, Cecilia T

Keywords: Chronic Obstructive Pulmonary Disease (Copd); Genetics Of Infectious Disease; Hiv Reservoirs; Lymphocytes; Macrophages; Pulmonary Immunity

$726,750

Impact of HIV infection and antiretroviral therapy on mucosal and systemic memory CD4 T cells

Co-investigatorCIHR2009Operating Grant - PA: HIV/AIDS Research Initiative - Biomedical/Clinical Stream

Principal investigators: Routy, Jean-Pierre

Keywords: Cd4 Memory Cells; Hiv/Aids; Microbial Translocation; Mucosal Immunity; Primary Hiv Infection; T Cell Activation

$750,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Nicolas Chomont

Research

Latest papers

Latest funding

Phenotypic analysis of productively SIV-infected cells in blood and lymphoid tissues of rhesus macaques.

Gaining biological insights through supervised data visualization.

Dynamics of HIV reservoirs following repeated anti-SARS-CoV-2 vaccination.

Innate antiviral and immune functions associated with the HIV reservoir decay after anti-PD-1 therapy.

The CanCURE Survey: Gender-Based Differences in HIV Cure Research Priorities.

No evidence of direct activation of human neutrophil responses by multivalent prefusion trimeric SARS-CoV-2 Spike protein ex vivo.

No Evidence of Direct Activation of Human Neutrophil Responses by Multivalent Prefusion Trimeric SARS-CoV-2 Spike Protein ex vivo.

Activation of CXCR3+ Tfh cells and B cells in lymph nodes during acute HIV-1 infection correlates with HIV-specific antibody development.

Altered memory CCR6+ Th17-polarised T-cell function and biology in people with HIV under successful antiretroviral therapy and HIV elite controllers.

Similar Viral and Immune Characteristics of Kaposi Sarcoma in ART-treated People Living With HIV and Older Patients With Classic Kaposi Sarcoma.

Frequent collaborators

Nicolas Chomont

Jean-Pierre Routy

Jean-Pierre Routy

Petronela Ancuta

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Mohammad-Ali Jenabian

Madeleine Durand

Madeleine Durand

Alexandre Prat

Catherine Larochelle

Carl Chartrand-Lefebvre

Christopher Power

Bertrand Routy

David Lessard

Talat Bessissow

Mario Ostrowski

Marina Klein

Wangari Tharao

Nathalie Grandvaux

Erwin Schurr

Nathalie Arbour

Ron Rosenes

Cecilia Costiniuk

Justin Sanders

Renee Masching

Renee Masching