Faculty profile

Moulay Alaoui-Jamali

ResearcherMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Moulay Alaoui-Jamali

Researcher

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
4 publications in the last five years, latest in 2025.
Principal investigator on 5 research grants (5 CIHR), most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Cancer Stem Cells Cell Differentiation Genomics Metabolism Mouse Cancer Models Pharmacology Preclinical Cancer Models Small Molecules

Latest papers

Current status of circulating tumor DNA and circulating cell alterations in HPV-associated head and neck cancer.
Oral oncology · 2025
Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer.
International journal of molecular sciences · 2024
Rethinking treatment paradigms: Neoadjuvant therapy and de-escalation strategies in HPV-positive head and neck cancer.
Critical reviews in oncology/hematology · 2024

All 12 publications

Latest funding

Characterization and therapeutic implication of a novel class of PKC-theta inhibitors selectively targeting undifferentiated cancer cells expressing stem cell markers
CIHR · 2021 · Nominated PI
$906,526
Bifunctional non-secosteroidal vitamin D analogues as novel cancer therapeutics
CIHR · 2016 · Co-investigator
$401,625
Triple Targeted Kinase Inhibitors Capable of Inhibiting Breast Cancer Metastases
CIHR · 2011 · Nominated PI
$160,000

All 8 grants and awards

12 publications.

Current status of circulating tumor DNA and circulating cell alterations in HPV-associated head and neck cancer.

Araujo M, Bouassaly J, Farshadi F, Hier M, Mascarella M, Mlynarek A, Alaoui-Jamali M, da Silva SD

Oral oncology2025

DOI: 10.1016/j.oraloncology.2025.107417 PMID: 40516153

Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer.

Muniz IAF, Araujo M, Bouassaly J, Farshadi F, Atique M, Esfahani K, Bonan PRF, Hier M, Mascarella M, Mlynarek A, Alaoui-Jamali M, Silva SDD

International journal of molecular sciences2024

DOI: 10.3390/ijms25074009 PMID: 38612819

Rethinking treatment paradigms: Neoadjuvant therapy and de-escalation strategies in HPV-positive head and neck cancer.

Bouassaly J, Karimi N, Kowalski LP, Sultanem K, Alaoui-Jamali M, Mlynarek A, Mascarella M, Hier M, Sadeghi N, da Silva SD

Critical reviews in oncology/hematology2024

DOI: 10.1016/j.critrevonc.2024.104326 PMID: 38479584

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

Krishnan R, Lapierre M, Gautreau B, Nixon KCJ, El Ghamrasni S, Patel PS, Hao J, Yerlici VT, Guturi KKN, St-Germain J, Mateo F, Saad A, Algouneh A, Earnshaw R, Shili D, Seitova A, Miller J, Khosraviani N, Penn A, Ho B, Sanchez O, Hande MP, Masson JY, Brown GW, Alaoui-Jamali M, Reynolds JJ, Arrowsmith C, Raught B, Pujana MA, Mekhail K, Stewart GS, Hakem A, Hakem R

Nucleic acids research2023

DOI: 10.1093/nar/gkad733 PMID: 37697435

A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability.

Sirois I, Aguilar-Mahecha A, Lafleur J, Fowler E, Vu V, Scriver M, Buchanan M, Chabot C, Ramanathan A, Balachandran B, Légaré S, Przybytkowski E, Lan C, Krzemien U, Cavallone L, Aleynikova O, Ferrario C, Guilbert MC, Benlimame N, Saad A, Alaoui-Jamali M, Saragovi HU, Josephy S, O'Flanagan C, Hursting SD, Richard VR, Zahedi RP, Borchers CH, Bareke E, Nabavi S, Tonellato P, Roy JA, Robidoux A, Marcus EA, Mihalcioiu C, Majewski J, Basik M

Molecular cancer research : MCR2019

DOI: 10.1158/1541-7786.mcr-19-0264 PMID: 31537618

MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ.

Guo Q, Li VZ, Nichol JN, Huang F, Yang W, Preston SEJ, Talat Z, Lefrère H, Yu H, Zhang G, Basik M, Gonçalves C, Zhan Y, Plourde D, Su J, Torres J, Marques M, Habyan SA, Bijian K, Amant F, Witcher M, Behbod F, McCaffrey L, Alaoui-Jamali M, Giannakopoulos NV, Brackstone M, Postovit LM, Del Rincón SV, Miller WH

Cancer research2019

DOI: 10.1158/0008-5472.can-18-1602 PMID: 30659022

Oncogenic activity of poly (ADP-ribose) glycohydrolase.

Marques M, Jangal M, Wang LC, Kazanets A, da Silva SD, Zhao T, Lovato A, Yu H, Jie S, Del Rincon S, Mackey J, Damaraju S, Alaoui-Jamali M, Witcher M

Oncogene2019

DOI: 10.1038/s41388-018-0568-6 PMID: 30459355

Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.

Li L, Guturi KKN, Gautreau B, Patel PS, Saad A, Morii M, Mateo F, Palomero L, Barbour H, Gomez A, Ng D, Kotlyar M, Pastrello C, Jackson HW, Khokha R, Jurisica I, Affar EB, Raught B, Sanchez O, Alaoui-Jamali M, Pujana MA, Hakem A, Hakem R

The Journal of clinical investigation2018

DOI: 10.1172/jci120401 PMID: 30222135

Efficacy of hybrid vitamin D receptor agonist/histone deacetylase inhibitors in vitamin D-resistant triple-negative 4T1 breast cancer.

Bijian K, Kaldre D, Wang TT, Su J, Bouttier M, Boucher A, Alaoui-Jamali M, White JH, Gleason JL

The Journal of steroid biochemistry and molecular biology2018

DOI: 10.1016/j.jsbmb.2017.08.010 PMID: 28847749

CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.

Hilmi K, Jangal M, Marques M, Zhao T, Saad A, Zhang C, Luo VM, Syme A, Rejon C, Yu Z, Krum A, Fabian MR, Richard S, Alaoui-Jamali M, Orthwein A, McCaffrey L, Witcher M

Science advances2017

DOI: 10.1126/sciadv.1601898 PMID: 28560323

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Moulay Alaoui-Jamali

Research

Latest papers

Latest funding

Current status of circulating tumor DNA and circulating cell alterations in HPV-associated head and neck cancer.

Therapeutic Advances and Challenges for the Management of HPV-Associated Oropharyngeal Cancer.

Rethinking treatment paradigms: Neoadjuvant therapy and de-escalation strategies in HPV-positive head and neck cancer.

RNF8 ubiquitylation of XRN2 facilitates R-loop resolution and restrains genomic instability in BRCA1 mutant cells.

A Unique Morphological Phenotype in Chemoresistant Triple-Negative Breast Cancer Reveals Metabolic Reprogramming and PLIN4 Expression as a Molecular Vulnerability.

MNK1/NODAL Signaling Promotes Invasive Progression of Breast Ductal Carcinoma In Situ.

Oncogenic activity of poly (ADP-ribose) glycohydrolase.

Ubiquitin ligase RNF8 suppresses Notch signaling to regulate mammary development and tumorigenesis.

Efficacy of hybrid vitamin D receptor agonist/histone deacetylase inhibitors in vitamin D-resistant triple-negative 4T1 breast cancer.

CTCF facilitates DNA double-strand break repair by enhancing homologous recombination repair.

Characterization and therapeutic implication of a novel class of PKC-theta inhibitors selectively targeting undifferentiated cancer cells expressing stem cell markers

Bifunctional non-secosteroidal vitamin D analogues as novel cancer therapeutics

Triple Targeted Kinase Inhibitors Capable of Inhibiting Breast Cancer Metastases

Investigation of the Filamin Signaling Network's Function in Cancer Progression

Molecular and Translational Studies of Filamin Signaling Network in Invasive Cancer

Discovery and Validation of Pharmacological Probes for Understanding Protein-Protein Interactions of Focal Adhesion Signalling in Invasive Cancer Cells

The CIHR/FRSQ Training Program in Cancer Research at McGill

Gene-specific prodrug targeting: optimization and potential clinical applications

Frequent collaborators

Michael Witcher

Brian Raught

Mark Basik

Luke McCaffrey

Nader Sadeghi

Sonia Del Rincon

Catalin Mihalcioiu

Jean-Yves Masson

Karim Mekhail

Sambasivarao Damaraju

Rama Khokha

Razqallah Hakem

Jacek Majewski

Muriel Brackstone

Lynne-Marie Postovit

Sonia Del Rincon

Cheryl Arrowsmith

Igor Jurisica