Faculty profile

Argel Aguilar Valles

ResearcherBiochemistryMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.

Argel Aguilar Valles

Researcher

Biochemistry

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
No publications since 2021.
Principal investigator on 1 research grant (1 CIHR), most recently in 2019.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

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Grants

Publications by year

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Signals and details

Research

Autism Spectrum Disorder Behavior Cannabinoids Cell Signalling Clinical Case Study Mental Health Mouse Models Neuroscience

Latest papers

Antidepressant actions of ketamine engage cell-specific translation via eIF4E.
Nature · 2021 · first author
Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.
Molecular autism · 2020
Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.
Nature communications · 2018 · first author

All 11 publications

Latest funding

Pharmacotherapeutic effects of cannabidiol (CBD) in autism spectrum disorder (ASD)
CIHR · 2019 · Principal investigator
$631,667

All 1 grants and awards

11 publications.

Antidepressant actions of ketamine engage cell-specific translation via eIF4E.

Aguilar-Valles A, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Khlaifia A, Skaleka A, Lopez-Canul M, Torres-Berrio A, Bermudez S, Rurak GM, Simard S, Salmaso N, Gobbi G, Lacaille JC, Sonenberg N

Nature2021First author

DOI: 10.1038/s41586-020-03047-0 PMID: 33328636

Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.

Haji N, Riebe I, Aguilar-Valles A, Artinian J, Laplante I, Lacaille JC

Molecular autism2020

DOI: 10.1186/s13229-020-00340-7 PMID: 32375878

Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.

Aguilar-Valles A, Haji N, De Gregorio D, Matta-Camacho E, Eslamizade MJ, Popic J, Sharma V, Cao R, Rummel C, Tanti A, Wiebe S, Nuñez N, Comai S, Nadon R, Luheshi G, Mechawar N, Turecki G, Lacaille JC, Gobbi G, Sonenberg N

Nature communications2018First author

DOI: 10.1038/s41467-018-04883-5 PMID: 29941989

Metformin ameliorates core deficits in a mouse model of fragile X syndrome.

Gantois I, Khoutorsky A, Popic J, Aguilar-Valles A, Freemantle E, Cao R, Sharma V, Pooters T, Nagpal A, Skalecka A, Truong VT, Wiebe S, Groves IA, Jafarnejad SM, Chapat C, McCullagh EA, Gamache K, Nader K, Lacaille JC, Gkogkas CG, Sonenberg N

Nature medicine2017

DOI: 10.1038/nm.4335 PMID: 28504725

Obesity, adipokines and neuroinflammation.

Aguilar-Valles A, Inoue W, Rummel C, Luheshi GN

Neuropharmacology2015First author

DOI: 10.1016/j.neuropharm.2014.12.023 PMID: 25582291

Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2.

Aguilar-Valles A, Matta-Camacho E, Khoutorsky A, Gkogkas C, Nader K, Lacaille JC, Sonenberg N

The Journal of neuroscience : the official journal of the Society for Neuroscience2015First author

DOI: 10.1523/jneurosci.4615-14.2015 PMID: 26245973

Time-dependent effects of localized inflammation on peripheral clock gene expression in rats.

Westfall S, Aguilar-Valles A, Mongrain V, Luheshi GN, Cermakian N

PloS one2013

DOI: 10.1371/journal.pone.0059808 PMID: 23527270

Leptin and interleukin-6 alter the function of mesolimbic dopamine neurons in a rodent model of prenatal inflammation.

Aguilar-Valles A, Jung S, Poole S, Flores C, Luheshi GN

Psychoneuroendocrinology2012First author

DOI: 10.1016/j.psyneuen.2011.11.003 PMID: 22133515

Alterations in cognitive function and behavioral response to amphetamine induced by prenatal inflammation are dependent on the stage of pregnancy.

Aguilar-Valles A, Luheshi GN

Psychoneuroendocrinology2011First author

DOI: 10.1016/j.psyneuen.2010.09.006 PMID: 20934257

Prenatal inflammation-induced hypoferremia alters dopamine function in the adult offspring in rat: relevance for schizophrenia.

Aguilar-Valles A, Flores C, Luheshi GN

PloS one2010First author

DOI: 10.1371/journal.pone.0010967 PMID: 20532043

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Argel Aguilar Valles

Research

Latest papers

Latest funding

Antidepressant actions of ketamine engage cell-specific translation via eIF4E.

Tsc1 haploinsufficiency in Nkx2.1 cells upregulates hippocampal interneuron mTORC1 activity, impairs pyramidal cell synaptic inhibition, and alters contextual fear discrimination and spatial working memory in mice.

Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E.

Metformin ameliorates core deficits in a mouse model of fragile X syndrome.

Obesity, adipokines and neuroinflammation.

Inhibition of Group I Metabotropic Glutamate Receptors Reverses Autistic-Like Phenotypes Caused by Deficiency of the Translation Repressor eIF4E Binding Protein 2.

Time-dependent effects of localized inflammation on peripheral clock gene expression in rats.

Leptin and interleukin-6 alter the function of mesolimbic dopamine neurons in a rodent model of prenatal inflammation.

Alterations in cognitive function and behavioral response to amphetamine induced by prenatal inflammation are dependent on the stage of pregnancy.

Prenatal inflammation-induced hypoferremia alters dopamine function in the adult offspring in rat: relevance for schizophrenia.

Pharmacotherapeutic effects of cannabidiol (CBD) in autism spectrum disorder (ASD)

Frequent collaborators

Jean-Claude Lacaille

Nahum Sonenberg

Karim Nader

Gabriella Gobbi

Cecilia Flores

Arkady Khoutorsky

Cecilia Flores

Argel Aguilar Valles

Natalina Salmaso

Wataru Inoue

Nicolas Cermakian

Giamal Luheshi

Naguib Mechawar

Sylvain Williams

Gustavo Turecki