This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Exploring the diagnostic accuracy of an HIV self-test optimized by a digital app-based solution: Results from a secondary data analysis of a field trial in South Africa.
PLOS digital health · 2025
Evidence on Digital HIV Self-Testing From Accuracy to Impact: Updated Systematic Review.
Journal of medical Internet research · 2025
Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction.
Science advances · 2024
Latest funding
- $933,300
Mechanisms and impact of mRNA alternative polyadenylation in the PI3K/AKT/PTEN cascade
CIHR · 2021 · Nominated PI
- $983,026
Functional genomics of microRNA polycistrons
CIHR · 2019 · Nominated PI
- $105,000
MicroRNAs as effectors of p53 and BRCA1 in high grade serous ovarian cancer
CIHR · 2018 · Supervisor
7 publications.
Exploring the diagnostic accuracy of an HIV self-test optimized by a digital app-based solution: Results from a secondary data analysis of a field trial in South Africa.
Beecroft A, Esmail A, Vaikla O, Duchaine T, Engel N, Liang C, Zhang Q, Dheda K, Pai NP
Evidence on Digital HIV Self-Testing From Accuracy to Impact: Updated Systematic Review.
Beecroft A, Vaikla O, Engel N, Duchaine T, Liang C, Pant Pai N
Repression of mRNA translation initiation by GIGYF1 via disrupting the eIF3-eIF4G1 interaction.
Choi JH, Luo J, Hesketh GG, Guo S, Pistofidis A, Ladak RJ, An Y, Naeli P, Alain T, Schmeing TM, Gingras AC, Duchaine T, Zhang X, Sonenberg N, Jafarnejad SM
The SARS-CoV-2 protein NSP2 enhances microRNA-mediated translational repression.
Naeli P, Zhang X, Snell PH, Chatterjee S, Kamran M, Ladak RJ, Orr N, Duchaine T, Sonenberg N, Jafarnejad SM
SARS-CoV-2 impairs interferon production via NSP2-induced repression of mRNA translation.
Xu Z, Choi JH, Dai DL, Luo J, Ladak RJ, Li Q, Wang Y, Zhang C, Wiebe S, Liu ACH, Ran X, Yang J, Naeli P, Garzia A, Zhou L, Mahmood N, Deng Q, Elaish M, Lin R, Mahal LK, Hobman TC, Pelletier J, Alain T, Vidal SM, Duchaine T, Mazhab-Jafari MT, Mao X, Jafarnejad SM, Sonenberg N
FLCN and AMPK Confer Resistance to Hyperosmotic Stress via Remodeling of Glycogen Stores.
Possik E, Ajisebutu A, Manteghi S, Gingras MC, Vijayaraghavan T, Flamand M, Coull B, Schmeisser K, Duchaine T, van Steensel M, Hall DH, Pause A
Fusion of TTYH1 with the C19MC microRNA cluster drives expression of a brain-specific DNMT3B isoform in the embryonal brain tumor ETMR
Kleinman CL, Gerges N, Papillon-Cavanagh S, Sin-Chan P, Pramatarova A, Quang D-AK, Adoue V, Busche S, Caron M, Djambazian H
Mechanisms and impact of mRNA alternative polyadenylation in the PI3K/AKT/PTEN cascade
Principal investigators: Duchaine, Thomas
Keywords: 3' -Untranslated Regions; Akt; Alternative Polyadenylation; Cancer; Cfim Complex; Crispr/Cas9 Genome Engineering; Microrna; Pi3k; Pten
Functional genomics of microRNA polycistrons
Principal investigators: Duchaine, Thomas
Keywords: 3'-Untranslated Regions; Dgcr8; Double-Stranded Rna; Drosha; Functional Genomics; Microrna; Mir-17~92; Rna Processing; Rna- Protein Interactions
MicroRNAs as effectors of p53 and BRCA1 in high grade serous ovarian cancer
Principal investigators: Tseng, Hsin Wei
Keywords: Crispr; Microrna; Ovarian Cancer; Sequencing
Ex vivo phenotyping of cells, organoids and embryos.
Principal investigators: Bouchard, Maxime
The NIP proteins: Inhibitors of nuclear RNA interference
Principal investigators: Duchaine, Thomas
MicroRNA cooperativity in mRNA translation repression and deadenylation, from genome edition to single-molecule imaging
Principal investigators: Duchaine, Thomas
Keywords: 3' Untranslated Region; Argonaute; C. Elegans; Cell-Free Assays; Deadenylase; Microrna; Post-Transcriptional Gene Regulation; Rna Processing; Rna-Binding Proteins; Single-Molecule Imaging
Making sense of antisense: the activities of RNA-dependent RNA polymerases in endogenous RNAi
Principal investigators: Duchaine, Thomas
Synergistic microRNA-binding sites, and 3' untranslated regions: a dialogue of silence
Principal investigators: Duchaine, Thomas
Keywords: 3' Untranslated Regions; C. Elegans; Cell Free Assays; Functional Screen; Micrornas; Mrna Deadenylation; Transgenic Reporters; Translation Repression
Deciphering the basis of mis-regulation of the miR17-92 cluster maturation in breast cancer
Principal investigators: Donayo, Ariel O
Keywords: Breast Cancer; Dicer; Drosha; Genetic Interaction; Mirna; Mirna Clusters; Mirna Regulation; Oncogenes; Small Rnas; Stromal Cells
Functional insights into the role of AIN-1/2 proteins in P bodies and miRNA-mediated silencing
Principal investigators: Wu, Edlyn
Keywords: Cell-Free Systems; Deadenylation; Development; Fluorescent In Situ Hybridization; Gene Regulation; Microrna-Mediated Silencing; Micrornas; Poly(A) Tail; Processing Bodies; Translation
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Nada Jabado and Jacek Majewski: 35 shared papers
- Nahum Sonenberg and Jerry Pelletier: 21 shared papers
- Nahum Sonenberg and Tommy Alain: 17 shared papers
- Nada Jabado and Annie Huang: 16 shared papers
- Adam Fleming and Nada Jabado: 13 shared papers
- Tomi Pastinen and Jacek Majewski: 10 shared papers
- Adam Fleming and Annie Huang: 6 shared papers
- Anne-Claude Gingras and Nahum Sonenberg: 6 shared papers
- Adam Fleming and Jacek Majewski: 5 shared papers
- Rongtuan Lin and Tommy Alain: 4 shared papers
- Anne-Claude Gingras and Tommy Alain: 3 shared papers
- Robert Sladek and Tomi Pastinen: 3 shared papers
- Nahum Sonenberg and Thomas Duchaine: 3 shared papers
- Nahum Sonenberg and Arnim Pause: 3 shared papers
- Annie Huang and Jacek Majewski: 3 shared papers
- Anne-Claude Gingras and Nada Jabado: 2 shared papers
- Anne-Claude Gingras and Chen Liang: 2 shared papers
- Anne-Claude Gingras and Arnim Pause: 2 shared papers
- Nahum Sonenberg and Rongtuan Lin: 2 shared papers
- Thomas Duchaine and Chen Liang: 2 shared papers
- Thomas Duchaine and Tommy Alain: 2 shared papers
- Nada Jabado and Tomi Pastinen: 2 shared papers
- Rongtuan Lin and Chen Liang: 2 shared papers
- Jerry Pelletier and Arnim Pause: 2 shared papers
- Adam Fleming and Robert Sladek: 1 shared paper
- Adam Fleming and Thomas Duchaine: 1 shared paper
- Anne-Claude Gingras and Thomas Duchaine: 1 shared paper
- Robert Sladek and Thomas Duchaine: 1 shared paper
- Robert Sladek and Qihuang Zhang: 1 shared paper
- Thomas Duchaine and Nada Jabado: 1 shared paper
- Thomas Duchaine and Tomi Pastinen: 1 shared paper
- Thomas Duchaine and Rongtuan Lin: 1 shared paper
- Thomas Duchaine and Annie Huang: 1 shared paper
- Thomas Duchaine and Jacek Majewski: 1 shared paper
- Thomas Duchaine and Jerry Pelletier: 1 shared paper
- Thomas Duchaine and Arnim Pause: 1 shared paper
- Thomas Duchaine and Qihuang Zhang: 1 shared paper
- Chen Liang and Qihuang Zhang: 1 shared paper
- Biochemistry
- Pediatrics
- Human Genetics
- AIDS Pathogenesis Unit
- Biochemistry, Microbiology and Immunology
- Department of Molecular Genetics
- Physics
- Other
Co-authors at McGill University, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Nahum Sonenberg
Biochemistry
3 shared papers, latest 2024
Tommy Alain
Biochemistry, Microbiology and Immunology
2 shared papers, latest 2024
Chen Liang
AIDS Pathogenesis Unit
2 shared papers, latest 2025
Rongtuan Lin
Medicine
1 shared papers, latest 2022
Annie Huang
Pediatrics
1 shared papers, latest 2014
Jacek Majewski
Human Genetics
1 shared papers, latest 2014
Jerry Pelletier
Biochemistry
1 shared papers, latest 2022
Arnim Pause
Biochemistry
1 shared papers, latest 2015
Nada Jabado
Pediatrics
1 shared papers, latest 2014
Qihuang Zhang
Faculty
1 shared papers, latest 2025
Tomi Pastinen
Human Genetics
1 shared papers, latest 2014
Adam Fleming
Pediatrics
1 shared papers, latest 2014
Anne-Claude Gingras
Department of Molecular Genetics
1 shared papers, latest 2024
Robert Sladek
Physics
1 shared papers, latest 2014
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