Faculty profile

Robert Sladek

ResearcherPhysicsMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Robert Sladek

Researcher

Physics

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
23 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 7 research grants (7 CIHR), most recently in 2014.
Supervised 2 trainees who won CIHR awards, most recently in 2015.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

902

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

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Signals and details

Research

Nanofluidics Circulating Tumor Cell Electron-Microscopy Graphene Nanochannel Single-Molecule Wet-Cell Beta Cell Physiology

Latest papers

Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.
Diabetes · 2026
Laypeople's Views on the Narrative Identity and Societal Treatment of Genetically Modified People.
Bioethics · 2026 · senior author
Benchmarking Bayesian Colocalization Methods in Validating Mendelian Randomization-identified Targets.
Genomics, proteomics & bioinformatics · 2026

All 58 publications

Latest funding

Prediabetes in Canadians 45-85 years of age and predictors of 3-year progression to diabetes: a longitudinal examination using data from the Canadian Longitudinal Study on Aging
CIHR · 2019 · Co-investigator
$70,000
Nanofluidic Wet-Cell for Genomic Analysis of Single Circulating Tumor Cells via Electron Microscopy
NSERC · 2015 · Co-investigator
$179,233
Developing a Novel Bioethics Framework for Genomic Engineering in Human Disease
CIHR · 2015 · Supervisor
$105,000

All 17 grants and awards

58 publications.

Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.

Wang N, DiCorpo DA, Zhang Y, Kleinbrink E, Arnett DK, Barnard J, Blangero J, Bowden DW, Carson AP, Chen YI, Chung MK, Curran JE, Darbar D, Duggirala R, Ellinor PT, Fatkin D, Fornage M, Heard-Costa N, He J, Hou L, Kardia SLR, Kooperberg C, Loos RJF, McManus DD, Mitchell BD, Minster RL, North KE, Psaty BM, Raffield LM, Redline S, Rich SS, Roden D, Rotter JI, Shoemaker MB, Smith JD, Van Wagoner DR, Aguet F, Ardlie K, Bis JC, Brody JA, Cade BE, Clish CB, de Vries PS, Floyd JS, Freedman BI, Gabriel S, Gerzsten RE, Goodarzi MO, Gu C, Guo X, Gupta N, Heckbert SR, Hsu S, Hung YJ, Kalyani RR, Kelly TN, Kinney GL, Li C, Liu S, Liu Y, Lloyd-Jones DM, Manson JE, Mathias RA, Mercader JM, Morrison AC, Naseri T, Onengut S, Palmer ND, Peyser PA, Qi Q, Raghavan S, Reiner AP, Rooney MR, Sevilla-Gonzalez M, Sarnowski C, Smith JD, Smith JA, Spartano NL, Tahir U, Taylor KD, Tobias DK, Tracy RP, Viali S, Wang H, Wood AC, Yanek LR, Zhao W, Zheng Y, Dupuis J, Liu CT, Sladek R, Wessel J, Meigs JB, Manning AK, NHLBI Trans-Omics for Precision Medicine (TOPMed) Consortium*

Diabetes2026

DOI: 10.2337/db25-0557 PMID: 42274313

Laypeople's Views on the Narrative Identity and Societal Treatment of Genetically Modified People.

So D, Joly Y, Sladek R

Bioethics2026Senior author

DOI: 10.1111/bioe.70051 PMID: 41230642

Benchmarking Bayesian Colocalization Methods in Validating Mendelian Randomization-identified Targets.

Zhang W, Yoshiji S, Sladek R, Dupuis J, Lu T

Genomics, proteomics & bioinformatics2026

DOI: 10.1093/gpbjnl/qzag087 PMID: 42613742

SpaTM: topic models for inferring spatially informed transcriptional programs.

Osakwe A, Dong W, Zhang Q, Sladek R, Li Y

Briefings in bioinformatics2025

DOI: 10.1093/bib/bbaf657 PMID: 41359801

Accounting for genetic effect heterogeneity in fine-mapping and improving power to detect gene-environment interactions with SharePro.

Zhang W, Sladek R, Li Y, Najafabadi H, Dupuis J

Nature communications2024

DOI: 10.1038/s41467-024-53818-w PMID: 39478020

Case-Base Neural Network: Survival analysis with time-varying, higher-order interactions.

Islam J, Turgeon M, Sladek R, Bhatnagar S

Machine learning with applications2024

DOI: 10.1016/j.mlwa.2024.100535 PMID: 39802089

Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes.

Kwak SH, Hernandez-Cancela RB, DiCorpo DA, Condon DE, Merino J, Wu P, Brody JA, Yao J, Guo X, Ahmadizar F, Meyer M, Sincan M, Mercader JM, Lee S, Haessler J, Vy HMT, Lin Z, Armstrong ND, Gu S, Tsao NL, Lange LA, Wang N, Wiggins KL, Trompet S, Liu S, Loos RJF, Judy R, Schroeder PH, Hasbani NR, Bos MM, Morrison AC, Jackson RD, Reiner AP, Manson JE, Chaudhary NS, Carmichael LK, Chen YI, Taylor KD, Ghanbari M, van Meurs J, Pitsillides AN, Psaty BM, Noordam R, Do R, Park KS, Jukema JW, Kavousi M, Correa A, Rich SS, Damrauer SM, Hajek C, Cho NH, Irvin MR, Pankow JS, Nadkarni GN, Sladek R, Goodarzi MO, Florez JC, Chasman DI, Heckbert SR, Kooperberg C, Dupuis J, Malhotra R, de Vries PS, Liu CT, Rotter JI, Meigs JB, Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) Consortium

Diabetes care2024

DOI: 10.2337/dc23-2274 PMID: 38652672

Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.

Yu V, Yong F, Marta A, Khadayate S, Osakwe A, Bhattacharya S, Varghese SS, Chabosseau P, Tabibi SM, Chen K, Georgiadou E, Parveen N, Suleiman M, Stamoulis Z, Marselli L, De Luca C, Tesi M, Ostinelli G, Delgadillo-Silva L, Wu X, Hatanaka Y, Montoya A, Elliott J, Patel B, Demchenko N, Whilding C, Hajkova P, Shliaha P, Kramer H, Ali Y, Marchetti P, Sladek R, Dhawan S, Withers DJ, Rutter GA, Millership SJ

Diabetologia2024

DOI: 10.1007/s00125-024-06123-6 PMID: 38512414

SharePro: an accurate and efficient genetic colocalization method accounting for multiple causal signals.

Zhang W, Lu T, Sladek R, Li Y, Najafabadi H, Dupuis J

Bioinformatics (Oxford, England)2024

DOI: 10.1093/bioinformatics/btae295 PMID: 38688586

Silencing ANGPTL8 reduces mouse preadipocyte differentiation and insulin signaling.

Ghosh A, Leung YH, Yu J, Sladek R, Chénier I, Oppong AK, Peyot ML, Madiraju SRM, Al-Khairi I, Thanaraj TA, Abubaker J, Al-Mulla F, Prentki M, Abu-Farha M

Biochimica et biophysica acta. Molecular and cell biology of lipids2024

DOI: 10.1016/j.bbalip.2024.159461 PMID: 38272177

Prediabetes in Canadians 45-85 years of age and predictors of 3-year progression to diabetes: a longitudinal examination using data from the Canadian Longitudinal Study on Aging

Co-investigatorCIHR2019Catalyst Grant: Analysis of CLSA Data

Principal investigators: Rahme, Elham

Keywords: Canrisk; Genetic; Hemoglobin A1c; Machine Learning; Prediabetes; Risk Factors; Type 2 Diabetes

$70,000

Nanofluidic Wet-Cell for Genomic Analysis of Single Circulating Tumor Cells via Electron Microscopy

Co-investigatorNSERC2015Collaborative Health Research Projects

Principal investigators: Reisner, Walter

$179,233

Developing a Novel Bioethics Framework for Genomic Engineering in Human Disease

SupervisorCIHR2015Doctoral Award - Frederick Banting and Charles Best Canada Graduate Scholarships

Principal investigators: So, Derek M

Keywords: Bioethics; Canadian Healthcare; Descriptive Ethics; Genome Editing; Health Policy; Human Genetics; Narrative Ethics; Prenatal Gene Therapy; Qualitative Data; Science Policy

$105,000

Nanofluidic Wet-Cell for Genomic Analysis of Single Circulating Tumor Cells via Electron Microscopy

Principal investigatorCIHR2014Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Reisner, Walter W; Hilke, Michael; Riazalhosseini, Yasser; Sladek, Robert G

Keywords: Circulating Tumor Cell; Electron-Microscopy; Graphene; Nanochannel; Nanofluidics; Single-Molecule; Wet-Cell

$358,467

Nanoconfinement based single-cell cytogenetic platform for pre-/post-implantation genetic diagnosis

Co-investigatorNSERC2013Collaborative Health Research Projects

Principal investigators: Reisner, Walter

$219,185

Nanoconfinement Based Single-Cell Cytogenetic Platform for Pre-/Post-Implantation Genetic Diagnosis

Principal investigatorCIHR2012Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Reisner, Walter W; Ao, Asangla; Leslie, Sabrina R; Sladek, Robert G

Keywords: Convex-Lens Imposed Confinement (Clic); Cytogenetics; Nanofluidics; Pre-Implantation Genetic Diagnosis; Pre-Implantation Genetic Screening

$219,185

Integrated proteomics and genomics approach to characterize a risk locus for type 2 diabetes

Nominated PICIHR2012Operating Grant

Principal investigators: Sladek, Robert G

Keywords: Beta Cell Physiology; Common Genetic Variants; Diabetes Genetics; Diabetes Pathogenesis; Functional Genomics; Gene Expression; Protein Networks; Proteomics; Rare Genetic Variants; Transcription Factors

$576,454

Multidimensional Epigenomics Mapping Centre (EMC) at McGill

Co-investigatorCIHR2011CEEHRC Epigenomics Platform - Epigenomic Mapping Centres (EMC)

Principal investigators: Lathrop, Mark; Meaney, Michael J; Pastinen, Tomi

Keywords: Epigenomics

$5,665,000

Genetics and genomics of the antimycobacterial activity of vitamin D.

Co-investigatorCIHR2010Operating Grant

Principal investigators: White, John H; Behr, Marcel A

Keywords: Bioinformatics; Chip-Seq; Cyp24 Inhibitors; Gene Expression Profiling; Innate Immunity; Mycobacterium Tuberculosis; Target Validation; Vitamin D

$823,750

Equipment for the development of nitride-based nanoscale electronic, photonic, and biosensing devices on a si platform

Co-investigatorNSERC2010Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Mi, Zetian

$113,115

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Robert Sladek

Research

Latest papers

Latest funding

Colocalization of eQTLs With Type 2 Diabetes and Glycemic Traits Using Whole-Genome Sequences in Diverse Populations From the NHLBI Trans-Omics in Precision Medicine (TOPMed) Program.

Laypeople's Views on the Narrative Identity and Societal Treatment of Genetically Modified People.

Benchmarking Bayesian Colocalization Methods in Validating Mendelian Randomization-identified Targets.

SpaTM: topic models for inferring spatially informed transcriptional programs.

Accounting for genetic effect heterogeneity in fine-mapping and improving power to detect gene-environment interactions with SharePro.

Case-Base Neural Network: Survival analysis with time-varying, higher-order interactions.

Time-to-Event Genome-Wide Association Study for Incident Cardiovascular Disease in People With Type 2 Diabetes.

Differential CpG methylation at Nnat in the early establishment of beta cell heterogeneity.

SharePro: an accurate and efficient genetic colocalization method accounting for multiple causal signals.

Silencing ANGPTL8 reduces mouse preadipocyte differentiation and insulin signaling.

Prediabetes in Canadians 45-85 years of age and predictors of 3-year progression to diabetes: a longitudinal examination using data from the Canadian Longitudinal Study on Aging

Nanofluidic Wet-Cell for Genomic Analysis of Single Circulating Tumor Cells via Electron Microscopy

Developing a Novel Bioethics Framework for Genomic Engineering in Human Disease

Nanofluidic Wet-Cell for Genomic Analysis of Single Circulating Tumor Cells via Electron Microscopy

Nanoconfinement based single-cell cytogenetic platform for pre-/post-implantation genetic diagnosis

Nanoconfinement Based Single-Cell Cytogenetic Platform for Pre-/Post-Implantation Genetic Diagnosis

Integrated proteomics and genomics approach to characterize a risk locus for type 2 diabetes

Multidimensional Epigenomics Mapping Centre (EMC) at McGill

Genetics and genomics of the antimycobacterial activity of vitamin D.

Equipment for the development of nitride-based nanoscale electronic, photonic, and biosensing devices on a si platform

Frequent collaborators

Marc Prentki

Yue Li

Yann Joly

Tomi Pastinen

Sara Mahshid

Danuta Radzioch

Vincent Mooser

Constantin Polychronakos

Walter Reisner

Elin Grundberg

Annie Huang

Jacek Majewski

Mark Walker

Maya Saleh

Jean-Jacques Lebrun

Angela Pearson

Martin Olivier

Mark Walker

Sahir Bhatnagar

Qihuang Zhang

Guillaume Pare

Marie Eva Pigeyre

Adam Fleming

Guillaume Lettre

Martin Olivier

Stefano Stifani