Faculty profile

William Muller

ResearcherMedicineMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

William Muller

Researcher

Medicine

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
2 publications in the last five years, latest in 2023.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 20 research grants (20 CIHR), most recently in 2025.
Supervisor on 5 trainee awards (5 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Breast Cancer Metastasis Erbb2 Her2 Ezh2 Biomarkers Epigenetics Genetic Engineered Mouse Models

Latest papers

Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells.
PloS one · 2023
Tailoring therapies to counter the divergent immune landscapes of breast cancer.
Frontiers in cell and developmental biology · 2023 · senior author
Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects.
EMBO molecular medicine · 2021

All 10 publications

Latest funding

Elucidating the function of EZH2 in modulating cellular plasticity through control of estrogen receptor expression and driving tumor recurrence in breast cancer
CIHR · 2025 · Supervisor
$120,000
Investigating the role of the DEPTOR protein in the initiation and progression of breast cancer
CIHR · 2025 · Supervisor
$35,000
Unlocking the Power of Trained Immunity in Cancer
CIHR · 2025 · Principal investigator
$1,500,000

All 29 grants and awards

10 publications.

Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells.

Mohammad AH, Couture F, Gamache I, Chen O, El-Assaad W, Abdel-Malak N, Kwiatkowska A, Muller W, Day R, Teodoro JG

PloS one2023

DOI: 10.1371/journal.pone.0288622 PMID: 37463144

Tailoring therapies to counter the divergent immune landscapes of breast cancer.

Attalla S, Taifour T, Muller W

Frontiers in cell and developmental biology2023Senior author

DOI: 10.3389/fcell.2023.1111796 PMID: 36910138

Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects.

Sadek J, Hall DT, Colalillo B, Omer A, Tremblay AK, Sanguin-Gendreau V, Muller W, Di Marco S, Bianchi ME, Gallouzi IE

EMBO molecular medicine2021

DOI: 10.15252/emmm.202013591 PMID: 34096686

Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo.

Attalla S, Taifour T, Bui T, Muller W

Oncogene2021Senior author

DOI: 10.1038/s41388-020-01560-0 PMID: 33235291

Elevated V-ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer.

Mohammad AH, Kim SH, Bertos N, El-Assaad W, Nandi I, Smith H, Yang J, Chen OJ, Gamache I, Rao T, Gagnon B, Gruosso T, Tremblay ML, Sonenberg N, Guiot MC, Muller W, Park M, Teodoro JG

Molecular cancer research : MCR2020

DOI: 10.1158/1541-7786.mcr-20-0088 PMID: 32587106

V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss.

Mohammad AH, Assadian S, Couture F, Lefebvre KJ, El-Assaad W, Barrès V, Ouellet V, Boulay PL, Yang J, Latour M, Furic L, Muller W, Sonenberg N, Mes-Masson AM, Saad F, Day R, Teodoro JG

Oncotarget2019

DOI: 10.18632/oncotarget.27075 PMID: 31452834

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.

Hulea L, Gravel SP, Morita M, Cargnello M, Uchenunu O, Im YK, Lehuédé C, Ma EH, Leibovitch M, McLaughlan S, Blouin MJ, Parisotto M, Papavasiliou V, Lavoie C, Larsson O, Ohh M, Ferreira T, Greenwood C, Bridon G, Avizonis D, Ferbeyre G, Siegel P, Jones RG, Muller W, Ursini-Siegel J, St-Pierre J, Pollak M, Topisirovic I

Cell metabolism2018

DOI: 10.1016/j.cmet.2018.09.001 PMID: 30244971

Tumoral Vitamin D Synthesis by CYP27B1 1-α-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-κB Modulation.

Li J, Luco AL, Ochietti B, Fadhil I, Camirand A, Reinhardt TA, St-Arnaud R, Muller W, Kremer R

Endocrinology2016

DOI: 10.1210/en.2015-1824 PMID: 27119753

Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer.

Rossdeutscher L, Li J, Luco AL, Fadhil I, Ochietti B, Camirand A, Huang DC, Reinhardt TA, Muller W, Kremer R

Cancer prevention research (Philadelphia, Pa.)2015

DOI: 10.1158/1940-6207.capr-14-0110 PMID: 25468832

Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle.

Chen D, Goswami CP, Burnett RM, Anjanappa M, Bhat-Nakshatri P, Muller W, Nakshatri H

Cancer research2014

DOI: 10.1158/0008-5472.can-13-2817 PMID: 24980554

Something wrong or missing on this profile? Suggest a correction

William Muller

Research

Latest papers

Latest funding

Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells.

Tailoring therapies to counter the divergent immune landscapes of breast cancer.

Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects.

Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo.

Elevated V-ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer.

V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss.

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.

Tumoral Vitamin D Synthesis by CYP27B1 1-α-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-κB Modulation.

Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer.

Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle.

Elucidating the function of EZH2 in modulating cellular plasticity through control of estrogen receptor expression and driving tumor recurrence in breast cancer

Investigating the role of the DEPTOR protein in the initiation and progression of breast cancer

Unlocking the Power of Trained Immunity in Cancer

Incretin-mimetic drugs for cancer prevention: Mechanisms and clinical potential

Targeting EZH2 in breast cancer: Role of epigenetic modification in modulating breast cancer cell plasticity.

Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.

Investigating the Chi3l1-neutrophil axis in breast cancer progression

Identifying the molecular and environmental factors involved in promoting escape from breast cancer dormancy.

Chi3L1 (YKL-40) plays a multifaceted role in modulating tumor immune microenvironment during breast cancer progression.

Identification of Stat1 signaling pathway(s) involved in mediating tumor escape from immune surveillance.

Frequent collaborators

Richard Kremer

Robert Day

Nahum Sonenberg

Simon-Pierre Gravel

Peter Siegel

Julie St-Pierre

Bruno Gagnon

Celia Greenwood

Laura Hulea

Michael Pollak

Morag Park

Ivan Topisirovic

Michael Ohh

William Muller

Research

Latest papers

Latest funding

Cleavage of the V-ATPase associated prorenin receptor is mediated by PACE4 and is essential for growth of prostate cancer cells.

Tailoring therapies to counter the divergent immune landscapes of breast cancer.

Pharmacological or genetic inhibition of iNOS prevents cachexia-mediated muscle wasting and its associated metabolism defects.

Insights from transgenic mouse models of PyMT-induced breast cancer: recapitulating human breast cancer progression in vivo.

Elevated V-ATPase Activity Following PTEN Loss Is Required for Enhanced Oncogenic Signaling in Breast Cancer.

V-ATPase-associated prorenin receptor is upregulated in prostate cancer after PTEN loss.

Translational and HIF-1&#x3b1;-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.

Tumoral Vitamin D Synthesis by CYP27B1 1-&#x3b1;-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-&#x3ba;B Modulation.

Chemoprevention activity of 25-hydroxyvitamin D in the MMTV-PyMT mouse model of breast cancer.

Cancer affects microRNA expression, release, and function in cardiac and skeletal muscle.

Frequent collaborators

Richard Kremer

Robert Day

Nahum Sonenberg

Simon-Pierre Gravel

Peter Siegel

Julie St-Pierre

Bruno Gagnon

Celia Greenwood

Laura Hulea

Michael Pollak

Morag Park

Ivan Topisirovic

Michael Ohh

Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides.

Tumoral Vitamin D Synthesis by CYP27B1 1-α-Hydroxylase Delays Mammary Tumor Progression in the PyMT-MMTV Mouse Model and Its Action Involves NF-κB Modulation.