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Julie St-Pierre

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Associate ProfessorBiochemistry, Microbiology and ImmunologyUniversity of Ottawa

Julie St-Pierre

Associate Professor

Biochemistry, Microbiology and Immunology

Faculty of Medicine

University of Ottawa

Ottawa, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
14 publications in the last five years, latest in 2026.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 4 research grants (4 CIHR), most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Read how they describe their research on their University of Ottawa profile.

Metabolism Cancer Metastasis Breast Cancer Mitochondria Crc

Latest papers

Rapamycin-induced fatty liver in mice is attenuated by chloroquine co-treatment in an ERRα-dependent manner.
The Journal of endocrinology · 2026
Rethinking mitochondria as a target for cancer therapy.
Trends in molecular medicine · 2026 · senior author
Dyslipidemia in children: diagnosis, evaluation, and management.
Paediatrics & child health · 2026

All 27 publications

Latest funding

Single Cell Metabolomics: Uncovering Metabolic Heterogeneity and Revealing Novel Aspects of Tissue Architecture
SSHRC · 2023 · Co-investigator
$249,276
Genetic models of the metabolic regulator PGC-1alpha in breast cancer
CIHR · 2021 · Nominated PI
$1,013,625
Genetic models of the metabolic regulator PGC-1alpha in breast cancer
CIHR · 2021 · Nominated PI
$100,000

All 6 grants and awards

27 publications.

Rapamycin-induced fatty liver in mice is attenuated by chloroquine co-treatment in an ERRα-dependent manner.

B'chir W, Dufour CR, Andrzejewski S, St-Pierre J, Scholtes C, Giguère V

The Journal of endocrinology2026

DOI: 10.1530/joe-26-0176 PMID: 42544714

Rethinking mitochondria as a target for cancer therapy.

Minarrieta L, St-Pierre J

Trends in molecular medicine2026Senior author

DOI: 10.1016/j.molmed.2025.12.002 PMID: 41760516

Dyslipidemia in children: diagnosis, evaluation, and management.

Khoury M, Bigras JL, Cummings EA, Harris KC, Hegele RA, Henderson M, Morrison KM, St-Pierre J, Wong PD, McCrindle BW

Paediatrics & child health2026

DOI: 10.1093/pch/pxag021 PMID: 42266258

Mitochondrial elongation impairs breast cancer metastasis.

Minarrieta L, Annis MG, Audet-Delage Y, Kuasne H, Pacis A, St-Louis C, Nowakowski A, Biondini M, Khacho M, Park M, Siegel PM, St-Pierre J

Science advances2024Senior author

DOI: 10.1126/sciadv.adm8212 PMID: 39504368

AMPK-mediated regulation of endogenous cholesterol synthesis does not affect atherosclerosis in a murine Pcsk9-AAV model.

Smith TKT, Ghorbani P, LeBlond ND, Nunes JRC, O'Dwyer C, Ambursley N, Fong-McMaster C, Minarrieta L, Burkovsky LA, El-Hakim R, Trzaskalski NA, Locatelli CAA, Stotts C, Pember C, Rayner KJ, Kemp BE, Loh K, Harper ME, Mulvihill EE, St-Pierre J, Fullerton MD

Atherosclerosis2024

DOI: 10.1016/j.atherosclerosis.2024.117608 PMID: 38880706

Metastatic breast cancer cells are metabolically reprogrammed to maintain redox homeostasis during metastasis.

Biondini M, Lehuédé C, Tabariès S, Annis MG, Pacis A, Ma EH, Tam C, Hsu BE, Audet-Delage Y, Abu-Thuraia A, Girondel C, Sabourin V, Totten SP, de Sá Tavares Russo M, Bridon G, Avizonis D, Guiot MC, St-Pierre J, Ursini-Siegel J, Jones R, Siegel PM

Redox biology2024

DOI: 10.1016/j.redox.2024.103276 PMID: 39053265

p66ShcA promotes malignant breast cancer phenotypes by alleviating energetic and oxidative stress.

Lewis K, La Selva R, Maldonado E, Annis MG, Najyb O, Cepeda Cañedo E, Totten S, Hébert S, Sabourin V, Mirabelli C, Ciccolini E, Lehuédé C, Choinière L, Russo M, Avizonis D, Park M, St-Pierre J, Kleinman CL, Siegel PM, Ursini-Siegel J

Redox biology2024

DOI: 10.1016/j.redox.2024.103028 PMID: 38211442

Spatiotemporal modeling of chemoresistance evolution in breast tumors uncovers dependencies on SLC38A7 and SLC46A1.

Audet-Delage Y, St-Louis C, Minarrieta L, McGuirk S, Kurreal I, Annis MG, Mer AS, Siegel PM, St-Pierre J

Cell reports2023Senior author

DOI: 10.1016/j.celrep.2023.113191 PMID: 37792528

Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.

Ghorbani P, Kim SY, Smith TKT, Minarrieta L, Robert-Gostlin V, Kilgour MK, Ilijevska M, Alecu I, Snider SA, Margison KD, Nunes JRC, Woo D, Pember C, O'Dwyer C, Ouellette J, Kotchetkov P, St-Pierre J, Bennett SAL, Lacoste B, Blais A, Nair MG, Fullerton MD

PLoS pathogens2023

DOI: 10.1371/journal.ppat.1011658 PMID: 37747879

The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma.

Findlay S, Nair R, Merrill RA, Kaiser Z, Cajelot A, Aryanpour Z, Heath J, St-Louis C, Papadopoli D, Topisirovic I, St-Pierre J, Sebag M, Kesarwala AH, Hulea L, Taylor EB, Shanmugam M, Orthwein A

Blood advances2023

DOI: 10.1182/bloodadvances.2022008345 PMID: 36920785

Profile data last refreshed on September 25, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Julie St-Pierre

Research

Latest papers

Latest funding

Rapamycin-induced fatty liver in mice is attenuated by chloroquine co-treatment in an ERR&#x3b1;-dependent manner.

Rethinking mitochondria as a target for cancer therapy.

Dyslipidemia in children: diagnosis, evaluation, and management.

Mitochondrial elongation impairs breast cancer metastasis.

AMPK-mediated regulation of endogenous cholesterol synthesis does not affect atherosclerosis in a murine Pcsk9-AAV model.

Metastatic breast cancer cells are metabolically reprogrammed to maintain redox homeostasis during metastasis.

p66ShcA promotes malignant breast cancer phenotypes by alleviating energetic and oxidative stress.

Spatiotemporal modeling of chemoresistance evolution in breast tumors uncovers dependencies on SLC38A7 and SLC46A1.

Choline metabolism underpins macrophage IL-4 polarization and RELM&#x3b1; up-regulation in helminth infection.

The mitochondrial pyruvate carrier complex potentiates the efficacy of proteasome inhibitors in multiple myeloma.

Single Cell Metabolomics: Uncovering Metabolic Heterogeneity and Revealing Novel Aspects of Tissue Architecture

Genetic models of the metabolic regulator PGC-1alpha in breast cancer

Genetic models of the metabolic regulator PGC-1alpha in breast cancer

Metabolomics Advanced Training and International Exchange (CREATE-MATRIX)

The impact of mitochondrial dynamics on breast cancer metastasis

Canada Research Chair - tier 1

Frequent collaborators

Julie St-Pierre

Shawn McGuirk

Ivan Topisirovic

Ivan Topisirovic

Michael Pollak

Morag Park

Morag Park

Simon-Pierre Gravel

Laura Hulea

Sidong Huang

Mary-Ellen Harper

Mark Basik

Mireille Khacho

Jenna Sykes

Celia Greenwood

Kevin Petrecca

Peter Siegel

Ming-Sound Tsao

Alexandre Blais

Jacek Majewski

Alexandre Orthwein

Arnim Pause

Baptiste Lacoste

Damien D'Amours

Kevin Petrecca

Geoffrey Liu

Rapamycin-induced fatty liver in mice is attenuated by chloroquine co-treatment in an ERRα-dependent manner.

Choline metabolism underpins macrophage IL-4 polarization and RELMα up-regulation in helminth infection.