Lili-Naz Hazrati, University of Toronto

Research

Brca1 Dna Damage Dna Repair Inflammation Mild Traumatic Brain Injury Ovariectomy Post-Concussive Syndrome Senescence

Latest papers

Brain pathology and symptoms linked to concussion history: beyond chronic traumatic encephalopathy.
Brain communications · 2024 · senior author
CNS tumor with BCOR internal tandem duplication
Child's Nervous System · 2023 · first author
Chronic traumatic encephalopathy neuropathologic change is uncommon in men who played amateur American football.
Frontiers in neurology · 2023

All 80 publications

Latest funding

Impact of myelin changes on behavioural recovery after mild traumatic brain injury
CIHR · 2021 · Co-investigator
$753,525
Long-term effects of mild traumatic brain injury through premature cellular senescence
CIHR · 2019 · Nominated PI
$1,067,176
Contribution of Mid-life Comorbidities to Alzheimer's Disease
CIHR · 2016 · Co-investigator
$1,002,150

All 6 grants and awards

80 publications.

01

Brain pathology and symptoms linked to concussion history: beyond chronic traumatic encephalopathy.

Taskina D, Zhu C, Schwab N, Hazrati LN

Brain communications2024Senior author

DOI: 10.1093/braincomms/fcad314 PMID: 38560515

02

CNS tumor with BCOR internal tandem duplication

Hazrati L-N, Monajemzadeh M, Habibi Z, Moeini B, Safavi M

Child's Nervous System20233 citationsFirst author

DOI: 10.1007/s00381-022-05796-x

03

Chronic traumatic encephalopathy neuropathologic change is uncommon in men who played amateur American football.

Iverson GL, Jamshidi P, Fisher-Hubbard AO, Deep-Soboslay A, Hyde TM, Kleinman JE, deJong JL, Shepherd CE, Hazrati LN, Castellani RJ

Frontiers in neurology2023

DOI: 10.3389/fneur.2023.1143882 PMID: 37404944

04

The pathological potential of ependymal cells in mild traumatic brain injury.

Nelles DG, Hazrati LN

Frontiers in cellular neuroscience2023Senior author

DOI: 10.3389/fncel.2023.1216420 PMID: 37396927

05

BRCA1 heterozygosity promotes DNA damage-induced senescence in a sex-specific manner following repeated mild traumatic brain injury.

Leung E, Taskina D, Schwab N, Hazrati LN

Frontiers in neuroscience2023Senior author

DOI: 10.3389/fnins.2023.1225226 PMID: 37638313

06

Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects.

Chong JX, Childers MC, Marvin CT, Marcello AJ, Gonorazky H, Hazrati LN, Dowling JJ, Amrani FA, Alanay Y, Nieto Y, Gabriel MÁM, Aylsworth AS, Buckingham KJ, Shively KM, Sommers O, Anderson K, University of Washington Center for Mendelian Genomics, University of Washington Center for Rare Disease Research, Regnier M, Bamshad MJ

medRxiv : the preprint server for health sciences2023

DOI: 10.1101/2023.03.07.23286862 PMID: 36945405

07

Variants in ACTC1 underlie distal arthrogryposis accompanied by congenital heart defects.

Chong JX, Childers MC, Marvin CT, Marcello AJ, Gonorazky H, Hazrati LN, Dowling JJ, Al Amrani F, Alanay Y, Nieto Y, Gabriel MÁM, Aylsworth AS, Buckingham KJ, Shively KM, Sommers O, Anderson K, University of Washington Center for Mendelian Genomics, University of Washington Center for Rare Disease Research, Regnier M, Bamshad MJ

HGG advances2023

DOI: 10.1016/j.xhgg.2023.100213 PMID: 37457373

08

Titin related myopathy with ophthalmoplegia. A novel phenotype.

Alawneh I, Yuki KE, Amburgey K, Yoon G, Dowling JJ, Hazrati LN, Gonorazky H

Neuromuscular disorders : NMD2023

DOI: 10.1016/j.nmd.2023.05.003 PMID: 37393749

09

Evidence of sex differences in cellular senescence.

Ng M, Hazrati LN

Neurobiology of aging2022Senior author

DOI: 10.1016/j.neurobiolaging.2022.08.014 PMID: 36166919

10

Ependymal cells and neurodegenerative disease: outcomes of compromised ependymal barrier function.

Nelles DG, Hazrati LN

Brain communications2022Senior author

DOI: 10.1093/braincomms/fcac288 PMID: 36415662

Impact of myelin changes on behavioural recovery after mild traumatic brain injury

Co-investigatorCIHR2021Project Grant

Principal investigators: Wheeler, Anne L

Keywords: Electron Microscopy; Histology; Mild Traumatic Brain Injury; Mouse Behaviour; Mri; Myelin; Oligodendrocyte Precursor Cells; Oligodendrocytes; White Matter

$753,525

Long-term effects of mild traumatic brain injury through premature cellular senescence

Nominated PICIHR2019Project Grant

Principal investigators: Hazrati, Lili-Naz; Mclaurin, Joanne; Stefanovic, Bojana; Wells, Peter G

Keywords: Brca1; Dna Damage; Dna Repair; Inflammation; Mild Traumatic Brain Injury; Ovariectomy; Post-Concussive Syndrome; Senescence; Senolytic

$1,067,176

Contribution of Mid-life Comorbidities to Alzheimer's Disease

Co-investigatorCIHR2016Project Grant

Principal investigators: Mclaurin, Joanne; Lambe, Evelyn K; Stefanovic, Bojana

Keywords: Alzheimer'S Disease; Animal Models Of Disease; Comorbidities

$1,002,150

Multimodal Assessment For Predicting Specific Pathological Substrate in Frontotemporal Lobar Degeneration

Co-investigatorCIHR2014Operating Grant

Principal investigators: Tartaglia, Maria Carmela

Keywords: Biomarkers; Cerebrospinal Fluid; Frontotemporal Dementia; Frontotemporal Lobar Degeneration; Imaging; Neuropathology; Tau; Tdp-43

$572,884

Assessing the effects of remote traumatic brain injury on brain aging

Co-investigatorCIHR2013Operating Grant

Principal investigators: Levine, Brian T

Keywords: Aging; Alzheimer'S Disease; Biomarkers; Cognitive Functioning; Concussion; Dementia; Genetics; Neuropsychology; Traumatic Brain Injury

$745,484

Synaptic loss in neurodegenerative diseases: Identification of structural and molecular events leading to the collapse of the synapse

Nominated PICIHR2008CIHR Clinician Scientist - Phase 1

Principal investigators: Hazrati, Lili-Naz

Keywords: Dendritic Spine; In Vivo Imaging; Neurodegeneration; Synapse

$172,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Frequent collaborators

Uri Tabori and Cynthia Hawkins: 122 shared papers
Uri Tabori and Eric Bouffet: 117 shared papers
Vijay Ramaswamy and Eric Bouffet: 107 shared papers
Cynthia Hawkins and Eric Bouffet: 92 shared papers
Eric Bouffet and Ute Bartels: 81 shared papers
Uri Tabori and Vijay Ramaswamy: 80 shared papers
Annie Huang and Eric Bouffet: 67 shared papers
Cynthia Hawkins and Vijay Ramaswamy: 61 shared papers
Uri Tabori and Ute Bartels: 57 shared papers
Uri Tabori and Annie Huang: 56 shared papers
Cynthia Hawkins and Ute Bartels: 49 shared papers
Annie Huang and Ute Bartels: 46 shared papers
Gelareh Zadeh and Kenneth Aldape: 30 shared papers
Cynthia Hawkins and James Rutka: 16 shared papers
Gelareh Zadeh and Alireza Mansouri: 15 shared papers
Connie Marras and Anthony Lang: 15 shared papers
Connie Marras and Ekaterina Rogaeva: 11 shared papers
James Drake and Elysa Widjaja: 11 shared papers
Gelareh Zadeh and Cynthia Hawkins: 10 shared papers
James Drake and Eric Bouffet: 10 shared papers
James Drake and Ute Bartels: 10 shared papers
James Drake and James Rutka: 8 shared papers
James Rutka and Eric Bouffet: 8 shared papers
Elysa Widjaja and James Rutka: 6 shared papers
Kenneth Aldape and Vijay Ramaswamy: 6 shared papers
Anthony Lang and Ekaterina Rogaeva: 6 shared papers
Lili-Naz Hazrati and Eric Bouffet: 6 shared papers
Uri Tabori and Kenneth Aldape: 5 shared papers
Uri Tabori and Lili-Naz Hazrati: 5 shared papers
Gelareh Zadeh and Phedias Diamandis: 5 shared papers
James Drake and Abhaya Kulkarni: 5 shared papers
Annie Huang and Lili-Naz Hazrati: 5 shared papers
Uri Tabori and Abhaya Kulkarni: 4 shared papers
Cynthia Hawkins and Lili-Naz Hazrati: 4 shared papers
James Drake and Shelly Weiss: 4 shared papers
David Mikulis and Ekaterina Rogaeva: 4 shared papers
Elysa Widjaja and Shelly Weiss: 4 shared papers
James Rutka and Lili-Naz Hazrati: 4 shared papers
Vijay Ramaswamy and Lili-Naz Hazrati: 4 shared papers
Lili-Naz Hazrati and Ute Bartels: 4 shared papers
Eric Bouffet and Abhaya Kulkarni: 4 shared papers
Connie Marras and Lili-Naz Hazrati: 3 shared papers
David Mikulis and Lili-Naz Hazrati: 3 shared papers
Kenneth Aldape and Phedias Diamandis: 3 shared papers
Ekaterina Rogaeva and Lili-Naz Hazrati: 3 shared papers
Gelareh Zadeh and Lili-Naz Hazrati: 2 shared papers
Cynthia Hawkins and Shelly Weiss: 2 shared papers
James Drake and Lili-Naz Hazrati: 2 shared papers
Elysa Widjaja and Lili-Naz Hazrati: 2 shared papers
Joanne McLaurin and Lili-Naz Hazrati: 2 shared papers
Kenneth Aldape and Lili-Naz Hazrati: 2 shared papers
Phedias Diamandis and Lili-Naz Hazrati: 2 shared papers
Lili-Naz Hazrati and Clement Hamani: 2 shared papers
Lili-Naz Hazrati and Shelly Weiss: 2 shared papers
Gelareh Zadeh and David Mikulis: 1 shared paper
Anne-Marie Laberge and Lili-Naz Hazrati: 1 shared paper
Andrew Emili and Joanne McLaurin: 1 shared paper
Andrew Emili and Lili-Naz Hazrati: 1 shared paper
Elysa Widjaja and Alireza Mansouri: 1 shared paper
Joanne McLaurin and Ekaterina Rogaeva: 1 shared paper
Kenneth Aldape and Alireza Mansouri: 1 shared paper
Anthony Lang and Lili-Naz Hazrati: 1 shared paper
Lili-Naz Hazrati and Alireza Mansouri: 1 shared paper
Lili-Naz Hazrati and Abhaya Kulkarni: 1 shared paper
Lili-Naz Hazrati and Anahi Perlas: 1 shared paper

Department of Paediatrics
Pediatrics
Department of Laboratory Medicine and Pathobiology
Department of Surgery
Medical Imaging
Neurosurgery
Genetics and Genome Biology
Other

Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.

Eric Bouffet

Department of Paediatrics

6 shared papers, latest 2021

Uri Tabori

Genetics and Genome Biology

5 shared papers, latest 2021

Annie Huang

Pediatrics

5 shared papers, latest 2021

Ute Bartels

Faculty

4 shared papers, latest 2021

James Rutka

Department of Surgery

4 shared papers, latest 2021

Vijay Ramaswamy

Developmental Stem Cell Biology

4 shared papers, latest 2021

Cynthia Hawkins

Department of Laboratory Medicine and Pathobiology

4 shared papers, latest 2020

Ekaterina Rogaeva

Tanz Centre for Research in Neurodegenerative Diseases

3 shared papers, latest 2013

Connie Marras

Medicine/Neurology

3 shared papers, latest 2015

David Mikulis

Medical Imaging

3 shared papers, latest 2022

Clement Hamani

Faculty

2 shared papers, latest 2015

Shelly Weiss

Department of Paediatrics

2 shared papers, latest 2012

Elysa Widjaja

Medical Imaging

2 shared papers, latest 2019

Joanne McLaurin

Department of Laboratory Medicine and Pathobiology

2 shared papers, latest 2015

James Drake

Surgery

2 shared papers, latest 2020

Gelareh Zadeh

Neurosurgery

2 shared papers, latest 2021

Phedias Diamandis

Laboratory Medicine and Pathology

2 shared papers, latest 2013

Kenneth Aldape

Neurosurgery

2 shared papers, latest 2020

Abhaya Kulkarni

Department of Surgery

1 shared papers, latest 2020

Francois Mathieu

Department of Surgery

1 shared papers, latest 2018

Anahi Perlas

Department of Anesthesiology and Pain Medicine

1 shared papers, latest 2013

Mark Bernstein

Department of Surgery

1 shared papers, latest 2016

Pablo Rusjan

Faculty

1 shared papers, latest 2022

Alireza Mansouri

Faculty

1 shared papers, latest 2016

Jagdish Butany

Department of Laboratory Medicine and Pathobiology

1 shared papers, latest 2009

Valérie Larouche

Pediatric Hematology/Oncology

1 shared papers, latest 2020

Erika Tavares

Pediatrics

1 shared papers, latest 2020

Gerhard Multhaup

Pharmacology and Therapeutics

1 shared papers, latest 2015

Maryam Monajemzadeh

Pathology & Molecular Medicine

1 shared papers, latest 2023

David Westaway

Medicine

1 shared papers, latest 2012

Peter ST GEORGE-HYSLOP

Medicine

1 shared papers, latest 2012

Write to this professor

A short, specific email works best. This draft uses one of their recent papers; replace the parts in brackets with your own details before sending.

Applying for

Paper to mentionMention their CIHR grant from 2019

Subject: Prospective PhD student: Brca1 Dear Professor Hazrati, My name is [your name], and I am a [your current degree or role] at [your institution]. I am applying for a PhD position starting in [term and year]. I read your paper "Brain pathology and symptoms linked to concussion history: beyond chronic traumatic encephalopathy." (2024), and it connects closely to my own work on [your research topic]. [One or two sentences on what you did and what you learned.] I also saw your CIHR-funded project "Long-term effects of mild traumatic brain injury through premature cellular senescence" (2019), and I would be glad to contribute to work in that direction. Are you accepting new PhD students for [term and year]? I have attached my CV and transcripts, and I would be glad to talk at a time that suits you. Thank you for your time. Kind regards, [your name]