Faculty profile

Alexandre Dubrac

ResearcherPathologie et biologie cellulaireUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Alexandre Dubrac

Researcher

Pathologie et biologie cellulaire

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
8 publications in the last five years, latest in 2026.
Senior (last) author on 1 recent paper, a sign of leading a research group.
Principal investigator on 5 research grants (3 CIHR, 2 NSERC), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

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Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Tgfb Angiogenesis Endothelial Cell Alk1 Bmp Brain Arteriovenous Malformation Hereditary Hemorrhagic Telangiectasia Ischemique Stroke

Latest papers

Correction: MCC links Wnt/PCP signaling to endothelial polarity and vascular remodeling.
Angiogenesis · 2026
MCC links Wnt/PCP signaling to endothelial polarity and vascular remodeling.
Angiogenesis · 2026
Mapping neuro-vascular unit communications reveals distinct angiogenic programs across developing mouse brain regions.
Nature communications · 2026 · senior author

All 10 publications

Latest funding

Unveiling Therapeutic Insights into Brain Arteriovenous Malformations: Targeting cKIT Signaling in Hereditary Hemorrhagic Telangiectasia Type 2
CIHR · 2024 · Nominated PI
$1,166,626
Role of endothelial glycolysis in pericyte recruitment and function
NSERC · 2022 · Principal investigator
$12,500
The role of the TGFB-SOX9 signaling pathway in brain angiogenesis
CIHR · 2022 · Nominated PI
$826,200

All 5 grants and awards

10 publications.

Correction: MCC links Wnt/PCP signaling to endothelial polarity and vascular remodeling.

Delobel V, Jaspard B, Salami M, Camoin M, Peghaire C, Vaurs J, Boulestreau R, Kohonen-Corish M, Dubrac A, Couffinhal T, Duplàa C

Angiogenesis2026

DOI: 10.1007/s10456-026-10086-0 PMID: 42762340

MCC links Wnt/PCP signaling to endothelial polarity and vascular remodeling.

Delobel V, Jaspard B, Salami M, Camoin M, Peghaire C, Vaurs J, Boulestreau R, Kohonen-Corish M, Dubrac A, Couffinhal T, Duplàa C

Angiogenesis2026

DOI: 10.1007/s10456-026-10068-2 PMID: 42295508

Mapping neuro-vascular unit communications reveals distinct angiogenic programs across developing mouse brain regions.

Bizou M, Drapé E, Cagnone G, Howard JP, Irgolitsch F, Leclerc S, Chen MX, Boisseau B, Robillard I, Ruiz M, Lesage F, Joyal JS, Andelfinger G, Dubrac A

Nature communications2026Senior author

DOI: 10.1038/s41467-026-73373-w PMID: 42173924

The spatiotemporal dynamics of postnatal vascularization in the mouse brain.

de Launoit E, Skriabine S, Doumazane E, Bizou M, Pommé R, Lienhard G, Rajot D, Mikhailenko A, Vieites-Prado A, Lannes M, Fabiano N, Mathé L, Cagnone G, Mouton L, Santin MD, Candelier S, Gaspar P, Rousseau CV, Dubrac A, Renier N

Cell2026

DOI: 10.1016/j.cell.2026.03.013 PMID: 41985458

Metabolic reprogramming of the neovascular niche promotes regenerative angiogenesis in proliferative retinopathy.

Cagnone G, Pundir S, Betus C, Agnihotri T, Ren A, -Kim JS, Harvey NR, Heckel E, Chen MX, Situ A, Gaub P, Kim N, Das A, Leclerc S, Wünnemann F, Berillon L, Andelfinger G, Crespo-Garcia S, Dubrac A, Rezende FA, Clish CB, Maranda B, Rivera JC, Smith LEH, Sapieha P, Joyal JS

Nature communications2025

DOI: 10.1038/s41467-025-60061-4 PMID: 40562775

RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth.

Tetik-Elsherbiny N, Elsherbiny A, Setya A, Gahn J, Tang Y, Gupta P, Dou Y, Serke H, Wieland T, Dubrac A, Heineke J, Potente M, Cordero J, Ola R, Dobreva G

Nature cardiovascular research2024

DOI: 10.1038/s44161-024-00546-5 PMID: 39322771

ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis.

El Bakkouri Y, Chidiac R, Delisle C, Corriveau J, Cagnone G, Gaonac'h-Lovejoy V, Chin A, Lécuyer É, Angers S, Joyal JS, Topisirovic I, Hulea L, Dubrac A, Gratton JP

Nature communications2024

DOI: 10.1038/s41467-024-48852-7 PMID: 38782923

Role of endothelial PDGFB in arterio-venous malformations pathogenesis.

Lin Y, Gahn J, Banerjee K, Dobreva G, Singhal M, Dubrac A, Ola R

Angiogenesis2024

DOI: 10.1007/s10456-023-09900-w PMID: 38070064

Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation.

Zarkada G, Howard JP, Xiao X, Park H, Bizou M, Leclerc S, Künzel SE, Boisseau B, Li J, Cagnone G, Joyal JS, Andelfinger G, Eichmann A, Dubrac A

Developmental cell2021Senior author

DOI: 10.1016/j.devcel.2021.06.021 PMID: 34273276

Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.

Crespo-Garcia S, Tsuruda PR, Dejda A, Ryan RD, Fournier F, Chaney SY, Pilon F, Dogan T, Cagnone G, Patel P, Buscarlet M, Dasgupta S, Girouard G, Rao SR, Wilson AM, O'Brien R, Juneau R, Guber V, Dubrac A, Beausejour C, Armstrong S, Mallette FA, Yohn CB, Joyal JS, Marquess D, Beltran PJ, Sapieha P

Cell metabolism2021

DOI: 10.1016/j.cmet.2021.01.011 PMID: 33548171

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Alexandre Dubrac

Research

Latest papers

Latest funding

Correction: MCC links Wnt/PCP signaling to endothelial polarity and vascular remodeling.

MCC links Wnt/PCP signaling to endothelial polarity and vascular remodeling.

Mapping neuro-vascular unit communications reveals distinct angiogenic programs across developing mouse brain regions.

The spatiotemporal dynamics of postnatal vascularization in the mouse brain.

Metabolic reprogramming of the neovascular niche promotes regenerative angiogenesis in proliferative retinopathy.

RNF20-mediated transcriptional pausing and VEGFA splicing orchestrate vessel growth.

ZO-1 interacts with YB-1 in endothelial cells to regulate stress granule formation during angiogenesis.

Role of endothelial PDGFB in arterio-venous malformations pathogenesis.

Specialized endothelial tip cells guide neuroretina vascularization and blood-retina-barrier formation.

Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition.

Unveiling Therapeutic Insights into Brain Arteriovenous Malformations: Targeting cKIT Signaling in Hereditary Hemorrhagic Telangiectasia Type 2

Role of endothelial glycolysis in pericyte recruitment and function

The role of the TGFB-SOX9 signaling pathway in brain angiogenesis

Role of endothelial glycolysis in pericyte recruitment and function

ALK5-PAR6A signaling pathway regulates endothelial cells proliferation and vascular leakage

Frequent collaborators

Przemyslaw Sapieha

Przemyslaw Sapieha

Gregor Andelfinger

Jean-Sébastien Joyal

Jean-Philippe Gratton

Ivan Topisirovic

Ivan Topisirovic

Stephane Angers

Laura Hulea

Christian Beausejour