Faculty profile

Samuel David

ResearcherCentre for Research in NeurosciencesMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Samuel David

Researcher

Centre for Research in Neurosciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
7 publications in the last five years, latest in 2024.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (8 CIHR, 1 NSERC), most recently in 2019.
Supervisor on 2 trainee awards (2 CIHR), most recently in 2012.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Multiple Sclerosis Demyelination Gene And Protein Expression Iron Metabolism Microscopy Mmunohistochemistry Neurodegeneration Cell Death

Latest papers

Tlr4 Deletion Modulates Cytokine and Extracellular Matrix Expression in Chronic Spinal Cord Injury, Leading to Improved Secondary Damage and Functional Recovery.
The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024 · senior author
Ferroptosis inhibitor improves outcome after early and delayed treatment in mild spinal cord injury.
Acta neuropathologica · 2024 · senior author
Ceruloplasmin-Deficient Mice Show Dysregulation of Lipid Metabolism in Liver and Adipose Tissue Reduced by a Protein Replacement.
International journal of molecular sciences · 2023

All 65 publications

Latest funding

Ferroptosis-mediated damage in Chronic EAE: implications for Progressive MS
CIHR · 2019 · Nominated PI
$742,052
Mechanisms controlling iron efflux and accumulation in the nervous system: role in health, injury and disease
CIHR · 2015 · Nominated PI
$819,008
11th Annual Neuroinflammation Symposium, Montreal
CIHR · 2015 · Nominated PI
$9,500

All 13 grants and awards

65 publications.

Tlr4 Deletion Modulates Cytokine and Extracellular Matrix Expression in Chronic Spinal Cord Injury, Leading to Improved Secondary Damage and Functional Recovery.

Ryan F, Francos-Quijorna I, Hernández-Mir G, Aquino C, Schlapbach R, Bradbury EJ, David S

The Journal of neuroscience : the official journal of the Society for Neuroscience2024Senior author

DOI: 10.1523/jneurosci.0778-23.2023 PMID: 38326029

Ferroptosis inhibitor improves outcome after early and delayed treatment in mild spinal cord injury.

Ryan F, Blex C, Ngo TD, Kopp MA, Michalke B, Venkataramani V, Curran L, Schwab JM, Ruprecht K, Otto C, Jhelum P, Kroner A, David S

Acta neuropathologica2024Senior author

DOI: 10.1007/s00401-024-02758-2 PMID: 38907771

Ceruloplasmin-Deficient Mice Show Dysregulation of Lipid Metabolism in Liver and Adipose Tissue Reduced by a Protein Replacement.

Raia S, Conti A, Zanardi A, Ferrini B, Scotti GM, Gilberti E, De Palma G, David S, Alessio M

International journal of molecular sciences2023

DOI: 10.3390/ijms24021150 PMID: 36674661

Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS.

Jhelum P, Zandee S, Ryan F, Zarruk JG, Michalke B, Venkataramani V, Curran L, Klement W, Prat A, David S

Acta neuropathologica communications2023Senior author

DOI: 10.1186/s40478-023-01617-7 PMID: 37491291

Ferroptosis in Neurological Disease.

David S, Ryan F, Jhelum P, Kroner A

The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry2023First author

DOI: 10.1177/10738584221100183 PMID: 35678019

Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders.

David S, Jhelum P, Ryan F, Jeong SY, Kroner A

Antioxidants & redox signaling2022First author

DOI: 10.1089/ars.2021.0218 PMID: 34569265

Ferroptosis: copper-iron connection in cuprizone-induced demyelination.

Jhelum P, David S

Neural regeneration research2022Senior author

DOI: 10.4103/1673-5374.314300 PMID: 34100434

Schwann Cells Provide Iron to Axonal Mitochondria and Its Role in Nerve Regeneration.

Mietto BS, Jhelum P, Schulz K, David S

The Journal of neuroscience : the official journal of the Society for Neuroscience2021Senior author

DOI: 10.1523/jneurosci.0900-21.2021 PMID: 34272312

Bioactive Lipid Mediators in the Initiation and Resolution of Inflammation after Spinal Cord Injury.

David S, López-Vales R

Neuroscience2021First author

DOI: 10.1016/j.neuroscience.2021.04.026 PMID: 33951502

Neuroimmunological therapies for treating spinal cord injury: Evidence and future perspectives.

Chio JCT, Xu KJ, Popovich P, David S, Fehlings MG

Experimental neurology2021

DOI: 10.1016/j.expneurol.2021.113704 PMID: 33745920

Ferroptosis-mediated damage in Chronic EAE: implications for Progressive MS

Nominated PICIHR2019Project Grant

Principal investigators: David, Samuel

Keywords: Cell Death; Ferroptosis,; Iron; Iron Chelation; Lipid Peroxidation; Mouse Model Of Ms; Multiple Sclerosis; Myelin Loss; Oligodendrocytes; Oxidative Damage

$742,052

Mechanisms controlling iron efflux and accumulation in the nervous system: role in health, injury and disease

Nominated PICIHR2015Operating Grant

Principal investigators: David, Samuel

Keywords: Cns Injury; Demyelination; Gene And Protein Expression; Iron Metabolism; Microscopy; Mmunohistochemistry; Multiple Sclerosis; Nerve Regeneration; Neurodegeneration; Transgenic Mice

$819,008

11th Annual Neuroinflammation Symposium, Montreal

Nominated PICIHR2015Planning and Dissemination Grant - Institute Community Support

Principal investigators: David, Samuel

Keywords: Imaging Of Brain Inflammation In Humans; Inflammation In Peripheral Nerve Injury; Inflammation In Spinal Cord Injury; Inflammation In The Nervous System; Multipe Sclerosis; Viral Infection Mediated Demyelinating Disease

$9,500

Rapidly-Gelling, Guanosine 5' Diphosphate-Crosslinked Injectable Chitosan Sponges to Promote Oligodendrocyte Progenitor Cells' Differentiation Post-Spinal Cord Injuries

Co-investigatorCIHR2013Collaborative Health Research Projects (NSERC partnered)

Principal investigators: Tabrizian, Maryam; Antel, Jack P

Keywords: Bdnf/Igf-1 Or Nt-3 Delivery; Biomedical Engineering 1102; Biomedical Materials 1902; Biomedical Technology 1901; Chitosan Guanosine 5'-Diphosphate (Gdp)-Crosslinked Sponge; Contused Spinal Cord In A Mouse Model; Injectable Sponge; Life Sciences 1201; Rat & Human Oligodendrocyte Progenitor Cells Differentiation; Remyelination Post-Spinal Cord Injury

$277,440

Mechanisms controlling macrophage and microglia polarization in the nervous system: implications for neural repair

Nominated PICIHR2013Operating Grant

Principal investigators: David, Samuel

Keywords: Chemokines And Cytokines; Demyelination; Gene And Protein Expression; Inflammation In Spinal Cord; Iron Metabolism; Microscopy; Mmunohistochemistry; Multiple Sclerosis; Neurodegeneration; Peripheral Nerve Regeneration

$855,011

The origin, polarization state and function of macrophages in central nervous system injury

SupervisorCIHR2012CIHR Fellowship

Principal investigators: Greenhalgh, Andrew D

Keywords: Inflammation; Macrophages; Microglia/Monocytes; Spinal Cord Injury

$135,000

Confocal laser scanning microscope for high-resolution, 3-dimensional imaging in neuroscience

Co-investigatorNSERC2011Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Carbonetto, Salvatore

$139,519

Molecular control of myelin breakdown and phagocytosis after nerve injury

SupervisorCIHR2009CIHR Fellowship

Principal investigators: Kroner-Milsch, Antje

Keywords: Central Nervous System; Elisa; Molecular Control; Nerve Injury; Peripheral Nervous System; Phagocytosis; Phospholipase; Regeneration; Rt-Pcr; Western Blot

$105,000

Molecular control of iron homeostasis in the central nervous system

Nominated PICIHR2009Operating Grant

Principal investigators: David, Samuel

Keywords: Ferroxidases; Free Radicals; Immunohistochemistry; Iron; Knockout And Mutant Mice; Western Blotting

$919,584

CIHR Emerging Team in Central and Peripheral Nervous System Demyelination

Nominated PICIHR2009Emerging Team Grant: Regenerative Medicine and Nanomedicine - LOI

Principal investigators: David, Samuel; Bennett, Steffany A; Stys, Peter K

Keywords: Demyelination; Imaging; Multiple Sclerosis; Natural Compound Libraries; Peripheral Nerve Injury; Spinal Cord Injury

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Samuel David

Research

Latest papers

Latest funding

Tlr4 Deletion Modulates Cytokine and Extracellular Matrix Expression in Chronic Spinal Cord Injury, Leading to Improved Secondary Damage and Functional Recovery.

Ferroptosis inhibitor improves outcome after early and delayed treatment in mild spinal cord injury.

Ceruloplasmin-Deficient Mice Show Dysregulation of Lipid Metabolism in Liver and Adipose Tissue Reduced by a Protein Replacement.

Ferroptosis induces detrimental effects in chronic EAE and its implications for progressive MS.

Ferroptosis in Neurological Disease.

Dysregulation of Iron Homeostasis in the Central Nervous System and the Role of Ferroptosis in Neurodegenerative Disorders.

Ferroptosis: copper-iron connection in cuprizone-induced demyelination.

Schwann Cells Provide Iron to Axonal Mitochondria and Its Role in Nerve Regeneration.

Bioactive Lipid Mediators in the Initiation and Resolution of Inflammation after Spinal Cord Injury.

Neuroimmunological therapies for treating spinal cord injury: Evidence and future perspectives.

Ferroptosis-mediated damage in Chronic EAE: implications for Progressive MS

Mechanisms controlling iron efflux and accumulation in the nervous system: role in health, injury and disease

11th Annual Neuroinflammation Symposium, Montreal

Rapidly-Gelling, Guanosine 5' Diphosphate-Crosslinked Injectable Chitosan Sponges to Promote Oligodendrocyte Progenitor Cells' Differentiation Post-Spinal Cord Injuries

Mechanisms controlling macrophage and microglia polarization in the nervous system: implications for neural repair

The origin, polarization state and function of macrophages in central nervous system injury

Confocal laser scanning microscope for high-resolution, 3-dimensional imaging in neuroscience

Molecular control of myelin breakdown and phagocytosis after nerve injury

Molecular control of iron homeostasis in the central nervous system

CIHR Emerging Team in Central and Peripheral Nervous System Demyelination

Frequent collaborators

Danuta Radzioch

Ji Zhang

Alexandre Prat

Jack Antel

Nathalie Arbour

Arthur Brown

Manuela Santos

Stefano Stifani

Wolfram Tetzlaff

Edith Hamel

Nicolas Bisson