Faculty profile

Nicolas Bisson

ResearcherUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Nicolas Bisson

Researcher

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
8 publications in the last five years, latest in 2025.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (6 CIHR, 4 NSERC), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Cell Signaling Protein Interactions Proteomics Tyrosine Kinase Crc Adaptor Proteins Breast Cancer Mass Spectrometry

Latest papers

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling.
Molecular oncology · 2025
EGFR Phosphorylates and Associates with EFNB1 to Regulate Cell Adhesion to Fibronectin.
Molecular & cellular proteomics : MCP · 2025 · senior author
Adapting to change: resolving the dynamic and dual roles of NCK1 and NCK2.
The Biochemical journal · 2024 · senior author

All 31 publications

Latest funding

Deciphering how oncogenic tyrosine kinase receptors rewire cell signaling networks via SRC-Homology (SH) 3 domain phosphorylation
CIHR · 2024 · Nominated PI
$1,028,925
Understanding the specificity and regulation of NCK adaptor proteins
NSERC · 2024 · Principal investigator
$63,000
Canada Research Chairs - Tier 2
CIHR · 2020 · Nominated PI
$500,000

All 11 grants and awards

31 publications.

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling.

Lau HR, Smith HS, Alural B, Martin CE, New LA, Tilak M, Banerjee SL, Robeson HN, Bisson N, Gingras AC, Lalonde J, Jones N

Molecular oncology2025

DOI: 10.1002/1878-0261.70022 PMID: 40152177

EGFR Phosphorylates and Associates with EFNB1 to Regulate Cell Adhesion to Fibronectin.

Osornio-Hernández AI, Chartier FJM, Schuehle TL, Banerjee SL, Elowe S, Laprise P, Freywald A, Laurin M, Bisson N

Molecular & cellular proteomics : MCP2025Senior author

DOI: 10.1016/j.mcpro.2025.101027 PMID: 40619000

Adapting to change: resolving the dynamic and dual roles of NCK1 and NCK2.

Teyssier V, Williamson CR, Shata E, Rosen SP, Jones N, Bisson N

The Biochemical journal2024Senior author

DOI: 10.1042/bcj20230232 PMID: 39392452

Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR.

Hanover G, Vizeacoumar FS, Banerjee SL, Nair R, Dahiya R, Osornio-Hernandez AI, Morales AM, Freywald T, Himanen JP, Toosi BM, Bisson N, Vizeacoumar FJ, Freywald A

Cell reports2023

DOI: 10.1016/j.celrep.2023.112670 PMID: 37392382

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

El Zawily A, Vizeacoumar FS, Dahiya R, Banerjee SL, Bhanumathy KK, Elhasasna H, Hanover G, Sharpe JC, Sanchez MG, Greidanus P, Stacey RG, Moon KM, Alexandrov I, Himanen JP, Nikolov DB, Fonge H, White AP, Foster LJ, Wang B, Toosi BM, Bisson N, Mirzabekov TA, Vizeacoumar FJ, Freywald A

Clinical cancer research : an official journal of the American Association for Cancer Research2023

DOI: 10.1158/1078-0432.ccr-22-2535 PMID: 36976175

SRC homology 3 domains: multifaceted binding modules.

Dionne U, Percival LJ, Chartier FJM, Landry CR, Bisson N

Trends in biochemical sciences2022Senior author

DOI: 10.1016/j.tibs.2022.04.005 PMID: 35562294

Complementary Nck1/2 Signaling in Podocytes Controls α Actinin-4-Mediated Actin Organization, Adhesion, and Basement Membrane Composition.

Martin CE, Phippen NJ, Keyvani Chahi A, Tilak M, Banerjee SL, Lu P, New LA, Williamson CR, Platt MJ, Simpson JA, Krendel M, Bisson N, Gingras AC, Jones N

Journal of the American Society of Nephrology : JASN2022

DOI: 10.1681/asn.2021101343 PMID: 35906089

EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks.

Banerjee SL, Lessard F, Chartier FJM, Jacquet K, Osornio-Hernandez AI, Teyssier V, Ghani K, Lavoie N, Lavoie JN, Caruso M, Laprise P, Elowe S, Lambert JP, Bisson N

Cell reports2022Senior author

DOI: 10.1016/j.celrep.2022.111031 PMID: 35793621

Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling.

M Gagné L, Morin N, Lavoie N, Bisson N, Lambert JP, Mallette FA, Huot MÉ

The Journal of biological chemistry2021

DOI: 10.1016/j.jbc.2021.101291 PMID: 34634301

Protein context shapes the specificity of SH3 domain-mediated interactions in vivo.

Dionne U, Bourgault É, Dubé AK, Bradley D, Chartier FJM, Dandage R, Dibyachintan S, Després PC, Gish GD, Pham NTH, Létourneau M, Lambert JP, Doucet N, Bisson N, Landry CR

Nature communications2021

DOI: 10.1038/s41467-021-21873-2 PMID: 33712617

Deciphering how oncogenic tyrosine kinase receptors rewire cell signaling networks via SRC-Homology (SH) 3 domain phosphorylation

Nominated PICIHR2024Project Grant

Principal investigators: Bisson, Nicolas

Keywords: Cancer; Cell Signaling; Mouse Models Of Cancer; Non-Small Cell Lung Carcinoma; Protein Interactions; Proteomics; Signaling Networks; Src-Homology (Sh) Domains; Tyrosine Kinase; Tyrosine Phosphorylation

$1,028,925

Understanding the specificity and regulation of NCK adaptor proteins

Principal investigatorNSERC2024Discovery Grants Program - Individual

Principal investigators: Bisson, Nicolas

Keywords: cell signalling; protein-protein interactions; adaptor proteins; modular protein domains; cytokinesis; signalling networks; tyrosine phosphorylation; protein biochemistry; disordered proteins; tyrosine kinases

$63,000

Canada Research Chairs - Tier 2

Nominated PICIHR2020Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Bisson, Nicolas

Keywords: Crc

$500,000

High throughput analysis of protein interactions and modifications using peptide arrays

Principal investigatorNSERC2019Research Tools and Instruments

Principal investigators: Bisson, Nicolas

$146,864

Understanding the specificity and regulation of NCK adaptor proteins

Principal investigatorNSERC2018Discovery Grants Program - Individual

Principal investigators: Bisson, Nicolas

$300,000

Regulation of oncogenic receptor tyrosine kinase signalling networks by protein phosphorylation.

Nominated PICIHR2018Project Grant

Principal investigators: Bisson, Nicolas

Keywords: Cell Signalling; Membrane Receptors; Oncogenes; Phosphorylation; Protein Interactions; Proteomics; Tyrosine Kinase

$906,525

Canada Research Chair Tier 2

Nominated PICIHR2014Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Bisson, Nicolas

Keywords: Crc

$500,000

Signalisation Québec 2014

Co-investigatorCIHR2013Dissemination Events - Priority Announcement: Cancer Research

Principal investigators: Laprise, Patrick

Keywords: Biologie Du Cancer; Identification De Cibles Thérapeutiques En Oncologie; Signalisation Intracellulaire

$25,000

Targeted Proteomics Analysis of the Adaptor Protein Grb2 Signaling Network Dynamics in Breast Cancer.

Nominated PICIHR2013Operating Grant

Principal investigators: Bisson, Nicolas

Keywords: Adaptor Proteins; Breast Cancer; Cell Signaling; Mass Spectrometry; Molecular Biology; Personalized Medicine; Protein Interaction Networks; Protein Phosphorylation; Systems Biology; Targeted Proteomics

$658,336

Understanding the specificity and regulation of NCK adaptor proteins

Principal investigatorNSERC2012Discovery Grants Program - Individual

Principal investigators: Bisson, Nicolas

$180,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Something wrong or missing on this profile? Suggest a correction

Nicolas Bisson

Research

Latest papers

Latest funding

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling.

EGFR Phosphorylates and Associates with EFNB1 to Regulate Cell Adhesion to Fibronectin.

Adapting to change: resolving the dynamic and dual roles of NCK1 and NCK2.

Integration of cancer-related genetic landscape of Eph receptors and ephrins with proteomics identifies a crosstalk between EPHB6 and EGFR.

A Multipronged Unbiased Strategy Guides the Development of an Anti-EGFR/EPHA2-Bispecific Antibody for Combination Cancer Therapy.

SRC homology 3 domains: multifaceted binding modules.

Complementary Nck1/2 Signaling in Podocytes Controls &#x3b1; Actinin-4-Mediated Actin Organization, Adhesion, and Basement Membrane Composition.

EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks.

Tyrosine phosphorylation of DEPTOR functions as a molecular switch to activate mTOR signaling.

Protein context shapes the specificity of SH3 domain-mediated interactions in vivo.

Deciphering how oncogenic tyrosine kinase receptors rewire cell signaling networks via SRC-Homology (SH) 3 domain phosphorylation

Understanding the specificity and regulation of NCK adaptor proteins

Canada Research Chairs - Tier 2

High throughput analysis of protein interactions and modifications using peptide arrays

Understanding the specificity and regulation of NCK adaptor proteins

Regulation of oncogenic receptor tyrosine kinase signalling networks by protein phosphorylation.

Canada Research Chair Tier 2

Signalisation Québec 2014

Targeted Proteomics Analysis of the Adaptor Protein Grb2 Signaling Network Dynamics in Breast Cancer.

Understanding the specificity and regulation of NCK adaptor proteins

Frequent collaborators

Patrick Laprise

Jean-Philippe Lambert

Nina Jones

Andrew Freywald

Sabine Elowe

Michel Tremblay

Anne-Claude Gingras

Jack Antel

Thomas Moss

Samuel David

Jean Charron

Humphrey Fonge

Manuel Caruso

Jasmin Lalonde

Marc-Étienne Huot

Steve Bilodeau

Complementary Nck1/2 Signaling in Podocytes Controls α Actinin-4-Mediated Actin Organization, Adhesion, and Basement Membrane Composition.