Faculty profile

Ji Zhang

ResearcherMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Ji Zhang

Researcher

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
8 publications in the last five years, latest in 2025.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 6 research grants (4 CIHR, 2 NSERC), most recently in 2023.
Supervised 1 trainee who won CIHR awards, most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

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Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Inflammation Aging Lifestyle Mouse Models Pain Behaviour Behavior Animal Model

Latest papers

Rejuvenation alleviates prolonged postsurgical pain in aging mice by mitigating inflammaging.
Pain · 2025 · senior author
The impact of nerve injury on the immune system across the lifespan is sexually dimorphic.
Neurobiology of pain (Cambridge, Mass.) · 2025 · senior author
The gut microbiota promotes pain in fibromyalgia.
Neuron · 2025

All 42 publications

Latest funding

The Role of Skin-Gut Immune Axis in Altered Pain Behaviors during Aging
CIHR · 2025 · Supervisor
$120,000
The use of cell extracts to repair injured salivary glands.
CIHR · 2023 · Co-investigator
$963,900
Exploring the potential of systemic contribution to altered pain behavior in aging mice
CIHR · 2023 · Nominated PI
$956,250

All 11 grants and awards

42 publications.

Rejuvenation alleviates prolonged postsurgical pain in aging mice by mitigating inflammaging.

Abdelkader B, Shi XQ, Zhou WBS, Castaño JD, Grant AV, Beaudry F, Zhang J

Pain2025Senior author

DOI: 10.1097/j.pain.0000000000003684 PMID: 40546103

The impact of nerve injury on the immune system across the lifespan is sexually dimorphic.

Zhou WBS, Shi XQ, Zhang AP, Millecamps M, Mogil JS, Zhang J

Neurobiology of pain (Cambridge, Mass.)2025Senior author

DOI: 10.1016/j.ynpai.2025.100195 PMID: 40978543

The gut microbiota promotes pain in fibromyalgia.

Cai W, Haddad M, Haddad R, Kesten I, Hoffman T, Laan R, Westfall S, Defaye M, Abdullah NS, Wong C, Brown N, Tansley S, Lister KC, Hooshmandi M, Wang F, Lorenzo LE, Hovhannisyan V, Ho-Tieng D, Kumar V, Sharif B, Thurairajah B, Fan J, Sahar T, Clayton C, Wu N, Zhang J, Bar-Yoseph H, Pitashny M, Krock E, Mogil JS, Prager-Khoutorsky M, Séguéla P, Altier C, King IL, De Koninck Y, Brereton NJB, Gonzalez E, Shir Y, Minerbi A, Khoutorsky A

Neuron2025

DOI: 10.1016/j.neuron.2025.03.032 PMID: 40280127

Our understanding of microglia involvement in neuropathic pain has expanded.

Sanz-Gonzalez M, Zhang J

Brain, behavior, and immunity2024Senior author

DOI: 10.1016/j.bbi.2024.02.033 PMID: 38442784

Unbiased proteomic analysis detects painful systemic inflammatory profile in the serum of nerve-injured mice.

Zhou WBS, Shi XQ, Liu Y, Tran SD, Beaudry F, Zhang J

Pain2023Senior author

DOI: 10.1097/j.pain.0000000000002695 PMID: 35587992

Potentiation of morphine antinociception and inhibition of diabetic neuropathic pain by the multi-chemokine receptor antagonist peptide RAP-103.

Ruff MR, Inan S, Shi XQ, Meissler JJ, Adler MW, Eisenstein TK, Zhang J

Life sciences2022Senior author

DOI: 10.1016/j.lfs.2022.120788 PMID: 35817166

Microglia-mediated degradation of perineuronal nets promotes pain.

Tansley S, Gu N, Guzmán AU, Cai W, Wong C, Lister KC, Muñoz-Pino E, Yousefpour N, Roome RB, Heal J, Wu N, Castonguay A, Lean G, Muir EM, Kania A, Prager-Khoutorsky M, Zhang J, Gkogkas CG, Fawcett JW, Diatchenko L, Ribeiro-da-Silva A, De Koninck Y, Mogil JS, Khoutorsky A

Science (New York, N.Y.)2022

DOI: 10.1126/science.abl6773 PMID: 35617374

Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain.

Tansley S, Uttam S, Ureña Guzmán A, Yaqubi M, Pacis A, Parisien M, Deamond H, Wong C, Rabau O, Brown N, Haglund L, Ouellet J, Santaguida C, Ribeiro-da-Silva A, Tahmasebi S, Prager-Khoutorsky M, Ragoussis J, Zhang J, Salter MW, Diatchenko L, Healy LM, Mogil JS, Khoutorsky A

Nature communications2022

DOI: 10.1038/s41467-022-28473-8 PMID: 35149686

Does Low Grade Systemic Inflammation Have a Role in Chronic Pain?

Zhou WBS, Meng J, Zhang J

Frontiers in molecular neuroscience2021Senior author

DOI: 10.3389/fnmol.2021.785214 PMID: 34858140

Corrigendum: CX3CR1 But Not CCR2 Expression Is Required for the Development of Autoimmune Peripheral Neuropathy in Mice.

Oladiran O, Shi XQ, Fournier S, Zhang J

Frontiers in immunology2021Senior author

DOI: 10.3389/fimmu.2021.765892 PMID: 34630439

The Role of Skin-Gut Immune Axis in Altered Pain Behaviors during Aging

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Guo, Yu

Keywords: Aging; Inflammation; Microbiome; Pain

$120,000

The use of cell extracts to repair injured salivary glands.

Co-investigatorCIHR2023Project Grant

Principal investigators: Tran, Simon D

Keywords: Cell Extract; Dental Diseases; Dry Mouth; Molecular Therapy; Oral Biology; Oral Cancer; Regenerative Medicine; Saliva; Salivary Gland; Salivary Hypofunction

$963,900

Exploring the potential of systemic contribution to altered pain behavior in aging mice

Nominated PICIHR2023Project Grant

Principal investigators: Zhang, Ji

Keywords: Aging; Behaviour; Inflammation; Lifestyle; Mouse Models; Pain

$956,250

Exploring the potential of systemic contribution to altered pain behavior in aging mice

Nominated PICIHR2022Project Grant

Principal investigators: Zhang, Ji

Keywords: Aging; Behavior; Inflammation; Lifestyle; Mouse Models; Pain

$100,000

Dietary modulation of macrophage identity: potential impact on nociceptive sensory response

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Zhang, Ji

$192,000

Tackling CD8+ T cells and macrophages in autoimmune peripheral neuropathy

Nominated PICIHR2017Project Grant

Principal investigators: Zhang, Ji

Keywords: Animal Model; Autoimmune Response; Cd8 T Cells; Demyelination; Flow Cytometry; Inflammation; Macrophages; Molecular And Cellular Mechanisms; Peripheral Neuropathy; Viral Infection

$852,975

Individual Differences in Pain Sensitivity: Genetic and Environmental Factors in Mice and Humans

Co-investigatorCIHR2016Foundation Grant

Principal investigators: Mogil, Jeffrey S

Keywords: Algesiometry; Genetics; Pain; Sex Differences; Social Modulation; Translation

$1,346,653

Sex differences in spinal immune system involvement in chronic pain

Co-investigatorCIHR2012Operating Grant

Principal investigators: Mogil, Jeffrey S

Keywords: Behaviour; Cytokines; Immune System; Immunohistochemistry; Microglia; Pain; Pharmacology; Sex Differences; T Cells; Trangenics

$636,906

To understand aging dependent microglial degeneration: impacts on neuronal function

Principal investigatorNSERC2011Discovery Grants Program - Individual

Principal investigators: Zhang, Ji

$145,000

Neuron-Microglia-Astrocyte interaction in the pathogenesis of neuropathic pain

Nominated PICIHR2010Operating Grant

Principal investigators: Zhang, Ji

Keywords: Anatomical Studies; Behavioral Studies; Glial Cells; Immune Response; Pain

$641,070

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Ji Zhang

Research

Latest papers

Latest funding

Rejuvenation alleviates prolonged postsurgical pain in aging mice by mitigating inflammaging.

The impact of nerve injury on the immune system across the lifespan is sexually dimorphic.

The gut microbiota promotes pain in fibromyalgia.

Our understanding of microglia involvement in neuropathic pain has expanded.

Unbiased proteomic analysis detects painful systemic inflammatory profile in the serum of nerve-injured mice.

Potentiation of morphine antinociception and inhibition of diabetic neuropathic pain by the multi-chemokine receptor antagonist peptide RAP-103.

Microglia-mediated degradation of perineuronal nets promotes pain.

Single-cell RNA sequencing reveals time- and sex-specific responses of mouse spinal cord microglia to peripheral nerve injury and links ApoE to chronic pain.

Does Low Grade Systemic Inflammation Have a Role in Chronic Pain?

Corrigendum: CX3CR1 But Not CCR2 Expression Is Required for the Development of Autoimmune Peripheral Neuropathy in Mice.

Dietary modulation of macrophage identity: potential impact on nociceptive sensory response

To understand aging dependent microglial degeneration: impacts on neuronal function

Frequent collaborators

Yves De Koninck

Yves De Koninck

Arkady Khoutorsky

Alfredo Ribeiro-Da-Silva

Luda Diatchenko

Masha Prager-Khoutorsky

Serge Rivest

Serge Rivest

Samuel David

Jean Ouellet

Emerson Krock

Feng Wang

Amira Klip

Artur Kania

Tomoko Takano

Giamal Luheshi

Christophe Altier

Lisbet Haglund