Faculty profile

Simon Gravel

ResearcherHuman GeneticsMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Simon Gravel

Researcher

Human Genetics

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
22 publications in the last five years, latest in 2026.
Senior (last) author on 5 recent papers, a sign of leading a research group.
Principal investigator on 7 research grants (5 CIHR, 2 NSERC), most recently in 2024.
Supervisor on 2 trainee awards (2 CIHR), most recently in 2016.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Crc Population Genetics Algorithms Data Compression Data Sharing Imputation Statistical Genetics Admixture

Latest papers

ATM c.7374_7375insAlu is a French-Canadian founder pathogenic variant associated with predisposition to pancreatic and breast cancer.
Journal of medical genetics · 2026
Inferring hominin history with recurrent gene flow from single unphased genomes and a two-locus statistic.
bioRxiv : the preprint server for biology · 2026
A comprehensive genomic framework for identifying genes predisposing to homologous recombination repair-deficient breast or ovarian cancer.
BJC reports · 2026

All 52 publications

Latest funding

Canada Research Chair - Tier 1
CIHR · 2024 · Nominated PI
$1,400,000
Evolutionary models using linkage disequilibrium
NSERC · 2023 · Principal investigator
$60,000
Quantitative approaches to increase the power and equity of genetic research
CIHR · 2020 · Nominated PI
$378,675

All 10 grants and awards

52 publications.

ATM c.7374_7375insAlu is a French-Canadian founder pathogenic variant associated with predisposition to pancreatic and breast cancer.

Wang Y, Domecq C, Cuggia A, Mejia-Garcia A, Romero JM, Hamel N, Lapointe R, Provencher D, Mes-Masson AM, Tonin PN, Gravel S, Zogopoulos G, Foulkes WD

Journal of medical genetics2026

DOI: 10.1136/jmg-2025-111441 PMID: 41916721

Inferring hominin history with recurrent gene flow from single unphased genomes and a two-locus statistic.

Collier NW, Gravel S, Ragsdale AP

bioRxiv : the preprint server for biology2026

DOI: 10.64898/2026.04.11.717825 PMID: 41993441

A comprehensive genomic framework for identifying genes predisposing to homologous recombination repair-deficient breast or ovarian cancer.

Camacho-Valenzuela J, Matis T, Roca C, Cuamatzi Flores JL, Hamel N, Rivera B, Gravel S, Polak P, Robles-Espinoza CD, Foulkes WD

BJC reports2026

DOI: 10.1038/s44276-026-00218-w PMID: 41951763

Whole-genome sequencing of 3135 individuals representing the genetic diversity of the Japanese population.

Higasa K, Kamatani Y, Kawaguchi T, Kawaguchi S, Sakaue S, Yang TY, Okada Y, Momozawa Y, Yamaguchi I, Nelson D, Gravel S, Murakami Y, Yamada R, Matsuo K, Yamano Y, Kim C, Seo JS, Kubo M, Matsuda F

Journal of human genetics2026

DOI: 10.1038/s10038-025-01430-1 PMID: 41206389

Topological stratification of continuous genetic variation in large biobanks.

Diaz-Papkovich A, Zabad S, Snell H, Ben-Eghan C, Anderson-Trocmé L, Femerling G, Nathan V, Patel J, Gravel S

PLoS genetics2026Senior author

DOI: 10.1371/journal.pgen.1012068 PMID: 41838785

A multi-ancestry genetic reference for the Quebec population.

McClelland P, Femerling G, Laflamme R, Mejia-Garcia A, Sayahian Dehkordi M, Xiao H, Diaz-Papkovich A, Pelletier J, Grenier JC, Lo KS, Anderson-Trocmé L, Bellavance J, Chapdelaine V, Gagnon G, De Mori A, Martinez G, Mohler K, de Malliard T, Labbé C, Labrecque M, Montpetit A, Spiegelman D, Rouleau GA, Théroux JF, Zhou H, Girard SL, Hussin JG, Laberge AM, Bhérer C, Tetreault M, Gagliano Taliun SA, Taliun D, Gravel S, Lettre G

Nature communications2026

DOI: 10.1038/s41467-026-68820-7 PMID: 41634041

Using the ancestral recombination graph to study the history of rare variants in founder populations.

Mejia-Garcia A, Diaz-Papkovich A, Sillon G, D'Agostino D, Chong AL, Chong G, Lo KS, Baret L, Hamel N, Chapdelaine V, Foulkes WD, Taliun D, Shapiro AJ, Lettre G, Gravel S

American journal of human genetics2025Senior author

DOI: 10.1016/j.ajhg.2025.10.005 PMID: 41172993

PMS2 c.2117del (p.Lys706Serfs*19) is the Most Frequent Cancer-Associated Founder Pathogenic Variant in the French-Canadian Population of Quebec, Canada.

Chong AL, Mejia-Garcia A, Behl S, El Haffaf Z, Chénier S, Maranda B, Désilets V, Lévesque S, Castonguay L, Mes-Masson AM, Giroux S, Rousseau F, Hamel N, Chong G, Gravel S, Foulkes WD

Clinical genetics2025

DOI: 10.1111/cge.14784 PMID: 40546006

Sparse polygenic risk score inference with the spike-and-slab LASSO.

Song J, Zabad S, Yang A, Gravel S, Li Y

Bioinformatics (Oxford, England)2025

DOI: 10.1093/bioinformatics/btaf578 PMID: 41105181

The Indian Ocean slave trade and colonial expansion resulted in strong sex-biased admixture in South Africa.

Reynolds AW, Schurz H, Meeks G, Gravel S, Myrick JW, Edington S, Mendez FL, Werely CJ, van Helden PD, Hoal EG, Poznik GD, Kim M, Uren C, Underhill PA, Möller M, Henn BM

American journal of human genetics2025

DOI: 10.1016/j.ajhg.2025.08.012 PMID: 40992378

Canada Research Chair - Tier 1

Nominated PICIHR2024Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: Gravel, Simon

Keywords: Crc

$1,400,000

Evolutionary models using linkage disequilibrium

Principal investigatorNSERC2023Discovery Grants Program - Individual

Principal investigators: Gravel, Simon

Keywords: Computational biology; Demography; Genetic Drift; Linkage disequilibrium; Natural selection; Partial Differential Equations; Population Genetics; Statistical Genetics; Symmetries

$60,000

Quantitative approaches to increase the power and equity of genetic research

Nominated PICIHR2020Project Grant

Principal investigators: Gravel, Simon

Keywords: Algorithms; Data Compression; Data Sharing; Imputation; Population Genetics; Statistical Genetics

$378,675

Investigating the role of non-coding variations in epilepsy

Co-investigatorCIHR2019Project Grant

Principal investigators: Girard, Simon

Keywords: Epilepsy; Genealogy; Genomics; Identity-By-Descent; Non Coding Variants; Strs; Structural Variants

$436,050

Evolutionary genetics in extended populations

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Gravel, Simon

$168,000

Canada Research Chair - Tier 2 - CIHR Funded

Nominated PICIHR2017Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Gravel, Simon

Keywords: Crc

$500,000

The Impact of Tumor Growth Dynamics on Heterogeneity, Sampling Bias and Metastasis Diversity

SupervisorCIHR2016Undergraduate: Genetics - ICS

Principal investigators: Ahmed, Zafarali

Keywords: Ics Studentship

$5,000

Investigating and Modelling Metastasis due to Circulating Tumor Cell Clusters

SupervisorCIHR2015Undergraduate: Summer Studentship Award - Institute Community Support

Principal investigators: Ahmed, Zafarali

Keywords: Ics Studentship

$5,000

Modelling recent genetic events in complex cohorts

Nominated PICIHR2014Operating Grant

Principal investigators: Gravel, Simon

Keywords: Admixture; Association Study; Coalescent Theory; Gene Flow; Gwas; Identity-By-Descent; Pedigree; Population Genetics; Psmc

$289,886

CANADA RESEARCH CHAIRHOLDER - Tier 2 / TITULAIRE DE CHAIRE DE RECHERCHE DU CANADA - Niveau 2

Nominated PICIHR2013Canada Research Chairs - CIHR Funded - Tier 2

Principal investigators: Gravel, Simon

Keywords: Crc

$500,000

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Simon Gravel

Research

Latest papers

Latest funding

ATM c.7374_7375insAlu is a French-Canadian founder pathogenic variant associated with predisposition to pancreatic and breast cancer.

Inferring hominin history with recurrent gene flow from single unphased genomes and a two-locus statistic.

A comprehensive genomic framework for identifying genes predisposing to homologous recombination repair-deficient breast or ovarian cancer.

Whole-genome sequencing of 3135 individuals representing the genetic diversity of the Japanese population.

Topological stratification of continuous genetic variation in large biobanks.

A multi-ancestry genetic reference for the Quebec population.

Using the ancestral recombination graph to study the history of rare variants in founder populations.

PMS2 c.2117del (p.Lys706Serfs*19) is the Most Frequent Cancer-Associated Founder Pathogenic Variant in the French-Canadian Population of Quebec, Canada.

Sparse polygenic risk score inference with the spike-and-slab LASSO.

The Indian Ocean slave trade and colonial expansion resulted in strong sex-biased admixture in South Africa.

Evolutionary models using linkage disequilibrium

Evolutionary genetics in extended populations

Frequent collaborators

Yue Li

Anne-Marie Mes-Masson

Daniel Taliun

Daniel Taliun

Guillaume Lettre

Mikko Taipale

Daniel Schramek

Jacek Majewski

Frank Sicheri

Nada Jabado

Anne-Marie Laberge

Réjean Lapointe

Luigi Bouchard

Luda Diatchenko

Kevin Petrecca

Sarkis Meterissian

Catalin Mihalcioiu

Jean-Yves Masson

Luigi Bouchard

Guy Rouleau

Kevin Petrecca