Faculty profile

Daniel Schramek

ResearcherLunenfeld-Tanenbaum Research InstituteUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.

Daniel Schramek

Researcher

Lunenfeld-Tanenbaum Research Institute

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
32 publications in the last five years, latest in 2026.
Senior (last) author on 10 recent papers, a sign of leading a research group.
Principal investigator on 13 research grants (12 CIHR, 1 NSERC), most recently in 2025.
Supervisor on 7 trainee awards (7 CIHR), most recently in 2024.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

184

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

Profiles and links

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Signals and details

Research

Lung Cancer In Vivo Crispr Screening Cancer Research Functional Genomics Copy Number Alterations Kras Laser Capture Microdissection Mass Spectrometry

Latest papers

The legacy of a gentleman scientist: Pierre Hainaut
Cell Death and Differentiation · 2026 · senior author
Temporal control of sgRNA library activation unlocks large-scale in vivo CRISPR screens.
Cell reports methods · 2026
[18F]FDG PET/CT multiomics identifies Hedgehog-driven HPV-negative head and neck squamous cell carcinoma.
Molecular cancer · 2026

All 54 publications

Latest funding

Genomic drivers of therapy resistant pancreatic cancer microenvironments
CIHR · 2026 · Co-investigator
$1,273,726
Advancing lung cancer biology through integrated spatial proteomics and in vivo CRISPR screening
CIHR · 2025 · Principal investigator
$1,415,252
Advancing lung cancer biology through integrated spatial proteomics and in vivo CRISPR screening
CIHR · 2025 · Principal investigator
$100,000

All 25 grants and awards

54 publications.

The legacy of a gentleman scientist: Pierre Hainaut

Arnoult C, Attardi LD, Batsheva K, Blandino G, Burns KH, Del Sal G, Kirsch DG, Lane DP, Levine AJ, Lozano G

Cell Death and Differentiation2026Senior author

DOI: 10.1038/s41418-025-01586-5

Temporal control of sgRNA library activation unlocks large-scale in vivo CRISPR screens.

Fenoglio S, Yu Y, Tepper J, Grove L, Bejnood A, Meier SR, Choi AH, Wu HJ, Devault A, Liu S, Shen B, Khendu T, Stowe H, Uijttewaal ECH, Zhang M, Haines BB, Wilker E, Huang A, Schramek D, Elling U, Pan X, Andersen JN, Teng T

Cell reports methods2026

DOI: 10.1016/j.crmeth.2026.101470 PMID: 42225068

[18F]FDG PET/CT multiomics identifies Hedgehog-driven HPV-negative head and neck squamous cell carcinoma.

Stoiber S, Pölöske D, Spielvogel CP, Gurnhofer E, Schlederer M, Haberl D, Philippe C, Elmer DP, Morrigl R, Neubauer HA, Bystrý V, Trachtová K, Verswyvel H, Zaryouh H, Lin A, Deben C, Heiduschka G, Dahlhoff M, Aberger F, Schramek D, Hacker M, Haug AR, Kenner L

Molecular cancer2026

DOI: 10.1186/s12943-026-02607-8 PMID: 41904511

Epigenetic maintenance of the injury response state in glioblastoma stem cells.

Molaei F, MacLeod G, Haider S, Tiffany A, Oteng FM, Berman JM, Skirzynska A, Shoichet MS, Schramek D, Dirks PB, Angers S

Neuro-oncology advances2026

DOI: 10.1093/noajnl/vdag002 PMID: 41756760

Systematic discovery of pathogen effector functions across human pathogens and pathways.

Pachano T, Leng H, Dugied G, Tribble T, Loubiere V, Lee Y, Rauh F, Manon V, Yuan K, Nurtanto J, Schleiffer A, Young V, Weller B, Lyons EA, Hass MR, Kottyan LC, Weirauch MT, Fuxman Bass JI, Newton HJ, Ensminger AW, Falter-Braun P, Chen J, Schramek D, Stark A, Taipale M

Cell2026

DOI: 10.1016/j.cell.2026.06.017 PMID: 42379168

Aneuploidy selects for the acquisition of driver genes in breast cancer.

Al-Zahrani KN, Langille ER, Nurtanto J, Obersterescu A, Teng K, Lowden C, Dessapt J, Chiu CH, Caldwell LV, Cook DP, Pérez-Castro MA, Berman JM, Tsai R, Bahcheli AT, Mbamalu G, Wu S, Narimatsu M, Lopes AG, Fotiadou I, Chan K, Zhang L, Bang KWA, Parsons MJ, Mourao L, Temel EI, McCulla L, Sravya P, Zhang L, Sajjakulnukit P, Lyssiotis CA, Borowsky AD, Scheele CLGJ, Wahl DR, Jackson HW, Stewart KS, Fuchs E, Egan SE, Pujana MA, Reimand J, Wrana JL, Schramek D

Nature2026Senior author

DOI: 10.1038/s41586-026-10752-9 PMID: 42420452

Switching Drivers: Epigenetic Rewiring to Genetic Progression in Glioma.

Drucker KL, Jenkins RB, Schramek D

Cancer research2025Senior author

DOI: 10.1158/0008-5472.can-24-4907 PMID: 39786420

TRIM28-dependent developmental heterogeneity determines cancer susceptibility through distinct epigenetic states.

Panzeri I, Fagnocchi L, Apostle S, Tompkins M, Wolfrum E, Madaj Z, Hostetter G, Liu Y, Schaefer K, Yang CH, Bergsma A, Drougard A, Dror E, PERMUTE, Chandler DP, Schramek D, Triche TJ, Pospisilik JA

Nature cancer2025

DOI: 10.1038/s43018-024-00900-3 PMID: 39856421

Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes.

Uusküla-Reimand L, Lee CA, Oh RH, Klein ZP, Adler N, Akhtar Alvi S, Langille E, Pasini E, Cheng KCL, Serafimova E, Abd-Rabbo D, Hou H, Tsai R, Bhat M, Schramek D, Wilson MD, Reimand J

Nature communications2025

DOI: 10.1038/s41467-025-65005-6 PMID: 41271620

Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways.

Pachano T, Leng H, Dugied G, Tribble T, Loubiere V, Rauh F, Lee Y, Schleiffer A, Young V, Weller B, Lyons EA, Hass MR, Kottayan LC, Weirauch MT, Fuxman Bass JI, Newton HJ, Ensminger AW, Braun PF, Schramek D, Stark A, Taipale M

bioRxiv : the preprint server for biology2025

DOI: 10.1101/2025.11.17.687821 PMID: 41332698

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Daniel Schramek

Research

Latest papers

Latest funding

The legacy of a gentleman scientist: Pierre Hainaut

Temporal control of sgRNA library activation unlocks large-scale in vivo CRISPR screens.

[18F]FDG PET/CT multiomics identifies Hedgehog-driven HPV-negative head and neck squamous cell carcinoma.

Epigenetic maintenance of the injury response state in glioblastoma stem cells.

Systematic discovery of pathogen effector functions across human pathogens and pathways.

Aneuploidy selects for the acquisition of driver genes in breast cancer.

Switching Drivers: Epigenetic Rewiring to Genetic Progression in Glioma.

TRIM28-dependent developmental heterogeneity determines cancer susceptibility through distinct epigenetic states.

Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes.

Systematic Discovery of Pathogen Effector Functions across Human Pathogens and Pathways.

Frequent collaborators

Mikko Taipale

Ellen Langille

Rod Bremner

Stephane Angers

Nada Jabado

Anne-Claude Gingras

Mathieu Lupien

Jeffrey Wrana

Kieran Campbell

Yeojin Lee

Cynthia Guidos

Livia Garzia

Vuk Stambolic

Simon Gravel

Timothy Whelan

Razqallah Hakem

Rama Khokha

Li Zhang

Jacek Majewski

Frank Sicheri

Ming-Sound Tsao

Alex Gregorieff

Tae-Hee Kim

Vijay Ramaswamy

Ivan Topisirovic

Mamatha Bhat

Shane Harding

Alejandro Berlin

Lily Zhou

Ivan Topisirovic

Steven Gallinger

Jean-Philippe Julien

Xi Huang

Samuel Weiss

Sylvain Meloche

Sheila Singh

Jason Moffat

Giovanni Blandino

Thomas Kislinger

Stefan Hofer