Faculty profile

Nathalie Labrecque

ResearcherMedicineUniversité de Montréal

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université de Montréal directory, so their courses may be missing. Find their university profile.

Nathalie Labrecque

Researcher

Medicine

Health Sciences

Université de Montréal

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
6 publications in the last five years, latest in 2025.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 14 research grants (9 CIHR, 5 NSERC), most recently in 2025.
Supervised 1 trainee who won CIHR awards, most recently in 2010.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

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Signals and details

Research

Immunology Immunotherapy T Cell Differentiation Effector T Cells Notch Signalling Cd8+ T Lymphocytes Infection Cytokines

Latest papers

Blockade of colon cancer metastasis via single and double silencing of PCSK7/PCSK9: enhanced T cells cytotoxicity in mouse and human.
Journal for immunotherapy of cancer · 2025
Early Notch signals from fibroblastic reticular cells program effector CD8+ T cell differentiation.
The Journal of experimental medicine · 2025 · senior author
Watch your clock: it matters for immunotherapy.
Trends in cancer · 2024 · senior author

All 41 publications

Latest funding

Role of the NR4A and bZIP transcription factor families during CD8+ T cell response
CIHR · 2025 · Nominated PI
$1,204,875
The transcriptional and epigenomic mechanisms underlying the circadian regulation of CD8 T cell response
CIHR · 2022 · Co-investigator
$1,243,125
IMAGE-GUIDED INJECTION WITH A HIGH-RESOLUTION ULTRASOUND SYSTEM ADAPTED FOR RODENT USE
NSERC · 2022 · Co-investigator
$146,541

All 21 grants and awards

41 publications.

Blockade of colon cancer metastasis via single and double silencing of PCSK7/PCSK9: enhanced T cells cytotoxicity in mouse and human.

Porcheron C, Le Devehat M, Roubtsova A, Bayat H, Evagelidis A, Jafarzadeh L, Sachan V, Labrecque N, Fonta Holder A, Susan-Resiga D, Essalmani R, Boudreau G, Prat A, Cusseddu R, Côté JF, Khatib AM, Delisle JS, Seidah NG

Journal for immunotherapy of cancer2025

DOI: 10.1136/jitc-2024-011364 PMID: 40518289

Early Notch signals from fibroblastic reticular cells program effector CD8+ T cell differentiation.

Maurice De Sousa D, Perkey E, Le Corre L, Boulet S, Gómez Atria D, Allman A, Duval F, Daudelin JF, Brandstadter JD, Lederer K, Mezrag S, Odagiu L, Ennajimi M, Sarrias M, Decaluwe H, Koch U, Radtke F, Ludewig B, Siebel CW, Maillard I, Labrecque N

The Journal of experimental medicine2025Senior author

DOI: 10.1084/jem.20231758 PMID: 40111253

Watch your clock: it matters for immunotherapy.

Cermakian N, Labrecque N

Trends in cancer2024Senior author

DOI: 10.1016/j.trecan.2024.06.004 PMID: 38942640

Regulation of Cytotoxic CD8+ T Cells by the Circadian Clock.

Cermakian N, Labrecque N

Journal of immunology (Baltimore, Md. : 1950)2023Senior author

DOI: 10.4049/jimmunol.2200516 PMID: 36542828

Circadian rhythms in adaptive immunity and vaccination.

Cermakian N, Stegeman SK, Tekade K, Labrecque N

Seminars in immunopathology2022Senior author

DOI: 10.1007/s00281-021-00903-7 PMID: 34825270

The Idd2 Locus Confers Prominent Resistance to Autoimmune Diabetes.

Lombard-Vadnais F, Collin R, Daudelin JF, Chabot-Roy G, Labrecque N, Lesage S

Journal of immunology (Baltimore, Md. : 1950)2022

DOI: 10.4049/jimmunol.2100456 PMID: 35039332

The Assessment of Circadian Rhythms Within the Immune System.

Nobis CC, Cuesta M, Daudelin JF, Dubeau Laramée G, Boivin DB, Labrecque N, Cermakian N

Methods in molecular biology (Clifton, N.J.)2021

DOI: 10.1007/978-1-0716-0381-9_3 PMID: 33284434

NR4A3 Mediates Thymic Negative Selection.

Boulet S, Odagiu L, Dong M, Lebel MÈ, Daudelin JF, Melichar HJ, Labrecque N

Journal of immunology (Baltimore, Md. : 1950)2021Senior author

DOI: 10.4049/jimmunol.1901228 PMID: 34312259

p16INK4a Regulates Cellular Senescence in PD-1-Expressing Human T Cells.

Janelle V, Neault M, Lebel MÈ, De Sousa DM, Boulet S, Durrieu L, Carli C, Muzac C, Lemieux S, Labrecque N, Melichar HJ, Mallette FA, Delisle JS

Frontiers in immunology2021

DOI: 10.3389/fimmu.2021.698565 PMID: 34434190

Role of the Orphan Nuclear Receptor NR4A Family in T-Cell Biology.

Odagiu L, May J, Boulet S, Baldwin TA, Labrecque N

Frontiers in endocrinology2020Senior author

DOI: 10.3389/fendo.2020.624122 PMID: 33597928

Role of the NR4A and bZIP transcription factor families during CD8+ T cell response

Nominated PICIHR2025Project Grant

Principal investigators: Labrecque, Nathalie

Keywords: Cytotoxic T Lymphocytes; Immunology; Immunotherapy; T Cell Differentiation; T Lymphocytes; Transcription Factors

$1,204,875

The transcriptional and epigenomic mechanisms underlying the circadian regulation of CD8 T cell response

Co-investigatorCIHR2022Project Grant

Principal investigators: Cermakian, Nicolas

Keywords: Cell Signalling; Chromatin; Circadian Clock; Circadian Rhythms; Gene Expression; Genomics; Mouse Model; T Lymphocyte; Transcription Factor; Vaccination

$1,243,125

IMAGE-GUIDED INJECTION WITH A HIGH-RESOLUTION ULTRASOUND SYSTEM ADAPTED FOR RODENT USE

Co-investigatorNSERC2022Research Tools and Instruments

Principal investigators: Lesage, Sylvie

$146,541

Plan d'action pour la gestion de la douleur chronique du Ministère de la Santé et des Services sociaux du Québec: Évaluation de la mise en œuvre et des impacts des projets initiaux en vue d'une généralisation progressive à l'ensemble du Québec

Principal investigatorCIHR2022Team Grant: THINC Implem. Science - Care of Patients Covered in IMHA mandate

Principal investigators: Choinière, Manon; Labrecque, Nathalie; Boulanger, Aline; Couturier, Yves; Page, Gabrielle; Vedel, Isabelle

Keywords: Accessibilité Aux Services De Santé; Douleur Chronique; Mobilisation Des Connaissances; Science De La Mise En Oeuvre; Services Et Politiques De Santé; Soins Primaires; Système De Santé Apprenant

$785,627

The Notch signaling pathway: a master regulator of CD8+ T cell differentiation

Nominated PICIHR2021Project Grant

Principal investigators: Labrecque, Nathalie

Keywords: Cd8 T Lymphocytes; Cytokines; Effector T Cells; Exhausted T Cells; Immunological Memory; Immunology; Immunotherapy; Infection; Notch Signalling; T Cell Differentiation

$1,013,625

The role of UCH family deubiquitinases in T cell biology

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: Labrecque, Nathalie

$252,000

Regulation of CD8+ T cell responses by the nuclear orphan receptor NR4A3

Nominated PICIHR2019Project Grant

Principal investigators: Labrecque, Nathalie

Keywords: Cd8+ T Lymphocytes; Cytokines; Effector T Cells; Immunological Memory; Immunology; Immunotherapy; Orphan Nuclear Receptors; T Cell Differentiation

$952,425

A Benchtop Cell Sorter for Accelerating the Discovery of Physiopathological Processes

Co-investigatorNSERC2017Research Tools and Instruments

Principal investigators: Milot, ERIC

$146,629

The Notch signalling pathway: a master regulator of CD8+ T cell differentiation

Nominated PICIHR2016Project Grant

Principal investigators: Labrecque, Nathalie

Keywords: Cd8+ T Lymphocytes; Chronic Infection; Effector T Cells; Immunology; Immunotherapy; Memory T Cells; Notch Signalling; T Cell Differentiation; Transcriptional Control; Vaccination

$100,000

The Notch signalling pathway: a master regulator of CD8+ T cell differentiation

Nominated PICIHR2016Project Grant

Principal investigators: Labrecque, Nathalie

Keywords: Cd8+ T Lymphocytes; Chronic Infection; Effector T Cells; Immunology; Immunotherapy; Memory T Cells; Notch Signalling; T Cell Differentiation; Transcriptional Control; Vaccine

$837,190

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Nathalie Labrecque

Research

Latest papers

Latest funding

Blockade of colon cancer metastasis via single and double silencing of PCSK7/PCSK9: enhanced T cells cytotoxicity in mouse and human.

Early Notch signals from fibroblastic reticular cells program effector CD8+ T cell differentiation.

Watch your clock: it matters for immunotherapy.

Regulation of Cytotoxic CD8+ T Cells by the Circadian Clock.

Circadian rhythms in adaptive immunity and vaccination.

The Idd2 Locus Confers Prominent Resistance to Autoimmune Diabetes.

The Assessment of Circadian Rhythms Within the Immune System.

NR4A3 Mediates Thymic Negative Selection.

p16INK4a Regulates Cellular Senescence in PD-1-Expressing Human T Cells.

Role of the Orphan Nuclear Receptor NR4A Family in T-Cell Biology.

Role of the NR4A and bZIP transcription factor families during CD8+ T cell response

The transcriptional and epigenomic mechanisms underlying the circadian regulation of CD8 T cell response

IMAGE-GUIDED INJECTION WITH A HIGH-RESOLUTION ULTRASOUND SYSTEM ADAPTED FOR RODENT USE

Plan d'action pour la gestion de la douleur chronique du Ministère de la Santé et des Services sociaux du Québec: Évaluation de la mise en œuvre et des impacts des projets initiaux en vue d'une généralisation progressive à l'ensemble du Québec

The Notch signaling pathway: a master regulator of CD8+ T cell differentiation

The role of UCH family deubiquitinases in T cell biology

Regulation of CD8+ T cell responses by the nuclear orphan receptor NR4A3

A Benchtop Cell Sorter for Accelerating the Discovery of Physiopathological Processes

The Notch signalling pathway: a master regulator of CD8+ T cell differentiation

The Notch signalling pathway: a master regulator of CD8+ T cell differentiation

Frequent collaborators

Nicolas Cermakian

Sylvain Meloche

Przemyslaw Sapieha

Przemyslaw Sapieha

Sylvie Lesage

Moutih Rafei

Annik Prat

Moutih Rafei

Kai-Florian Storch

Malika Oubaha

Martin Olivier

Claude Perreault

CHEOLHO Cheong

Michel Meunier

Alain Lamarre

Martin Pelletier

Fawzi Aoudjit

Guillaume Lettre

Jean-Sébastien Joyal

Mathieu Laplante