Faculty profile

Michael Overduin

ResearcherBiochemistryUniversity of Alberta

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Alberta directory, so their courses may be missing. Find their university profile.

Michael Overduin

Researcher

Biochemistry

Natural Sciences

University of Alberta

Edmonton, Alberta, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
21 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 5 research grants (5 NSERC), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

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Publications

Citations

Collaborators

Grants

Publications by year

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Signals and details

Research

affinity tags copolymer synthesis drug delivery drug discovery fluorescent polymer membrane proteins nanodiscs nanotechnology

Latest papers

Membrane Models and the Pursuit of Coherence.
Biochemistry · 2026
Nucleotide-dependent domain interactions of Aha1-type co-chaperones with Hsp90 reveal evolutionarily conserved binding determinants.
Cell stress & chaperones · 2026
Proteomic Snapshots of Structural Cross-Linking Rearrangements in Ca2+/Calmodulin-Dependent Kinase-1-Delta Associated with Its Regulation by ATP, Ca2+/Calmodulin, and Reduction Potential.
Journal of proteome research · 2026

All 54 publications

Latest funding

Exploitation of Lipid Codons for Pharmaceutical and Biotech Industry Growth
NSERC · 2025 · Principal investigator
$100,000
Extension of the Biological Code through the Proteolipid Code
NSERC · 2024 · Principal investigator
$63,000
Functional Derivatives of Maleic Acid copolymers and Native Nanodisc Technology (FUNDEMANNT) [Phase 1]
NSERC · 2020 · Principal investigator
$185,000

All 5 grants and awards

54 publications.

Membrane Models and the Pursuit of Coherence.

Kervin TA, Zhang Z, Clark M, Overduin M, Zhang P

Biochemistry2026

DOI: 10.1021/acs.biochem.6c00367 PMID: 42482338

Nucleotide-dependent domain interactions of Aha1-type co-chaperones with Hsp90 reveal evolutionarily conserved binding determinants.

Amoah DP, Bhat R, Trad M, Hussein SK, Overduin M, LaPointe P

Cell stress & chaperones2026

DOI: 10.1016/j.cstres.2026.100179 PMID: 42025871

Proteomic Snapshots of Structural Cross-Linking Rearrangements in Ca2+/Calmodulin-Dependent Kinase-1-Delta Associated with Its Regulation by ATP, Ca2+/Calmodulin, and Reduction Potential.

Mbabala L, Tshililo NO, Vlok M, Vendrell I, Fischer R, Tabb DL, Trieber CA, Adra TRC, Overduin M, Butterworth S, Kenyon CP

Journal of proteome research2026

DOI: 10.1021/acs.jproteome.5c00981 PMID: 41837851

Structural insights into the binding modes of SHP2 allosteric inhibitors.

Jama M, Mosa FES, Overduin M, Barakat KH

In silico pharmacology2026

DOI: 10.1007/s40203-025-00551-x PMID: 41613633

Design of zwitterionic fluorescent polymers for membrane protein solubilization into native nanodiscs

Overduin M, Kuyler GC, Esmaili M, Trieber CA, Acevedo-Morantes C, Orazietti AP, Shaykhutdinov R, Bhat RK, Omotoso T, Tajammul S

Biophysical Chemistry20256 citationsFirst author

DOI: 10.1016/j.bpc.2025.107489

The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts.

Chen J, Yap MC, Bassot A, Pascual DM, Makio T, Zimmermann J, Mast H, Bhat R, Fleury SG, Fan Y, Buzatto AZ, Moore J, Ballanyi K, Li L, Overduin M, Lemieux MJ, Lemieux H, Mancini GMS, Morgan B, Marcogliese PC, Simmen T

Cell reports2025

DOI: 10.1016/j.celrep.2025.116486 PMID: 41175374

Molecular mechanisms associated with the interaction of external electromagnetic fields in protein dynamics and aggregation: a focus on amyloid-βpeptide.

Alejandro MM, Herlinda BJ, Aparicio-Bautista DI, Siddhartha MR, Overduin M, Basurto-Islas G

Progress in biomedical engineering (Bristol, England)2025

DOI: 10.1088/2516-1091/adea02 PMID: 40588003

Deciphering the language of mingling lipids and proteins.

Overduin M, Bhat R, Dieudonné T, Zhang P, Kervin TA

Current opinion in structural biology2025First author

DOI: 10.1016/j.sbi.2025.103061 PMID: 40339327

Development of a succinyl CoA:3-ketoacid CoA transferase inhibitor selective for peripheral tissues that improves glycemia in obesity.

Tabatabaei Dakhili SA, Yang K, Al Nebaihi H, Greenwell AA, Wuest M, Woodfield J, Farraj RA, Saed CT, Chan JSF, Bhat RK, Mangra-Bala IA, Shafaati T, Gopal K, Eaton F, Ferrari SR, Wagg CS, Capozzi ME, Campbell JE, Overduin M, Velazquez-Martinez CA, Glover JNM, Wuest F, Brocks DR, Ussher JR

iScience2025

DOI: 10.1016/j.isci.2025.112336 PMID: 40454095

Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

Chan JSF, Tabatabaei Dakhili SA, Lorenzana-Carrillo MA, Gopal K, Pulente SM, Greenwell AA, Yang K, Saed CT, Stenlund MJ, Ferrari SR

Cell reports202417 citations

DOI: 10.1016/j.celrep.2024.114573

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Michael Overduin

Research

Latest papers

Latest funding

Membrane Models and the Pursuit of Coherence.

Nucleotide-dependent domain interactions of Aha1-type co-chaperones with Hsp90 reveal evolutionarily conserved binding determinants.

Proteomic Snapshots of Structural Cross-Linking Rearrangements in Ca2+/Calmodulin-Dependent Kinase-1-Delta Associated with Its Regulation by ATP, Ca2+/Calmodulin, and Reduction Potential.

Structural insights into the binding modes of SHP2 allosteric inhibitors.

Design of zwitterionic fluorescent polymers for membrane protein solubilization into native nanodiscs

The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts.

Molecular mechanisms associated with the interaction of external electromagnetic fields in protein dynamics and aggregation: a focus on amyloid-βpeptide.

Deciphering the language of mingling lipids and proteins.

Development of a succinyl CoA:3-ketoacid CoA transferase inhibitor selective for peripheral tissues that improves glycemia in obesity.

Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

Exploitation of Lipid Codons for Pharmaceutical and Biotech Industry Growth

Extension of the Biological Code through the Proteolipid Code

Functional Derivatives of Maleic Acid copolymers and Native Nanodisc Technology (FUNDEMANNT) [Phase 1]

Bacterial outer membrane biogenesis through a novel periplasmic protein that recognizes and traffics phospholipids

System for Resolving Native Membrane Nanodiscs and Protein Assemblies

Frequent collaborators

Holger Wille

Klaus Ballanyi

Paul LaPointe

Thomas Simmen

Gary Eitzen

Larry Fliegel

Gopinath Sutendra

Frank Wuest

Michael Zaugg

Frederick West

Liang Li

Gregory Steinberg

Thorsten Dieckmann

Russell Bishop

Satyabrata Kar

David Westaway

Michael Overduin

Research

Latest papers

Latest funding

Membrane Models and the Pursuit of Coherence.

Nucleotide-dependent domain interactions of Aha1-type co-chaperones with Hsp90 reveal evolutionarily conserved binding determinants.

Proteomic Snapshots of Structural Cross-Linking Rearrangements in Ca2+/Calmodulin-Dependent Kinase-1-Delta Associated with Its Regulation by ATP, Ca2+/Calmodulin, and Reduction Potential.

Structural insights into the binding modes of SHP2 allosteric inhibitors.

Design of zwitterionic fluorescent polymers for membrane protein solubilization into native nanodiscs

The ER thioredoxin-related transmembrane protein TMX2 controls redox-mediated tethering of ER-mitochondria contacts.

Molecular mechanisms associated with the interaction of external electromagnetic fields in protein dynamics and aggregation: a focus on amyloid-&#x3b2;peptide.

Deciphering the language of mingling lipids and proteins.

Development of a succinyl CoA:3-ketoacid CoA transferase inhibitor selective for peripheral tissues that improves glycemia in obesity.

Growth differentiation factor 15 alleviates diastolic dysfunction in mice with experimental diabetic cardiomyopathy

Exploitation of Lipid Codons for Pharmaceutical and Biotech Industry Growth

Extension of the Biological Code through the Proteolipid Code

Functional Derivatives of Maleic Acid copolymers and Native Nanodisc Technology (FUNDEMANNT) [Phase 1]

Bacterial outer membrane biogenesis through a novel periplasmic protein that recognizes and traffics phospholipids

System for Resolving Native Membrane Nanodiscs and Protein Assemblies

Frequent collaborators

Holger Wille

Klaus Ballanyi

Paul LaPointe

Thomas Simmen

Gary Eitzen

Larry Fliegel

Gopinath Sutendra

Frank Wuest

Michael Zaugg

Frederick West

Liang Li

Gregory Steinberg

Thorsten Dieckmann

Russell Bishop

Satyabrata Kar

David Westaway

Molecular mechanisms associated with the interaction of external electromagnetic fields in protein dynamics and aggregation: a focus on amyloid-βpeptide.