Faculty profile

Andrew Roth

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Associate ProfessorUniversity of British Columbia

Andrew Roth

Associate Professor

University of British Columbia

Vancouver, British Columbia, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
19 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 2 research grants (2 NSERC), most recently in 2022.
Supervisor on 3 trainee awards (3 CIHR), most recently in 2025.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Read how they describe their research on their University of British Columbia profile.

Latest papers

Mast cell-derived IL-13 as a driver of Crohn disease-associated intestinal fibrosis.
Inflammatory bowel diseases · 2026
Multidimensional Characterization of Tumor-Immune Architecture Reveals Clinically Relevant Classic Hodgkin Lymphoma Subtypes.
Cancer discovery · 2026
Single-cell spatial atlas of the aging human breast.
Nature aging · 2026

All 36 publications

Latest funding

Bayesian Methods for Characterizing Cancer Evolution Across Sequencing Technologies and Strategies
CIHR · 2025 · Supervisor
$120,000
Bayesian machine learning methods for clonal inference
CIHR · 2025 · Supervisor
$120,000
Cellular ecosystems of nodular lymphocyte predominant Hodgkin lymphoma
CIHR · 2024 · Co-investigator
$1,147,500

All 9 grants and awards

36 publications.

Mast cell-derived IL-13 as a driver of Crohn disease-associated intestinal fibrosis.

Safari K, Ma WJ, Sekhon P, Rai P, Menzies SC, Hoshino T, Fratzscher AS, Roth A, Madsen K, Sly LM

Inflammatory bowel diseases2026

DOI: 10.1093/ibd/izag127 PMID: 42418669

Multidimensional Characterization of Tumor-Immune Architecture Reveals Clinically Relevant Classic Hodgkin Lymphoma Subtypes.

Aoki T, Duns G, Rai S, Jiang A, Lytle A, Yin Y, Kishida M, Yu Li M, Lee C, Smorra D, Hilton LK, Healy S, Alig SK, Shahrokh Esfahani M, Sarkozy C, Hung SS, Milne K, Telenius A, O'Brien L, Wong JCH, Cassidy C, Fujisawa M, Strong C, Goodyear T, Di Vito C, Luksik C, Edin G, Gonzalez L, Rangel Patiño J, Hong M, Wu S, Lee E, Sakhdari A, Takata K, Miyata-Takata T, Boyle M, Ben-Neriah S, Weng AP, Xu A, Merchant A, Roth A, Crump M, Kuruvilla J, Prica A, Kridel R, Huntsman DG, Nelson BH, Farinha P, Morin RD, Alizadeh AA, Savage KJ, Scott DW, Steidl C

Cancer discovery2026

DOI: 10.1158/2159-8290.cd-25-0859 PMID: 41615883

Single-cell spatial atlas of the aging human breast.

Gupta P, Lee E, Masqué Soler N, Schrader E, Wang XQ, Mayer S, Flores C, Beatty S, Roth A, Aparicio S, Ali HR

Nature aging2026

DOI: 10.1038/s43587-026-01104-3 PMID: 41917190

Spatial single cell transcriptomic analysis informs tumor developmental hierarchy of DICER1 syndrome related sarcoma.

Kommoss FKF, Zhang JYH, Lynch BJ, Chen SY, Senz J, Moscovitz Y, Hill LA, Ma D, Scott RW, Bush J, Chen KS, Roth A, von Deimling A, Foulkes WD, Morin GB, Underhill TM, Wang Y, Huntsman DG

Nature communications2026

DOI: 10.1038/s41467-026-70971-6 PMID: 41912509

Pre-diagnostic serum metabolome and breast cancer risk: a nested case-control study.

Trinh L, Parks J, McDonald T, Roth A, Shen-Tu G, Vena J, Murphy RA, Bhatti P

Breast cancer research : BCR2025

DOI: 10.1186/s13058-025-02102-w PMID: 40867009

PhyClone: accurate Bayesian reconstruction of cancer phylogenies from bulk sequencing.

Hurtado E, Bouchard-Côté A, Roth A

Bioinformatics (Oxford, England)2025Senior author

DOI: 10.1093/bioinformatics/btaf344 PMID: 40511985

CopyMix: Mixture model based single-cell clustering and copy number profiling using variational inference.

Safinianaini N, De Souza CPE, Roth A, Koptagel H, Toosi H, Lagergren J

Computational biology and chemistry2024

DOI: 10.1016/j.compbiolchem.2024.108257 PMID: 39500117

Single-cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers.

Kabeer F, Tran H, Andronescu M, Singh G, Lee H, Salehi S, Wang B, Biele J, Brimhall J, Gee D, Cerda V, O'Flanagan C, Algara T, Kono T, Beatty S, Zaikova E, Lai D, Lee E, Moore R, Mungall AJ, IMAXT Consortium, Williams MJ, Roth A, Campbell KR, Shah SP, Aparicio S

Genome biology2024

DOI: 10.1186/s13059-024-03318-3 PMID: 39026273

Integrated single cell analysis reveals co-evolution of malignant B cells and tumor micro-environment in transformed follicular lymphoma.

Sarkozy C, Wu S, Takata K, Aoki T, Neriah SB, Milne K, Goodyear T, Strong C, Rastogi T, Hilton LK, Lai D, Sehn LH, Farinha P, Nelson BH, Weng A, Marra M, Scott DW, Craig JW, Steidl C, Roth A

Cancer cell2024Senior author

DOI: 10.1016/j.ccell.2024.05.011 PMID: 38861923

Spatially Resolved Tumor Microenvironment Predicts Treatment Outcomes in Relapsed/Refractory Hodgkin Lymphoma.

Aoki T, Jiang A, Xu A, Yin Y, Gamboa A, Milne K, Takata K, Miyata-Takata T, Chung S, Rai S, Wu S, Warren M, Strong C, Goodyear T, Morris K, Chong LC, Hav M, Colombo AR, Telenius A, Boyle M, Ben-Neriah S, Power M, Gerrie AS, Weng AP, Karsan A, Roth A, Farinha P, Scott DW, Savage KJ, Nelson BH, Merchant A, Steidl C

Journal of clinical oncology : official journal of the American Society of Clinical Oncology2024

DOI: 10.1200/jco.23.01115 PMID: 38113419

Bayesian Methods for Characterizing Cancer Evolution Across Sequencing Technologies and Strategies

SupervisorCIHR2025Doctoral Research Award - PA - Bioinformatics and Computational Biology

Principal investigators: Hurtado, Emilia

Keywords: Bayesian Non-Parametrics; Bioinformatics; Cancer; Cancer Evolution; Genomics; Multiomics; Phylogenetics; Probabilistic Modelling; Single-Cell Sequencing; Transcriptomics

$120,000

Bayesian machine learning methods for clonal inference

SupervisorCIHR2025DRA : Canada Graduate Research Scholarship - Doctoral Program (CGRS D)

Principal investigators: Breen, Katherine

Keywords: Bayesian Machine Learning; Bioinformatics; Cancer Genomics

$120,000

Cellular ecosystems of nodular lymphocyte predominant Hodgkin lymphoma

Co-investigatorCIHR2024Project Grant

Principal investigators: Steidl, Christian

Keywords: Clonal Evolution; Gene Editing; Gene Mutations; Lymphoma; Pathogenesis; Targeted Therapy; Tumour Microenvironment

$1,147,500

Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer

Co-investigatorCIHR2023Project Grant

Principal investigators: Aparicio, Samuel J

Keywords: Cancer; Genomic Instability; Single Cell Analysis; Therapeutics

$1,040,400

Computational approaches for exploring the spatial dynamics of the cellular ecosystem

SupervisorCIHR2023Doctoral Research Award: Canada Graduate Scholarships

Principal investigators: Lee, Eric

Keywords: Cancer Progression; Computational Biology / Bioinformatics; Machine Learning; Probabilistic Bayesian Modeling; Single Cell Methods; Spatial-Omics

$105,000

Clonal interactions in myeloid malignancy

Co-investigatorCIHR2022Project Grant

Principal investigators: Karsan, Aly

Keywords: Clonal Interactions; Clonal Tracking; H2s; Leukemia; Leukemic Stem Cells; Oxidative Phosphorylation; Single Cell Sequencing; Ubiquitylation

$1,025,100

Computational Methods for Single Cell Biology

Principal investigatorNSERC2022Discovery Grants Program - Individual

Principal investigators: Roth, Andrew

Keywords: genomics; single cell omics; bayesian statistics; spatial omics; computational statistics

$87,000

Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer.

Co-investigatorCIHR2022Project Grant

Principal investigators: Aparicio, Samuel J

Keywords: Cancer

$100,000

Computational Methods for Single Cell Biology

Principal investigatorNSERC2022Discovery Launch Supplement

Principal investigators: Roth, Andrew

$12,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Profile data last refreshed on September 27, 2026 from the university directory, publication records and CIHR, NSERC and SSHRC funding.

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Andrew Roth

Research

Latest papers

Latest funding

Mast cell-derived IL-13 as a driver of Crohn disease-associated intestinal fibrosis.

Multidimensional Characterization of Tumor-Immune Architecture Reveals Clinically Relevant Classic Hodgkin Lymphoma Subtypes.

Single-cell spatial atlas of the aging human breast.

Spatial single cell transcriptomic analysis informs tumor developmental hierarchy of DICER1 syndrome related sarcoma.

Pre-diagnostic serum metabolome and breast cancer risk: a nested case-control study.

PhyClone: accurate Bayesian reconstruction of cancer phylogenies from bulk sequencing.

CopyMix: Mixture model based single-cell clustering and copy number profiling using variational inference.

Single-cell decoding of drug induced transcriptomic reprogramming in triple negative breast cancers.

Integrated single cell analysis reveals co-evolution of malignant B cells and tumor micro-environment in transformed follicular lymphoma.

Spatially Resolved Tumor Microenvironment Predicts Treatment Outcomes in Relapsed/Refractory Hodgkin Lymphoma.

Bayesian Methods for Characterizing Cancer Evolution Across Sequencing Technologies and Strategies

Bayesian machine learning methods for clonal inference

Cellular ecosystems of nodular lymphocyte predominant Hodgkin lymphoma

Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer

Computational approaches for exploring the spatial dynamics of the cellular ecosystem

Clonal interactions in myeloid malignancy

Computational Methods for Single Cell Biology

Decoding the impact of single cell mutational processes in triple negative breast cancer and high grade serous ovarian cancer.

Computational Methods for Single Cell Biology

Frequent collaborators

Samuel Aparicio

Christian Steidl

Ali Bashashati

Jiarui Ding

Martin Hirst

John Kuruvilla

Aly Karsan

Robert Kridel

Steven Jones

Sohrab Shah

Inanc Birol

Adi Steif

Anne Condon

Michael Anglesio

Marco Marra

Karen Madsen

Yemin Wang

Kevin Song

David Huntsman

Parveen Bhatti

Andrew Weng