This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses and email address may be missing. Find their university profile.
Research
Latest papers
Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes.
Nature communications · 2025
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
Molecular systems biology · 2024
Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.
Cancer discovery · 2022 · first author
Latest funding
- $95,000
In vivo screening of environmental and genetic determinants of metastatic breast cancer
CIHR · 2023 · Nominated PI
6 publications.
Topoisomerase IIb binding delineates localized mutational processes and driver mutations in cancer genomes.
Uusküla-Reimand L, Lee CA, Oh RH, Klein ZP, Adler N, Akhtar Alvi S, Langille E, Pasini E, Cheng KCL, Serafimova E, Abd-Rabbo D, Hou H, Tsai R, Bhat M, Schramek D, Wilson MD, Reimand J
Genome-wide CRISPR screens identify novel regulators of wild-type and mutant p53 stability.
Lü Y, Cho T, Mukherjee S, Suarez CF, Gonzalez-Foutel NS, Malik A, Martinez S, Dervovic D, Oh RH, Langille E, Al-Zahrani KN, Hoeg L, Lin ZY, Tsai R, Mbamalu G, Rotter V, Ashton-Prolla P, Moffat J, Chemes LB, Gingras AC, Oren M, Durocher D, Schramek D
Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.
Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD, Egan SE, Cescon DW, Sørlie T, Wrana JL, Jackson HW, Wilson MD, Witkiewicz AK, Knudsen ES, Pujana MA, Wahl GM, Schramek D
Binary pan-cancer classes with distinct vulnerabilities defined by pro- or anti-cancer YAP/TEAD activity.
Pearson JD, Huang K, Pacal M, McCurdy SR, Lu S, Aubry A, Yu T, Wadosky KM, Zhang L, Wang T, Gregorieff A, Ahmad M, Dimaras H, Langille E, Cole SPC, Monnier PP, Lok BH, Tsao MS, Akeno N, Schramek D, Wikenheiser-Brokamp KA, Knudsen ES, Witkiewicz AK, Wrana JL, Goodrich DW, Bremner R
Rare driver mutations in head and neck squamous cell carcinomas converge on NOTCH signaling.
Loganathan SK, Schleicher K, Malik A, Quevedo R, Langille E, Teng K, Oh RH, Rathod B, Tsai R, Samavarchi-Tehrani P, Pugh TJ, Gingras AC, Schramek D
ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells.
Park NI, Guilhamon P, Desai K, McAdam RF, Langille E, O'Connor M, Lan X, Whetstone H, Coutinho FJ, Vanner RJ, Ling E, Prinos P, Lee L, Selvadurai H, Atwal G, Kushida M, Clarke ID, Voisin V, Cusimano MD, Bernstein M, Das S, Bader G, Arrowsmith CH, Angers S, Huang X, Lupien M, Dirks PB
In vivo screening of environmental and genetic determinants of metastatic breast cancer
Principal investigators: Langille, Ellen
Keywords: Cancer
From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.
Frequent collaborators
- Lunenfeld-Tanenbaum Research Institute
- Terrence Donnelly Centre for Cellular and Biomolecular Research
- Department of Molecular Genetics
- Clinical Public Health Division
- Genetics and Genome Biology
- Transplant Program
- Department of Surgery
- Other
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Daniel Schramek
Lunenfeld-Tanenbaum Research Institute
5 shared papers, latest 2025
Rod Bremner
Lunenfeld-Tanenbaum Research Institute
2 shared papers, latest 2022
Anne-Claude Gingras
Department of Molecular Genetics
2 shared papers, latest 2024
Mark Bernstein
Department of Surgery
1 shared papers, latest 2017
Ming-Sound Tsao
Department of Laboratory Medicine and Pathobiology
1 shared papers, latest 2021
Helen Dimaras
Clinical Public Health Division
1 shared papers, latest 2021
Gary Bader
Terrence Donnelly Centre for Cellular and Biomolecular Research
1 shared papers, latest 2017
Sunit Das
Surgery
1 shared papers, latest 2017
Jason Moffat
Genetics and Genome Biology
1 shared papers, latest 2024
Xi Huang
Faculty
1 shared papers, latest 2017
Alex Gregorieff
Faculty
1 shared papers, latest 2021
Stephane Angers
Terrence Donnelly Centre for Cellular and Biomolecular Research
1 shared papers, latest 2017
Mamatha Bhat
Transplant Program
1 shared papers, latest 2025
Mathieu Lupien
Medical Biophysics
1 shared papers, latest 2017
Daniel Durocher
Lunenfeld-Tanenbaum Research Institute
1 shared papers, latest 2024
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