Faculty profile

Rod Bremner

ResearcherLunenfeld-Tanenbaum Research InstituteUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Rod Bremner

Researcher

Lunenfeld-Tanenbaum Research Institute

Health Sciences

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
13 publications in the last five years, latest in 2025.
Senior (last) author on 4 recent papers, a sign of leading a research group.
Principal investigator on 9 research grants (9 CIHR), most recently in 2025.
Supervised 3 trainees who won CIHR awards, most recently in 2026.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

h-index

Collaborators

Grants

Publications by year

Counts cover the works listed on the university profile; citation counts come from Dimensions.

Profiles and links

Search on Google Scholar

Find them onX · LinkedIn · Bluesky · YouTube

Signals and details

Research

Yap Drug Resistance Small Cell Lung Cancer (Sclc)Anchorage Independent Growth Assays Cell Cycle Rate Chromatin Accessibility Lineage Specific Cancer Susceptibility Murine Cancer Models (Retina, Pituitary, Lung)

Latest papers

Cell cycle duration determines oncogenic transformation capacity.
Nature · 2025 · senior author
SUMOylation of the lysine-less tumor suppressor p14ARF counters ubiquitylation-dependent degradation.
Cell death & disease · 2025
Validation of new equipment for SARS-CoV-2 diagnosis in Ecuador: Detection of the virus and antibodies generated by disease and vaccines with one POC device.
PloS one · 2025

All 57 publications

Latest funding

Predicting neoplastic transformation capacity
CIHR · 2026 · Supervisor
$140,000
Determinants of transformation potential
CIHR · 2025 · Nominated PI
$100,000
Role of YAP and TAZ in Acute Myeloid Leukemia
CIHR · 2022 · Nominated PI
$902,700

All 14 grants and awards

57 publications.

Cell cycle duration determines oncogenic transformation capacity.

Chen D, Lu S, Huang K, Pearson JD, Pacal M, Peidis P, McCurdy S, Yu T, Sangwan M, Nguyen A, Monnier PP, Schramek D, Zhu L, Santamaria D, Barbacid M, Akeno N, Wikenheiser-Brokamp KA, Bremner R

Nature2025Senior author

DOI: 10.1038/s41586-025-08935-x PMID: 40307557

SUMOylation of the lysine-less tumor suppressor p14ARF counters ubiquitylation-dependent degradation.

El Motiam A, Bouzaher YH, Chen H, Seoane R, Vidal S, Blanquer M, Tolosa RM, Rodríguez-Lemus B, Herrera-Gavilán JA, Vidal A, Palmero I, Rodríguez MS, Sutherland JD, Barrio R, Xirodimas D, Collado M, Bremner R, Rivas C

Cell death & disease2025

DOI: 10.1038/s41419-025-07854-z PMID: 40651945

Validation of new equipment for SARS-CoV-2 diagnosis in Ecuador: Detection of the virus and antibodies generated by disease and vaccines with one POC device.

Villota SD, Veloz-Villavicencio E, Garcia-Iturralde S, Arévalo JV, Lu S, Jaenes K, Guo Y, Cicek S, Colwill K, Gingras AC, Bremner R, Ponce P, Pardee K, Cevallos VE

PloS one2025

DOI: 10.1371/journal.pone.0321794 PMID: 40238804

Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis.

Pearson JD, Huang K, Dela Pena LG, Ducarouge B, Mehlen P, Bremner R

Cancer research communications2024Senior author

DOI: 10.1158/2767-9764.crc-24-0101 PMID: 39172021

Progenitor division and cell autonomous neurosecretion are required for rod photoreceptor sublaminar positioning.

Gurdita A, Pham Truong VQB, Dolati P, Juric M, Tachibana N, Liu ZC, Ortín-Martínez A, Ibrahimi M, Pokrajac NT, Comanita L, Pacal M, Huang M, Sugita S, Bremner R, Wallace VA

Proceedings of the National Academy of Sciences of the United States of America2023

DOI: 10.1073/pnas.2308204120 PMID: 37812728

Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses.

Aubry A, Pearson JD, Charish J, Yu T, Sivak JM, Xirodimas DP, Avet-Loiseau H, Corre J, Monnier PP, Bremner R

Cell reports2023Senior author

DOI: 10.1016/j.celrep.2023.112925 PMID: 37552601

Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.

Langille E, Al-Zahrani KN, Ma Z, Liang M, Uuskula-Reimand L, Espin R, Teng K, Malik A, Bergholtz H, Ghamrasni SE, Afiuni-Zadeh S, Tsai R, Alvi S, Elia A, Lü Y, Oh RH, Kozma KJ, Trcka D, Narimatsu M, Liu JC, Nguyen T, Barutcu S, Loganathan SK, Bremner R, Bader GD, Egan SE, Cescon DW, Sørlie T, Wrana JL, Jackson HW, Wilson MD, Witkiewicz AK, Knudsen ES, Pujana MA, Wahl GM, Schramek D

Cancer discovery2022

DOI: 10.1158/2159-8290.cd-21-0865 PMID: 36108220

Translational feasibility and efficacy of nasal photodynamic disinfection of SARS-CoV-2.

Pires L, Wilson BC, Bremner R, Lang A, Larouche J, McDonald R, Pearson JD, Trcka D, Wrana J, Wu J, Whyne CM

Scientific reports2022

DOI: 10.1038/s41598-022-18513-0 PMID: 36002557

Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application.

Lu S, Duplat D, Benitez-Bolivar P, León C, Villota SD, Veloz-Villavicencio E, Arévalo V, Jaenes K, Guo Y, Cicek S, Robinson L, Peidis P, Pearson JD, Woodgett J, Mazzulli T, Ponce P, Restrepo S, González JM, Bernal A, Guevara-Suarez M, Pardee K, Cevallos VE, González C, Bremner R

PloS one2022Senior author

DOI: 10.1371/journal.pone.0268340 PMID: 35544541

Mapping transgene insertion sites reveals the α-Cre transgene expression in both developing retina and olfactory neurons.

Fan Y, Chen W, Wei R, Qiang W, Pearson JD, Yu T, Bremner R, Chen D

Communications biology2022

DOI: 10.1038/s42003-022-03379-9 PMID: 35505181

Predicting neoplastic transformation capacity

SupervisorCIHR2026Fellowship: Canada Impact+ Research Training Awards - Postdoctoral

Principal investigators: Ducau, Charlotte

Keywords: Cancer; Chromatin; Initiation; Mouse Model; Promotion; Transcription

$140,000

Determinants of transformation potential

Nominated PICIHR2025Project Grant - Priority Announcement: Early Detection/Cancer Prevention

Principal investigators: Bremner, Rod

Keywords: Anchorage Independent Growth Assays; Cell Cycle Rate; Chromatin Accessibility; Lineage Specific Cancer Susceptibility; Murine Cancer Models (Retina, Pituitary, Lung); Single Cell Genomics (10x Scrnaseq, Scatacseq); Transcriptional Diversity; Transformation Potential

$100,000

Role of YAP and TAZ in Acute Myeloid Leukemia

Nominated PICIHR2022Project Grant

Principal investigators: Bremner, Rod

Keywords: Acute Myeloid Leukemia; Bioid, Proteomics; Bone Marrow Niche; Co-Culture Systems; Drug Resistance; Flt3 Inhibitors; Lsd1 Inhibitors; Taz, Wwtr1; Tead; Yap

$902,700

Dissecting the Tumor Suppressor Function of YAP in Neural and Neuroendocrine Cancers

Nominated PICIHR2021Project Grant

Principal investigators: Bremner, Rod

Keywords: Bioid; Crispri; Ip-Mass Spec; Neural Cancer; Neuroendocrine Cancer; Small Cell Lung Cancer (Sclc); Taz/Wwtr1; Yap

$1,013,625

Portable, Low-cost Hardware for De-centralized COVID-19 Diagnostics for Canada, Colombia and Ecuador

Co-investigatorCIHR2020Operating Grant: COVID-19 Rapid Research Funding Opportunity - Diagnostics

Principal investigators: Pardee, Keith I; Cevallos, Varsovia E; Gonzalez, Camila

Keywords: Covid-19 Serological Testing; De-Centralized Diagnostic Capacity; Elisa; Low-Cost Diagnostic Hardware; Rt-Lamp; Sars-Cov-2 Diagnostics

The Single Cell Biology of Context-Specific Responses to Loss of the RB Tumor Suppressor Gene

Nominated PICIHR2020Project Grant

Principal investigators: Bremner, Rod

Keywords: Cancer; Cdk2; Cell Of Origin; Hypertranscription; Rb Tumor Suppressor Gene; Single Cell Rnaseq; Susceptibility Versus Resistance

$801,720

Resistance to established and new RET oncogene inhibitors

Nominated PICIHR2019Project Grant - PA: Epigenetics/epigenomics in human health or disease

Principal investigators: Bremner, Rod

Keywords: Crispr/Cas9 Screen; Drug Resistance; Drug Synergy; Lung Cancer; Receptor Tyrosine Kinase Signaling; Thyroid Cancer

$100,000

Opposite roles of MYCN and YAP in cancer initiation

Nominated PICIHR2016Project Grant

Principal investigators: Bremner, Rod

Keywords: Murine Models Of Cancer; Mycn; Neurogenesis; Rb; Retina And Lung Explants; Retinoblastoma; Small Cell Lung Cancer (Sclc); Yap

$726,750

Determining the molecular pathways that regulate mammalian cell competition

SupervisorCIHR2014CIHR Fellowship

Principal investigators: Pearson, Joel

Keywords: Cancer Cell Signalling; Cancer Initiation; Cell Biology; Cell Competition; Cell-Cell Communication; High Throughput Screening

$135,000

Investigation of RNAi strategies to treat Retinoblastoma and other ocular diseases

SupervisorCIHR2010Master's Award: Canada Graduate Scholarships

Principal investigators: McCurdy, Sean

Keywords: Cancer Stem Cells; Cancer Therapy; Cdk Inhibitors; Cell Cycle; Drug Delivery; Fluorescent Microscopy; Knockout Mice; Retinoblastoma Protein; Rnai; Tumorigenesis

$17,500

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

Something wrong or missing on this profile? Suggest a correction

Rod Bremner

Research

Latest papers

Latest funding

Cell cycle duration determines oncogenic transformation capacity.

SUMOylation of the lysine-less tumor suppressor p14ARF counters ubiquitylation-dependent degradation.

Validation of new equipment for SARS-CoV-2 diagnosis in Ecuador: Detection of the virus and antibodies generated by disease and vaccines with one POC device.

Netrin-1 and UNC5B Cooperate with Integrins to Mediate YAP-Driven Cytostasis.

Progenitor division and cell autonomous neurosecretion are required for rod photoreceptor sublaminar positioning.

Deneddylation of ribosomal proteins promotes synergy between MLN4924 and chemotherapy to elicit complete therapeutic responses.

Loss of Epigenetic Regulation Disrupts Lineage Integrity, Induces Aberrant Alveogenesis, and Promotes Breast Cancer.

Translational feasibility and efficacy of nasal photodynamic disinfection of SARS-CoV-2.

Multicenter international assessment of a SARS-CoV-2 RT-LAMP test for point of care clinical application.

Mapping transgene insertion sites reveals the &#x3b1;-Cre transgene expression in both developing retina and olfactory neurons.

Frequent collaborators

Tony Mazzulli

Daniel Schramek

Keith Pardee

Laurence Pelletier

Eldad Zacksenhaus

Liliana Attisano

Ellen Langille

Helen McNeill

Shuzo Sugita

Derek van der Kooy

Anne-Claude Gingras

Carol Schuurmans

Bradley Pickering

Michael Reber

Susan Poutanen

Alex Gregorieff

Jim Hu

Andras Nagy

Igor Jurisica

Jean-Francois Cloutier

Gautam Awatramani

Michael Moran

Karen Mossman

Lea Harrington

Ming-Sound Tsao

Helen Dimaras

David Sinton

Mapping transgene insertion sites reveals the α-Cre transgene expression in both developing retina and olfactory neurons.