Faculty profile

Karim Nader

ResearcherPsychologyMcGill University

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a McGill University directory, so their courses may be missing. Find their university profile.

Karim Nader

Researcher

Psychology

Health Sciences

McGill University

Montreal, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
6 publications in the last five years, latest in 2026.
Senior (last) author on 2 recent papers, a sign of leading a research group.
Principal investigator on 10 research grants (5 NSERC, 5 CIHR), most recently in 2017.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Receptor Trafficking Electrophysiology Memory Fear Conditioning Protein Synthesis Retrieval Aging Forgetting

Latest papers

Genetic Reduction of the Translational Repressors FMRP and 4E-BP2 Preserves Memory in Mouse Models of Alzheimer's Disease.
Aging cell · 2026
The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease.
Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
KIBRA anchoring the action of PKMζ maintains the persistence of memory.
Science advances · 2024

All 56 publications

Latest funding

The Role of PKMzeta in Memory Destabilization and Reconsolidation
NSERC · 2017 · Principal investigator
$234,000
Understanding the neurobiology of memory retrieval
CIHR · 2016 · Nominated PI
$459,000
The effect of chronic anti-hypertensive treatment on emotional and autobiographical memory
CIHR · 2016 · Co-investigator
$439,589

All 12 grants and awards

56 publications.

Genetic Reduction of the Translational Repressors FMRP and 4E-BP2 Preserves Memory in Mouse Models of Alzheimer's Disease.

Ribeiro FC, Cozachenco D, Parkhill M, Rodrigue B, Borges C, Lacaille JC, Nader K, De Felice FG, Lourenco MV, Aguilar-Valles A, Sonenberg N, Ferreira ST

Aging cell2026

DOI: 10.1111/acel.70315 PMID: 41334801

The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease.

Ribeiro FC, Cozachenco D, Argyrousi EK, Staniszewski A, Wiebe S, Calixtro JD, Soares-Neto R, Al-Chami A, Sayegh FE, Bermudez S, Arsenault E, Cossenza M, Lacaille JC, Nader K, Sun H, De Felice FG, Lourenco MV, Arancio O, Aguilar-Valles A, Sonenberg N, Ferreira ST

Alzheimer's & dementia : the journal of the Alzheimer's Association2024

DOI: 10.1002/alz.14034 PMID: 38934107

KIBRA anchoring the action of PKMζ maintains the persistence of memory.

Tsokas P, Hsieh C, Flores-Obando RE, Bernabo M, Tcherepanov A, Hernández AI, Thomas C, Bergold PJ, Cottrell JE, Kremerskothen J, Shouval HZ, Nader K, Fenton AA, Sacktor TC

Science advances2024

DOI: 10.1126/sciadv.adl0030 PMID: 38924398

Network-level changes in the brain underlie fear memory strength.

Haubrich J, Nader K

eLife2023Senior author

DOI: 10.7554/elife.88172 PMID: 38047914

Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome.

Hooshmandi M, Sharma V, Thörn Perez C, Sood R, Krimbacher K, Wong C, Lister KC, Ureña Guzmán A, Bartley TD, Rocha C, Maussion G, Nadler E, Roque PM, Gantois I, Popic J, Lévesque M, Kaufman RJ, Avoli M, Sanz E, Nader K, Hagerman RJ, Durcan TM, Costa-Mattioli M, Prager-Khoutorsky M, Lacaille JC, Martinez-Cerdeno V, Gibson JR, Huber KM, Sonenberg N, Gkogkas CG, Khoutorsky A

Neuron2023

DOI: 10.1016/j.neuron.2023.06.017 PMID: 37473758

A novel stress-based intervention reduces cigarette use in non-treatment seeking smokers.

Barnabe A, Gamache K, de Camargo JVP, Allen-Flanagan E, Rioux M, Pruessner J, Leyton M, Nader K

Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology2023Senior author

DOI: 10.1038/s41386-022-01455-6 PMID: 36175551

Memory Destabilization and Reconsolidation Dynamically Regulate the PKMζ Maintenance Mechanism.

Bernabo M, Haubrich J, Gamache K, Nader K

The Journal of neuroscience : the official journal of the Society for Neuroscience2021Senior author

DOI: 10.1523/jneurosci.2093-20.2021 PMID: 33888608

eIF2α controls memory consolidation via excitatory and somatostatin neurons.

Sharma V, Sood R, Khlaifia A, Eslamizade MJ, Hung TY, Lou D, Asgarihafshejani A, Lalzar M, Kiniry SJ, Stokes MP, Cohen N, Nelson AJ, Abell K, Possemato AP, Gal-Ben-Ari S, Truong VT, Wang P, Yiannakas A, Saffarzadeh F, Cuello AC, Nader K, Kaufman RJ, Costa-Mattioli M, Baranov PV, Quintana A, Sanz E, Khoutorsky A, Lacaille JC, Rosenblum K, Sonenberg N

Nature2020

DOI: 10.1038/s41586-020-2805-8 PMID: 33029011

Impairments to Consolidation, Reconsolidation, and Long-Term Memory Maintenance Lead to Memory Erasure.

Haubrich J, Bernabo M, Baker AG, Nader K

Annual review of neuroscience2020Senior author

DOI: 10.1146/annurev-neuro-091319-024636 PMID: 32097575

Noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation.

Haubrich J, Bernabo M, Nader K

eLife2020Senior author

DOI: 10.7554/elife.57010 PMID: 32420872

The Role of PKMzeta in Memory Destabilization and Reconsolidation

Principal investigatorNSERC2017Discovery Grants Program - Individual

Principal investigators: Nader, Karim

$234,000

Understanding the neurobiology of memory retrieval

Nominated PICIHR2016Project Grant

Principal investigators: Nader, Karim K

Keywords: Electrophysiology; Fear Conditioning; Memory; Protein Synthesis; Receptor Trafficking; Retrieval

$459,000

The effect of chronic anti-hypertensive treatment on emotional and autobiographical memory

Co-investigatorCIHR2016Project Grant

Principal investigators: Pruessner, Jens C

Keywords: Emotional Memory; Hypertension; Memory Consolidation; Neuroimaging; Propranolol

$439,589

The neurobiology of forgetting: The role and regulation of GluA2-dependent AMPA receptor endocytosis in constitutive forgetting and memory processing.

Nominated PICIHR2013Operating Grant

Principal investigators: Nader, Karim K

Keywords: Aging; Electrophysiology; Forgetting; Memory; Phamacological Agents; Receptor Trafficking; Viral Vectors

$658,800

Systematic Investigations into psychological, physiological and endocrinological effects of stress

Co-investigatorCIHR2012Operating Grant

Principal investigators: Pruessner, Jens C

Keywords: Alpha-Amylase; Attentional Bias; Cortisol; Gender; Psychoneuroendocrinology; Sex; Stress

$448,090

Identifying signalling pathways that regulate memory maintenance.

Nominated PICIHR2012Operating Grant

Principal investigators: Nader, Karim K

Keywords: Memory Maintenance; Plasticity; Receptor Trafficking

$632,200

Memory reorganization in the ACC and thalamus

Principal investigatorNSERC2011Discovery Grants Program - Individual

Principal investigators: Nader, Karim

$305,000

Ultra-centrifuge - Steacie Supplement

Principal investigatorNSERC2009Research Tools and Instruments - Category 1 (<$150,000)

Principal investigators: Nader, Karim

$67,953

Targetting reconsolidation of cocaine memories as a new treatment for cocaine addiction.

Nominated PICIHR2009Catalyst Grant: Prevention and Treatment of Illicit Substance Use

Principal investigators: Nader, Karim K; Leyton, Marco

Keywords: Addiction; Amnesic Agents; Reconsolidation Blockade

$99,966

The behavioral readout of long term plasticity is an active molecular process.

Nominated PICIHR2008Operating Grant

Principal investigators: Nader, Karim K

Keywords: Consolidation; Memory Expression; Plasticity; Receptor Trafficking

$684,030

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Karim Nader

Research

Latest papers

Latest funding

Genetic Reduction of the Translational Repressors FMRP and 4E-BP2 Preserves Memory in Mouse Models of Alzheimer's Disease.

The ketamine metabolite (2R,6R)-hydroxynorketamine rescues hippocampal mRNA translation, synaptic plasticity and memory in mouse models of Alzheimer's disease.

KIBRA anchoring the action of PKM&#x3b6; maintains the persistence of memory.

Network-level changes in the brain underlie fear memory strength.

Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome.

A novel stress-based intervention reduces cigarette use in non-treatment seeking smokers.

Memory Destabilization and Reconsolidation Dynamically Regulate the PKM&#x3b6; Maintenance Mechanism.

eIF2&#x3b1; controls memory consolidation via excitatory and somatostatin neurons.

Impairments to Consolidation, Reconsolidation, and Long-Term Memory Maintenance Lead to Memory Erasure.

Noradrenergic projections from the locus coeruleus to the amygdala constrain fear memory reconsolidation.

The Role of PKMzeta in Memory Destabilization and Reconsolidation

Understanding the neurobiology of memory retrieval

The effect of chronic anti-hypertensive treatment on emotional and autobiographical memory

The neurobiology of forgetting: The role and regulation of GluA2-dependent AMPA receptor endocytosis in constitutive forgetting and memory processing.

Systematic Investigations into psychological, physiological and endocrinological effects of stress

Identifying signalling pathways that regulate memory maintenance.

Memory reorganization in the ACC and thalamus

Ultra-centrifuge - Steacie Supplement

Targetting reconsolidation of cocaine memories as a new treatment for cocaine addiction.

The behavioral readout of long term plasticity is an active molecular process.

Frequent collaborators

Nahum Sonenberg

Oliver Hardt

Arkady Khoutorsky

Jean-Claude Lacaille

Masha Prager-Khoutorsky

Argel Aguilar Valles

Wayne Sossin

Argel Aguilar Valles

Jerry Pelletier

Marco Leyton

Massimo Avoli

Hongyu Sun

Alain Brunet

Nabil Seidah

Jens Pruessner

Marco Leyton

Kobi Rosenblum

Ruth Lanius

KIBRA anchoring the action of PKMζ maintains the persistence of memory.

Memory Destabilization and Reconsolidation Dynamically Regulate the PKMζ Maintenance Mechanism.

eIF2α controls memory consolidation via excitatory and somatostatin neurons.