Faculty profile
Avi Chakrabartty
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Read how they describe their research on their University of Toronto profile.
Latest papers
Proteolysis reconciles inconsistencies found in proteomic and cryo-EM studies of ATTR.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis · 2026 · first author
Structural Basis for Monoclonal Antibody Therapy for Transthyretin Amyloidosis.
Pharmaceuticals (Basel, Switzerland) · 2024 · first author
Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers.
eLife · 2017
Latest funding
- $1,241,973
Dynamic complexes and large-scale assemblies in neurobiology and disease
CFI · 2015 · Co-investigator
- $1,685,750
Regulation of the stress granule proteome and transcriptome by TDP-43 in ALS: biomarkers and therapeutic targets
BRAIN · 2015 · Co-investigator
- $1,950,000
CIHR Training Program in Protein Folding and Interaction Dynamics: Principles and Diseases
CIHR · 2008 · Co-investigator
8 publications.
Proteolysis reconciles inconsistencies found in proteomic and cryo-EM studies of ATTR.
Chakrabartty A
Structural Basis for Monoclonal Antibody Therapy for Transthyretin Amyloidosis.
Chakrabartty A
Somatostatin binds to the human amyloid β peptide and favors the formation of distinct oligomers.
Wang H, Muiznieks LD, Ghosh P, Williams D, Solarski M, Fang A, Ruiz-Riquelme A, Pomès R, Watts JC, Chakrabartty A, Wille H, Sharpe S, Schmitt-Ulms G
Interplay of buried histidine protonation and protein stability in prion misfolding
Anatoly Malevanets, P. Andrew Chong, D. Flemming Hansen, Paul J. Rizk, Yulong Sun, Hong Lin, Ranjith Muhandiram, Avijit Chakrabartty, Lewis E. Kay, Julie Deborah Forman-Kay, Shoshana J. Wodak
Structural and functional characterization of KEOPS dimerization by Pcc1 and its role in t6A biosynthesis.
Wan LC, Pillon MC, Thevakumaran N, Sun Y, Chakrabartty A, Guarné A, Kurinov I, Durocher D, Sicheri F
Cost-effective elimination of lipofuscin fluorescence from formalin-fixed brain tissue by white phosphor light emitting diode array.
Sun Y, Chakrabartty A
Binding of TDP-43 to the 3′UTR of Its Cognate mRNA Enhances Its Solubility
Yulong Sun, Pharhad Eli Arslan, Amy M. Won, Christopher M. Yip, Avijit Chakrabartty
Characterization of Segments from the Central Region of BRCA1: An Intrinsically Disordered Scaffold for Multiple Protein–Protein and Protein–DNA Interactions?
Wen-Ying Mark, Jack C. C. Liao, Ying Lü, Ayeda Ayed, Rob C. Laister, Blair R. Szymczyna, Avijit Chakrabartty, C.H. Arrowsmith
Dynamic complexes and large-scale assemblies in neurobiology and disease
Principal investigators: FORMAN-KAY, Julie
Keywords: neurodevelopment, neurodegeneration, brain, intrinsically disordered protein, structure, dynamics, interactions, large-scale assembly, amyloid, disease SAXS, DSC, NMR, thermal stage, nanoparticle tracking, bilayer interferometer
Regulation of the stress granule proteome and transcriptome by TDP-43 in ALS: biomarkers and therapeutic targets
Principal investigators: Velde, Christine Vande; Rouleau, Guy
Keywords: Neurodegeneration; ALS
CIHR Training Program in Protein Folding and Interaction Dynamics: Principles and Diseases
Principal investigators: Houry, Walid A; Forman-Kay, Julie D
Keywords: Absorbance; Alzheimer; Analytical Ultracentrifugation; Bacterial Infection; Bioinformatics; Cancer; Chaperones; Circular Dichroism; Computational Biology; Disease; Fluorescence; Folding; Microscopes; Misfolding; Nmr; Parkinson; Prions; Protein-Protein Interactions; Proteins; Proteomics; Training; X-Ray
Amino acid beta-sheet propensities
Principal investigators: Chakrabartty, Avijit
Protein Engineering Network of Centres of Excellence (PENCE)
Principal investigators: Withers, Stephen
From public funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998 with their latest competition results, the Canada Foundation for Innovation, Genome Canada, the Canadian Space Agency, Canada Research Chairs, the Fonds de recherche du Québec, Ontario research funding, Michael Smith Health Research BC, the Canadian Cancer Society, Heart & Stroke and Brain Canada.
Frequent collaborators
- Lewis Kay and Julie Forman-Kay: 63 shared papers
- Joel Watts and Gerold Schmitt-Ulms: 34 shared papers
- Frank Sicheri and Daniel Durocher: 30 shared papers
- Gerold Schmitt-Ulms and Holger Wille: 18 shared papers
- Joel Watts and Holger Wille: 15 shared papers
- Frank Sicheri and Julie Forman-Kay: 13 shared papers
- Cheryl Arrowsmith and Lewis Kay: 9 shared papers
- Régis Pomès and Simon Sharpe: 6 shared papers
- Frank Sicheri and Lewis Kay: 5 shared papers
- Christopher Yip and Simon Sharpe: 5 shared papers
- Cheryl Arrowsmith and Daniel Durocher: 4 shared papers
- Frank Sicheri and Cheryl Arrowsmith: 3 shared papers
- Frank Sicheri and Alba Guarne: 3 shared papers
- Cheryl Arrowsmith and Julie Forman-Kay: 3 shared papers
- Cheryl Arrowsmith and Ying Lu: 3 shared papers
- Lewis Kay and Simon Sharpe: 3 shared papers
- Christopher Yip and Régis Pomès: 2 shared papers
- Christopher Yip and Julie Forman-Kay: 2 shared papers
- Daniel Durocher and Lewis Kay: 2 shared papers
- Régis Pomès and Lewis Kay: 2 shared papers
- Régis Pomès and Joel Watts: 2 shared papers
- Régis Pomès and Gerold Schmitt-Ulms: 2 shared papers
- Régis Pomès and Holger Wille: 2 shared papers
- Frank Sicheri and Avi Chakrabartty: 1 shared paper
- Christopher Yip and Avi Chakrabartty: 1 shared paper
- Cheryl Arrowsmith and Avi Chakrabartty: 1 shared paper
- Daniel Durocher and Alba Guarne: 1 shared paper
- Daniel Durocher and Avi Chakrabartty: 1 shared paper
- Régis Pomès and Avi Chakrabartty: 1 shared paper
- Lewis Kay and Avi Chakrabartty: 1 shared paper
- Joel Watts and Avi Chakrabartty: 1 shared paper
- Gerold Schmitt-Ulms and Avi Chakrabartty: 1 shared paper
- Holger Wille and Avi Chakrabartty: 1 shared paper
- Julie Forman-Kay and Avi Chakrabartty: 1 shared paper
- Alba Guarne and Avi Chakrabartty: 1 shared paper
- Simon Sharpe and Avi Chakrabartty: 1 shared paper
- Avi Chakrabartty and Ying Lu: 1 shared paper
- Department of Biochemistry
- Department of Molecular Genetics
- Department of Medical Biophysics
- Tanz Centre for Research in Neurodegenerative Diseases
- Department of Chemical Engineering & Applied Chemistry
- Biochemistry Dept
- Department of Ophthalmology & Vision Sciences
Co-authors at University of Toronto, colored by department. Thicker lines mean more shared papers; select anyone to open their profile and their own map.
Ying Lu
Department of Ophthalmology & Vision Sciences
1 shared papers, latest 2004
Frank Sicheri
Department of Molecular Genetics
1 shared papers, latest 2016
Christopher Yip
Department of Chemical Engineering & Applied Chemistry
1 shared papers, latest 2014
Cheryl Arrowsmith
Department of Medical Biophysics
1 shared papers, latest 2004
Daniel Durocher
Department of Molecular Genetics
1 shared papers, latest 2016
Régis Pomès
Department of Biochemistry
1 shared papers, latest 2017
Lewis Kay
Department of Molecular Genetics
1 shared papers, latest 2017
Joel Watts
Tanz Centre for Research in Neurodegenerative Diseases
1 shared papers, latest 2017
Gerold Schmitt-Ulms
Tanz Centre for Research in Neurodegenerative Diseases
1 shared papers, latest 2017
Holger Wille
Biochemistry Dept
1 shared papers, latest 2017
Julie Forman-Kay
Department of Biochemistry
1 shared papers, latest 2017
Alba Guarne
Department of Biochemistry
1 shared papers, latest 2016
Simon Sharpe
Department of Biochemistry
1 shared papers, latest 2017
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Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.