Faculty profile

Jinrong Min

ResearcherPhysiologyUniversity of Toronto

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a University of Toronto directory, so their courses may be missing. Find their university profile.

Jinrong Min

Researcher

Physiology

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
14 publications in the last five years, latest in 2026.
Senior (last) author on 6 recent papers, a sign of leading a research group.
Principal investigator on 2 research grants (2 NSERC), most recently in 2021.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

115

Publications

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Biochemistry C-degron pathway gene regulation Molecular biology N-degron pathway Post-translational modification protein degradation protein science

Latest papers

Covalent allosteric inhibition of AARS1 lactyltransferase.
Nature communications · 2026 · senior author
Identification of novel covalent ligands that disrupt Acetyl-Lysine binding to the SETDB1 tudor domain.
Biochemical and biophysical research communications · 2026 · senior author
Structural basis for sequence-specific DNA recognition by a group IId WRKY transcription factor GhWRKY17 in cotton.
The Biochemical journal · 2026

All 115 publications

Latest funding

Molecular basis for the recognition of N- and C-degrons
NSERC · 2021 · Principal investigator
$200,000
Structural and functional studies of alpha-N-terminal methylation
NSERC · 2016 · Principal investigator
$190,000

All 2 grants and awards

115 publications.

Covalent allosteric inhibition of AARS1 lactyltransferase.

Huang Y, Liu S, Tian L, Tang Y, Dou Y, Wang H, Zheng T, Wang M, Li R, Wang Z, Zhou Z, Chen X, Min J

Nature communications2026Senior author

DOI: 10.1038/s41467-026-76732-9 PMID: 42744818

Identification of novel covalent ligands that disrupt Acetyl-Lysine binding to the SETDB1 tudor domain.

Ma J, Huang Y, Zheng T, Wang H, Li B, Liu S, Liu C, Chen X, Min J

Biochemical and biophysical research communications2026Senior author

DOI: 10.1016/j.bbrc.2026.153815 PMID: 42033939

Structural basis for sequence-specific DNA recognition by a group IId WRKY transcription factor GhWRKY17 in cotton.

Xiao Q, Wang Y, Shang X, Chen Y, Zhang M, Zhou Y, Huang X, Qin S, Min J, Xu G, Liu Y

The Biochemical journal2026

DOI: 10.1042/bcj20250191 PMID: 41569870

Therapeutic targeting of WDR5-MLL1 by EMBOW-derived peptides suppresses leukemia progression.

Zhang M, Chen M, Li P, Min J

Cell chemical biology2025Senior author

DOI: 10.1016/j.chembiol.2025.10.002 PMID: 41135522

An Adenosine Analogue Library Reveals Insights into Active Sites of Protein Arginine Methyltransferases and Enables the Discovery of a Selective PRMT4 Inhibitor.

Deng Y, Kim EJ, Song X, Kulkarni AS, Zhu RX, Wang Y, Bush M, Dong A, Noinaj N, Min J, Xu W, Huang R

Journal of medicinal chemistry2024

DOI: 10.1021/acs.jmedchem.4c01041 PMID: 39361813

A chemical probe to modulate human GID4 Pro/N-degron interactions.

Owens DDG, Maitland MER, Khalili Yazdi A, Song X, Reber V, Schwalm MP, Machado RAC, Bauer N, Wang X, Szewczyk MM, Dong C, Dong A, Loppnau P, Calabrese MF, Dowling MS, Lee J, Montgomery JI, O'Connell TN, Subramanyam C, Wang F, Adamson EC, Schapira M, Gstaiger M, Knapp S, Vedadi M, Min J, Lajoie GA, Barsyte-Lovejoy D, Owen DR, Schild-Poulter C, Arrowsmith CH

Nature chemical biology2024

DOI: 10.1038/s41589-024-01618-0 PMID: 38773330

Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex.

Yazdi AK, Perveen S, Dong C, Song X, Dong A, Szewczyk MM, Calabrese MF, Casimiro-Garcia A, Chakrapani S, Dowling MS, Ficici E, Lee J, Montgomery JI, O'Connell TN, Skrzypek GJ, Tran TP, Troutman MD, Wang F, Young JA, Min J, Barsyte-Lovejoy D, Brown PJ, Santhakumar V, Arrowsmith CH, Vedadi M, Owen DR

RSC medicinal chemistry2024

DOI: 10.1039/d3md00633f PMID: 38516600

A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.

Deng Y, Song X, Iyamu ID, Dong A, Min J, Huang R

Acta pharmaceutica Sinica. B2023

DOI: 10.1016/j.apsb.2023.07.022 PMID: 38045046

Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.

Liu K, Zhang J, Xiao Y, Yang A, Song X, Li Y, Chen Y, Hughes TR, Min J

The Journal of biological chemistry2023Senior author

DOI: 10.1016/j.jbc.2023.104734 PMID: 37086783

A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.

Liu Y, Iqbal A, Li W, Ni Z, Wang Y, Ramprasad J, Abraham KJ, Zhang M, Zhao DY, Qin S, Loppnau P, Jiang H, Guo X, Brown PJ, Zhen X, Xu G, Mekhail K, Ji X, Bedford MT, Greenblatt JF, Min J

Nature communications2022Senior author

DOI: 10.1038/s41467-022-33229-5 PMID: 36114190

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Jinrong Min

Research

Latest papers

Latest funding

Covalent allosteric inhibition of AARS1 lactyltransferase.

Identification of novel covalent ligands that disrupt Acetyl-Lysine binding to the SETDB1 tudor domain.

Structural basis for sequence-specific DNA recognition by a group IId WRKY transcription factor GhWRKY17 in cotton.

Therapeutic targeting of WDR5-MLL1 by EMBOW-derived peptides suppresses leukemia progression.

An Adenosine Analogue Library Reveals Insights into Active Sites of Protein Arginine Methyltransferases and Enables the Discovery of a Selective PRMT4 Inhibitor.

A chemical probe to modulate human GID4 Pro/N-degron interactions.

Chemical tools for the Gid4 subunit of the human E3 ligase C-terminal to LisH (CTLH) degradation complex.

A unique binding pocket induced by a noncanonical SAH mimic to develop potent and selective PRMT inhibitors.

Structural insights into DNA recognition by the BEN domain of the transcription factor BANP.

A small molecule antagonist of SMN disrupts the interaction between SMN and RNAP II.

Molecular basis for the recognition of N- and C-degrons

Structural and functional studies of alpha-N-terminal methylation

Frequent collaborators

Matthieu Schapira

Dalia Barsyte-Lovejoy

Alexei Savchenko

Yang Shen

Andrew Emili

Xiang-Jiao Yang

Jason Moffat

Rachel Harding

Ahmed Aman

Jack Greenblatt

Adam Frankel

Cheryl Arrowsmith

Karim Mekhail