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Paul Olguin

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Associate ProfessorDepartment of Molecular GeneticsUniversity of Toronto

Paul Olguin

Associate Professor

Department of Molecular Genetics

Temerty Faculty of Medicine

University of Toronto

Toronto, Ontario, Canada

Supervision signals

Professors usually supervise graduate students in their department's programs.
19 publications in the last five years, latest in 2026.
Senior (last) author on 4 recent papers, a sign of leading a research group.

These signals come from public records, including federal and provincial funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

Publications

5,340

Citations

Collaborators

Publications by year

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Signals and details

Research

Read how they describe their research on their University of Toronto profile.

Latest papers

Maternal obesity remodels nutrient transport transcriptional programs in early mouse embryonic and extraembryonic cell lineages
Molecular Metabolism · 2026 · senior author
Generation and characterization of a mouse model of Becker muscular dystrophy with a deletion of Dmd exons 52 to 55.
Disease models & mechanisms · 2025
Correction: A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy
Disease Models & Mechanisms · 2025

All 79 publications

79 publications.

Maternal obesity remodels nutrient transport transcriptional programs in early mouse embryonic and extraembryonic cell lineages

Amalia Caballero, Lijun Chi, Paul Delgado-Olguı́n

Molecular Metabolism2026Senior authorOpen Access

DOI: 10.1016/j.molmet.2026.102375 PMID: 42066955

Generation and characterization of a mouse model of Becker muscular dystrophy with a deletion of Dmd exons 52 to 55.

Perillat LOM, Wong TWY, Maino E, Ahmed A, Scott O, Hyatt E, Delgado-Olguin P, Visuvanathan S, Ivakine EA, Cohn RD

Disease models & mechanisms20256 citationsOpen Access

DOI: 10.1242/dmm.050595 PMID: 39099311

Correction: A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy

Thanda Wai, Ying Pei Wong, Abdalla Ahmed, Grace Meijuan Yang, Eleonora Maino, Sydney Steiman, Elzbieta Hyatt, Parry Chan, Kyle Lindsay, Nicole Wong, Diane Golebiowski, Joel Schneider, Paul Delgado-Olguı́n, Evgueni A. Ivakine, Ronald D. Cohn

Disease Models & Mechanisms2025Open Access

DOI: 10.1242/dmm.052372 PMID: 40184032

Lipid Nanoparticle Delivery of Mesenchymal Stromal Cell-Derived microRNA 187-3p as a First-in-Class Therapy for Myocardial Dysfunction in Sepsis

Amin M. Ektesabi, Maria Carolina Barbosa‐Silva, James N. Tsoporis, Samantha McWhirter, Chirag Manoj Vaswani, Yanis Mouloud, Logan W. C. Zettle, Abdalla Ahmed, Paul Delgado-Olguı́n, Sabrina Setembre Batah, Jean‐François Desjardins, Sahil Gupta, Greaton W. Tan, Jacqueline L. Pavelick, Yanbo Wang, Alexandre Todorovic Fabro, Phyllis Billia, Nikolaos Kavantzas, John C. Marshall, Kim Alexander Connelly, Shirley H. J. Mei, Lauralyn McIntyre, Duncan John Stewart, Howard M. Leong-Poi, Tatiana Maron-Gutierrez, Bernd Giebel, Gilbert C. Walker, Claúdia C. dos Santos

bioRxiv (Cold Spring Harbor Laboratory)2025Open Access

DOI: 10.1101/2025.09.09.674991

TRACKING THE PROGRESS: WOMEN’S PARTICIPATION ON CARDIOLOGY JOURNAL EDITORIAL BOARDS IN THE US AND EUROPE

Alena Gonzalez, Samantha Lo, Ariela Baur, Paul Delgado-Olguı́n, Michelle Nanni, Johanna Contreras

Journal of the American College of Cardiology2025Open Access

DOI: 10.1016/s0735-1097(25)03251-6

Molecular and Epigenetic Pathways Underlying Epithelial Damage and Repair in Necrotizing Enterocolitis via Multi-omics Approach

Yi Xiong, Andrea Zito, Haoyan Liang, George Biouss, Jielin Yang, Felicia Balsamo, M Yeganeh, Carol Lee, Dorothy Lee, Chenyi Wang, Nareh Tahmasian, Jinling Huang, Adam Minich, Mehrsa Feizi, Shiwen Wang, Yina Tian, Paolo De Coppi, Brian Thomas Kalish, Paul Delgado-Olguı́n, Haitao Zhu, Bo Li, Agostino Pierro

bioRxiv (Cold Spring Harbor Laboratory)2025Open Access

DOI: 10.1101/2025.04.17.647851

Template-assisted sequence knockin rescues skeletal and cardiac muscle function in a deletion model of Duchenne muscular dystrophy.

Fatehi S, Rok MJ, Marks RM, Huynh E, Kozman N, Truong HA, Chi L, Yan B, Khazeeva E, Delgado-Olguin P, Ivakine EA, Cohn RD

Molecular therapy : the journal of the American Society of Gene Therapy2025Open Access

DOI: 10.1016/j.ymthe.2025.05.005 PMID: 40340246

Loss of functional peroxisomes leads to increased mitochondrial biogenesis and reduced autophagy that preserve mitochondrial function.

Chi L, Lee D, Leung S, Hu G, Wen B, Delgado-Olguin P, Vissa M, Li R, Brumell JH, Kim PK, Bandsma RHJ

Cellular and molecular life sciences : CMLS202319 citationsOpen Access

DOI: 10.1007/s00018-023-04827-3 PMID: 37338571

KDM8 epigenetically controls cardiac metabolism to prevent initiation of dilated cardiomyopathy.

Ahmed A, Syed JN, Chi L, Wang Y, Perez-Romero C, Lee D, Kocaqi E, Caballero A, Yang J, Escalante-Covarrubias Q, Ishimura A, Suzuki T, Aguilar-Arnal L, Gonzales GB, Kim KH, Delgado-Olguín P

Nature cardiovascular research202318 citationsSenior authorOpen Access

DOI: 10.1038/s44161-023-00214-0 PMID: 38665902

Prevention of early-onset cardiomyopathy in Dmd exon 52–54 deletion mice by CRISPR-Cas9-mediated exon skipping

Matthew J. Rok, Tatianna Wai Ying Wong, Eleonora Maino, Abdalla Ahmed, Grace Meijuan Yang, Elzbieta Hyatt, Kyle Lindsay, Sina Fatehi, Ryan M. Marks, Paul Delgado-Olguı́n, Evgueni A. Ivakine, Ronald D. Cohn

Molecular Therapy — Methods & Clinical Development202310 citationsOpen Access

DOI: 10.1016/j.omtm.2023.07.004 PMID: 37545481

Profile data last refreshed on September 29, 2026 from the university directory, publication records and public research funding records.

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Paul Olguin

Research

Latest papers

Maternal obesity remodels nutrient transport transcriptional programs in early mouse embryonic and extraembryonic cell lineages

Generation and characterization of a mouse model of Becker muscular dystrophy with a deletion of Dmd exons 52 to 55.

Correction: A novel mouse model of Duchenne muscular dystrophy carrying a multi-exonic Dmd deletion exhibits progressive muscular dystrophy and early-onset cardiomyopathy

Lipid Nanoparticle Delivery of Mesenchymal Stromal Cell-Derived microRNA 187-3p as a First-in-Class Therapy for Myocardial Dysfunction in Sepsis

TRACKING THE PROGRESS: WOMEN’S PARTICIPATION ON CARDIOLOGY JOURNAL EDITORIAL BOARDS IN THE US AND EUROPE

Molecular and Epigenetic Pathways Underlying Epithelial Damage and Repair in Necrotizing Enterocolitis via Multi-omics Approach

Template-assisted sequence knockin rescues skeletal and cardiac muscle function in a deletion model of Duchenne muscular dystrophy.

Loss of functional peroxisomes leads to increased mitochondrial biogenesis and reduced autophagy that preserve mitochondrial function.

KDM8 epigenetically controls cardiac metabolism to prevent initiation of dilated cardiomyopathy.

Prevention of early-onset cardiomyopathy in Dmd exon 52–54 deletion mice by CRISPR-Cas9-mediated exon skipping

Frequent collaborators

Paul Delgado Olguin

Agostino Pierro

Darius Bagli

Philip Sherman

Jason Fish

Evgueni Ivakine

John Sled

Ronald Cohn

Lindsay Cahill

Augusto Zani

Kyoung-Han Kim

Rosanna Weksberg

Shaiya Robinson

Myron Cybulsky

Kim Connelly

Mansoor Husain

Ian Scott

Lena Serghides

Sevan Hopyan

John Brumell

Alan Daneman