Faculty profile

Yves De Koninck

ResearcherUniversité Laval

This profile is built from public research funding records (CIHR, NSERC and SSHRC) and PubMed. We have not imported them from a Université Laval directory, so their courses may be missing. Find their university profile.

Yves De Koninck

Researcher

Health Sciences

Université Laval

Quebec City, Quebec, Canada

Supervision signals

Has led research grants, which requires an independent research appointment. Ask their department whether they supervise graduate students.
32 publications in the last five years, latest in 2026.
Senior (last) author on 8 recent papers, a sign of leading a research group.
Principal investigator on 29 research grants (20 CIHR, 9 NSERC), most recently in 2024.
Supervisor on 1 trainee award (1 CIHR), most recently in 2008.

These signals come from public records, including CIHR, NSERC and SSHRC funding decisions. Ask the professor or the graduate program whether they are taking new students.

Academic metrics

108

Publications

Citations

Collaborators

Grants

Publications by year

Counts cover the publications linked to this profile. Citations and the h-index appear when the source records them.

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Signals and details

Research

Chronic Pain Electrophysiology Spinal Cord Cellular Imaging Optogenetics Fluorescence Fiber Optics Synaptic Physiology

Latest papers

Deterministic wet etching of aspheric fiber microlenses with tunable conic geometry for tailored optical functionality.
Nature communications · 2026 · senior author
Excessive inhibition in the medial prefrontal cortex contributes to cognitive susceptibility in aging.
Neurobiology of disease · 2026 · senior author
A specialized population of hair afferents dedicated to transmitting mechanical itch.
Neuron · 2026

All 108 publications

Latest funding

Spinal circuits encoding normal and pathological thermoception
CIHR · 2026 · Co-investigator
$841,500
Cortical GABAergic control in the comorbidity of chronic pain and mood disorders
CIHR · 2024 · Nominated PI
$1,039,250
KCC2 as a therapeutic target for neuropathic pain
CIHR · 2024 · Nominated PI
$1,181,926

All 40 grants and awards

108 publications.

Deterministic wet etching of aspheric fiber microlenses with tunable conic geometry for tailored optical functionality.

Kim S, Keramidis I, Plasencia-Fernandez I, Alonso J, Brochoire L, Bories C, Barbeau A, Messaddeq Y, De Koninck Y

Nature communications2026Senior author

DOI: 10.1038/s41467-026-75331-y PMID: 42706254

Excessive inhibition in the medial prefrontal cortex contributes to cognitive susceptibility in aging.

Keramidis I, Desrosiers P, Verreault AA, Sansonetti R, Hazrati R, Godin AG, De Koninck Y

Neurobiology of disease2026Senior author

DOI: 10.1016/j.nbd.2026.107385 PMID: 41962851

A specialized population of hair afferents dedicated to transmitting mechanical itch.

Fatima M, Lee H, Cha H, Hor CC, Wang F, Liu J, Damblon J, Zhang W, Qu K, Nagai Y, Dinh A, Wu Z, Ajimal R, Xiong AE, Chai M, Asmar A, Cai W, Zhou X, Balaji A, Pan H, Horwitz L, Tsoi LC, Hu H, Xu XZS, De Koninck Y, Duan B

Neuron2026

DOI: 10.1016/j.neuron.2026.05.017 PMID: 42242217

Runx1 transcription factor modulates opioid analgesia and withdrawal in humans and rodents.

Leduc-Pessah H, McAllister BB, Sinha S, Stokes-Heck S, Nishizawa D, Fan CY, St-Pierre MK, Bradaia A, Defaye M, Burma NE, Damblon J, Muñoz-Pino E, Visser F, Dorion MF, Healy LM, Tang YM, Canet-Pons J, van den Hoogen NJ, Zhang Z, Antunes FTT, Piscopo VEC, Medina M, Fukuda KI, Ichinohe T, Nagashima M, Hayashida M, Johnson E, Agrawal A, Degenhardt L, Martin NG, Zamponi GW, Nelson EC, Altier C, Tremblay ME, Bousman C, Stifani S, De Koninck Y, Ikeda K, Biernaskie J, Trang T

Neuron2026

DOI: 10.1016/j.neuron.2025.11.018 PMID: 41619726

Nucleus raphe magnus serotonin neurones bidirectionally control spinal nociceptive transmission in mice.

Grivet Z, Verboven A, Aby F, Bouali-Benazzouz R, Dhellemmes T, Perrot E, Beyeler A, Heisler LK, Balia M, Battefeld A, Martin H, Retailleau A, Maingret F, Fioramonti X, Landry M, De Koninck Y, Benazzouz A, Fossat P

British journal of anaesthesia2026

DOI: 10.1016/j.bja.2026.03.069 PMID: 42173713

Excitability properties of cardiac calbindin neurons: Identifying a unique neuronal population.

Lizot G, Bescond J, De Koninck Y, Chahine M, Bois P, Faivre JF, Chatelier A

Heart rhythm2026

DOI: 10.1016/j.hrthm.2025.04.007 PMID: 40221111

Recommendations for the inclusion and study of sex and gender in research.

Finn DP, McGuire BE, Beggs S, Boerner KE, Davis KD, Defrin R, De Koninck Y, Devan H, Donovan R, Fetter E, Flor H, Fullen BM, Healy CR, Keogh E, Kuner R, Kunz M, Lane RM, Lautenbacher S, Mayer EA, Mogil JS, O'Mahony SM, O'Sullivan K, Riordan L, Salter MW, Scarlatti F, Shorten G, Sluka KA, Stinson JN, Vowles KE, Walker SM, Yalcin I, Roche M

Nature neuroscience2026

DOI: 10.1038/s41593-025-02164-1 PMID: 41461929

Decreased KCC2 expression in the human spinal dorsal horn associated with chronic pain and long-term opioid use.

Davis OC, Ferland S, Lorenzo LE, Murray-Lawson C, Shiers S, Yousuf MS, Dedek A, Tsai EC, Vines E, Horton P, Cervantes A, Khan T, Funk G, Dussor G, Godin AG, Ferrini F, De Koninck Y, Hildebrand ME, Price TJ

Pain2025

DOI: 10.1097/j.pain.0000000000003700 PMID: 40667986

Chronic optogenetic activation of hippocampal CA1 neurons triggers Alzheimer's disease-like proteomic remodeling.

Keramidis I, Samiotaki M, Sansonetti R, Alonso J, Desrosiers P, Papanikolopoulou K, De Koninck Y

iScience2025Senior author

DOI: 10.1016/j.isci.2025.113454 PMID: 41169497

The gut microbiota promotes pain in fibromyalgia.

Cai W, Haddad M, Haddad R, Kesten I, Hoffman T, Laan R, Westfall S, Defaye M, Abdullah NS, Wong C, Brown N, Tansley S, Lister KC, Hooshmandi M, Wang F, Lorenzo LE, Hovhannisyan V, Ho-Tieng D, Kumar V, Sharif B, Thurairajah B, Fan J, Sahar T, Clayton C, Wu N, Zhang J, Bar-Yoseph H, Pitashny M, Krock E, Mogil JS, Prager-Khoutorsky M, Séguéla P, Altier C, King IL, De Koninck Y, Brereton NJB, Gonzalez E, Shir Y, Minerbi A, Khoutorsky A

Neuron2025

DOI: 10.1016/j.neuron.2025.03.032 PMID: 40280127

Spinal circuits encoding normal and pathological thermoception

Co-investigatorCIHR2026Project Grant

Principal investigators: Wang, Feng

Keywords: Chronic Pain; Cold Hypersensitivity; In Vivo Functional Imaging; Mice Behavior Testing; Neural Circuits; Sensory Encoding; Spinal Cord Projection Neurons; Thermosensation

$841,500

Cortical GABAergic control in the comorbidity of chronic pain and mood disorders

Nominated PICIHR2024Project Grant

Principal investigators: De Koninck, Yves; Paquet, Marie-Eve; Yalcin-Christmann, Ipek

Keywords: Anterior Cingulate Cortex; Anxio-Depressive Behaviour; Behavioural Assesment; Chronic Pain; Electrophysiology; Gaba; Glutamate; Inhibition; Optogenetics; Sodium Channels

$1,039,250

KCC2 as a therapeutic target for neuropathic pain

Nominated PICIHR2024Project Grant

Principal investigators: De Koninck, Yves

Keywords: Cell Signalling; Cellular Imaging; Chronic Pain; Electrophysiology; Inhibition; Nociception; Plasticity; Sensory Physiology; Spinal Cord; Synaptic Physiology

$1,181,926

Multi-core tapered single fiber for multi-channel optical interrogation

Nominated PICIHR2024Cat Gr: Develop./validation of new biomedical techniques/technolo.- General Pool

Principal investigators: De Koninck, Yves; Messaddeq, Younès

Keywords: Cell Signaling; Fiber Optics; Fluorescence; Material Science; Neurophysiology; Optogenetics

$299,998

Direct write photolithography for advanced microsystems: chemistry to life sciences

Co-investigatorNSERC2024Research Tools and Instruments

Principal investigators: Greener, Jesse

Keywords: Bacteriology; Biomedical materials; Biomedical sensors and implants; Lab-on-a-chip (electrochemistry, spectroscopy, microscopy); Microfluidics, MEMS and Micro-electronics; Microscale reactors and assays; Optoelectronics; Photolithography; Sustainable plastics; Water quality

$150,000

Canada Research Chair - Tier 1

Nominated PICIHR2022Canada Research Chairs - CIHR Funded - Tier 1

Principal investigators: De Koninck, Yves

Keywords: Crc

$1,400,000

Lasers femtosecondes tout-fibre pour applications en micro-usinage et en biophotonique

Principal investigatorNSERC2021Alliance Grants

Principal investigators: De Koninck, Yves JG

$250,000

Novel technology for quality control of viral vector particles

Principal investigatorNSERC2021Alliance Grants

Principal investigators: De Koninck, Yves JG

$995,300

Tools to decipher neuronal signalling and computation

Principal investigatorNSERC2020Discovery Grants Program - Individual

Principal investigators: De Koninck, Yves

Keywords: neuroscience; photonics; sensory physiology; membrane biophysics; noise analysis; fluorescence; non-linear microscopy; optogenetics; fibre optics; numerical simulations

$300,000

A prospective translational model of the therapeutic potential of cannabidiol in reducing acute pain symptoms and opioid usage following traumatic injury.

Principal investigatorCIHR2019Team Grant: Cannabis Research in Priority Areas - IMHA Pain

Principal investigators: De Beaumont, Louis; Arbour, Caroline; Bernard, Francis; De Koninck, Yves; Gendron, Louis; Lavigne, Gilles J; Near, Jamie; Pinard, Anne-Marie; Rouleau, Dominique; Williamson, David

Keywords: Cannabidiol Treatment; Co-Analgesia; Hyperalgesia; Inflammation; Opioid; Pain; Sex Differences; Translational Model; Traumatic Injury

$1,499,925

From CIHR, NSERC and SSHRC funding decisions: CIHR since 2008, NSERC since 1991 and SSHRC since 1998, including their latest published competition results.

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Yves De Koninck

Research

Latest papers

Latest funding

Deterministic wet etching of aspheric fiber microlenses with tunable conic geometry for tailored optical functionality.

Excessive inhibition in the medial prefrontal cortex contributes to cognitive susceptibility in aging.

A specialized population of hair afferents dedicated to transmitting mechanical itch.

Runx1 transcription factor modulates opioid analgesia and withdrawal in humans and rodents.

Nucleus raphe magnus serotonin neurones bidirectionally control spinal nociceptive transmission in mice.

Excitability properties of cardiac calbindin neurons: Identifying a unique neuronal population.

Recommendations for the inclusion and study of sex and gender in research.

Decreased KCC2 expression in the human spinal dorsal horn associated with chronic pain and long-term opioid use.

Chronic optogenetic activation of hippocampal CA1 neurons triggers Alzheimer's disease-like proteomic remodeling.

The gut microbiota promotes pain in fibromyalgia.

Spinal circuits encoding normal and pathological thermoception

Cortical GABAergic control in the comorbidity of chronic pain and mood disorders

KCC2 as a therapeutic target for neuropathic pain

Multi-core tapered single fiber for multi-channel optical interrogation

Direct write photolithography for advanced microsystems: chemistry to life sciences

Canada Research Chair - Tier 1

Lasers femtosecondes tout-fibre pour applications en micro-usinage et en biophotonique

Novel technology for quality control of viral vector particles

Tools to decipher neuronal signalling and computation

A prospective translational model of the therapeutic potential of cannabidiol in reducing acute pain symptoms and opioid usage following traumatic injury.

Frequent collaborators

Alfredo Ribeiro-Da-Silva

Feng Wang

Arkady Khoutorsky

Ji Zhang

Paul De Koninck

Marco Battaglia

Patrick Desrosiers

Marie-Eve Paquet

Judy Illes

Benoit Gosselin

Tuan Trang

Luda Diatchenko

Masha Prager-Khoutorsky

Flavie Lavoie-Cardinal

Mohamed Chahine

Christophe Altier

Steve Lacroix

Paul Isenring

Pierre Marquet

Emerson Krock

Younès Messaddeq

Joel Katz

Chad Bousman

Clare Murray-Lawson

Fiona Campbell

Catherine Mercier

Jaideep Bains

Patricia Conrod

Marie-Christine Ouellet

François Routhier

Serge Rivest

Philippe Séguéla

Andrew Emili

Chelsea Gabel

Santiago Costantino

Stefano Stifani

Artur Kania

Nahum Sonenberg

Jennifer Stinson